Clinical trials: Antibiotic Associated Diarrhea
Clostridium Enterocolitis, Antibiotic-Associated Diarrhea
Efficacy of Metronidazole Versus Metronidazole and Rifampin in CDAD Treatment
What is the difference between the use of one drug (Oral Metronidazole) versus the use of this same drug combined with another drug (Rifampin) in treatment of bacteria and infection-associated diarrhea in patients? This infection…
- Conditions
- Clostridium Enterocolitis, Antibiotic-Associated Diarrhea, Pseudomembranous Colitis, Pseudomembranous Enterocolitis
- Trial name
- NCT00182429
- Testing
- Metronidazole and Rifampin
- Where
- 4 sites in Canada
- Volunteers
- 100 people
- Sponsor
- McMaster University
Antibiotic-associated Diarrhea
L Rhamnosus ATCC 53103 & L Reuteri DSM 29063 Compared With L Rhamnosus ATCC 53103 for Preventing AAD in Children
This study will use a noninferiority design to examine whether the administration of L rhamnosus ATCC 53103 \& L reuteri DSM 29063 (Flostrum Baby) is no worse than (or as good as) the…
- Trial name
- FLOSTRUM (NCT04277156)
- Testing
- Lactobacillus rhamnosus ATCC 53103 & Lactobacillus reuteri DSM 29063, L rhamnosus ATCC 53103
- Where
- Poland
- Volunteers
- 892 people
- Sponsor
- Medical University of Warsaw
Antibiotic Associated Diarrhoea
Bovine Lactoferrin and Antibiotic-associated Diarrhoea.
This prospective, randomized, parallel-group, double blind, single-center study is to be conducted in the Medical University of Warsaw Public Paediatric Teaching Hospital in following departments: Department of Paediatric…
- Trial name
- BLAAD (NCT02626104)
- Testing
- Bovine lactoferrin, Maltodextrin
- Where
- Poland
- Volunteers
- 156 people
- Sponsor
- Medical University of Warsaw
Clostridioides Difficile Infection
Washed Microbiota Transplantation for Clostridioides Difficile Infection
This is a real-world study to explore the safety and the efficacy of washed microbiota transplantation （WMT） for patients with Clostridioides Difficile Infection （CDI）.
- Trial name
- NCT06106698
- Testing
- WMT
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The Second Hospital of Nanjing Medical University
Antibiotic-associated Diarrhea
Efficacy of a Probiotic Product in Children With Antibiotic-associated Gastrointestinal Disorders
To assess the effect of a probiotic product, when co-administered with antibiotics, on gastrointestinal symptoms following antibiotic treatment in children.
- Trial name
- NCT02722993
- Testing
- Probiotics
- Where
- Poland
- Volunteers
- 117 people
- Sponsor
- Probi AB
Antibiotic Associated Diarrhea, Acute Otitis Media
Effects of Saccharomyces Boulardii CNCM I-745 on Antibiotic-Associated Perturbation in Children Treated for Acute Respiratory Infections (RESTORE Study)
This study aims to evaluate the effect of co-administering the probiotic Saccharomyces boulardii CNCM I-745 with amoxicillin-clavulanic acid on the intestinal and nasopharyngeal microbiota in children diagnosed with acute otitis…
- Conditions
- Antibiotic Associated Diarrhea, Acute Otitis Media, ACUTE SINUSITIS
- Trial name
- RESTORE (NCT07015736)
- Testing
- Amoxicillin-Clavulanic acid 600mg - 42.9 mg/ 5 mL oral suspension, Saccharomyces boulardii CNCM I-745
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Antibiotic Associated Diarrhea, Clostridium Difficile Infection
Probiotic Lactobacillus Reuteri to Prevent Antibiotic-associated Diarrhea and Clostridium Difficile-related Infections in Hospitalized Children
The purpose of this study is to determine if the daily intake of the probiotic Lactobacillus reuteri prevents antibiotic-associated diarrhoea and related Clostridium difficile infections in children and adolescents.
- Conditions
- Antibiotic Associated Diarrhea, Clostridium Difficile Infection, Gastroenteritis
- Trial name
- AADreuter (NCT01295918)
- Testing
- L reuteri in children on antibiotics
- Where
- 2 sites in Bulgaria
- Volunteers
- 100 people
- Sponsor
- St Marina University Hospital, Varna, Bulgaria
Appendicitis, Appendicitis; Perforation
Probiotics and Antibiotic Associated Diarrhea in Pediatric Complicated Appendicitis
To determine the effectiveness of the use of probiotics in patients with a diagnosis of complicated appendicitis on antibiotic associated diarrhea (AAD).
- Trial name
- NCT04529980
- Testing
- Lactobacillus rhamnosus GG (LGG) Probiotic
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- Children's Health
Critical Illness, Antibiotic-associated Diarrhea
Probiotics For The Prevention of Antibiotics Associated Diarrhea in the Pediatric Intensive Care Unit
The goal of this prospective trial is to learn about lactobacillus use in critically ill pediatric patients. The main question[s] it aims to answer are: Is lactobacillus GG effective in preventing antibiotic associated diarrhea…
- Trial name
- NCT06109740
- Testing
- lactobacillus GG
- Volunteers
- 21 people
- Sponsor
- University of South Alabama
Diarrhea Caused by Drug, Abdominal Pain
Combined Lactobacilli (Reuteri LMG P-27481 and GG ATCC 53103) to Prevent Antibiotic Associated Symptoms in Children
This is a prospective multicenter pediatric double-blind, randomized placebo-controlled, parallel group clinical trial intended to evaluate the efficacy, safety and tolerability of a combined probiotic (LGG and L.
