Clinical trials: Anesthesia; Reaction
Cornea, Anesthesia; Reaction
The Effects of Nitrogen Protoxide and Oxygen on Corneal Endothelial in Pediatric Patients
To evaluate the mean changes in Endothelial Cell and Corneal pachymetry in eyes that operated under N2O + sevoflurane and O2 + sevoflurane general anesthesia.
- Trial name
- NCT03006211
- Testing
- Nitrogen protoxide, Oxygen
- Volunteers
- 40 people
- Sponsor
- Inonu University
Inguinal Hernia, Cryptorchidism
Caudal Versus Intravenous Dexmedetomidine for Supplementation of Caudal Analgesia in Children
The purpose of this study is to compare the effects of caudal dexmedetomidine with intravenous dexmedetomidine on caudal levobupivacaine analgesia in children undergoing lower abdominal surgeries.
- Trial name
- NCT01701778
- Testing
- Caudal Dexmedetomidine, Intravenous Dexmedetomidine, sevoflurane
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Yao Yusheng
Injection Site Irritation, Injection Site Bruising
Comparison of Subcutaneous Injection of Normal Saline and Bacteriostatic Saline
This is a randomized, double-blind, single-center clinical trial comparing normal saline and bacteriostatic saline subcutaneous injection within a single subject.
- Conditions
- Injection Site Irritation, Injection Site Bruising, Injection Site Discomfort, Benzoic Acid Adverse Reaction
- Trial name
- NCT05109000
- Testing
- Sodium Chloride 0.9% Inj, Bacteriostatic Sodium Chloride 0.9 % INJECTION VIAL (ML)
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Jeffrey Alan Klein, MD
Sedative Adverse Reaction
Effect of Sedation on Pulmonary Aeration in Children
Pediatric sedation is an anesthesiological technique with a good safety profile, but various complications might ensure, especially from the respiratory point of view.
- Trial name
- LunSed (NCT03392012)
- Where
- Italy
- Volunteers
- 180 people
- Sponsor
- IRCCS San Raffaele
Pain, Postoperative, Agitation States as Acute Reaction to Exceptional Stress
Gabapentin as Preanesthetic Medication to Fast Procedures in Pediatric´s Oncology
This study is a clinical trial, prospective, randomized and double-blinded. Placebo, Gabapentin syrup at 15 mg/kg, and Gabapentin syrup at 30 mg/kg were administered to reduce agitation before and after in children submitted…
- Conditions
- Pain, Postoperative, Agitation States as Acute Reaction to Exceptional Stress, Anesthesia, Vomiting
- Trial name
- NCT03681574
- Testing
- GABA 15mg/kg Group, GABA 30mg/kg Group
- Where
- Brazil
- Volunteers
- 135 people
- Sponsor
- Hospital Infantil Albert Sabin
Anesthesia; Reaction, Pain
Anesthetic Efficacy of Gow-Gates Versus Conventional Inferior Alveolar Nerve Block Techniques
The purpose of this study is to determine whether Gow Gates block injection is more effective than conventional alveolar nerve block in anesthetising mandibular molars with acute pulpitis.
- Trial name
- NCT01329874
- Testing
- Type of block injection
- Where
- Iran
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mashhad University of Medical Sciences
Pain, Postoperative, Adverse Reaction to Epidural Anesthesia
Pediatric Caudal Anesthesia Block. And Pain Control
Caudal epidural block CEB is the most commonly performed neuraxial block to provide effective pain relief and analgesia in patients undergoing infra-umbilical pediatric surgery.
- Conditions
- Pain, Postoperative, Adverse Reaction to Epidural Anesthesia, Anesthesia, Caudal
- Trial name
- CEB (NCT05581940)
- Testing
- Group A Caudal Epidural Anesthesia with bupivacaine 0.25% and group B with opioid intervenors
- Where
- Bahrain
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Salmaniya Medical Complex
Anesthesia, Anesthesia; Adverse Effect
EEG-guided Propofol Sedation Versus Standard Care for Oesophagogastroduodenoscopy and Colonoscopy in Children
The goal of this clinical trial is to compare electroencephalogram (EEG) guided propofol sedation versus standard care in paediatric patients aged 6-16 undergoing oesophagogastroduodenoscopy and colonoscopy.
- Conditions
- Anesthesia, Anesthesia; Adverse Effect, Anesthesia Emergence Delirium, Sedation Complication
- Trial name
- EPOC (NCT06225037)
- Testing
- Sedline EEG monitoring, Sedline EEG with output concealed
- Where
- Singapore
- Volunteers
- 50 people
- Sponsor
- KK Women's and Children's Hospital
Fentanyl Adverse Reaction, Caudal Anesthesia
Fast Tracking Impact on Fentanyl Consumption and Parents Satisfaction
The investigators are measuring fentanyl consumption in micrograms used during anesthesia for patients on fast track congenital cardiac surgeries
- Trial name
- NCT04376541
- Testing
- Fentanyl
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Propofol, Ketamine
Propofol-Ketamine Versus Sevoflurane for Laryngeal Mask Anesthesia in Pediatric Cardiac Catheterization
Children undergoing cardiac catheterization will be given anesthesia using either a combination of propofol and ketamine or sevoflurane gas. The time taken to fall asleep will be recorded.
- Conditions
- Propofol, Ketamine, General Anesthetic Drug Adverse Reaction
- Trial name
- NCT07907796
- Testing
- Ketamine-Propofol, Sevoflurane
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- Rawalpindi Institute of Cardiology
Anesthesia, Anesthesia; Reaction
Individual Cerebral Hemodynamic Oxygenation Relationships
This is a randomized controlled trial in patients who require clinical anesthesia. The main purpose of this study is to understand whether there are differences in the cerebral blood flow, and oxygen metabolism affected by two…
- Trial name
- ICHOR (NCT04435834)
- Testing
- Propofol or Sevoflurane
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Matthew Borzage
Anesthesia; Reaction, Anesthesia
Individual Cerebral Hemodynamic Oxygenation Relationships - ICHOR 4
The goal of this clinical trial is to understand whether there are differences in the cerebral blood flow, and oxygen metabolism affected by two types of anesthesia: Propofol or Dexmedetomidine.
- Trial name
- ICHOR (NCT07103616)
- Testing
- Randomization of Propofol or Dexmedetomidine
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Cesarean Section Complications, Postpartum Hemorrhage
Perioperative Outcomes of Postpartum Hemorrhage in Patients Undergoing Cesarean Delivery
Postpartum haemorrhage is the common cause of maternal death worldwide. The primary purpose of this study is to identify the maternal outcomes after PPH.
- Conditions
- Cesarean Section Complications, Postpartum Hemorrhage, Anesthesia Complication, Blood Transfusion Complication
- Trial name
- NCT04833556
- Where
- Thailand
- Volunteers
- 649 people
- Sponsor
- Mahidol University
Tonsillitis, Post-operative Nausea and Vomiting (PONV)
Opioid Sparing Anesthesia Care for Pediatric Patients Having Tonsil Surgery
This is a prospective, randomized, controlled, non-inferiority study of patients undergoing tonsil surgeries at Boston Children's Hospital Waltham.
- Conditions
- Tonsillitis, Post-operative Nausea and Vomiting (PONV), Emergence Delirium, Opioid Analgesic Adverse Reaction
- Trial name
- NCT06326983
- Testing
- Dexmedetomidine, Acetaminophen, Ketorolac
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Boston Children's Hospital
General Anesthetic Drug Allergy
The Clinical Study on Pseudo-allergic Reaction to Anesthetic Drugs During General Anesthesia
Perioperative anaphylactic reactions are immediate, hypersensitive reactions that are potentially life-threatening resulting from a sudden release of mediators from mast cells and basophiles.
- Trial name
- NCT03157180
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Central South University
Analgesic Adverse Reaction
Psoas Compartment Block (PCB) Versus L.A Infiltration and Remifentanil Infusion During EVAR
Endovascular aneurysm repair (EVAR) was introduced in 1990 for the first time as a minimally invasive procedure instead of the conventional open surgical repair, with the aim to decrease morbidity and mortality .
- Trial name
- NCT03443518
- Testing
- Psoas Compartment Block (PCB), Local Anesthesia infiltration, Normal saline 0.9% IV infusion
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 30 people
- Sponsor
- Dr. Erfan and Bagedo General Hospital
Anesthesia; Reaction, Children, Only
Effect of Anesthesia Induction on Cerebral Hemodynamic in Children
General anesthesia induces hemodynamic changes, notably a reduction of arterial blood pressure going up to 30%, that may impact cerebral perfusion and oxygenation.The purpose of this study is to assess the impact of anesthesia on…
- Trial name
- PEDICACHE (NCT04581213)
- Testing
- General anesthesia
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- St. Justine's Hospital
Opioid Analgesic Adverse Reaction
Cardiovascular Protection Conservative Effects of Esketamine Versus µ-opioid Receptor Agonists in General Anesthesia
Pain is 'a double-edged sword', disturbing daily life of the sufferers and activating the intrinsic protective mechanisms. Transient receptor potential vanilloid 1 (TRPV1), play such role as 'a double agent', transmitting the…
- Trial name
- NCT04553536
- Testing
- Esketamine, Sulfentanil or/and Remifentanil
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Second Hospital of Shanxi Medical University
Magnetic Resonance Imaging Contrast Media Adverse Reaction, Sedation Complication
Non-operating Room Anesthesia Experiences in Pediatric Magnetic Resonance Imaging Cases
In recent years, out patient anesthesia applications have been increasing for diagnostic and interventional procedures for pediatric patients.
- Trial name
- NCT05423821
- Testing
- Anesthesia efficacy in patients undergoing MRI
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Yunus Emre
Pain
Influence of Depth of Anesthesia on Pupillary Reactivity to a Standardized Stimulus
A standardized tetanic stimulation is applied to patients under propofol-remifentanil TCI, in a cross-over fashion, at two different levels of anesthesia monitored by the BIS: BIS 25 and BIS 55.
- Trial name
- NCT02595476
- Testing
- Remifentanil, propofol, TCI
- Where
- France
- Volunteers
- 12 people
- Sponsor
- Hôpital Armand Trousseau