Clinical trials: Arthritis, Infectious
Organic, Including Symptomatic, Mental Disorders, Substance Use
Exploring the Comorbidity Between Mental Disorders and General Medical Conditions
Mental disorders have been shown to be associated with a number of general medical conditions (also referred to as somatic or physical conditions).
- Conditions
- Organic, Including Symptomatic, Mental Disorders, Substance Use, Schizophrenia, Mood [Affective] Disorders
- Trial name
- COMO-GMC (NCT03847753)
- Testing
- Organic Disorders, Substance Use Disorders, Schizophrenia Disorders
- Volunteers
- 5,940,299 people
- Sponsor
- University of Aarhus
Systemic Lupus Erythematosus
Phase I Study of Immune Ablation and CD34+ Peripheral Blood Stem Cell Support in Patients With Systemic Lupus Erythematosus
OBJECTIVES: I. Determine the safety of immune ablation with high-dose cyclophosphamide and anti-thymocyte globulin followed by peripheral blood stem cell support in patients with systemic lupus erythematosus.
- Trial name
- NCT00017641
- Testing
- anti-thymocyte globulin, cyclophosphamide, filgrastim
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Northwestern Memorial Hospital
Infection, Immune Deficiency
Personalized Immunotherapeutic for Antibiotic-resistant Infection
M. A. suffers from hypogammaglobulinemia that has been complicated by refractory Mycoplasma hominis septic arthritis. He has been receiving the antibiotic valnemulin under Emergency Investigational New Drug (eIND) 114686…
- Conditions
- Infection, Immune Deficiency, Hypogammaglobulinemia, Septic Arthritis
- Trial name
- NCT02508584
- Testing
- anti-mycoplasma hominis antibodies
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Brigham and Women's Hospital
Gonococcal (GC) Infection, Arthritis, Infectious
Epidemiology of Gonococcal Arthritis (EpGAr)
The aim of this retrospective observational study was to describe the epidemiology of Neisseria gonorrhoeae septic arthritis over the last 10 years at Brest and Rennes university hospitals.
- Trial name
- EpGAr (NCT06897943)
- Where
- 2 sites in France
- Volunteers
- 11 people
- Sponsor
- University Hospital, Brest
Chronic Hepatitis B, Rheumatoid Arthritis
Study of Anti-Viral Prophylaxis for HBsAg(+) or HBcAb(+)/HBsAb(-) Patients Starting Anti-TNFα
Analysis of effect of anti-TNFα treatment on HBV reactivation among patients with systemic rheumatic disease, especially rheumatoid arthritis
- Conditions
- Chronic Hepatitis B, Rheumatoid Arthritis, Ankylosing Spondylitis, Psoriatic Arthritis
- Trial name
- NCT01694264
- Testing
- Entecavir
- Where
- 22 sites in South Korea
- Volunteers
- 43 people
- Sponsor
- Seoul National University Hospital
Gut Microbiome, Gastrointestinal Microbiome
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.
- Conditions
- Gut Microbiome, Gastrointestinal Microbiome, Autism, Autism Spectrum Disorder
- Trial name
- NCT04031469
- Testing
- There is no intervention in this study
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- ProgenaBiome
Axial Spondyloarthritis, Ankylosing Spondylitis
axSEND: Exploring Immune and Microbiota Effects of a Partial Enteral Nutrition Diet in Axial Spondyloarthritis
People with axial spondyloarthritis (axSpA) often have intestinal inflammation and intestinal microbiome dysbiosis, with some similarities to Crohn's-like inflammatory bowel disease (IBD) gut inflammation.
- Conditions
- Axial Spondyloarthritis, Ankylosing Spondylitis, Inflammation, Dysbiosis
- Trial name
- axSEND (NCT06460805)
- Testing
- Partial enteral nutrition
- Where
- 2 sites in United Kingdom
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- NHS Greater Glasgow and Clyde
Ankylosing Spondylitis (AS) / Radiographic Axial SpA (r-axSpA), Non-radiographic Axial Spondyloarthritis (Nr-axSpA)
Chinese Spondyloarthritis Inception Cohort (CESPIC)
The Chinese Spondyloarthritis Inception cohort (CESPIC) was started 2000 as a prospective, longitudinal, multicentre, nationwide study in China on patients with early SpA including ankylosing spondylitis (AS, also known as…
- Conditions
- Ankylosing Spondylitis (AS) / Radiographic Axial SpA (r-axSpA), Non-radiographic Axial Spondyloarthritis (Nr-axSpA), Axial Psoriatic Arthritis (axPsA), Acute Anterior Uveitis (AAU)
- Trial name
- CESPIC (NCT05960864)
- Testing
- Celecoxib
- Volunteers
- 1,000 people
- Sponsor
- Southwest Hospital, China
Septic Arthritis, Inflammatory Arthritis
Differentiate Children Septic and Inflammatory Arthritis by Comparative Analysis
The purpose is to found new biomarker that differentiate septic arthritis and Juvenile Idiopathic Arthritis in children. Synovial liquid and blood samples with proteomic, MiRNA searching, multiplex cytokine analysis and cellular…
- Conditions
- Septic Arthritis, Inflammatory Arthritis, Children
- Trial name
- DIANE (NCT03827759)
- Where
- 5 sites in France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Septic Arthritis
Surgical Management of Knee Septic Arthritis
Surgical excisional debridement is the mainstay of management in septic arthritis with necessary decompression, lavage, debridement, and partial synovectomy. However, there has been considerable debate over the optimal modality.
