Clinical trials: Anesthesia; Functional
Epidural Anesthesia, Infection
The Effect of Combined General-epidural vs General Anaesthesia on Postoperative Gastrointestinal Surgery
Sixty neonates and infants will be enrolled and randomised into two groups of n=30 each . For their surgical procedures, one group general (GA) anaesthesia the second group will receive a combined general and epidural anaesthesia…
- Conditions
- Epidural Anesthesia, Infection, Infant, Newborn, Diseases
- Trial name
- NCT03056261
- Testing
- Combined general and epidural, General anaesthesia
- Volunteers
- 60 people
- Sponsor
- Bnai Zion Medical Center
Anesthesia; Functional
Laryngeal Mask Airway With Video-stylet
In this randomized controlled trial, we aimed to compare the efficacy of video-stylet guided laryngeal mask airway real time insertion technique with the standard recommended index finger-guided insertion technique in pediatric…
- Trial name
- NCT02937337
- Testing
- Laryngeal mask insertion with videostylet guided technique, Laryngeal mask insertion with standard blind technique
- Where
- South Korea
- Volunteers
- 108 people
- Sponsor
- Seoul National University Hospital
Apnea, Anesthesia
Functional Residual Capacity Under Apnoeic Oxygenation with Different Flow Rates in Children
During induction of general anaesthesia physiological breathing stops and needs to be artificially established with facemask ventilation, and finally tracheal intubation or placement of a supraglottic airway.
- Conditions
- Apnea, Anesthesia, Intubation Complication, Children, Only
- Trial name
- FUTURE (NCT05672329)
- Testing
- 0.2 L/kg/min, FiO2 1.0 + continuous jaw thrust, 2 L/kg/min, FiO2 1.0 + continuous jaw thrust, 4 L/kg/min, FiO2 1.0 + continuous jaw thrust
- Where
- Switzerland
- Volunteers
- 108 people
- Sponsor
- Thomas Riva
Postoperative Cognitive Dysfunction
Effects of General Anesthesia on Brain FC and Cognition in Children With Potential Neurological Damage
Postoperative Cognitive Dysfunction(POCD)is a common postoperative complications, existing clinical research focused on the adult patients, ignoring that the developing human brain with underlying neurological impairments may be…
- Trial name
- NCT05602311
- Testing
- General anesthetic
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Kasai Operation, Biliary Atresia
The Comparison of Desflurane and Sevoflurane on Postoperative Recovery and Hepatic Function of Biliary Atresia Patients During Kasai Operation
Biliary atresia (BA) is a perinatal disease of unclear etiology, characterized by inflammation and obliteration of intrahepatic and extrahepatic bile ducts, leading to cholestasis and cirrhosis.
- Trial name
- NCT01443572
- Testing
- desflurane anesthetics, sevoflurane anesthetics
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Yonsei University
Heart Rate Low, Anesthesia; Functional
A Study on Safety and Efficacy of Propofol in Small Children Under 2 Years of Age
This retrospective study the safety and efficacy of intravenous propofol used in children under 2 years of age during general anesthesia for surgery.
- Trial name
- NCT03132688
- Testing
- Propofol
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Labour Analgesia, Epidural Anaesthesia
An Observational Study Investigating the Positioning of Epidural Catheters and Their Function During Labour Analgesia
This is a small observational study investigating the physical changes that occur to epidural catheters after insertion for obstetric anaesthesia.
- Trial name
- NCT02924779
- Testing
- No intervention
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Rotkreuzklinikum München gGmbH
Anesthesia
Perioperative Audio for Anaesthesia
Induction and emergence from propofol can be a difficult process for patients and healthcare workers, and long recovery times in particular can limit the rate of care.
- Trial name
- NCT05291832
- Testing
- Brain.fm Music, Spectrally-matched Noise
- Where
- United States
- Volunteers
- 329 people, healthy volunteers welcome
- Sponsor
- Brain.fm, Inc.
Anesthesia; Functional
Neuromuscular Blockade Reversal Agent Effect on Postoperative Cognitive Function and Behaviour in Children
The aim of this prospective randomized study is to investigate comparatively the effect of neostigmine-atropine versus sugammadex on speed and quality of recovery and on postoperative cognitive function \& behavior in children…
- Trial name
- NCT02455921
- Testing
- neostigmine - atropine, Sugammadex
- Where
- Greece
- Volunteers
- 200 people
- Sponsor
- Attikon Hospital
Reference Values
Reference Values for Pulse Induced Continuous Cardiac Output (PiCCO) Variables in Children
Pulse induced continuous cardiac output (PiCCO) is an established technology for measurement of advanced hemodynamic variables in critically ill patients.
