Clinical trials: Arrhythmia, Cardiac
Asthma in Children, Atrial Fibrillation
Mitigating the Health Effects of Desert Dust Storms Using Exposure-Reduction Approaches
The MEDEA project is envisioned to provide the field-based evidence for the adoption of a strategic plan for mitigating the health effects of desert dust storm (DDS) events in South-Eastern Europe.
- Trial name
- MEDEA (NCT03503812)
- Testing
- Intervention (1) for outdoor exposure reduction - Asthma in Children, Intervention (2) for outdoor and indoor exposure reduction - Asthma in Children, Intervention (1) for outdoor exposure reduction - Atrial Fibrillation
- Where
- 3 sites in Cyprus, Greece and 1 more
- Volunteers
- 310 people
- Sponsor
- University of Cyprus
Proton Pump Inhibitor Adverse Reaction, Hypomagnesemia
Hypomagnesemia Associated With Proton-Pump Inhibitor Use
Use of proton pump inhibitors has been associated with hypomagnesemia. However, various case-control or prospective studies have found conflicting results with regards to proton pump inhibitors use and development of…
- Conditions
- Proton Pump Inhibitor Adverse Reaction, Hypomagnesemia, Arrhythmias, Cardiac, Seizures
- Trial name
- PPI_HypoMg (NCT04426994)
- Testing
- proton pump inhibitor use
- Where
- Singapore
- Volunteers
- 211,672 people
- Sponsor
- Changi General Hospital
Arrhythmias, Cardiac
Clinically Indicated Magnetic Resonance Imaging in Patients With Cardiac Devices
Patients with implanted cardiac devices who meet appropriate entrance criteria undergo clinically indicated Magnetic Resonance (MR) Imaging Studies using an established safety protocol.
- Trial name
- NCT01130896
- Where
- United States
- Volunteers
- 1,509 people
- Sponsor
- Johns Hopkins University
Gastroesophageal Reflux, Apnea
Study of Erythromycin in GER-Associated Apnea of the Newborn
To evaluate the relationship of reflux and apnea and to determine whether the administration of erythromycin improves the incidence of GER and GER-associated apnea, bradycardic and/or desaturation events in a prospective…
- Conditions
- Gastroesophageal Reflux, Apnea, Bradycardia
- Trial name
- SEGAN (NCT01825473)
- Testing
- Erythromycin, Multi-channel intra-luminal impedance (MII) pH monitoring
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Calcium Release Deficiency Syndrome (CRDS)
Evaluation of A Clinical Diagnostic Test for CRDS
Calcium Release Deficiency Syndrome (CRDS) is a novel inherited arrhythmia syndrome secondary to RyR2 loss-of-function that confers a risk of sudden cardiac death.
- Trial name
- DIAGNOSE CRDS (NCT06188689)
- Testing
- Pacing
- Where
- 20 sites in United States, Belgium and 5 more
- Volunteers
- 400 people
- Sponsor
- Population Health Research Institute
Arrhythmias, Cardiac
Relevance of Recording an ECG Trace With a Connected Watch
Over the past few years, various systems have been developed to record ECG traces on an ambulatory basis. The latest connected watch models feature 2-electrode ECG recording.
- Trial name
- ECG-MC (NCT06272396)
- Testing
- Smart watch
- Where
- France
- Volunteers
- 3,000 people
- Sponsor
- University Hospital, Bordeaux
Cardiovascular Disease, Atrial Fibrillation
Clinical Decision Support for Stroke Prevention in Atrial Fibrillation
A cluster randomised study in the primary care setting to evaluate a electronic clinical decision tool for stroke prophylaxis in patients with atrial fibrillation.
- Conditions
- Cardiovascular Disease, Atrial Fibrillation, Stroke
- Trial name
- CDS-AF (NCT02635685)
- Testing
- Clinical Decision Support tool
- Where
- Sweden
- Volunteers
- 442,105 people
- Sponsor
- University Hospital, Linkoeping
Atrial Fibrillation
Artificial Intelligence Guided Patient Selection for Atrial Fibrillation Catheter Ablation: Randomized Clinical Trial (AI-PAFA Trial)
Atrial fibrillation (AF) is a major cardiovascular disease with a prevalence of 1.7% of the total population in Korea, associated with 25% of ischemic stroke and 30% of heart failure, and is a major cardiovascular disease that…
- Trial name
- NCT04997824
- Testing
- Artificial Intelligence-based atrial fibrillation catheter ablation, Medical Therapy
- Where
- South Korea
- Volunteers
- 1,000 people
- Sponsor
- Yonsei University
Atrial Fibrillation, Atrial Tachycardia
Modeling of Amiodarone Effect on Heart Rate Control in Critically Ill Patients With Atrial Tachyarrhythmias
Aims Amiodarone is the gold-standard medication to control heart rate in critically ill patients with atrial tachyarrhythmias (ATs); however, effective doses and covariates influencing its efficacy remain unknown.
- Trial name
- AMIRA (NCT03413150)
- Testing
- Amiodarone
- Volunteers
- 80 people
- Sponsor
- Groupe Hospitalier Pitie-Salpetriere
Congenital Heart Defect
Signs and Symptoms Associated With Molecular Defects in Genetically Inherited Heart Disease
Genetically inherited heart diseases (familial cardiopathies) are conditions affecting the heart passed on to family members by abnormalities in genetic information.