- Trial name
- NCT04786379
- Testing
- Arthroscopic Irrigation and Debridement, Open Arthrotomy with irrigation and debridement
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Autoimmune Disease, Juvenile Idiopathic Arthritis
Immunogenicity of HPV Vaccine in Immunosuppressed Children
Genital HPV is the necessary cause for cervical cancer, as well as a major contributing cause of several other cancers and conditions. There are now effective vaccines against the main oncogenic HPV types, HPV16 and 18.
- Conditions
- Autoimmune Disease, Juvenile Idiopathic Arthritis, Inflammatory Bowel Disease, Evidence of Liver Transplantation
- Trial name
- NCT02263703
- Testing
- Quadrivalent HPV vaccine
- Where
- Australia
- Volunteers
- 55 people
- Sponsor
- The University of New South Wales
Hip Effusion, Septic Arthritis
Accuracy of Pediatric Emergency Medicine Providers in Diagnosing Hip Effusions Using Point of Care Ultrasound
The purpose of this study is to determine if pediatric emergency medicine providers can accurately diagnose a hip effusion using point-of-care ultrasound (POCUS) compared to radiology ultrasound (RADUS).
- Conditions
- Hip Effusion, Septic Arthritis, Transient Synovitis, Hip
- Trial name
- NCT05971745
- Where
- 6 sites in United States, Australia
- Volunteers
- 161 people
- Sponsor
- Connecticut Children's Medical Center
Septic Arthritis
Extended Hip Ultrasound as Anew Protocol for Septic Hip in Children
To establish a new protocol in order to increase ultrasound diagnostic accuracy of pediatrics presented with signs of septic hip .
- Trial name
- NCT06003374
- Testing
- Ultrasound
- Volunteers
- 46 people
- Sponsor
- Assiut University
Juvenile Idiopathic Arthritis, Arthritis, Septic
Rapid Diagnostic Test for Septic Arthritis
Diagnostic Validation Study of a Test Based on the Analysis of the Proteome by Mass Spectrometry for the Diagnosis of Septic Arthritis in Children Under 16 Years of Age
- Conditions
- Juvenile Idiopathic Arthritis, Arthritis, Septic, Arthritis, Unspecified
- Trial name
- TDR-Arthrite (NCT04460144)
- Testing
- Mass spectrometry
- Where
- France
- Volunteers
- 274 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Lyme Borreliosis, Fibromyalgia
Experiences and Care Pathways Shared on Social Media Regarding 5 Conditions Causing Chronic Pain
Chronic pain is a major symptom shared by several medical conditions. This study focuses on five well-defined chronic diseases : Lyme Borreliosis (LB), Post-Acute COVID-19 Syndrome (PACS or "long COVID"), fibromyalgia…
- Conditions
- Lyme Borreliosis, Fibromyalgia, Rheumatoid Arthritis (RA), Post Acute COVID 19 Syndrome
- Trial name
- NCT07871578
- Where
- France
- Volunteers
- 501 people
- Sponsor
- Central Hospital, Nancy, France
Spondylitis
Efficacy and Safety Study of Infliximab (Remicade) to Treat Early Ankylosing Spondylitis
This is a prospective open-label study to evaluated the efficacy and safety of infliximab(Remicade) in treating of patients with early ankylosing spondylitis (AS).
- Trial name
- NCT00936143
- Testing
- infliximab
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Gu Jieruo
Systemic Lupus Erythematosus
Ultraviolet Light Therapy for Systemic Lupus Erythematosus
OBJECTIVES: I. Evaluate the mechanisms of ultraviolet A-1 light therapy in patients with systemic lupus erythematosus and normal controls.
- Trial name
- NCT00004375
- Testing
- ultraviolet A-1 light treatment
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Center for Research Resources (NCRR)
Septic Arthritis
Short Term Results of Pediatric Septic Hip Arthritis Management in Assiut University Hospitals
Detect short term results of pediatric septic hip arthritis and its risk factors
- Trial name
- NCT05780697
- Testing
- Surgery of Drainage of septic hip arthritis
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Spondylarthropathies; Spondylitis, Ankylosing
Safety of Etoricoxib (MK-0663) in Patients With Spondyloarthropathy (SpA)/Ankylosing Spondylitis (AS) in Sweden (EP07013.013.11.082)
The study is intended to provide additional post-marketing safety data regarding the use of etoricoxib for the indication of ankylosing spondylitis.
- Trial name
- NCT01327638
- Testing
- etoricoxib, Other COX-2 inhibitor, nsNSAIDs
- Volunteers
- 21,108 people
- Sponsor
- Organon and Co
Arthritis, Infectious
Pro-calcitonin for Early Detection of Septic Arthritis
Background: Children presenting with non-traumatic joint pain require different treatment depending on the cause of pain. Septic arthritis, which results from a bacterial infection in the joint, often requires a surgical…
- Trial name
- NCT02085733
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Children's Hospitals and Clinics of Minnesota