Clinical trials: Arthritis, Inflammatory
Anklyosing Spondylitis, Telerehabilitation
Effectiveness of Telerehabilitation in Ankylosing Spondylitis
Purpose of the study: Ankylosing spondylitis (AS) is a chronic disease that affects the spine and joints, causing pain, stiffness, fatigue, and reduced quality of life.
- Trial name
- NCT07503327
- Testing
- Synchronous Telerehabilitation Exercise Program, Asynchronous Telerehabilitation Exercise Program, Brochure Program
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Inonu University
Joint Infection, Infection of Hip Joint (Disorder)
Alpha-Defensin and Synovial Proteins to Improve Detection of Pediatric Septic Arthritis
Differentiating between septic arthritis and other causes of joint inflammation in pediatric patients is challenging and of the utmost importance because septic arthritis requires surgical debridement as part of the treatment…
- Conditions
- Joint Infection, Infection of Hip Joint (Disorder), Infection of Shoulder Joint, Septic Arthritis
- Trial name
- NCT03704766
- Testing
- Synovial Alpha-defensin assay, Synovial Neutrophil elastase assay, Synovial lactate assay
- Where
- 3 sites in United States
- Volunteers
- 442 people
- Sponsor
- Hospital for Special Surgery, New York
Juvenile Idiopathic Arthritis
Effect of Pulsed Magnetic Field Versus Low Level Laser Therapy on Functional Performance in Children With Juvenile Idiopathic Arthritis
the purpose of this study is to compare between the effect of pulsed magnetic field versus low level laser therapy on functional performance in children with juvenile idiopathic arthritis
- Trial name
- NCT06226012
- Testing
- pulsed magnetic field, Low level laser
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Shrouk Abd Elmohsen Taha Basiony Elnhrawy
Osteoarthritis
Effectiveness Of Single Doses Of Ibuprofen In Patients With Osteoarthritis Of The Knee
To demonstrate that new drugs work, many complex multidose studies are often required. The intent of this study is to use Ibuprofen as an example of a marketed pain relief drug to validate a simpler single dose model for future…
- Trial name
- NCT00372801
- Testing
- Ibuprofen
- Where
- Australia
- Volunteers
- 36 people
- Sponsor
- GlaxoSmithKline
Rheumatoid Arthritis, Ultrasonography
The Clinical Feasibilityof a Multi-modal Photoacoustic/Ultrasonic Imaging System in Rheumatoid Arthritis
New type of imaging method is in demand clinically for early detection and treatment guiding of RA. Photoacoustic imaging (PAI), a hot spot in medical imaging society, which combines the merits of optical imaging and US and has a…
- Trial name
- NCT04297475
- Testing
- Multi-modal photoacoustic/ultrasonic (PA/US) imaging system
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Juvenile Dermatomyositis, Rheumatic Diseases
Comparison Of The Effects Of Two Different Exercise Training Based On Internal And External Focus In Children and Adolescents With Rheumatic Diseases
The study aims to compare the effects of two different exercise programs, based on distinct focus strategies, on physical fitness and fatigue in children and adolescents with rheumatic diseases.
- Conditions
- Juvenile Dermatomyositis, Rheumatic Diseases, Juvenile Idiopathic Arthritis (JIA), Familial Mediterranean Fever (FMF)
- Trial name
- NCT07138157
- Testing
- External Focus Exercises, Internal Focus Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Istanbul University - Cerrahpasa
Juvenile Idiopathic Arthritis
A Study of the Safety and Efficacy of CNTO 148 (Golimumab) in Children With Juvenile Idiopathic Arthritis (JIA) and Multiple Joint Involvement Who Have Poor Response to Methotrexate (GO KIDS)
The purpose of this study is to evaluate the efficacy and safety of golimumab (CNTO 148) in patients who have active juvenile idiopathic arthritis (JIA) and at least 5 joints with active arthritis that have poor response to…
- Trial name
- NCT01230827
- Testing
- CNTO 148 (Golimumab), Methotrexate
- Where
- 35 sites in United States, Austria and 10 more
- Volunteers
- 173 people
- Sponsor
- Janssen Research & Development, LLC
Rheumatoid Arthritis
Assessment of Wrist Joint and Knee Joint Inflammation in Patients With Rheumatoid Arthritis by Quantitative Three Dimensional Power Doppler Ultrasonography
The purpose of this study is to: 1. To investigate the wrist joint synovial blood flow intensity and model by quantitative three-dimensional (3D) power Doppler ultrasonography (PDUS) in patients with rheumatoid arthritis before…
- Trial name
- 3D sono in RA (NCT00858169)
- Volunteers
- 49 people
- Sponsor
- Taichung Veterans General Hospital
Osteoarthritis, Arthralgia
Leeches for the Treatment of Knee Osteoarthritis
Previous studies have not addressed the question, whether or not a repeated leeching can supply symptomatic relief of osteoarthritic pain for extended periods of time.
