Clinical trials: Aneurysmal Subarachnoid Hemorrhage
Subarachnoid Aneurysm Hemorrhage, Microsurgery
Structural and Clinical Predictors of Cognitive Impairment After Surgical Treatment for Ruptured Cerebral Aneurysms
This study investigates the clinical and structural predictors of long-term cognitive impairment in patients who underwent microsurgical clipping for aneurysmal subarachnoid hemorrhage.
- Conditions
- Subarachnoid Aneurysm Hemorrhage, Microsurgery, Cognitive Impairment
- Trial name
- SCOPE-aSAH (NCT07723131)
- Where
- Brazil
- Volunteers
- 150 people
- Sponsor
- University of Campinas, Brazil
Aneurysmal Subarachnoid Hemorrhage
Long-term Prognosis of Emergency Aneurysmal Subarachnoid Hemorrhage
Rupture of intracranial aneurysms can lead to extensive subarachnoid hemorrhage (SAH), a potentially fatal neurological emergency with mortality rates ranging from 8 to 67%.
- Trial name
- LongTEAM (NCT04785976)
- Testing
- Surgical clipping and endovascular coiling
- Where
- 2 sites in China
- Volunteers
- 5,000 people
- Sponsor
- Beijing Tiantan Hospital
Subarachnoid Hemorrhage
Prospective Study of Long-term Outcome After Non-aneurysmal Subarachnoid Hemorrhage
Spontaneous subarachnoid hemorrhage (SAH) is usually caused by rupture of an intracranial aneurysm, but in up to 15% of patients with spontaneous SAH, no discernible bleeding source can be identified despite of repetitive…
- Trial name
- NCT02334657
- Testing
- SF-36
- Volunteers
- 173 people
- Sponsor
- University Clinic Frankfurt
Subarachnoid Hemorrhage, Aneurysmal
Risk Factors for Aneurysm Rebleeding
The purpose of this study is to examine the risk factors for aneurysm rebleeding.
- Trial name
- NCT01567449
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Fujian Medical University
Subarachnoid Hemorrhage, Aneurysmal
Trial of Prophylactic Decompressive Craniectomy for Poor-grade Aneurysmal Subarachnoid Hemorrhage
Decompressive craniectomy has been reported for the treatment of patients with aneurysmal subarachnoid hemorrhage (aSAH). But no prospective randomised controlled trials have yet been undertaken to confirm its effect.The purpose…
- Trial name
- NCT02995928
- Testing
- Decompressive craniectomy, Best medical treatment
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Tang-Du Hospital
Intracranial Aneurysm, Intracranial Aneurysm, Wide Neck Aneurysm, Large Neck Aneurysm Lesion
Microvention AnEurysm & STroke Real-life Data cOllection
The MAESTRO registry is a post-market, single-arm, non-interventional, multicenter registry
- Conditions
- Intracranial Aneurysm, Intracranial Aneurysm, Wide Neck Aneurysm, Large Neck Aneurysm Lesion, Aneurysmal Subarachnoid Hemorrhage, Ischemic Stroke
- Trial name
- MAESTRO (NCT06494436)
- Testing
- All Microvention Class III implantable device CE marked, All Microvention Mechanical Thrombectomy Class III device CE marked
- Where
- Spain
- Volunteers
- 1,000 people
- Sponsor
- Microvention-Terumo, Inc.
Aneurysm, Vasospasm
Balloon Prophylaxis of Aneurysmal Vasospasm
The purpose of this study is to determine if early transluminal ballooning of the major cerebral arteries prevents severe vasospasm and improves neurological outcome in patients with Fisher Grade III aneurysmal subarachnoid…
- Trial name
- NCT00282893
- Testing
- transluminal ballooning, currently existing therapies for the treatment of vasospasm
- Where
- 5 sites in United States, Canada and 1 more
- Volunteers
- 170 people
- Sponsor
- University of California, Davis
SAH
Atorvastatin After Aneurysmal Subarachnoid Hemorrhage
The 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, known as statins, have recently been demonstrated to improve endothelial function.
- Trial name
- NCT01569100
- Volunteers
- 278 people
- Sponsor
- Groupe Hospitalier Pitie-Salpetriere
Subarachnoid Hemorrhage, Aneurysmal, Subarachnoid Hemorrhage
Remote Ischemic Preconditioning in Subarachnoid Hemorrhage
Rupture of brain aneurysms is a common cause of death and disability, accounting for as many as 10% of stroke cases in the United States.
- Conditions
- Subarachnoid Hemorrhage, Aneurysmal, Subarachnoid Hemorrhage, Cerebral Vasospasm, Intracranial Aneurysm
- Trial name
- RIPC-SAH (NCT01158508)
- Testing
- Remote ischemic preconditioning
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, Los Angeles
Acute Kidney Injury
Cystatin c: a Biomarker of AKI in Aneurysmal Subarachnoid Haemorrhage Patients
The goal of this observational study is to assess cystatin c as a predictive biomarker of early acute kidney injury in aneurysmal subarachnoid hemorrhage patients.
- Trial name
- NCT06635408
- Testing
- cystatin c
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Aneurysmal Subarachnoid Haemorrhage, World Neurosurgeon Federation Score ≥ III
Cardiac Function in Severe Aneurysmal Subarachnoid Haemorrhage Patients
Cardiac dysfunction can occur in aneurysmal subarachnoid haemorrhage and might impact patient's neurologic outcome Condition Aneurysmal subarachnoid haemorrhage World Neurosurgeon Federation Score ≥ III
- Trial name
- SPLASH (NCT01801800)
- Testing
- Echocardiography
- Where
- 2 sites in France
- Volunteers
- 80 people
- Sponsor
- Nantes University Hospital
Subarachnoid Hemorrhage, Aneurysmal
Predictive Values of Serum Adiponectin Levels in Aneurysmal Subarachnoid Hemorrhage.
The purpose of this study is to evaluate the predictive value of serum adiponectin levels in aneurysmal subarachnoid hemorrhage patients.
- Trial name
- NCT02814162
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
Subarachnoid Hemorrhage, Brain Ischemia
Dapsone Use in Patients With Aneurysmal Subarachnoid Hemorrhage.
Dapsone is a drug that has been used clinically for several decades due to its anti-infective effect, making it widely available. Its neuroprotective effects have been found through its glutamate receptors antagonistic effect.
- Conditions
- Subarachnoid Hemorrhage, Brain Ischemia, Subarachnoid Hemorrhage, Aneurysmal, Aneurysmal Subarachnoid Hemorrhage
- Trial name
- NCT05131295
- Testing
- Dapsone, Aluminum Hydroxide Gel
- Where
- Mexico
- Volunteers
- 49 people
- Sponsor
- El Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez
Subarachnoid Hemorrhage, Aneurysmal, Time Delay
A Multicenter Registry Study of Aneurysmal SAH
Firstly, this study aims at clarifying the current situation of Emergency treatment of aneurysmal subarachnoid hemorrhage (SAH) in China, and analyzing the influencing factors contributing to transport delay, so as to improve the…
- Trial name
- NCT03094975
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Jian-min Liu
Subarachnoid Hemorrhage, Aneurysmal
New Therapeutic System of Ruptured Intracranial Aneurysms Based on Big Data From Chinese Population
This study aims at clarifying the current situation of Emergency treatment of aneurysmal subarachnoid hemorrhage (SAH) in China, and analyzing the safety and efficacy of the treatment strategy between interventional treatment and…
- Trial name
- NATIONAL-2 (NCT03153748)
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Changhai Hospital
Subarachnoid Hemorrhage, Aneurysmal, Emergency Medical Services
A Registry Study for Emergency Medical Service of Aneurysmal Subarachnoid Hemorrhage in China
This is a staged registry study of early treatment strategy management of acute aneurysmal subarachnoid hemorrhage(aSAH) among different economic development levels areas in China.
- Trial name
- CIAP-5 (NCT03115905)
- Where
- 2 sites in China
- Volunteers
- 6,000 people
- Sponsor
- Xuanwu Hospital, Beijing
Subarachnoid Hemorrhage, Aneurysmal
Artificial Intelligence in Subarachnoid Hemorrhage
The overall aim of this study is to, with the help of computer/data scientist and machine learning processes, analyse collected heart rate variability data in order to evaluate whether specific patterns could be found in patients…
- Trial name
- AISAH (NCT04415736)
- Testing
- No intervention, observational study
- Where
- Sweden
- Volunteers
- 64 people
- Sponsor
- Göteborg University
Subarachnoid Hemorrhage, Aneurysmal
Evaluation of Neuroinflamation of SAH
The investigators are planning that can these markers be used a predictive marker at SAH and for this aim we will study both patiens' blood sample and their CT image.
- Trial name
- BAP (NCT03822260)
- Testing
- Bezmialem VAkif Unv. Ethical board
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University