Clinical trials: Anesthesia; Functional
Anesthesia
Perioperative Audio for Anaesthesia
Induction and emergence from propofol can be a difficult process for patients and healthcare workers, and long recovery times in particular can limit the rate of care.
- Trial name
- NCT05291832
- Testing
- Brain.fm Music, Spectrally-matched Noise
- Where
- United States
- Volunteers
- 329 people, healthy volunteers welcome
- Sponsor
- Brain.fm, Inc.
Liver Functions Tests
Desflurane and Sevoflurane in Pediatrics With Elevated Liver Enzymes
It is designed to compare effects of inhaled anaesthetic desflurane and sevoflurane on liver functions in pediatric cancer patients
- Trial name
- NCT04775212
- Testing
- Desflurane, Sevoflurane
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- National Cancer Institute, Egypt
Anesthesia; Functional
Neuromuscular Blockade Reversal Agent Effect on Postoperative Cognitive Function and Behaviour in Children
The aim of this prospective randomized study is to investigate comparatively the effect of neostigmine-atropine versus sugammadex on speed and quality of recovery and on postoperative cognitive function \& behavior in children…
- Trial name
- NCT02455921
- Testing
- neostigmine - atropine, Sugammadex
- Where
- Greece
- Volunteers
- 200 people
- Sponsor
- Attikon Hospital
Neuromuscular Block, Residual
Diaphragm Function After Reversal of Rocuronium-induced Neuromuscular Blockade With Sugammadex or Neostigmine in Children
This study is to evaluate the recovery of diaphragm function and atelectasis after reversal of neuromuscular blockade with Neostigmine and Sugammadex using lung ultrasound and diaphragm ultrasound for children aged 2 to 7 who are…
- Trial name
- NCT05724550
- Testing
- Sugammadex, Neostigmine
- Where
- South Korea
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Retinoblastoma, Neurocognitive Dysfunction
Cognitive Functioning and Health Related Quality of Life in Retinoblastoma Survivors
A retrospective crosssectional observational study of the effects of oncological treatment and frequent general anesthesia on neuropsychological development, psychosocial functioning (in terms of anxiety, depression, peer…
- Conditions
- Retinoblastoma, Neurocognitive Dysfunction, Health-Related Behavior
- Trial name
- RbNeuroQoL (NCT06227962)
- Testing
- Neuropsychological assesment, Psychosocial functioning and quality of life (questionnaires), Parental psychosocial functioning (questionnaires)
- Where
- Netherlands
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Amsterdam University Medical Center
Anesthesia, Pulmonary Function Test, Preoperative
Prognostic Significance of Pulmonary Function Tests in Adolescent İdiopathic Scoliosis Surgery
Adolescent idiopathic scoliosis (AIS) is a three-dimensional structural deformity of the spine, the etiology of which is not clearly known, and can be seen from the age of 10 until the skeletal system matures.
- Conditions
- Anesthesia, Pulmonary Function Test, Preoperative, Adolescent Idiopathic Scoliosis
- Trial name
- NCT06756880
- Testing
- Pulmonary function test
- Where
- Turkey (Türkiye)
- Volunteers
- 165 people
- Sponsor
- Ankara City Hospital Bilkent
Anesthesia, Conduction, Nerve Block
Neurologic Complications in Peripheral Regional Anesthesia - An Evaluation Based on a Standardized Protocol
To evaluate the incidence of neurologic complications as a consequence of peripheral regional anesthesia, all patients receiving peripheral nerve blocks will be evaluated according to a standardized protocol screening pain…
- Conditions
- Anesthesia, Conduction, Nerve Block, Adverse Effects
- Trial name
- NCT00445016
- Testing
- peripheral regional anesthesia
- Where
- Germany
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- BG Unfallklinik Murnau
Flexor Tendon Rupture
Comparison Between Functional Outcomes of Flexor Tendon Repair Under WALANT and Brachial Plexus Block
Although outcomes after flexor tendon repair have reportedly improved with modern treatment, complications are common. Early passive and active motion protocols have improved outcomes of flexor tendon repairs.
- Trial name
- NCT06149962
- Testing
- FLEXOR TENDON REPAIR
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
Cardiac Surgery, Postoperative Cognitive Dysfunction
The Effects of Dexmedetomidine on Postoperative Cognitive Function in Open Heart Surgery
To assess the impact of Dexmedetomidine on postoperative cognitive function and serum Neuron Specific Enolase levels as an indicator of neuronal injury in patients undergoing open heart surgery
- Conditions
- Cardiac Surgery, Postoperative Cognitive Dysfunction, Neurologic Manifestations
- Trial name
- NCT06655025
- Testing
- Dexmedetomidine
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Sohag University
Traumatic Brain Injury, Subarachnoid Hemorrhage
Comparison of Narcotrend and Cerebral Function Analysing Monitor in Intensive Care to Monitor Seizures and Deep Sedation
A study in the use of the Narcotrend depth of anaesthesia monitor to record a) seizures, and b) monitor a level of sedation referred to as 'burst suppression', in sedated patients in the adult and paediatric intensive care.
