Clinical trials: Art
Antiretroviral Toxicity
Surveillance Monitoring for ART Toxicities Study in HIV Uninfected Children Born to HIV Infected Women
SMARTT will estimate the incidence of conditions and diagnoses potentially related to in utero exposure to antiretroviral therapy and/or exposure in the first two months of life among children born of HIV-infected mothers.
- Trial name
- SMARTT (NCT01310023)
- Where
- 22 sites in United States, Puerto Rico
- Volunteers
- 5,169 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Childhood Cancers, Pediatric Oncology
Parent-Child Mandala Painting During Chemotherapy
This randomized controlled trial aims to evaluate the effects of a parent-child mandala painting intervention conducted during the chemotherapy process on caregiver burden, psychological well-being, and child fear and pain levels…
- Trial name
- NCT07363005
- Testing
- Parent-Child Mandala Painting Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Yuzuncu Yil University
Plasmodium Falciparum Malaria
Phase II Dose-ranging Study of Pyronaridine/Artesunate in Adults Patients With Plasmodium Falciparum Malaria
The primary trial objective is to determine the clinically effective dose of orally administered pyronaridine/artesunate (Pyramax®, PA) with a 3:1 ratio to treat adults with acute, symptomatic, uncomplicated P.
- Trial name
- NCT01594931
- Testing
- pyronaridine/artesunate
- Where
- 6 sites in Cambodia, Indonesia and 4 more
- Volunteers
- 477 people
- Sponsor
- Medicines for Malaria Venture
HIV-1 Infection
ADVANCE Study of DTG + TAF + FTC vs DTG + TDF + FTC and EFV + TDF+FTC in First-line Antiretroviral Therapy
This is a non-inferiority (10% non-inferiority margin), study to assess the efficacy and safety of dolutegravir, DTG (50 mg once daily [QD]) administered in combination with tenofovir alafenamide fumarate, TAF (25 mg QD) and…
- Trial name
- ADVANCE (NCT03122262)
- Testing
- Dolutegravir, Tenofovir Alafenamide, Truvada
- Where
- 4 sites in South Africa
- Volunteers
- 1,110 people
- Sponsor
- Professor Francois Venter
Brain Injuries
Expressive Arts as a Social and Community Integration Tool for Youth Recovering From Brain Injury
This study utilizes a novel technique-expressive arts therapy-to facilitate social integration for youth recovering from acquired brain injury (ABI).
- Trial name
- NCT00434603
- Testing
- Expressive Arts--Theatre Skills Training Program
- Volunteers
- 8 people
- Sponsor
- University of Toronto
Human Immunodeficiency Virus
Efficacy Study of Different Laboratory Management Strategies and Drug Regimens in HIV-infected Children in Africa
The two original objectives were to determine in HIV-infected children initiating antiretroviral therapy (ART): 1. Whether clinically driven monitoring (CDM) will have a similar outcome in terms of disease progression or death as…
- Trial name
- ARROW (NCT02028676)
- Testing
- Clinically Driven Monitoring (CDM), Laboratory plus Clinical Monitoring (LCM), Arm A: ABC+3TC+NNRTI
- Where
- 4 sites in Uganda, Zimbabwe
- Volunteers
- 1,206 people
- Sponsor
- Medical Research Council
HIV
Management of Highly Active Anti-retroviral Therapy-related Hyperlipidemia Among HIV-infected Patients in Taiwan
1. Written informed consent must be obtained before any study specific procedures are undertaken. 2. The process of the experiment (brief describe) The patients must come back for follow during 4 to 12 weeks after starting the…
- Trial name
- NCT01697540
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Infertility
Clinical Performance and Safety Investigation of ENDOmetrial Washing MEdical DEvice Forielle
This is a multicenter, prospective randomized controlled, interventional investigation to assess the safety and clinical performance of Forielle, a medical device for endometrial washing, in restoring favorable endometrial…
- Trial name
- ENDOMEDE (NCT03387059)
- Testing
- Forielle
- Where
- 7 sites in Italy
- Volunteers
- 9 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
ART, IVF
Health in Childhood Following Assisted Reproductive Technology
The purpose of this trial is to investigate the metabolic and cardiovascular health in children aged 6-8 years born after in-vitro fertilization with frozen embryo transfer
- Conditions
- ART, IVF, Cardiovascular Risk Factor, Hypertension
- Trial name
- HiCART (NCT03719703)
- Where
- Denmark
- Volunteers
- 606 people, healthy volunteers welcome
- Sponsor
- Anja Bisgaard Pinborg
HIV Infection
Typology of Adherence in Adolescents: Phase II
A number of factors influence HIV-positive adolescents' acceptance of and willingness to continue taking anti-HIV medicines. These factors include mental health and substance abuse issues, barriers such as lack of medical…
- Trial name
- NCT00106678
- Where
- 17 sites in United States, Puerto Rico
- Volunteers
- 1,200 people
- Sponsor
- University of North Carolina, Chapel Hill
Health Related
Newborns From Patients Treated With ART (Assisted Reproductive Technology)
The Prospective Cohort Study for Newborns from patients treated with ART was set up to investigate the short- and long-term health consequences in Reproductive Medical Center, First Affiliated Hospital of Zhengzhou University…
- Trial name
- NCT03993158
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
Acquired Immunodeficiency Syndrome, Infant, Newborn
Safety of Cotrimoxazole in HIV- and HAART-exposed Infants
The purpose of this study is to determine if prophylactic cotrimoxazole makes severe anemia or neutropenia more common in infants exposed to maternal HIV and combination antiretroviral therapy.
