Clinical trials: Anesthesia Induction
Children Under General Anesthesia
Study on Changes of Pulse Oximeter Plethysmographic Amplitude Induced by Respiration in Pediatric Patients
The purpose of this study is to evaluate the variations of respiratory changes in pulse oximeter plethysmographic amplitude (delta POP) according to different contact forces between finger and sensor of pulse oximeter.
- Trial name
- NCT02940938
- Testing
- Applying pulse oximeter sensor
- Where
- South Korea
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Transversus Abdominis Plane (TAP) Block
IV Sedation Plus TAP Block for Placement of Percutaneous Endoscopic Gastrostomy Tube
Objective: To determine the effectiveness and safety of IV sedation combined with ultrasound-guided, left side transversus abdominis plane (TAP) block versus combination with local anesthetic (LA) infiltration for Percutaneous…
- Trial name
- NCT04878926
- Testing
- IV midazolam and propofol-based sedation combined with ultrasound-guided, left side TAP block, IV midazolam and propofol-based sedation with Local Anesthetic infiltration
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Damanhour Teaching Hospital
Anesthesia
Effect of a Modified Propofol Preparation on Injection Pain During Induction of Anesthesia in Children
The purpose of the study is to determine wether a modified propofol preparation shows any effect on the incidence of injection pain in children undergoing elective surgery under general anesthesia.
- Trial name
- NCT00287560
- Testing
- propofol (drug)
- Volunteers
- 64 people
- Sponsor
- B. Braun Melsungen AG
Pediatric
Effects of Chloral Hydrate on Induction, Maintenance, and Recovery From Sevoflurane Anesthesia in Day-case Pediatric Surgery
Effects of Choral Hydrate on Induction, Maintenance, and Recovery from Sevoflurane Anesthesia in Day-case Pediatric Surgery
- Trial name
- NCT01149226
- Testing
- chloral hydrate
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Yonsei University
Anesthesia Complication
Effect of Midazolam Premedication on Mask Ventilation Difficulty
Mask ventilation has great importance during anesthesia induction because it is the only way to oxygenate patients who have lost consciousness and spontaneous breathing.
- Trial name
- NCT05368441
- Testing
- Midazolam, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Karaman Training and Research Hospital
Pain, Postoperative, Agitation States as Acute Reaction to Exceptional Stress
Gabapentin as Preanesthetic Medication to Fast Procedures in Pediatric´s Oncology
This study is a clinical trial, prospective, randomized and double-blinded. Placebo, Gabapentin syrup at 15 mg/kg, and Gabapentin syrup at 30 mg/kg were administered to reduce agitation before and after in children submitted…
- Conditions
- Pain, Postoperative, Agitation States as Acute Reaction to Exceptional Stress, Anesthesia, Vomiting
- Trial name
- NCT03681574
- Testing
- GABA 15mg/kg Group, GABA 30mg/kg Group
- Where
- Brazil
- Volunteers
- 135 people
- Sponsor
- Hospital Infantil Albert Sabin
Intravenous Cannulation, Sevoflurane Induction
Intravenous Cannulation In Children During Sevoflurane Induction
The early placement of an intravenous (iv) line in children anesthetized with halothane has been shown safe and acceptable compared with later placement. However, there's not well known with sevoflurane use (2).
- Conditions
- Intravenous Cannulation, Sevoflurane Induction, Child
- Trial name
- NCT03851692
- Testing
- Intravenous Cannulation (iv placement)
- Volunteers
- 90 people
- Sponsor
- University Hospital Fattouma Bourguiba
Intravenous Access, Pediatric Patient
Intravenous Access Time in Pediatric Patients
In pediatric patients with no vascular access, anesthesia induction is usually achieved with sevoflurane. The aim of investigators to evaluate the optimum intravenous access time and the corresponding bispectral index (BIS) value…
- Trial name
- NCT04190407
- Testing
- Intravenous access
- Volunteers
- 84 people
- Sponsor
- Istanbul Medeniyet University
Anesthesia and Neurotoxicity
Association Between Anesthetic Drugs for General Anesthesia and Postoperative Intelligence/behavioral Assessment Results in Children
In this study, we compared the results of the intelligence and behavioral test performed after surgery between the group using sevoflurane and the group receiving dexmedetomidine and remifentanil, in Korean children under 2 years…
- Trial name
- NCT04364945
- Testing
- dexmedetomidine, remifentanil, Sevoflurane
- Where
- South Korea
- Volunteers
- 400 people
- Sponsor
- Seoul National University Hospital
Oxygen Deficiency
High-flow Nasal Cannula for Pediatric Anesthetic Induction
Endotracheal intubation in infants often involves more than one attempt, and oxygen desaturation is common. It is unclear whether nasal high-flow therapy, which extends the time to desaturation during elective intubation in…
- Trial name
- NCT05578131
- Testing
- high flow nasal oxygen, face mask
- Where
- South Korea
- Volunteers
- 132 people
- Sponsor
- Seoul National University Hospital
Negative Behaviour Change
Pilot Study: Intraoperative Clonidine and Postoperative Behaviour
Children who are upset during induction of general anaesthesia are frequently distressed postoperatively and are more likely to demonstrate negative behaviour changes.
