Clinical trials: Anxiety, Generalized
Anxiety
Youth Mayo Clinic Anxiety Coach Pilot Study
This research study aims to test the feasibility and effectiveness of using the Mayo Clinic Anxiety Coach smartphone app as an addition to traditional therapy for the treatment of anxiety disorders in youth, particularly those…
- Trial name
- NCT02205177
- Testing
- Mayo Clinic Anxiety Coach
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Stephen Whiteside
Anxiety
Pediatric Anxiety Intervention With an Entertaining Video Game: Feasibility Study
This research study aims to test the feasibility and effectiveness of using an entertaining video game as an addition to traditional therapy for the treatment of anxiety disorders in youth, particularly those youth who may have…
- Trial name
- NCT02713425
- Testing
- Entertaining Video Game
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Anxiety Disorder of Childhood, Separation Anxiety Disorder of Childhood
Brain Response Associated With Parent-based Treatment for Childhood Anxiety Disorders
This study aims to investigate whether a parent-based treatment for childhood anxiety disorders engages child brain circuitry implicated in children's reliance on parents to reduce anxiety (R61), and whether change in child brain…
- Conditions
- Anxiety Disorder of Childhood, Separation Anxiety Disorder of Childhood, Social Anxiety Disorder of Childhood, Generalized Anxiety Disorder
- Trial name
- NCT03585010
- Testing
- Supportive Parenting for Anxious Childhood Emotions, Parent Educational Support, Cognitive-Behavioral Therapy
- Where
- United States
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Yale University
Autism, Asperger's Syndrome
Cognitive-Behavioral Treatment for Anxiety Disorders in Children With Autism Spectrum Disorders
Autism spectrum disorders affect as many as 1 out of 150 children and are related to significant impairment in social, adaptive, and school functioning.
- Conditions
- Autism, Asperger's Syndrome, Generalized Anxiety Disorder, Social Phobia
- Trial name
- NCT01178385
- Testing
- Cognitive-behavioral therapy, Treatment as Usual
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Anxiety Neuroses, Anxiety States, Neurotic
A Study in Pediatric Participants With Generalized Anxiety Disorder
The purpose of this study is to find out if duloxetine [30-120 milligrams (mg)] given once a day by mouth for 10 weeks to children and adolescents, is better than placebo when treating Generalized Anxiety Disorder (GAD).
- Conditions
- Anxiety Neuroses, Anxiety States, Neurotic, Neuroses, Anxiety
- Trial name
- NCT01226511
- Testing
- Duloxetine
- Where
- 24 sites in United States, Mexico and 1 more
- Volunteers
- 281 people
- Sponsor
- Eli Lilly and Company
Cognitive Behavioral Therapy, Autism Spectrum Disorder
Parent-Led Cognitive-Behavioral Teletherapy for Anxiety in Youth With ASD
This study implements an anxiety-focused, parent-led, therapist-assisted cognitive behavioral teletherapy for parents of youth with ASD and anxiety.
- Conditions
- Cognitive Behavioral Therapy, Autism Spectrum Disorder, Anxiety Disorders, Obsessive-Compulsive Disorder
- Trial name
- NCT04111874
- Testing
- Cognitive Behavioral Teletherapy LTA, Cognitive Behavioral Teletherapy STA
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Baylor College of Medicine
Generalized Anxiety Disorder, Social Phobia
Computerized Cognitive Behavioral Therapy for Childhood Anxiety in Community Health Centers
This study will examine the efficacy of a computerized cognitive behavioral therapy (CCBT) program for children with anxiety disorders in community health centers.
- Conditions
- Generalized Anxiety Disorder, Social Phobia, Separation Anxiety Disorder
- Trial name
- NCT01416805
- Testing
- Computerized Cognitive Behavioral Therapy, Treatment as usual
- Where
- 4 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Generalized Anxiety Disorder (GAD), Anxiety, Separation
SPD503 in Subjects Aged 6-17 Years With Generalized Anxiety Disorder (GAD), Separation Anxiety Disorder (SAD), or Social Phobia (SoP)
This study will evaluate the safety and tolerability of SPD503 in subjects aged 6-17 years with GAD, SAD, or SoP based on treatment emergent adverse events (TEAEs), vital signs and ECGs.
- Conditions
- Generalized Anxiety Disorder (GAD), Anxiety, Separation, Phobia, Social
- Trial name
- NCT01470469
- Testing
- SPD503 (extended-release Guanfacine hydrochloride)
- Where
- 33 sites in United States
- Volunteers
- 83 people
- Sponsor
- Shire
Obsessive-Compulsive Disorder in Children, Social Anxiety Disorder of Childhood
Parent-based Treatment for Youth With Anxiety and Obsessive-compulsive Disorder
Anxiety and obsessive-compulsive disorders are the most common mental health disorders in childhood and adolescence. A parenting intervention for youth with anxiety, called Supportive Parenting of Anxious Childhood Emotions…
- Conditions
- Obsessive-Compulsive Disorder in Children, Social Anxiety Disorder of Childhood, Obsessive-Compulsive Disorder in Adolescence, Separation Anxiety
- Trial name
- NCT04922502
- Testing
- Standard SPACE, Bibliotherapy, low therapist contact SPACE
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Anxiety Disorders, Generalized Anxiety Disorder
Computerized Intervention Targeting the Error-Related Negativity and Balance N1 in Anxious Children
Anxiety disorders are the most common form of psychopathology, and frequently begin in childhood, resulting in lifelong impairment.