- Trial name
- NCT01283529
- Where
- Norway
- Volunteers
- 31 people
- Sponsor
- Oslo University Hospital
Cognitive Deficits, Cognitive Ability, General
Childhood Anesthesia and Cognitive Function
The purpose of this study is to determine whether pediatric anesthesia is associated with long-term hippocampal dysfunction
- Trial name
- UCSF-Anes-01 (NCT01359215)
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cerebrovascular Accident
Hand Exercise and Upper Arm Anesthesia to Improvements Hand Function in Chronic Stroke Patients
This study will examine the effectiveness of an experimental treatment to improve hand function in patients who have had a stroke affecting one side of the body.
- Trial name
- NCT00006414
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
ADHD - Attention Deficit Disorder With Hyperactivity
Clinical Study of Non-invasive 40-Hz Audiovisual Stimulation Guided by Gamma EEG Monitoring for Promoting Perioperative Brain Function Recovery in Children
Exposure to general anesthesia during early brain development has emerged as an important risk factor for long-term attention-deficit/hyperactivity disorder (ADHD)-like behaviors and learning difficulties in school-aged children.
- Trial name
- NCT07719465
- Testing
- 40-Hz non-invasive synchronized audiovisual stimulation
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- General Hospital of Ningxia Medical University
Liver Functions Tests
Desflurane and Sevoflurane in Pediatrics With Elevated Liver Enzymes
It is designed to compare effects of inhaled anaesthetic desflurane and sevoflurane on liver functions in pediatric cancer patients
- Trial name
- NCT04775212
- Testing
- Desflurane, Sevoflurane
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- National Cancer Institute, Egypt
Pediatric Retinoblastoma, Retinoblastoma
Determining Whether Multiple Anesthesia Exposures Affect Cognitive Function for Retinoblastoma Patients
The purpose of this study is to see if there is a difference between the development of the brain (neurodevelopment) in children who have been treated for retinoblastoma with multiple anesthetic exposures, compared with brain…
- Trial name
- NCT03546387
- Testing
- Wechsler Intelligence Scale for Children, Fifth Edition (WISC-V), California Verbal Learning Test, Children's Version, Beery Developmental Test of Visual Motor Integration, 6th edition
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Pupillary Functions, Abnormal
Effects of Volatile and Intravenous Anesthetics on Pupillary Function
To compare of effects of volatile and intravenous anesthetics on pupillary function during general anesthesia in children
- Trial name
- NCT03987529
- Testing
- sevoflurane, propofol
- Where
- South Korea
- Volunteers
- 22 people
- Sponsor
- Seoul National University Hospital
Pain
Functional Near Infrared Spectroscopy to Detect Pain in Young Children Under General Anesthesia
This is a three-phase pilot prospective study to develop a devise capable of detecting changes in cortical blood volume and oxygenation due to noxious stimuli.
- Trial name
- NCT04362423
- Testing
- fNIRS
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Anesthesia, Conduction, Nerve Block
Neurologic Complications in Peripheral Regional Anesthesia - An Evaluation Based on a Standardized Protocol
To evaluate the incidence of neurologic complications as a consequence of peripheral regional anesthesia, all patients receiving peripheral nerve blocks will be evaluated according to a standardized protocol screening pain…
- Conditions
- Anesthesia, Conduction, Nerve Block, Adverse Effects
- Trial name
- NCT00445016
- Testing
- peripheral regional anesthesia
- Where
- Germany
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- BG Unfallklinik Murnau
Renal Injury, Child, Only
Comparison Between Different Anaesthesia Techniques Protecting Renal Function in Children Undergoing Radicle Nephrectomy
Up to date, Renal Cell carcinomas (RCC) are one of the prevalent primary renal neoplasms affecting children \& surgical radical nephrectomy is the conventional standard of care, as the choice of non-surgical modalities like…
- Trial name
- NCT05271253
- Testing
- Dexmedetomidine, bupivacaine, normal Saline
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Alexandria University
Vaginismus
Spinal Anesthesia Facilitated Sexual Intercourse As A Treatment Option For Vaginismus
Painful sex continues to be a relationship issue and can lead to marital dys-harmony. Other consequences include infertility, low self-esteem, depression and anxiety.Our study shows that spinal anesthesia is an effective last…
- Trial name
- NCT04436172
- Testing
- spinal anesthesia
- Volunteers
- 20 people
- Sponsor
- Karachi Medical and Dental College