- Trial name
- NCT02324413
- Testing
- Clonidine
- Where
- United Kingdom
- Volunteers
- 45 people
- Sponsor
- Richard Beringer
Agitation
ED50 of Dexmedetomidine to Prevent Emergence Agitation in Children
There are several recommended doses of dexmedetomidine for prevention of emergence agitation in children. In this study, the investigators examine ED50 in prevention of emergence agitation after tonsillectomy or adenoidectomy in…
- Trial name
- NCT01374737
- Testing
- Dexmedetomidine
- Where
- South Korea
- Volunteers
- 25 people
- Sponsor
- Seoul National University Hospital
Perioperative Anxiety, Preanesthetic Medication
Handheld-multimedia Versus Oral Midazolam in Pediatric on Perioperative Anxiety
The first goal of this study is to compare the efficacy and safety between anxiolysis by multimedia-distraction with an IPAD versus anxiolysis by premedication with midazolam prior to the induction.
- Conditions
- Perioperative Anxiety, Preanesthetic Medication, Inhalation Anesthesia, Ambulatory Surgery
- Trial name
- NCT04273035
- Testing
- Midazolam oral solution, IPAD
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- Universitair Ziekenhuis Brussel
Airway Obstruction
Effectiveness Of Apneic Oxygenation During Induction Of General Anesthesia In Children
During general anesthesia, the administration of anesthetics and muscle relaxants induces apnea, wherein spontaneous breathing ceases .
- Trial name
- NCT06742476
- Testing
- nasal cannula
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Fayoum University Hospital
Induction of Anesthesia
Diversion Device With Breath Control
The experience for many children who need to undergo anesthesia induction by breathing anesthetic vapors in the operating room is frightening to the child.
- Trial name
- NCT04208984
- Testing
- Study, Music Video
- Where
- United States
- Sponsor
- University of Utah
Neuromuscular Blockade
Comparing Reversal With Neostigmine and Sugammadex in Paediatric
A reversal agent is commonly given to improve neuromuscular function after intra-operative administration of non-depolarizing neuromuscular blocking agents.
- Trial name
- JS (NCT03137290)
- Testing
- Neostigmine, Sugammadex Sodium
- Where
- Malaysia
- Volunteers
- 80 people
- Sponsor
- Universiti Sains Malaysia
Anesthesia; Reaction, Children, Only
Effect of Anesthesia Induction on Cerebral Hemodynamic in Children
General anesthesia induces hemodynamic changes, notably a reduction of arterial blood pressure going up to 30%, that may impact cerebral perfusion and oxygenation.The purpose of this study is to assess the impact of anesthesia on…
- Trial name
- PEDICACHE (NCT04581213)
- Testing
- General anesthesia
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- St. Justine's Hospital
Atelectasis
Effect of Spontaneous Breathing on Atelectasis During Induction of General Anesthesia in Patients in Infants
spontaneous breathing on occurrence of atelectsis in infants
- Trial name
- NCT03739697
- Testing
- spontaneous breathing
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul National University Hospital
Anesthesia, Neurotoxicity
A Study to Compare the Long-term Outcomes After Two Different Anaesthetics
There is considerable evidence that most general anaesthetics modulate brain development in animal studies. The impact is greater with longer durations of exposure and in younger animals.
- Conditions
- Anesthesia, Neurotoxicity, Child Development
- Trial name
- TREX (NCT03089905)
- Testing
- Sevoflurane, Remifentanil, Dexmedetomidine
- Where
- 21 sites in United States, Australia and 2 more
- Volunteers
- 450 people
- Sponsor
- Murdoch Childrens Research Institute
Anesthesia Intubation Complication
Propofol for Pediatric Tracheal Intubation With Deep Anesthesia During Sevoflurane Induction
The purpose of this study is to determine the amount of propofol required to achieve 50% of patients obtaining a perfect ("excellent") intubation score of 5 on the Steyn modification of the Helbo-Hansen Intubation Score, when…
- Trial name
- NCT01150838
- Testing
- propofol
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- University of Virginia