- Trial name
- NCT04836013
- Testing
- combined Lactobacilli
- Where
- Italy
- Volunteers
- 216 people
- Sponsor
- Università degli Studi dell'Insubria
Diarrhea, Infantile
Preventing Antibiotic-Associated DiarRhea Using Erceflora
To determine the effectiveness of the pre-biotic Bacillus clausii in preventing antibiotic associated diarrhea among hospitalized immunocompetent Filipino children.
- Trial name
- PADRE (NCT00447161)
- Testing
- Bacillus Clausii Multi ATB Resist
- Where
- Philippines
- Volunteers
- 323 people
- Sponsor
- Sanofi
Antibiotic-associated Diarrhea
Evaluation of the Use of a Probiotic Containing Bifidobacterium Breve PRL2020 in Oral Drops in Preventing Side Effects From Amoxicillin or Amoxicillin/Clavulanic Acid Antibiotic Use
This multicenter, randomized, double-blind, placebo-controlled clinical trial will evaluate the efficacy and safety of the probiotic Bifidobacterium breve PRL2020 (Brevicillin® gocce) in preventing gastrointestinal side effects…
- Trial name
- NCT07234448
- Testing
- Brevicillin® gocce (Bifidobacterium breve PRL2020)
- Where
- Italy
- Volunteers
- 1,100 people
- Sponsor
- Liaquat University of Medical & Health Sciences
Diarrhea, Antibiotic Associated Diarrhea
Lactobacillus Reuteri DSM 17938 in the Prevention of Antibiotic-associated Diarrhea in Children: Protocol of a Randomized Controlled Trial
The aim of this study is to assess the effect of Lactobacillus reuteri DSM 17938 administration for the prevention of diarrhea and AAD in children.
- Trial name
- NCT02871908
- Testing
- Lactobacillus reuteri DSM 17938
- Where
- Poland
- Volunteers
- 250 people
- Sponsor
- Medical University of Warsaw
Antibiotic-associated Diarrhea
The Effect of a Multispecies Probiotic on Reducing the Incidence of Antibiotic-associated Diarrhoea in Children.
In this trial, the investigators aim to assess the effectiveness of a multispecies probiotic consisting of 2 strains of Bifidobacterium (B. bifidum W23, B. lactis W51) and 6 strains of Lactobacillus (L. acidophilus W37, L.
- Trial name
- NCT03334604
- Testing
- Multispecies probiotic
- Where
- 6 sites in Netherlands, Poland
- Volunteers
- 350 people
- Sponsor
- Medical University of Warsaw
Antibiotic-associated Diarrhea
Use of a Dietary Supplement to Support Digestive Health in Children With Chronic Diarrhea
Micronutrients missing in the diet may assist in supporting digestive health in children with chronic GI issues. This study will monitor changes in symptoms associated with digestive problems in children provided with a dietary…
- Trial name
- NCT02856386
- Testing
- polyphenol supplement
- Volunteers
- 50 people
- Sponsor
- LiveLeaf Inc.
Antibiotic Associated Diarrhea, Upper Respiratory Tract Infection
Effectiveness of Saccharomyces Boulardii in Prevention of Antibiotic Associated Diarrhea
Antibiotic-associated diarrhea (AAD) is a common adverse effect in pediatric patients receiving broad-spectrum antibiotics such as co-amoxiclav for upper respiratory tract infections (URTI).
- Trial name
- NCT07785206
- Testing
- Co-amoxiclav, Saccharomyces boulardii
- Where
- Pakistan
- Volunteers
- 88 people
- Sponsor
- University of Child Health Sciences and Children's Hospital, Lahore
Acute Otitis Media
Bio-Kult Infantis® in AAD Prevention in Infants
Background: antibiotic-associated diarrhoea (AAD) is defined as an acute inflammation of the intestinal mucosa associated to the administration of antibiotics.
- Trial name
- NCT03516409
- Testing
- Biokult
- Where
- Italy
- Volunteers
- 276 people, healthy volunteers welcome
- Sponsor
- Probiotics International Ltd.
Antibiotic-associated Diarrhea, Diarrhea
The Impact of Zinc and Probiotics in Preventing Pediatric Antibiotic-Associated Diarrhea in Southern Iran
The Impact of Zinc and Probiotics in Preventing Pediatric Antibiotic-Associated Diarrhea in Southern Iran
- Trial name
- AAD (NCT06665503)
- Testing
- Zinc Supplement, probiotic
- Where
- Iran
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Hormozgan University of Medical Sciences
Antibiotic-associated Diarrhea
Efficacy and Safety of BB-12 Supplemented Strawberry Yogurt For Healthy Children on Antibiotics
Probiotics are live microorganisms that, when administered in adequate amounts, confer a health benefit on the host. One of the most common indications for probiotic treatment is the prevention of antibiotic-associated diarrhea…
- Trial name
- PLAY ON (NCT03181516)
- Testing
- Bifidobacterium animalis subsp. lactis BB-12, Control
- Where
- United States
- Volunteers
- 255 people
- Sponsor
- Georgetown University
Antibiotic-associated Loose/Watery Stools
Efficacy and Safety of a Probiotic Product in Children With Antibiotic-associated Gastrointestinal Disorders.
To assess the tolerability and effect of a probiotic product, when co-administered with antibiotics, on the incidence and duration of loose/watery stools following the antibiotic treatment in children.
- Trial name
- NCT01940913
- Testing
- Probiotic capsules
- Where
- Poland
- Volunteers
- 400 people
- Sponsor
- Probi AB