Clinical trials: Anesthesia Induction
Surgery
Low Dose IV Dexamethasone in Prolonging Caudal Anesthesia in Children Undergoing Genitourinary Surgery
Caudal injection of local anesthetic is a neuraxial technique routinely performed on young children for postoperative analgesia after lower abdominal and lower extremity surgical procedures.
- Trial name
- NCT02436265
- Testing
- Dexamethasone, Ropivacaine
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Indiana University
Tooth Extractions
Comparison of Sufentanil and Remifentanil Infusion During General Anaesthesia for Removal of Wisdom Teeth in Ambulatory Surgery
Wisdom teeth removal under general anaesthesia is usually suitable for ambulatory surgery. The choice of opioid in dental day surgery is based on the need for a rapid and full recovery, as well as less morphine administration.
- Trial name
- SUF-REM-DDS (NCT01139671)
- Testing
- Remifentanil
- Where
- France
- Volunteers
- 18 people
- Sponsor
- University Hospital, Clermont-Ferrand
Emergence Agitation
Sevoflurane Induced Emergence Agitation
Investigators evaluated the effect of intranasal ketamine or alfentanil addition to oral midazolam for prevention of emergence agitation.Seventy-eight, 1-8 year-old children, undergoing urological surgery with sevoflurane…
- Trial name
- NCT02022488
- Testing
- midazolam, alfentanil, ketamine
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Yeditepe University Hospital
Scoliosis, Spinal Deformity
Bilateral Bi-level Erector Spine Plane Block as a Component of General Anesthesia in Surgical Correction of Spinal Deformations
Improving the anesthesiology management for surgical correction of spinal deformations with introducing the diagnostic methods and treatment strategy of acute pain, preventing the evolution of chronic pain.
- Conditions
- Scoliosis, Spinal Deformity, Acute Pain, Chronic Pain
- Trial name
- BBESPB (NCT04697498)
- Testing
- Bilateral bi-level Erector spine plane block, General anaesthesia
- Where
- Ukraine
- Volunteers
- 150 people
- Sponsor
- Lviv National Medical University
Gastric Insufflation
Efficacy of Mechanical Ventilation With Facial Mask to Reduce Gastric Insufflation
The purpose of this study is to determine whether mechanical ventilation with facial mask during induction anesthesia in the population of 1month to 14years is associated with less risk of gastric insufflations as compared with…
- Trial name
- NCT01652924
- Testing
- Mechanical ventilation with facial mask, Manual ventilation with facial mask
- Where
- Colombia
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Universidad de Antioquia
Anesthesia
Dexmetomidine in Children Undergoing General Anaesthesia
The effects of dexmedetomidine on the onset of both the general anaesthesia induction and the neuromuscular blockade in children of school age will be investigated.
- Trial name
- NCT03923075
- Testing
- Dexmedetomidine, 0.9% saline
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Attikon Hospital
General Anesthetic
HSK3486 (Cipepofol) Injectable Emulsion for Induction of General Anesthesia in Pediatric Subjects Undergoing Elective Surgery
This multicenter, randomized, double-blinded, propofol-controlled Phase 3b study enrolls pediatric subjects aged 3-17 years undergoing elective surgery with endotracheal intubation.
- Trial name
- NCT07510945
- Testing
- HSK3486, propofol
- Volunteers
- 400 people
- Sponsor
- Haisco Pharmaceutical Group Co., Ltd.
Pediatric Population, Preoperative Anxiety
Comparing the Effectiveness of Virtual Reality in Paediatric Patients
To the best of our knowledge,the investigators found only a study using VR in reducing preoperative anxiety in paediatric population.
- Trial name
- NCT06044753
- Testing
- Virtual Reality Headset
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
Anesthesia Brain Monitor, Anesthesia
Elucidating the Neural Correlates of Anesthesia-induced Unconsciousness in Neonates
This study will try to elucidate the neural responses of neonatal patients to surgery-level propofol infusions during induction and maintenance of anesthesia.
- Conditions
- Anesthesia Brain Monitor, Anesthesia, Neonatal Surgery
- Trial name
- NeoNCC (NCT07601854)
- Volunteers
- 64 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Craniosynostosis, Anesthesia
Influence of General Anesthesia on the Dynamic Changes in Brain Damage Markers During and After Craniosynostosis Operations in Infancy
The issue of anesthetics neurotoxicity is one of the most discussed topics in pediatric anesthesiology, thus it opens the question of the safety of commonly used anesthetics in the pediatric patient.
