Clinical trials: Apnea, Obstructive
Morbid Obesity, Obstructive Sleep Apnea Syndrome
LAGB as a Treatment for Morbid Obesity in Adolescents
Laparoscopic adjustable gastric banding (LAGB) has been used worldwide to help selected morbidly obese adults to lose weight. The FDA has approved LAGB only for patients 18 years or older.
- Conditions
- Morbid Obesity, Obstructive Sleep Apnea Syndrome, Metabolic Syndrome, Insulin Resistance
- Trial name
- NCT01045499
- Testing
- Laparoscopic adjustable gastric banding (Allergan Lap Band)
- Where
- United States
- Volunteers
- 137 people
- Sponsor
- Jeffrey L Zitsman, MD
Obstructive Sleep Apnea
Oximetry in Children for Sleep Apnea Diagnosis
Video-polygraphy or video-polysomnography (vP(S)G) is the reference exam for the diagnosis of obstructive sleep apnea syndrome (OSAS) in children as it allows the detection of the respiratory events presented by the child during…
- Trial name
- NCT05634096
- Testing
- Oximetry
- Where
- France
- Volunteers
- 950 people
- Sponsor
- Central Hospital, Nancy, France
Sleep Disordered Breathing, Obstructive Sleep Apnea
Adenotonsillectomy for Obstructive Sleep-Disordered Breathing in Childhood:The Chania Community Oximetry-Based Study
Obstructive sleep-disordered breathing (SDB) in childhood is a disorder of breathing during sleep characterized by intermittent upper airway obstruction.
- Conditions
- Sleep Disordered Breathing, Obstructive Sleep Apnea, Snoring, Obstructive Sleep Disordered Breathing
- Trial name
- NCT01918007
- Testing
- Adenotonsillectomy (AT)
- Where
- 2 sites in Greece
- Volunteers
- 186 people
- Sponsor
- Chania General Hospital "St. George"
Obstructive Sleep Apnea Syndrome in Children
ATT Compared With ATE in OSAS Children
Non-inferiority hypothesis; adenotonsillotomy is equally good as adenotonsillectomy in treating obstructive sleep apnea syndrome (OSAS) in children after one, three and ten years.
- Trial name
- RCT ATE/ATT (NCT01676181)
- Testing
- Adenotonsillectomy, Adenotonsillotomy
- Where
- Sweden
- Volunteers
- 79 people
- Sponsor
- Karolinska University Hospital
Stroke, Transient Ischemic Attack
DOC Utility: Screening of Depression, Obstructive Sleep Apnea and Cognitive Impairment
The primary objective of this study is to determine whether baseline DOC screening can add to clinical and demographic data to predict the occurrence of a composite negative outcome (any of: recurrent stroke, myocardial…
- Conditions
- Stroke, Transient Ischemic Attack, Depression, Obstructive Sleep Apnea
- Trial name
- NCT02363114
- Where
- Canada
- Volunteers
- 6,500 people
- Sponsor
- Dr. Richard H. Swartz
Obstructive Sleep Apnea of Child
SleepPOSAtive Trial
This is a randomized crossover trial of children diagnosed with positional obstructive sleep apnea (POSA) on a baseline polysomnogram (PSG).
- Trial name
- NCT05499455
- Testing
- Positional Sleep Belt, Control
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- The Hospital for Sick Children
Obstructive Sleep Apnea, Respiratory Insufficiency
Study of the Usability and Efficacy of a New Pediatric CPAP Mask
This study will evaluate a newly developed pediatric mask (known as Pixi) on children aged 2-7 using continuous positive airway pressure (CPAP), or Non-invasive ventilation (NIV) treatment.
- Trial name
- NCT01312948
- Testing
- Prototype mask (known as Pixi)
- Where
- Australia
- Volunteers
- 6 people
- Sponsor
- ResMed
Narcolepsy, Obstructive Sleep Apnea
Development and Validation of Pediatric Narcolepsy Patient Reported Outcomes Scale
The purpose of this study is to test a pediatric narcolepsy patient reported outcomes tool to assess pediatric narcolepsy symptoms and their effect on daily functioning and quality of life.
- Trial name
- PN-PROS (NCT05373979)
- Where
- United States
- Volunteers
- 212 people
- Sponsor
- Boston Children's Hospital
Obesity Hypoventilation Syndrome
Alternative of Treatment in Obesity Hypoventilation Syndrome
Primary objectives: evaluate the efficacy of noninvasive ventilation (NIV) treatment versus continuous positive airway pressure (CPAP) and life style modification treatment in Obesity Hypoventilation Syndrome (OHS), with PCO2…
- Trial name
- NCT01405976
- Testing
- life style modification, noninvasive ventilation, CPAP
- Where
- Spain
- Volunteers
- 440 people
- Sponsor
- Sociedad Española de Neumología y Cirugía Torácica
Pediatric Obstructive Sleep Apnea, Down Syndrome (DS)
Pediatric Down Syndrome Post-Approval Study
The purpose of this Post Approval research study is to assess ongoing safety and effectiveness of the Inspire therapy in adolescents and young adults (age 13-18) with Down syndrome and severe sleep apnea.
- Trial name
- NCT06851338
- Testing
- Hypoglossal Nerve Stimulation
- Where
- 6 sites in United States
- Volunteers
- 60 people
- Sponsor
- Inspire Medical Systems, Inc.
Obstructive Sleep Apnea, Difficult Airway
Airway Ultrasound Prediction and Correlation
This is a novel approach to assess the use of ultrasound to support the identification of obstructive sleep apnea syndrome (OSAS) on a screening questionnaire, and potentially to predict a difficult pediatric airway.
- Trial name
- NCT03313947
- Testing
- Ultrasound, Questionnaire
- Where
- United States
- Sponsor
- Vidya Raman
Obstructive Sleep Apnea
Dexmedetomidine Versus Propofol Sedation for Drug-Induced Sleep Endoscopy in Pediatric Obstructive Sleep Apnea
This research study is designed to learn, first, whether two anesthetics have different effects on collapse seen within the upper airway during sleep endoscopy.
- Trial name
- NCT05303987
- Testing
- Propofol sedation, Dexmedetomidine sedation
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Erin Kirkham
Obstructive Sleep Apnea
Clinical Evaluation of an Apnea Index for Diagnosis and Screening of Obstructive Sleep Apnea (OSA)
The study is designed to compare the apnea event recognition capability of the Capnostream 20 with investigational software to polysomnograph recordings scored by a trained analyst.
- Trial name
- NCT01010438
- Where
- 3 sites in Israel
- Volunteers
- 59 people
- Sponsor
- Oridion
Obstructive Sleep Apnea
Comparing Fitbit® Quality of Measured Sleep to Sleep Measured by Polysomnography in the Sleep Lab
This study is to evaluate a commercial tool on the market (Fitbit®) that also quantifies sleep. No one has studied how pediatric patients perform with it and how accurate it is in measuring their quality of sleep.
- Trial name
- NCT03066479
- Testing
- Fitbit, OSA questionnaire, Polysomnography
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Vidya Raman
Obstructive Sleep Apnea Hypopnea Syndrome
Feasibility in Every Day Pratice in an ENT Department and Value of the Automatic Detection of Respiratory Events
The use of respiratory polygraphy (RP) in children for the diagnosis of obstructive sleep apnea hypopnea syndrome (OSAHS) can be challenging: device acceptance, sensors displacement.
- Trial name
- NCT03817762
- Where
- France
- Volunteers
- 54 people
- Sponsor
- University Hospital, Montpellier
Obesity, Obstructive Sleep Apnea Syndrome
Pilot Study to Assess the Effectiveness of Tonsil and Adenoidectomy (T+A) in Overweight Children and Adolescents
Obesity has reached epidemic proportions in the United States with roughly 20% of American children being overweight and has serious consequences such as sleep apnea.Additionally, obesity is known to result in the earlier onset…
- Trial name
- NCT00222963
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Rochester
Obstructive Sleep Apnea
Tonsillectomy in Adults With Tonsillar Hypertrophy and Obstructive Sleep Apnea
The purpose of the study is to determine if tonsillectomy eliminates symptoms of obstructive sleep apnea in patients with obstructive sleep apnea and marked tonsillar hypertrophy with normal soft palate and uvula length.
- Trial name
- NCT02204696
- Testing
- Tonsillectomy
- Where
- United States
- Sponsor
- University of Southern California
Obesity, Childhood, Behavior, Eating
Pediatric Obesity Management Study
Childhood obesity is a critical public health issue. Obesity in childhood is associated with many complications, including high blood pressure, type II diabetes mellitus, abnormal blood lipid values, obstructive sleep apnea…
- Trial name
- NCT05622981
- Testing
- Age-specific educational materials and monitoring
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Corewell Health East
Ehler's Danlos Syndrome, Obstructive Sleep Apnea
Obstructive Sleep Apnoea in Children and Adolescents With Ehlers-Danlos Syndrome
Ehlers-Danlos Syndrome (EDS) is a clinically and genetically heterogeneous group of inherited connective tissue disorders characterized by joint hypermobility, skin hyperextensibility, and tissue fragility.
- Trial name
- NCT02712060
- Testing
- No intervention
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Obstructive Sleep Apnea (Moderate to Severe), Obstructive Sleep Apnea
A Mindfulness-Based Intervention to Improve CPAP
The main purpose of this study is to assess the effectiveness of a mindfulness-based intervention in improving CPAP use compared to online peer support
- Trial name
- NCT05499286
- Testing
- Mindfulness Program
- Where
- Canada
- Volunteers
- 37 people
- Sponsor
- The Hospital for Sick Children