- Conditions
- Acquired Immunodeficiency Syndrome, Infant, Newborn, Anemia, Neutropenia
- Trial name
- NCT01086878
- Testing
- cotrimoxazole
- Where
- 2 sites in Botswana
- Volunteers
- 222 people
- Sponsor
- Harvard School of Public Health (HSPH)
Mycobacterium Avium-intracellulare Infection, HIV Infections
A Study to Evaluate the Effects of Azithromycin on MAC Disease Prevention in HIV-Positive Patients
This study is designed to find out whether HIV-positive patients whose immune systems have improved after receiving anti-HIV treatment should take azithromycin to prevent Mycobacterium avium complex (MAC) disease.
- Trial name
- NCT00000947
- Testing
- Azithromycin
- Where
- 19 sites in United States
- Volunteers
- 850 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections
Endothelial Dysfunction as a Risk Factor in HIV Study
Highly active antiretroviral therapy (HAART) has proven effective in altering the natural history of HIV infection in many patients. However, this therapy may not be sustainable because of the toxicities of the medications.
- Trial name
- NCT00039663
- Testing
- Pravastatin, Gemfibrozil, Rosiglitazone
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Sickle Cell Anemia
State Of The Art Functional Imaging In Sickle Cell Disease
Sickle cell anemia (SCA) is a serious blood disease with blood vessel changes leading to brain injury and stroke. Studies show about 11% of patients with SCA will develop obvious stroke before age 20 years, with children less…
- Trial name
- NCT01137721
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- St. Jude Children's Research Hospital
Malaria
A Trial of the Efficacy of Artesunate and Three Quinine Regimens in the Treatment of Severe Malaria in Children at the Ebolowa Regional Hospital - Cameroon
The purpose of the study is to evaluate and compare the efficacy of parenteral artesunate with three quinine regimens in the treatment of severe malaria in children at the Ebolowa Regional Hospital located in the South region of…
- Trial name
- NCT02563704
- Testing
- Artesunate, Quinine
- Volunteers
- 238 people
- Sponsor
- University of Yaounde 1
Uncomplicated P. Falciparum Malaria
SPK Study in Afghanistan
In Afghanistan, studies over the past 15 years have shown a high degree of Plasmodium falciparum resistance to chloroquine. In 2003 the high failure rate of chloroquine against falciparum malaria led the national malaria…
- Trial name
- NCT01707199
- Testing
- Artesunate + Sulphadoxine-pyrimethamine
- Where
- Afghanistan
- Volunteers
- 83 people
- Sponsor
- University of Oxford
Pain, Anxiety
The Effect of Mandala on Nausea, Vomiting, Pain and Anxiety in Chemotherapy Patients
To determine the effect of mandala art therapy (coloring) on nausea, vomiting, pain and anxiety in children receiving outpatient chemotherapy.
- Trial name
- NCT06508632
- Testing
- Mandala group
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Cukurova University
HIV -1 Infection
Early Neutralizing Antibodies in Infants Living With HIV to Enhance Their Life
The goal of this clinical trial is to learn if subcutaneous ePGT121v1-LS added to standard antiretroviral therapy (ART) is safe and helps improve HIV viral suppression in infants living with HIV in South Africa.
- Trial name
- ENABLE 1 (NCT07655128)
- Testing
- Broadly neutralizing antibody (bNAb) ePGT121v1-LS, Saline (0.9% NaCl)
- Volunteers
- 87 people
- Sponsor
- Hospital Universitario 12 de Octubre
HIV
Reducing Mobility-associated Interruption in HIV Treatment in Malawi
The goal of this pilot clinical trial is to assess the feasibility and acceptability of an intervention package designed to reduce mobility-associated interruptions in HIV treatment in people living with HIV in Malawi who are…
- Trial name
- REMIT (NCT07329166)
- Testing
- REMIT intervention package
- Where
- Malawi
- Volunteers
- 400 people
- Sponsor
- University of California, Los Angeles