- Trial name
- TAnBrainDam (NCT05911139)
- Where
- Slovakia
- Volunteers
- 45 people
- Sponsor
- Comenius University
Anesthesia, General, Neuromuscular Blockade
Pharmacokinetic-pharmacodynamic Analysis of Sugammadex in Children
This study administers sugammadex sodium to pediatric patients under general anesthesia with rocuronium. Pharmacokinetic and pharmacodynamic analysis are performed based on plasma concentration of sugammadex sodium and monitoring…
- Trial name
- NCT03943888
- Testing
- Sugammadex Injection 2mg/kg, Sugammadex Injection 4mg/kg, Sugammadex Injection 8mg/kg
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul National University Hospital
Anxiety
Audiovisual Interactive Games to Alleviate Pediatric Perioperative Anxiety
Pediatric anxiety upon induction of anesthesia is widely prevalent and can lead to negative patient psychological impact and hindrance to induction of anesthesia.
- Trial name
- NCT06111742
- Testing
- Bedside Entertainment and Relaxation Theater (BERT)
- Where
- United States
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- Yale University
Emergence Delirium, Postopertive Delirium
Magnesium Sulphate and Sevoflurane Induced Emergence Agitation in Children
Rationale: Pediatric Adenotonsillectomy is a common procedure of brief performed on a day-case basis, in which rapid recovery with safe airway after extubation is crucial.
- Conditions
- Emergence Delirium, Postopertive Delirium, Emergence Agitation in Children
- Trial name
- NCT01743144
- Testing
- Magnesium Sulfate, normal saline
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Cairo University
Preeclampsia
Peripartum Anesthetic Management of Patients With Preeclampsia
The investigators will conduct a prospective, observational multicentral international study of perioperative management of patients with preeclampsia.
- Trial name
- NCT05237011
- Where
- Israel
- Volunteers
- 1,500 people
- Sponsor
- Shaare Zedek Medical Center
Movement After Intravenous Cannulation
Optimum Time for Intravenous Cannulation After Induction With Sevoflurane in Pediatric Patient
This study aimed to determinate effective dose 95 (ED95) intravenous cannulation in pediatric patient after induction of sevoflurane 8 vol%
- Trial name
- NCT04284579
- Testing
- IV cannula
- Where
- Indonesia
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Anxiety, Surgery
Virtual Parental Presence on Induction of Anesthesia vs Premedication With Midazolam
This multi-center, prospective, clinical trial targets recruiting children undergoing inhalational induction of anesthesia. The primary objective of this study is to assess the Modified Yale Preoperative Anxiety Scale during…
- Trial name
- NCT05834049
- Testing
- Virtual Parental Presence on Induction of Anesthesia, Midazolam
- Sponsor
- Stanford University
Emergencies, Anesthesia
Comparison of Three Pre-oxygenation Strategies
Study objective: Comparing the efficacy of three different preoxygenation strategies, i.e. non-rebreather face mask (NRM), bag-valve-mask (BVM) with and BVM without additional positive end-expiratory pressure (PEEP) in three…
- Trial name
- NCT06370689
- Testing
- Preoxygenation
- Where
- Italy
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Institute of Mountain Emergency Medicine
Continuous Positive Airway Pressure, Hypoxia
Positive Pressure at Induction of Anesthesia in Children
SCENARIO: Hypoxemia is one of the most common adverse events during the induction of general anesthesia and may culminate with more serious complications such as cardiac arrest and death.
- Conditions
- Continuous Positive Airway Pressure, Hypoxia, General Anesthesia
- Trial name
- NCT03432390
- Testing
- Continuous Positive Airway Pressure, Open system ventilation
- Where
- Brazil
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Transversus Abdominis Plane (TAP) Block, Wound Infiltration
Ultrasound-guided Transversus Abdominis Plane Block Versus Local Wound Infiltration (TAP_WI)
The goal of this clinical trial is to learn if transversus abdominis plane (TAP) block will reduce the cumulative opioid consumption compared to local wound infiltration (WI).
- Conditions
- Transversus Abdominis Plane (TAP) Block, Wound Infiltration, Pain Score (VAS), Opioid Analgesia
- Trial name
- TAP (NCT06627946)
- Testing
- TAP group
- Where
- Bhutan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Bhutan
Anesthesia Induced Atelectasis
Evaluation of the Effect of Lung Recruitment and Positive End- Expiratory Pressure (PEEP) on Anesthesia Induced Atelectasis Using Lung Ultrasound
Atelectasis is a side effect of general anesthesia which can be found in all types of interventions and patients of all ages.1-3 The reported incidence of anesthesia- induced atelectasis in children varies, ranging from 12 to 42%…
- Trial name
- NCT03069157
- Testing
- lung recruitment maneuver
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital