Clinical trials: Anesthetics, Inhalation
Anesthesia, General, Sevoflurane
Frequency Analysis of Raw EEG During Sevoflurane Anesthesia in Children Younger Than 2 Years Old
The purpose of this study is to analyze raw electroencephalogram in infants younger than 2 years old undergoing general anesthesia using sevoflurane.
- Conditions
- Anesthesia, General, Sevoflurane, Infant
- Trial name
- NCT05148065
- Testing
- BIS, PSi
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Sang-Hwan Ji
Mechanical Ventilation
Retrospective Study on Prolonged Sedation Effects With Inhaled Agents in PICU
The objective of the study is to evaluate the effects of halogenated gases on sedation and analgesia, to describe the tolerance and to determine the risk factors for failure, in pediatric intensive care patients during prolonged…
- Trial name
- RESPIRE (NCT05064592)
- Where
- 2 sites in France
- Volunteers
- 50 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Anesthesia, General, Electroencephalography
Anesthesia and EEG Discontinuity in Infants
This study is a randomized controlled trial to evaluate whether EEG-guided calibration of inhalation agents can reduce occurrence of EEG discontinuity in infants during general anesthesia.
- Conditions
- Anesthesia, General, Electroencephalography, Infant, Anesthesia, Inhalation
- Trial name
- NCT05906225
- Testing
- EEG guided anesthesia, Conventional anesthesia
- Where
- South Korea
- Volunteers
- 78 people
- Sponsor
- Seoul National University Hospital
Anesthetics, Inhalation, Neuromuscular Blockade
Effect of Rocuronium and Sugammadex Under Sevoflurane and Desflurane Anesthesia in Children
Sugammadex is the first selective relaxant binding agent approved to reverse certain non-depolarizing neuromuscular drugs in patients 2 years old and above.
- Conditions
- Anesthetics, Inhalation, Neuromuscular Blockade, Anesthesia, General
- Trial name
- NCT03795259
- Testing
- Rocuronium, Sugammadex
- Where
- Turkey (Türkiye)
- Volunteers
- 148 people
- Sponsor
- Istanbul University
Anesthetics, Inhalation
50% Effective Concentration of Sevoflurane for Immobility
Sevoflurane is as attractive inhalation agent fore deep sedation in children undergoing short invasive procedure because of lack of irritation to the respiratory tract, a pleasant odor and rapid clinical effect and recovery due…
- Trial name
- NCT03553446
- Testing
- children receiving sevoflurane
- Where
- South Korea
- Volunteers
- 23 people
- Sponsor
- Yeungnam University College of Medicine
Pulmonary Aspiration of Gastric Contents
Gastric Content After 6 vs 4 Hours of Preoperative Fasting in Children
The primary objective of the study is to compare the risk of increased stomach contents after tube feeding (Enteral feeding) 6 and 4 hours before anesthesia using antrum measured by ultrasound.
- Trial name
- ENGUS (NCT05695066)
- Testing
- Preoperative fasting instruction
- Where
- Sweden
- Volunteers
- 180 people
- Sponsor
- Uppsala University Hospital
Solid Tumor, Carcinoma
Propofol vs Sevo for Paediatric Tumor Surgery
Background: Retrospective studies and meta-analyses have shown a reduction in 5-year survival following inhalational based compared to propofol based total intravenous (TIVA) anaesthesia for cancer surgery.
- Conditions
- Solid Tumor, Carcinoma, Malignancy, Cancer
- Trial name
- NCT04475705
- Testing
- propofol, sevoflurane
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- Hong Kong Children's Hospital
Exposure to Environmental Pollution, Adverse Effect of Unspecified General Anesthetic
Anesthetic Gas Leakage in Children During Tonsillectomy: a Comparison of Cuffed and Uncuffed Tracheal Tubes
Fires and operating room pollution may occur when anesthesia gases leak into the oropharynx during airway surgery. Investigators sought to measure the concentrations of anesthetic gases that leak into the mouth of children…
- Trial name
- NCT02725164
- Testing
- oxygen concentration, nitrous oxide concentration, carbon dioxide concentration
- Volunteers
- 31 people
- Sponsor
- State University of New York at Buffalo
General Anesthesia, Children
Effects of Binaural Beats on Inhaled Anesthetic Requirements During General Anesthesia in Pediatric Patients
The hypothesis of this study is that continuously delivering binaural beats with a phase difference corresponding to the slow-delta frequency band during anesthesia in pediatric patients can clinically and significantly reduce…
- Trial name
- NCT06979206
- Testing
- Application of Binarual Beat
- Volunteers
- 68 people
- Sponsor
- Seoul National University Hospital
Anaesthesia, Intraocular Pressure
Effects Of Anaesthesia on Intraocular Pressure in Robotic Prostate Surgery
Robot-assisted surgery is now commonly used to treat prostate cancer. This type of surgery, called robot-assisted prostatectomy, helps doctors operate more precisely and allows patients to heal faster.
- Conditions
- Anaesthesia, Intraocular Pressure, Trendelenburg Position, Robot Assisted Laparoscopic Radical Prostatectomy
- Trial name
- NCT07033442
- Testing
- Sevoflurane (Volatile Anesthetic), Propofol 1%, Remifentanil 2 MG
- Volunteers
- 60 people
- Sponsor
- Ataturk Training and Research Hospital
Anesthesia
Reducing the Carbon Footprint Through Education on the Effects of Inhalation Anesthetics on Global Warming
Inhalation anesthetics, such as desflurane, are identified as contributors to global warming, with the European Union planning to ban desflurane in 2026 due to its impact.
- Trial name
- NCT06084039
- Where
- South Korea
- Volunteers
- 4,478 people
- Sponsor
- Pusan National University Yangsan Hospital
Dental Anxiety, Anxiety Disorder
Lavender Oil Inhalation Help to Overcome Dental Anxiety Among Children
The purpose of this study is to investigate the impact of lavender oil (Lavandula angustifolia) on anxiety, pain and vital signs (blood pressure, heart rate and saturation) among children planned to undergone surgical…
- Conditions
- Dental Anxiety, Anxiety Disorder, Aromatherapy
- Trial name
- NCT04115891
- Testing
- Anxiety scale, Pain scale - 1, Pain scale - 2
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Sedation
Effect & Safety of Inhaled Isoflurane vs IV Midazolam for Sedation in Mechanically Ventilated Children 3-17 Years Old
This is a study to compare safety and efficacy of inhaled isoflurane delivered by the AnaConDa-S (Anaesthetic Conserving Device (ACD)) versus intravenous midazolam for sedation in mechanically ventilated children admitted to an…
- Trial name
- IsoCOMFORT (NCT04684238)
- Testing
- Midazolam, Isoflurane
- Where
- 24 sites in France, Germany and 3 more
- Volunteers
- 94 people
- Sponsor
- Sedana Medical
Intensive Care Units, Pediatric, Anesthetics, Inhalation
Advancing Brain Outcomes in Pediatric Critically Ill Patients Sedated With Volatile AnEsthestic Agents
The goal of a pilot study is to test a study plan to see if it is appropriate for a larger study. This study plan is looking at whether the use of inhaled sedatives (medications that help people be calm and sleep) can reduce…
- Conditions
- Intensive Care Units, Pediatric, Anesthetics, Inhalation, Mechanically Ventilated, Critically Ill Children
- Trial name
- ABOVE (NCT05867472)
- Testing
- Isoflurane Inhalant Product
- Where
- 3 sites in Canada
- Volunteers
- 60 people
- Sponsor
- Sunnybrook Health Sciences Centre
General Anesthetics Toxicity, Postoperative Cognitive Dysfunction
The Influence of Electroacupuncture on Postoperative Agitation of Pediatrics Undergoing Sevoflurane General Anesthesia
Postoperative agitation is a common complication in pediatric anesthesia, with an incidence ranging from 10% to 80%. Common surgical procedures in children include tonsillectomy, adenoidectomy, insidious penis prolongation and…
- Conditions
- General Anesthetics Toxicity, Postoperative Cognitive Dysfunction, Electroacupuncture
- Trial name
- DZDXEQFWQMSHZD (NCT05924854)
- Testing
- electroacupuncture
- Where
- China
- Volunteers
- 80 people
- Sponsor
- The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine
Anesthesia
Comparison of Minimal Fresh Gas Requirements of Baby EAR and Jackson Rees Anesthetic Circuit
The investigators invented the baby enclosed afferent reservoir anesthesia circuit (Baby EAR) which could be used safely in children between 5 and 20 kg, using a fresh gas flow of 2.5 and 3 L/min in the spontaneous breathing and…
- Trial name
- NCT02167269
- Testing
- Baby EAR
- Where
- Thailand
- Volunteers
- 20 people
- Sponsor
- Khon Kaen University
Sleep Disordered Breathing, Drug Induced Sleep Disorder
DISE in Pediatric Sleep Disordered Breathing
Adenotonsillar hypertrophy is the most common reason for children to have sleep disordered breathing (SDB). Even though adenotonsillectomy improves sleep apnea in children, 20-40% of children will still have persistent SDB.
- Trial name
- NCT06756971
- Testing
- Propofol, Dexmedetomidine
- Sponsor
- University of Iowa
Catheterization
Intravenous Cannulation In Children During Sevoflurane Induction
This interventional simple-blind,randomized trial has included 90 children of American Society of Anesthesiologist (ASA) physical status I or II aged between 1 to 12 years of either sex, scheduled for for outpatient minor surgery…
- Trial name
- NCT03254303
- Testing
- Difficulty of catheterization in group 60 s, Difficulty of catheterization in group 90 s, Difficulty of catheterization in group 120 s
- Volunteers
- 90 people
- Sponsor
- Leila mansali stambouli
Aromatherapy
The Efficacy of Sweet Orange Oil Inhalation in Management of Dental Anxiety and Pain
Aim of the study To evaluate the effectiveness of sweet orange oil inhalation in reducing dental anxiety and pain in children undergoing local anaesthetic administration.
- Trial name
- NCT06063512
- Testing
- sweet orange oil inhalation
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Cairo University
Child, Only, Inhalation; Vapor
Cerebral and Peripheral Near Infrared Spectroscopy Monitoring in Low and High Flow Anaesthesia in Pediatric
To investigate the effects of non-invasive cerebral and peripheral NIRS monitoring and low and high flow sevoflurane anaesthesia on cerebral and peripheral NIRS in paediatric patients.
- Conditions
- Child, Only, Inhalation; Vapor, Anesthesia, Cerebral Oxygenation
- Trial name
- NCT06320743
- Testing
- NIRS ,Ventilation parameters, Oxygen concentration
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Ankara City Hospital Bilkent