Clinical trials: Antibiotic Resistance, Microbial
Antibiotic Prescription
Prescription Pattern and Awareness About Antibiotic Prophylaxis and Resistance
To assess the knowledge of Pediatric dentists regarding the prescription of antibiotics, antibiotic prophylaxis and antibiotic resistance
- Trial name
- NCT04031443
- Where
- Egypt
- Volunteers
- 378 people, healthy volunteers welcome
- Sponsor
- Cairo University
Escherichia Coli Infections
Detection of Biofilm Among Uropathogenic Escherichia Coli Clinical Isolates in Suez Canal University Hospitals
This descriptive cross-sectional study will beconducted in Suez Canal University Hospitals (SCUHs) in Ismailia, Egypt. The study aims to detect Escherichia coli biofilm producers to improve prognosis and treatment and reduce…
- Trial name
- NCT06252428
- Where
- Egypt
- Volunteers
- 47 people
- Sponsor
- Suez Canal University
Sepsis, Neonatal Mortality
Clean Trial - Chlorination to Reduce Enteric and Antibiotic Resistant Infections in Neonates
The CLEAN (ChLorine to reduce Enteric and Antibiotic resistant infections in Neonates) cluster randomized controlled trial in western Kenya will evaluate the impact of a multi-component chlorination intervention in health care…
- Conditions
- Sepsis, Neonatal Mortality, Antibiotic Resistant Infection, Enteric Infections
- Trial name
- CLEAN (NCT06824350)
- Testing
- chlorination for water disinfection and surface disinfection, infection prevention and control messaging
- Where
- 2 sites in United States, Kenya
- Volunteers
- 45,450 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Drug Resistant Bacterial Infection
Molecular Diagnostics of Bacterial Infections and Antibiotic Resistance in Blood Samples and Rectal Swabs Using Real Time PCR-ARES PCR Methods
Experimental study without drug and device, on pseudo-anonymized samples archived at the Tropica Biobank. The objective is to evaluate the performance for the identification of microorganisms in blood samples and rectal swabs of…
- Trial name
- NCT06308692
- Testing
- ARES PCR
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Sacro Cuore Don Calabria di Negrar
Malignant Otitis Externa
Microbiological Screening Of Malignant Otitis Externa Patients Presenting at Sohag University Hospitals
This is a prospective study to identify the bacterial and fungal organisms causing Malignant Otitis Externa (MOE) in patients presenting to Sohag University Hospitals.
- Trial name
- MOE Screening (NCT07790679)
- Testing
- ear swab and susceptibility testing
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Sohag University
Sepsis Bacterial, Ebola Virus Disease
Piloting Clinical Bacteriology in the Ebola Virus Disease Care Response
Despite access to experimental Ebola Virus Disease (EVD)-specific treatments, about 30% of patients still die in the Ebola Treatment Centers (ETC) in DRC.
- Conditions
- Sepsis Bacterial, Ebola Virus Disease, Bloodstream Infection
- Trial name
- Bact_EVD (NCT04250168)
- Where
- 2 sites in Democratic Republic of the Congo
- Volunteers
- 43 people
- Sponsor
- Institute of Tropical Medicine, Belgium
Sickle Cell Disease
Nasopharyngeal Bacterial Carriage and Antibiotic Resistance in Children With Sickle Cell Disease in Ile-De-France
The objective of this study is to to determine the rate of nasopharyngeal carriage of Streptococcus pneumoniae (Sp) in children with sickle cell disease over 6 months and under 15 years of age over a 9-month period in…
- Trial name
- DREPANO-BACT (NCT05197205)
- Testing
- nasopharyngeal swabbing
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Bacterial Infections
Hospital Wide Roll-Out of Antimicrobial Stewardship
Dramatic increases in antibiotic utilization in hospitals continue to drive antibiotic resistance among hospital-acquired pathogens. However, 30-50% of the antibiotic use in hospitals is unnecessary or inappropriate.
- Trial name
- NCT01587937
- Testing
- Antibiotic stewardship audit-and-feedback to prescribers of patients receiving 3rd or 10th day of targeted broadspectrum antibiotics
- Where
- Canada
- Volunteers
- 19,220 people
- Sponsor
- Sunnybrook Health Sciences Centre
Detection of Type VI Secretion System in K.Pneumoniae, Detection of Relation to Ab Resistance, Biofilm
Type VI Secretion System in Klebsiella Pneumoniae
Klebsiella pneumoniae (K. pneumoniae) is an important opportunistic pathogen contributing to nosocomial and antimicrobial-resistant infections. The increasing prevalence of infections caused by multidrug-resistant K.
- Trial name
- Klebsiella (NCT05516654)
- Testing
- Routine bacteriological cultures, Identification of the organism and antibiotic sensitivity will be done by VITEK II, Detection of biofilm formation
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Sohag University