- Conditions
- Anxiety Disorders, Generalized Anxiety Disorder, Social Anxiety Disorder, Obsessive-Compulsive Disorder
- Trial name
- NCT05503017
- Testing
- Psycho-social, computerized intervention targeting error sensitivity, Psycho-social, computerized intervention on healthy lifestyle choices
- Where
- United States
- Volunteers
- 248 people
- Sponsor
- Florida State University
Major Depressive Disorder, Anxiety Disorder
Ketamine Infusion for Adolescent Depression and Anxiety
The purpose of this study is to determine the tolerability and short-term efficacy of a single ketamine infusion for the treatment of adolescents with 1) medication-refractory major depressive disorder (MDD) and/or 2)…
- Trial name
- NCT02579928
- Testing
- Ketamine, Midazolam
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- Yale University
Autism, Asperger's Syndrome
Cognitive Behavioral Therapy for Anxiety Disorders in Adolescents With Autism
Due to the considerable prevalence of anxiety in youth with autism spectrum disorders, this study seeks to establish the efficacy of a modified cognitive behavioral therapy protocol in 50 adolescents versus other available…
- Conditions
- Autism, Asperger's Syndrome, Pervasive Developmental Disorder Not Otherwise Specified, Generalized Anxiety Disorder
- Trial name
- NCT01563003
- Testing
- Cognitive Behavioral Therapy, Treatment as usual
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Autism, Asperger's Syndrome
Exposure-Focused Family-Based CBT for Youth With ASD and Comorbid Anxiety
Autism spectrum disorders affect as many as 1 out of 88 children and are related to significant impairment in social, adaptive, and school functioning.
- Conditions
- Autism, Asperger's Syndrome, Pervasive Developmental Disorder Not Otherwise Specified, Generalized Anxiety Disorder
- Trial name
- NCT01919970
- Testing
- Cognitive Behavioral Therapy, Treatment as usual
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Anxiety Disorders,Generalized Anxiety Disorder
A Study of Escitalopram in the Treatment of Children and Adolescents With Generalized Anxiety Disorder
This is a study in minors (7 to 17 years old) diagnosed with generalized anxiety disorder (GAD) and evaluated using standard questionnaires as having at least moderate severity of GAD.
- Trial name
- NCT03924323
- Testing
- Escitalopram
- Where
- 39 sites in United States
- Volunteers
- 273 people
- Sponsor
- AbbVie
Autism Spectrum Disorders, Autism
Psychotherapy for Anxiety in Children With Autism Spectrum Disorder
Anxiety disorders affect 40 to 50% of children with autism spectrum disorders (ASD), contributing to substantial distress and impairment.
- Conditions
- Autism Spectrum Disorders, Autism, Asperger's Syndrome, Pervasive Developmental Disability - Not Otherwise Specified
- Trial name
- TAASD (NCT02028247)
- Testing
- Personalized Cognitive-behavioral therapy, Standard Practice Cognitive-behavioral therapy, Treatment as Usual
- Where
- United States
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Cognitive Behavioral Therapy, Autism Spectrum Disorder
Stepped-Care Cognitive-Behavioral Treatment for Youth With ASD and Anxiety
This study implements a parent-led, flexible, individually-tailored cognitive-behavioral intervention for children with ASD and anxiety.
- Conditions
- Cognitive Behavioral Therapy, Autism Spectrum Disorder, Anxiety Disorders, Obsessive-Compulsive Disorder
- Trial name
- NCT03720795
- Testing
- Stepped Care CBT
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Baylor College of Medicine
Anxiety Disorders, Social Phobia
Child and Adolescent Anxiety Disorders (CAMS)
This randomized, controlled trial compared the efficacy of the medication sertraline (Zoloft®), cognitive-behavioral therapy, the combination of these treatments, and placebo for youth with anxiety disorders.
- Conditions
- Anxiety Disorders, Social Phobia, Generalized Anxiety Disorder
- Trial name
- NCT00052078
- Testing
- Sertraline (SRT), Cognitive Behavioral Therapy (CBT)
- Where
- 6 sites in United States
- Volunteers
- 488 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Anxiety, Separation, Psychomotor Agitation
Cartoon Distraction and Parental Presence on Anxiety in Pediatric Anesthesia
Nearly 50% of young children undergoing surgery exhibit high level of anxiety during induction of anesthesia because of exposure to unfamiliar environment and people and separation from parents.
- Trial name
- NCT02027844
- Testing
- Cartoon, parental presence
- Where
- South Korea
- Volunteers
- 117 people
- Sponsor
- Yeungnam University College of Medicine
Anxiety, Pain
An Innovative Tailored Intervention for Improving Children's Postoperative Recovery (WebTIPS)
The goal of this randomized trial is to examine the effectiveness of a tailored Internet-based Preparation Program (WebTIPS) in reducing anxiety and improving the recovery process in children undergoing surgery.
- Conditions
- Anxiety, Pain, Postoperative Behavior
- Trial name
- WebTIPS (NCT03730259)
- Testing
- Web-based Tailored Intervention Preparation for Surgery
- Where
- 2 sites in United States
- Volunteers
- 1,274 people
- Sponsor
- University of California, Irvine
Generalized Anxiety Disorder, Separation Anxiety Disorder
Treatment of Pediatric Anxiety Disorders by Predicting Treatment Response Through Biocellular Markers and Sleep
1 out of 8 children, adolescents, and young adults suffer from an anxiety disorder. Studies over the past decade show that selective serotonin-reuptake inhibitors (SSRIs), a class of medication that treats anxiety in adults, also…
- Conditions
- Generalized Anxiety Disorder, Separation Anxiety Disorder, Social Phobia
- Trial name
- NCT02189213
- Testing
- Sertraline
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute