Clinical trials: Appendicitis, Surgery
Complicated Appendicitis, Acute Appendicitis
Antibiotic Instillation in Appendicitis
Appendicitis (inflammation of the wall of the appendix, causing pain and tenderness in the abdomen) has a range of severity that goes from simple to complicated.
- Trial name
- NCT05470517
- Testing
- Ceftriaxone, Intra-peritoneal Fluid Aspiration
- Where
- United States
- Volunteers
- 190 people
- Sponsor
- Johns Hopkins All Children's Hospital
Appendicitis, Surgery
Serum Hyperbilirubinemia as an Early Predictive Factor for Complicated Appendicitis: Single Center Experience
Serum total bilirubin provides a practical guide to early assessment of suspected appendicitis, supporting faster and more proportionate decisions-earlier escalation when overall risk is high and safe observation when it is low.
- Trial name
- NCT07291882
- Testing
- Appendectomy
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- Minia University
ERAS, Surgery
Effect of Modified ERAS Protocol on Clinical Outcomes in Pediatric Patients With Appendectomy
Acute appendicitis is the most common abdominal emergency with more than 15 million cases reported worldwide. Although appendectomy is considered a safe surgical procedure, the incidence of complications is up to 10%.
- Conditions
- ERAS, Surgery, Appendicitis
- Trial name
- NCT05962320
- Testing
- Education and counselling, Avoiding the use of nasogastric catheters, drains and urinary catheters, Stimulation of intestinal motility in the postoperative period
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Karadeniz Technical University
Appendicitis Acute, Peritonitis
Appendicitis in Adults and Children in France-A Prospective Study by the French Surgical Association Multicenter Cohort
Acute appendicitis still represents a surgical challenge, despite profound changes in practice in recent decades. The objective of this study was comprehensively document current surgical practices aimed at improving the…
- Trial name
- APPEA (NCT04214340)
- Testing
- evaluation of practices
- Volunteers
- 2,285 people
- Sponsor
- Association Francaise de Chirurgie
Appendectomy, Appendicitis
Early Detection of Infection Using the Fitbit in Pediatric Surgical Patients
The purpose of this study is to analyze Fitbit data to predict infection after surgery for complicated appendicitis and the effect this prediction has on clinician decision making.
- Conditions
- Appendectomy, Appendicitis, Appendicitis Acute
- Trial name
- i-DETECT (NCT06395636)
- Testing
- Infection-Prediction Algorithm
- Where
- 4 sites in United States
- Volunteers
- 500 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Acute Appendicitis
Laparoscopic Versus Open Appendectomy
Comparison of open and laparoscopic appendectomy
- Trial name
- NCT01967745
- Testing
- laparoscopic appendectomy, open appendectomy
- Where
- Croatia
- Volunteers
- 100 people
- Sponsor
- Varazdin General Hospital
Appendicitis Acute
Surgical Site Infiltration Using Ketamine Versus Bupivacaine for Analgesia in Post-operative Appendectomy Operation
surgical site infiltration using ketamine versus Bupivacaine for analgesia in post-operative Appendectomy operation by Ketamine versus Bupivacaine
- Trial name
- NCT05097118
- Testing
- Ketamine Versus Bupivacaine
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Acute Appendicitis
MANAGEMENT OF APPENDICITIS DURING THE COVID-19 PANDEMIC
During the Covid-19 pandemic, non-operative management for acute appendicitis (AA) was implemented in the UK. The aim of this study was to determine the efficacy and outcomes of conservative versus surgical management of AA…
- Trial name
- observational (NCT04615728)
- Testing
- laparoscopic or open appendicectomy
- Where
- United Kingdom
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Appendicitis
Single Incision Laparoscopic Surgery (SILS) Versus Laparoscopic Appendectomy
This is a prospective trial of single incision versus standard 3-port laparoscopic appendectomy. The hypothesis is that there may a difference in wound infection rates, operative time, doses of analgesics post-operatively, and…
- Trial name
- NCT00981136
- Testing
- Single Incision Laparoscopic Appendectomy, 3 port laparoscopic appendectomy
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- Children's Mercy Hospital Kansas City
Laparoscopic Surgery, Acute Appendicitis With Rupture
Open to Laparoscopic Reverse Conversion of Perforated Appendicitis
A Prospective Randomized Controlled Trial of Reverse Conversion (Open to Laparoscopic) in management of Acute Perforated Appendicitis
- Conditions
- Laparoscopic Surgery, Acute Appendicitis With Rupture, Sepsis, Abdominal Abscess
- Trial name
- reverse (NCT05283733)
- Testing
- reverse conversion technique
- Where
- Egypt
- Volunteers
- 426 people
- Sponsor
- Zagazig University
Perioperative Hyperoxygenation, Wound Infection
Effect of Peri-operative Supplemental Oxygen in Wound Infection After Appendectomy
The study evaluates the role of supplemental hyper-oxygenation given perioperatively on wound site infection after appendectomy.
- Trial name
- NCT02687217
- Testing
- oxygen
- Volunteers
- 60 people
- Sponsor
- Lady Hardinge Medical College
Appendicitis
European Society for Trauma and Emergency Surgery (ESTES) Cohort Study Snapshot Audit 2020 - Acute Appendicitis
Background Acute appendicitis is an extremely common surgical emergency. Traditionally, appendicitis has been managed surgically.
- Trial name
- SnapAppy (NCT04365491)
- Where
- Ireland
- Volunteers
- 4,000 people
- Sponsor
- Gary Alan Bass, MD PhD
Appendicitis, Surgical Site Infection
Transumbilical Laparoscopic Appendectomy
Transumbilical laparoscopic appendectomy (TULA) is increasingly favored in the treatment of appendicitis within the realm of minimally invasive surgical approaches.
- Trial name
- NCT06177418
- Testing
- Transumbilical laparoscopic appendectomy + Glove finger technique, Standard transumbilical laparoscopic appendectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Necmi Kadıoğlu Hospital
Appendicitis Acute, Laparoscopic Surgery
Analysis of Endoloops, Endostaples and Endoclips for Closing the Appendiceal Stump During Laparoscopic Appendectomy
In this randomized control trial the patients with acute appendicitis will be divided in three groups according to the management of the appendiceal stump(Endostapler, Endoloop or Endoclip).
- Trial name
- NCT04083313
- Testing
- Technique used for closing the appendiceal stump
- Where
- Croatia
- Volunteers
- 300 people
- Sponsor
- University Hospital Dubrava
Perforated Appendicitis
Study on Laparoscopic Operation for Perforated Appendicitis
The purpose of this study is to conduct a prospective observational study for the open approach and laparoscopic approach for perforated appendicitis.
- Trial name
- NCT00677989
- Testing
- Laparoscopic appendectomy, Open appendectomy
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Far Eastern Memorial Hospital
Appendicitis
Is Interval Appendectomy Necessary?
Appendicitis is one of the most common surgical problems in children, with 20-35% of patients having perforated by the time they present to a doctor. In these cases, the patient is often treated non-surgically with antibiotics.
- Trial name
- NCT01853683
- Testing
- Conservative Management, Operative Management
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- Children's Hospital of Eastern Ontario
Gastroschisis, Anorectal Malformation
Children's Surgery in Sub-Saharan Africa
Background: Five billion people worldwide do not have access to safe, affordable surgical care. A significant proportion live in sub-Saharan Africa (SSA), where up to 50% of the population are children.
- Conditions
- Gastroschisis, Anorectal Malformation, Appendicitis, Intussusception
- Trial name
- PaedSurgAfrica (NCT03185637)
- Testing
- Various interventions for each of the conditions.
- Where
- United Kingdom
- Volunteers
- 1,407 people
- Sponsor
- King's College London
Acute Appendicitis, Abdominal Pain (AP)
Preserving or Resecting the Normal Appendix in Patients Undergoing Laparoscopy Surgery for Suspected Appendicitis
When appendicitis is suspected, patients are typically planned for emergency surgery preferably using a laparoscopic approach. Up to 20% of these patients will have a normal appendix, thus not suffering from appendicitis.
- Conditions
- Acute Appendicitis, Abdominal Pain (AP), Diagnostic Laparoscopy, Laparoscopic Appendectomy
- Trial name
- NCT06917612
- Testing
- Normal diagnostic laparoscopy, Negative appendectomy
- Volunteers
- 20,000 people
- Sponsor
- Herlev Hospital
Appendiceal Abscess
Early Versus Delayed Operation for Perforated Appendicitis
The objective of this study is to scientifically evaluate two different operative strategies for perforated appendicitis with abscess.
- Trial name
- NCT00414375
- Testing
- Operation on Admission, Drainage and Interval Appendectomy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Children's Mercy Hospital Kansas City
Appendicitis Acute
Evaluation of One Day Discharge After Laparoscopic Appendectomy for Uncomplicated Appendicitis in Children.
The aim of this study was to evaluate the value and safety of discharge of a child to home care within 24 hours after laparoscopic appendectomy for uncomplicated appendicitis to reduce the impact on the child's psyche and need…
- Trial name
- NCT05095987
- Testing
- Laparoscopic Appendectomy
- Where
- Croatia
- Volunteers
- 180 people
- Sponsor
- Miro Jukić