Clinical trials: Anesthesia Effectiveness
Pain, Dental Anxiety
Effectiveness of Aromatherapy and Digital Anesthesia in Managing Dental Anxiety and Pain in Children
The goal of this clinical study is to learn whether aromatherapy and digital anesthesia are effective in reducing dental anxiety and pain during tooth extraction in children.
- Conditions
- Pain, Dental Anxiety, Tooth Extraction
- Trial name
- NCT07547371
- Testing
- Traditional Local Anesthesia (Conventional Syringe), Aromatherapy (Lavender or Orange Essential Oil), Digital Local Anesthesia (SleeperOne 5)
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Arzu Pınar Erdem
Depressive Disorder
Effects of Ciprofol Anesthesia on Learning and Memory Function and Antidepressant Effects of ECT in Depressive Patients
In this clinical study, propofol was used as the positive control, and a randomized controlled trial design was used to observe the effects of ciprofol anesthesia on learning and memory function and antidepressant efficacy in…
- Trial name
- NCT05266560
- Testing
- ciprofol, Propofol
- Volunteers
- 390 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Pulpitis
Buffered Versus Conventional Local Anesthesia for Pain and Anxiety Reduction in School-Aged Children With Pulpitis
The objective of this clinical trial is to evaluate whether buffered local anesthesia is more effective than conventional local anesthesia in reducing pain responses in school-aged children requiring dental treatment for…
- Trial name
- NCT07638254
- Testing
- Buffered Lidocaine with Epinephrine, idocaine with Epinephrine (Conventional)
- Where
- Mexico
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de San Luis Potosí
Other Acute Postoperative Pain
Paracetamol Versus Dipyrone After Pediatric Lower Abdominal Surgery in Children With Spinal Anesthesia
We conducted a prospective, randomized double-blind study to compare the effectiveness of intravenous paracetamol and dipyrone for preventing pain during early postoperative period in school-age children undergoing lower…
- Trial name
- NCT01858402
- Testing
- Paracetamol, Dipyrone
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Baskent University
Postoperative Pain
Caudal Block for Inguinal Hernioplasty in Children
This is a prospective, randomized, controlled clinical study designed to determine the effectiveness of caudal block combined with general anesthesia in providing intra- and postoperative analgesia, and its effect on hemodynamic…
- Trial name
- NCT05958589
- Testing
- Caudal block with levobupivacaine, General anesthesia, Inguinal hernioplasty
- Where
- Serbia
- Volunteers
- 70 people
- Sponsor
- University of Novi Sad
Airway Management
Compare the Efficacy of Different Laryngeal Mask Size Selection Methods in General Anesthesia in Children
The laryngeal mask is widely used in general anesthesia in children. Selection of an appropriately sized laryngeal mask airway (LMA) is critical to ensure safe and effective use of the device.
- Trial name
- NCT03845998
- Testing
- use the three-finger method, use the weight-related method
- Where
- China
- Volunteers
- 392 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Pediatric Anesthesia, Airway Management
Effective Dose of Alfentanil Combined With Propofol for Laryngeal Mask Airway Insertion in Children
This study uses a prospective, up-and-down sequential allocation method to determine the median effective dose (ED50) and 95% effective dose (ED95) of alfentanil combined with propofol for successful laryngeal mask airway (LMA)…
- Conditions
- Pediatric Anesthesia, Airway Management, General Anesthesia, LMA
- Trial name
- NCT07581665
- Testing
- Alfentanil
- Where
- China
- Volunteers
- 23 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Anesthesia, Local
Effectiveness of Buccal Infiltration During Vital Pulpotomy After Administering Two Analgesic Premedications
This Randomized study was designed to assess and compare the effect of two analgesic premedications (Ibuprofen BP 100 mg/5 ml and Paracetamol 200 mg/5ml.) on the anesthetic efficacy of buccal infiltration in vital pulpotomy of…
- Trial name
- NCT03423329
- Testing
- Brufen, Cital
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pain, Post Operative, Regional Anesthesia
Pain Reduction in Maxillomandibular Surgery Using Maxillary and Mandibular Nerve Blocks
Maxillo-mandibular osteotomy is a painful surgery which requires mostly opioids use. Recent studies on maxillary and mandibular nerve blocks have suggested benefit in maxillo-facial surgery but have been poorly investigated in…
- Trial name
- ECHOMAX (NCT05351151)
- Testing
- bilateral ultra-sound guided maxillary and mandibular nerve blocks, Infiltration of Lidocaine 1%
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Toulouse
Emergence Agitation
Propofol Versus Dexmedetomidine Effect on Prevention Emergence Agitation
The goal of this clinical trial is to compare Propofol versus Dexmedetomidine in children undergoing squint surgery. The main question it aims to answer is: Which drug is more effective in preventing the appearance of Emergence…
- Trial name
- NCT06312618
- Testing
- Propofol, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Sacral Erector Spinae Plane Block, Pediatric Regional Anesthesia
Sacral Erector Spinae Plane Block Versus Penile Block For Analgesia In Pediatric Circumcision
Circumcision is one of the most frequently performed surgical procedures in childhood and is associated with significant postoperative pain.
- Conditions
- Sacral Erector Spinae Plane Block, Pediatric Regional Anesthesia, Regional Anaesthesia
- Trial name
- NCT07321717
- Testing
- Sacral Erector Spinae Plane Block, Penile Nerve Block (PNB)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University - Cerrahpasa
Local Anesthesia
Effectiveness of Sodium Bicarbonate Buffered Anaesthetic Solution on Pain During Injection
This study will test the effectiveness of addition of Sodium Bicarbonate as a buffering agent to the anaesthetic solution on minimizing the pain of injection and increasing the onset time and potency of the anaesthetic solution…
- Trial name
- NCT05473819
- Testing
- Buffered Local Anesthesia, Conventional Unbuffered Local Anesthesia
- Where
- Egypt
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Hemodynamic Stability, Post Operative Pain
Comparative Efficacy & Safety of Dexmedetomidine vs Tramadol in Paeds Hernioraphy. A Caudal Anaesthesia Approach
Among the postoperative adverse effects, pain has significant importance. Caudal block is a common technique for pediatric analgesia for infraumbilical surgeries.
- Conditions
- Hemodynamic Stability, Post Operative Pain, Inguinal Hernia Repair
- Trial name
- NCT06735443
- Testing
- Bupivacaine with Dexmetedomidine, Bupivacaine with Tramadol
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sahiwal medical college sahiwal
Anesthesia, Dental
Study of NV-101 for Efficacy, Pharmacodynamics, and Safety in Dental Patients Undergoing Maxillary Procedures
This Phase 3 clinical study is designed as a multicenter, randomized, blinded, controlled study to evaluate the efficacy, pharmacodynamics, and safety of NV-101 administered as a submucosal injection following completion of a…
- Trial name
- NCT00309335
- Testing
- Phentolamine Mesylate (NV-101)
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Novalar Pharmaceuticals, Inc.
Elective Surgery of Short Duration (Less Than 2 hr) Undergoing General Anesthesia Using Supraglottic Airway
The Comparison of the Clinical Efficacy Between I-gel and LMA-Supreme, the Two Most Recently Developed Supraglottic Airway Devices, in Infants
Although the safety and efficacy of the I gel in children has been shown in several large observational studies, There is no study about comparison of the clinical efficacy between I-gel and LMA-Supreme , in particular sizes 1…
- Trial name
- NCT01863316
- Testing
- I gel, LMA Supreme
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Yonsei University
Restorative Dental Treatment by Buccal Infiltration Anaesthesia
Clinical Evaluation of Anaesthetic Efficacy of 4% Articaine Buccal Infiltration Versus Inferior Alveolar Nerve Block
Clinical evaluation of anaesthetic efficacy of 4% articaine buccal infiltration versus inferior alveolar nerve block during restorative dental treatment in mandibular first permanent molars
- Trial name
- NCT06353815
- Testing
- 4% articaine infiltration
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Cairo University
Anesthesia, Supraglottic Airway Efficiency
Clinical Efficacy Evaluation of Supraglottic Airway Device SafeLM™ in Paediatric Population
The goal of this interventional study is to evaluate the clinical efficacy of SafeLM™, a video laryngeal mask airway device in paediatric population. The main questions it aims to answer are: 1.
- Conditions
- Anesthesia, Supraglottic Airway Efficiency, Paediatric Airway Management
- Trial name
- NCT07266389
- Testing
- SafeLM™ as the airway management device during general anaesthesia
- Where
- 2 sites in Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Dental Anxiety, Pain
Effectiveness of Hand/Eyes/Mouth Behavior Management Technique During Local Anesthesia in Preschool Children
This will be a randomized, controlled, parallel-group clinical trial. The aim of this studio will be to evaluate the effectiveness of "Hands/Eyes/mouth" behavior management technique versus a conventional technique (covering the…
- Conditions
- Dental Anxiety, Pain, Infant Behavior, Heart Rate and Rhythm Disorders
- Trial name
- NCT02591797
- Testing
- inferior alveolar and lingual nerve block procedure
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- Cardenal Herrera University
Orchiopexy
Comparison of Analgesic Efficacy of Fascia Transversalis Plan Block and Caudal Epidural Block in Pediatric Patients Undergoing Orchiopexy
Orchiopexy is a surgery with a high frequency in the pediatric population. The use of regional anesthesia techniques has become widespread and its importance has increased in order to provide more effective and prolonged…
- Trial name
- NCT07006844
- Volunteers
- 60 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Dental Anesthesia, Sweet Taste Perception
Efficacy of Pre-cooling and Sweet-tasting Solution on Pain Related to Local Anesthesia Injection in Children
The study aims to determine whether pre-cooling and sweet-tasting solutions, alone or combined with topical anesthesia, provide better pain control during dental local anesthesia in children.
- Conditions
- Dental Anesthesia, Sweet Taste Perception, Pain and Anxiety, Behavioral Management
- Trial name
- NCT07835191
- Testing
- Dental anesthesia
- Where
- Egypt
- Volunteers
- 224 people
- Sponsor
- British University In Egypt