- Conditions
- Traumatic Brain Injury, Subarachnoid Hemorrhage, Intracerebral Haemorrhage, Encephalitis
- Trial name
- NCT06067750
- Testing
- Narcotrend compared to Cerebral Function Analysing Monitor (CFAM)
- Where
- United Kingdom
- Volunteers
- 44 people
- Sponsor
- Nottingham University Hospitals NHS Trust
Anesthesia
The Effect of Propofol or Etomidate on Cognitive Function for 1-3 Years Old Children
Based on China's guangxi guilin for a hernia operation in 1 to 3 years old preschool children propofol and etomidate on behavioral and cognitive function after intravenous anesthesia in according to beta protein in serum and…
- Trial name
- NCT02199990
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Guilin Medical University, China
ADHD - Attention Deficit Disorder With Hyperactivity
Clinical Study of Non-invasive 40-Hz Audiovisual Stimulation Guided by Gamma EEG Monitoring for Promoting Perioperative Brain Function Recovery in Children
Exposure to general anesthesia during early brain development has emerged as an important risk factor for long-term attention-deficit/hyperactivity disorder (ADHD)-like behaviors and learning difficulties in school-aged children.
- Trial name
- NCT07719465
- Testing
- 40-Hz non-invasive synchronized audiovisual stimulation
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- General Hospital of Ningxia Medical University
Down Syndrome
The Effects of Inhalational Anaesthetics in Cognitive Functions in Down Syndrome Patients
Recovery of the cognitive functions and recovery features after general anaesthesia in Down syndrome patients. A comparison of Sevoflurane and Desflurane.
- Trial name
- NCT02971254
- Testing
- Sevoflurane, Desflurane
- Where
- Greece
- Volunteers
- 39 people
- Sponsor
- Asklepieion Voulas General Hospital
Renal Failure, Anesthesia
Renal Function During Pediatric Anesthesia
It is known that volatile anesthesia, such as sevoflurane, retain water and that this appears more pronounced in children. However, the mechanisms for this effect is unknown and it is not clear if the commonly used anesthetic…
- Trial name
- NCT02571426
- Testing
- Sevoflurane, propofol
- Where
- Sweden
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Neurodevelopmental Disorders, Child Behavior
Neurodevelopmental Outcome After Prenatal Anesthesia
In 2016, the US Food and Drug Administration raised concerns about the potential negative effects of anesthesia exposure on neurodevelopment in children during pregnancy or before the age of three.
- Trial name
- NCT06052878
- Testing
- Parental telephone interview with standardized parental questionnaire from the "Behaviour Rating Inventory of Executive Function" (BRIEF), Parental questionnaire about their child's cognitive functioning in their daily life and medical history.
- Where
- France
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Pupillary Functions, Abnormal
Effects of Volatile and Intravenous Anesthetics on Pupillary Function
To compare of effects of volatile and intravenous anesthetics on pupillary function during general anesthesia in children
- Trial name
- NCT03987529
- Testing
- sevoflurane, propofol
- Where
- South Korea
- Volunteers
- 22 people
- Sponsor
- Seoul National University Hospital
Epidural Anesthesia, Infection
The Effect of Combined General-epidural vs General Anaesthesia on Postoperative Gastrointestinal Surgery
Sixty neonates and infants will be enrolled and randomised into two groups of n=30 each . For their surgical procedures, one group general (GA) anaesthesia the second group will receive a combined general and epidural anaesthesia…
- Conditions
- Epidural Anesthesia, Infection, Infant, Newborn, Diseases
- Trial name
- NCT03056261
- Testing
- Combined general and epidural, General anaesthesia
- Volunteers
- 60 people
- Sponsor
- Bnai Zion Medical Center
Renal Blood Flow, Anesthesia
MR-Evaluation of Renal Function in Anesthetized Pediatric Patients
The goal of this study is to investigate the effect of the anesthetic agents sevoflurane or propofol on the blood flow and oxygen delivery to the kidneys.
- Conditions
- Renal Blood Flow, Anesthesia, MRI, Renal Oxygenation
- Trial name
- MERAPED (NCT06876870)
- Testing
- Anesthesia Maintenance Agent
- Volunteers
- 50 people
- Sponsor
- Uppsala University
Vaginismus
Spinal Anesthesia Facilitated Sexual Intercourse As A Treatment Option For Vaginismus
Painful sex continues to be a relationship issue and can lead to marital dys-harmony. Other consequences include infertility, low self-esteem, depression and anxiety.Our study shows that spinal anesthesia is an effective last…
- Trial name
- NCT04436172
- Testing
- spinal anesthesia
- Volunteers
- 20 people
- Sponsor
- Karachi Medical and Dental College
Anesthesia; Functional
Unwanted Penile Engorgement in Pediatric Patients Under Anesthesia.
Penile engorgement during intraoperative period is of rare occurrence however when do happens, leads to difficulty in performing and even cancellation of elective urogenital surgery.
- Trial name
- NCT03438253
- Testing
- spinal anaesthesia
- Volunteers
- 386 people
- Sponsor
- Aligarh Muslim University