- Trial name
- NCT00027196
- Where
- United States
- Volunteers
- 9,999,999 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Death, Sudden, Cardiac, Ventricular Fibrillation
Failure of Chronically Implanted Defibrillator Leads -Incidence and Management
Comparison of two different approaches to address the problem of malfunctioning ICD-leads. These leads consist of two parts. One that is used for detection of arrhythmias(and pacing if required) (Pace/Sense) and a second part…
- Trial name
- NCT00614718
- Where
- 3 sites in Germany, Switzerland
- Volunteers
- 1,317 people
- Sponsor
- University Hospital, Basel, Switzerland
Atrial Fibrillation
Following Patients on Warfarin Therapy to See if Differences in Hemorrhagic Complications Exist
This is a prospective observational cohort study that is in the process of enrolling and following patients on warfarin therapy by utilizing anticoagulation clinics in VA hospitals across the US.
- Trial name
- NCT00075985
- Where
- 17 sites in United States
- Volunteers
- 700 people
- Sponsor
- US Department of Veterans Affairs
Paroxysmal Atrial Fibrillation
Clinical Evaluation of the StablePoint Catheter and Force Sensing System for Paroxysmal Atrial Fibrillation
The NEwTON AF study is a multi-center, global, prospective, single arm study to establish the safety and effectiveness of the IntellaNav StablePoint Catheter and Force-Sensing System in subjects with symptomatic, drug refractory…
- Trial name
- NEwTON AF (NCT04580914)
- Testing
- Treatment with IntellaNav StablePoint Ablation Catheter
- Where
- 47 sites in United States, Austria and 11 more
- Volunteers
- 321 people
- Sponsor
- Boston Scientific Corporation
Arrhythmia, Children
Optimizing Diagnostics Of Arrhythmia Events In Children Using Intelligent Telemetric Solutions
The purpose of this study is to assess efficacy of prolonged Full Disclosure electrocardiogram (ECG) monitoring and signal analysis using advanced telemetric technology to diagnose arrhythmia in comparison with standard…
- Trial name
- TELEMARC2 (NCT01265771)
- Testing
- Prolonged telemetric Full Disclosure ECG recording., Repeated 24 hours ECG Holter monitoring
- Where
- 3 sites in Poland
- Volunteers
- 400 people
- Sponsor
- National Institute of Cardiology, Warsaw, Poland
Dapagliflozin (Forxiga), Atrial Fibrillation (AF)
Dapagliflozin on Outcomes of Rhythm Control Strategy (Pharmacological ± Interventional) in Patient with Atrial Fibrillation
Investigator study the efficacy and safety outcomes of Dapagliflozin use among newly diagnosed Atrial fibrillation patients when underwent rhythm control strategy regardless their diabetic status.
- Trial name
- NCT06759909
- Testing
- Dapagliflozin (DAPA)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cardiomyopathies, Cardiac Arrest
AI-powered ECG Analysis Using Willem™ Software in High-risk Cardiac Patients (WILLEM)
WILLEM is a multi-center, prospective and retrospective cohort study. The study will assess the performance of a cloud-based and AI-powered ECG analysis platform, named Willem™, developed to detect arrhythmias and other abnormal…
- Conditions
- Cardiomyopathies, Cardiac Arrest, Cardiac Arrhythmias, Sudden Cardiac Death
- Trial name
- WILLEM (NCT05890716)
- Testing
- AI-powered ECG analysis to detect cardiac arrhythmic episodes
- Where
- 13 sites in Netherlands, Spain
- Volunteers
- 5,342 people, healthy volunteers welcome
- Sponsor
- Idoven 1903 S.L.
Atrial Fibrillation
Non-vitamin K Oral Anticoagulants in Cardioversion
Non-vitamin K oral anticoagulants (NOAC) have been shown to be safe and effective alternatives to warfarin for stroke prevention in patients with nonvalvular AF (NVAF).
- Trial name
- FinCV3 (NCT02911545)
- Volunteers
- 1,000 people
- Sponsor
- Helsinki University Central Hospital
Stable Angina, Myocardial Infarction
Heart Rate and Cardiovascular Diseases Prognosis in People With Stable Coronary Artery Disease
The Cardiovascular disease research using Linked Bespoke studies and Electronic Records (CALIBER) e-health database was the data resource for this study.
- Conditions
- Stable Angina, Myocardial Infarction, Coronary Heart Disease, Heart Failure
- Trial name
- NCT02244853
- Where
- United Kingdom
- Volunteers
- 51,703 people, healthy volunteers welcome
- Sponsor
- University College, London
Ventricular Fibrillation, Ventricular Tachycardia
Left Ventricular Capture Management Study
Primary Objective: To characterize left ventricular (LV) threshold behavior over time using daily left ventricular capture management (LVCM) measurements.
- Conditions
- Ventricular Fibrillation, Ventricular Tachycardia, Bradyarrhythmia
- Trial name
- LEARN (NCT01089634)
- Where
- Canada
- Volunteers
- 151 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Pericardial Effusion
Impact of Colchicine Therapy on Arrhythmia Recurrence After Acute Pericardial Effusion
The effects colchicine administration for acute pericardial effusion after radiofrequency catheter ablation (RFCA) of atrial fibrillation on the recurrences of arrhythmia.
- Trial name
- NCT02260206
- Testing
- Colchicine
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Yong Seog Oh