- Trial name
- NCT00435773
- Testing
- Single Leeching, Repeated Leeching after 4 weeks
- Where
- Germany
- Volunteers
- 118 people
- Sponsor
- RWTH Aachen University
Osteomyelitis, Septic Arthritis
Oral-only Antibiotics for Bone and Joint Infections in Children
A nationwide, multicenter, randomized, non-inferiority trial of children with bone and joint infections. The primary objective is to determine if oral-only antibiotics (experimental arm) is non-inferior to initial intravenous…
- Conditions
- Osteomyelitis, Septic Arthritis, Bone Infection, Joint Infection
- Trial name
- CHILD@HOME_BJI (NCT04563325)
- Testing
- Oral co-amoxiclav or oral dicloxacillin only, IV ceftriaxon followed by oral co-amoxiclav or oral dicloxacillin
- Where
- Denmark
- Volunteers
- 180 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Rheumatoid Arthritis
Transplantation of Bone Marrow Derived Mesenchymal Stem Cells in Affected Knee Osteoarthritis by Rheumatoid Arthritis
Osteoarthritis of the knee is one of the most common causes of disability among elderly. Arthritis rheumatoid is an autoimmune disease which causes multi articular arthritis, such as knee osteoarthritis.
- Trial name
- NCT01873625
- Testing
- mesenchymal cell transplantation
- Where
- Iran
- Volunteers
- 60 people
- Sponsor
- Royan Institute
Rheumatoid Arthritis
TrEatment Targets in Rheumatoid Arthritis: TETRA-study
There is currently no cure for rheumatoid arthritis (RA), but many treatment options are available. The central aim of RA treatment is lowering disease activity.
- Trial name
- TETRA (NCT06046950)
- Testing
- Treatment target DAS28CRP-LDA, Treatment target SDAI-remission
- Where
- Netherlands
- Volunteers
- 340 people
- Sponsor
- Sint Maartenskliniek
Arthritis, Rheumatoid
Real-world Clinical Efficacy of Abatacept in the T3 Data Registry
The purpose of this study is to assess the effectiveness of Abatacept in real-world clinical practice. The main hypothesis to be examined in this study is, "Abatacept's effectiveness results in a single real-world clinic (n =…
- Trial name
- NCT01555879
- Testing
- Abatacept
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Arthritis Northwest PLLC
Sacroiliitis
Success Rate of Ultrasound Guided Sacroiliac Joint Injection in Sacroiliitis
To re-investigate the success rate of Ultrasound guided sacroiliac joint steroid injection in depositing the drug inside the joint capsule (confirmed by contrast spread in fluoroscopy) and if there is a difference in clinical…
- Trial name
- NCT04314609
- Testing
- Ultrasonography, fluoroscopy
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Karim Alaaeldin Tawfik
Crohn Disease, Ulcerative Colitis
Safety and Efficacy of Fecal Microbiota Transplantation
The gut microbiota is critical to health and functions with a level of complexity comparable to that of an organ system. Dysbiosis, or alterations of this gut microbiota ecology, have been implicated in a number of disease…
- Conditions
- Crohn Disease, Ulcerative Colitis, Celiac Disease, Irritable Bowel Syndrome
- Trial name
- NCT04014413
- Testing
- Fecal Microbiota Transplantation
- Where
- Hong Kong
- Volunteers
- 450 people
- Sponsor
- Chinese University of Hong Kong
Joint Pain
Genicular Nerve Phenol Neurolysis Versus Radiofrequency Ablation for Pain Relief in Grade 4 Knee Osteoarthritis
The goal of this clinical trial is to compare the efficiency and efficacy of genicular nerves blockade by chemical phenol neurolysis versus radiofrequency ablation in managing pain in patients suffering from grade IV KOA in term…
- Trial name
- NCT06864390
- Testing
- genicular nerve neurolysis
- Volunteers
- 114 people
- Sponsor
- Ain Shams University
Arthritis
Multicentre Canadian Study to Measure the Safety and Efficacy of Radiosynoviorthesis
Radiation synovectomy by intra-articular injection of beta-emitting radionuclides is considered a reliable and easy-to-perform therapy without harmful side-effects for the treatment of inflammatory joint disease in many…
- Trial name
- RSO (NCT01615991)
- Testing
- Radiosynoviorthesis
- Where
- 9 sites in Canada
- Volunteers
- 300 people
- Sponsor
- Centre de recherche du Centre hospitalier universitaire de Sherbrooke
Arthritis, Juvenile Idiopathic
An Internet-based Self-management Program for Adolescents With Arthritis
The purpose of this study is to demonstrate the effectiveness of the "Taking Charge: Managing JIA Online" Internet intervention, when compared with an attention (static education only websites) control group in improving pain and…
- Trial name
- NCT01572896
- Testing
- Taking Charge: Managing JIA Online, Standard Medical Care and JIA Resource Center
- Where
- 11 sites in Canada
- Volunteers
- 333 people
- Sponsor
- The Hospital for Sick Children
Juvenile Idiopathic Arthritis
Magnetic Resonance Imaging (MRI) in Asymptomatic Patients With Juvenile Idiopathic Arthritis (JIA)
Juvenile idiopathic arthritis (JIA) may progress asymptomatically leading to joint destruction despite treatment. The aim of the observational study is to describe patients with silent arthritis comparing symptoms, clinical…
- Trial name
- NCT00800371
- Testing
- intra-articular steroid injection
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University Hospital Tuebingen
Autoimmune Pancytopenia, Autoimmune Lymphoproliferative Syndrome (ALPS)
Sirolimus for Autoimmune Disease of Blood Cells
Treatment for patients with autoimmune destruction of blood cells is poor. The part of the body that fights infections is called the immune system and white blood cells (WBCs) are part of the immune system.
- Conditions
- Autoimmune Pancytopenia, Autoimmune Lymphoproliferative Syndrome (ALPS), Evans Syndrome, Idiopathic Thrombocytopenic Purpura
- Trial name
- NCT00392951
- Testing
- sirolimus
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Children's Hospital of Philadelphia
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