Clinical trials: Ascites
Hepatitis B, HIV Infection
Adefovir Dipivoxil to Treat Hepatitis B in HIV-Infected Patients
This study will evaluate the safety and effectiveness of adding the experimental drug adefovir dipivoxil to lamivudine for treating hepatitis B virus (HBV) infection in HIV-infected patients with liver cirrhosis.
- Trial name
- NCT00013702
- Testing
- Adefovir
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Ultrasound in Ascites
Ultrasound and Ascites
The aim of this study is to evaluate the role of ultrasound in the detection, characterization, and determination of the underlying cause of ascites in patients attending Assiut University Hospital
- Trial name
- NCT07196553
- Testing
- Ultrasound
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Assiut University
Ascites
Diagnosis of Ascites in Infants and Children
Ascites is the pathologic accumulation of fluid within the peritoneal cavity. Causes of ascites in infants and children :hepatobiliary disorders,serositis, neoplasm, cardiac, genitourinary disorder, metabolic disease and others.
- Trial name
- Ascites (NCT03341221)
- Volunteers
- 50 people
- Sponsor
- Assiut University
Ascites, Peritoneal Carcinomatosis
Comparison of "Roll-over' Technique With Standard Abdominal Paracentesis in Suspected Peritoneal Carcinomatosis
The study will be a randomized trial that will compare two techniques of abdominal paracentesis in patients with suspected peritoneal carcinomatosis.
- Conditions
- Ascites, Peritoneal Carcinomatosis, Peritoneum Neoplasm, Tuberculous Peritonitis
- Trial name
- ROLLON (NCT04232384)
- Testing
- Standard Paracentesis, Roll Over Paracentesis
- Where
- India
- Volunteers
- 71 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Lymphatic Diseases, Lymphatic Abnormalities
A Prospective Natural History Study of Lymphatic Anomalies
Background: The lymphatic system is a network of vessels that carry a clear fluid called lymph through the body. Problems in the lymphatic system can cause pain, fluid buildup, and issues with immunity.
- Trial name
- NCT05731141
- Where
- 2 sites in United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Cirrhotic Ascitic Patients
Clinical Value of the Developed Scoring Systems for Predicting Spontaneous Bacterial Peritonitis in Cirrhotic Ascites
Liver cirrhosis is the clinical end stage of different entities of chronic liver disease when patients suffer from considerable mortality and morbidity, both of which are correlated positively with disease severity.
- Trial name
- NCT06402071
- Testing
- Ascitic fluid study
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Dalia Nasser Mohamed
Liver Cirrhosis, Refractory Ascites
ALFApump System Post Marketing Surveillance Registry
This is a post market surveillance registry to monitor the safety and performance of the ALFApump system.
- Conditions
- Liver Cirrhosis, Refractory Ascites, Malignant Ascites
- Trial name
- 2011-AAR-004 (NCT01532427)
- Where
- 13 sites in Germany, Spain and 2 more
- Volunteers
- 100 people
- Sponsor
- Sequana Medical N.V.
Cirrhosis With Ascites
Evaluation of Safety & Efficacy of Synbiotic on the Incidence and Recurrence of Spontaneous Bacterial Peritonitis (SBP) in Cirrhotics
Background: Spontaneous bacterial peritonitis (SBP) is a serious complication in patients of cirrhosis with ascites and may occur despite antibiotic prophylaxis.
- Trial name
- NCT00947336
- Testing
- Norfloxacin + Synbiotic
- Where
- India
- Volunteers
- 110 people
- Sponsor
- Govind Ballabh Pant Hospital
Refractory Ascites, Children, Only
Safety and Efficacy of Midodrine Hydrochloride in the Management of Refractory Ascites Due to Cirrhosis in Children
Ascites in liver cirrhosis is explained by increased production of vasoactive substances leading to renal vasoconstriction and salt and water retention.
- Trial name
- NCT04043858
- Testing
- Midodrine 2.5 mg tab
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- National Liver Institute, Egypt
Effusion Pleural, Ascites
Cell Block Immunohistochemistry in Effusion Cytology
Cytology is usually the first step in investigating serous effusions, to either detect or exclude an underlying malignancy. This study will try to answer the need for improved diagnostic yield of cytologic examination by cell…
- Conditions
- Effusion Pleural, Ascites, Pericardial Effusion
- Trial name
- NCT04279327
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Ascites
Role Of Multi-detector Computed Tomography In Differentiation Between Different Types Of Ascites
Role Of Multi-detector Computed Tomography In Differentiation Between Different Types Of Ascites
- Trial name
- NCT04550091
- Testing
- Detection of ascites using CT
- Volunteers
- 88 people
- Sponsor
- Assiut University
Abdominal Neoplasm, Abdominal Injury
Pediatric Intravenous Contrast-Enhanced Ultrasound(CEUS) in China
The goal of this clinical trial is to evaluate the application of intravenous contrast-enhanced ultrasound examination in children with intra-abdominal diseases that require clear diagnoses.
- Conditions
- Abdominal Neoplasm, Abdominal Injury, Ascites
- Trial name
- CEUS (NCT07113808)
- Testing
- contrast-enhanced ultrasound examination, SonoVue®
- Where
- China
- Volunteers
- 108 people
- Sponsor
- The Children's Hospital of Zhejiang University School of Medicine
Spontaneous Bacterial Peritonitis, Primary Peritonitis
Spontaneous Bacterial Peritonitis: Incidence, Risk Factors and Outcome
Spontaneous bacterial peritonitis (SBP) is a severe complication of ascites in cirrhotic patients. Under clinical experience, this condition seems to be more uncommon in Finland.
- Conditions
- Spontaneous Bacterial Peritonitis, Primary Peritonitis, Ascites
- Trial name
- NCT00490217
- Where
- Finland
- Volunteers
- 240 people
- Sponsor
- Tampere University
Refractory Ascites in Children With Cirrhosis
Efficacy and Safety of Midodrine in Refractory or Recurrent Ascites in Children With Cirrhosis.
Refractory ascites is seen in 17% of cirrhotic patients with the 1year mortality rate being high, upto 20-50% [1]. The pathogenesis of cirrhotic ascites includes release of vasodilatory molecules like nitric oxide, damage…
- Trial name
- NCT05084534
- Testing
- Midodrine, Standard medical treatment
- Where
- India
- Sponsor
- Institute of Liver and Biliary Sciences, India
Ascites, Blunt Abdominal Trauma
Telesonography Adaptation and Use to Improve the Standard of Patient Care Within a Dominican Community
The role of teleradiology has far reaching implications for the health of remote and underserved populations. The ability to coordinate radiographic evaluation and diagnosis from a distance has the potential to raise the standard…
- Conditions
- Ascites, Blunt Abdominal Trauma, Cholelithiasis, Cholecystitis
- Trial name
- NCT00591968
- Testing
- SonoSite Titan portable ultrasound coupled with email telediagnosis
- Where
- Dominican Republic
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Edward Via Virginia College of Osteopathic Medicine
Refractory Malignant Ascites
Analysis of Patients Treated With Bevacizumab Intraperitoneal for the Treatment of Refractory Malignant Ascites
The refractory malignant ascites is a complication of advanced stages of many cancer types. It is characterized clinically by abdominal pressure sensation, shortness of breath and pelvic pain.
- Trial name
- BEVASCITE (NCT02891369)
- Testing
- No intervention. Descriptive study
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Ascites, Cirrhosis
Improving Performance of Paracentesis in Medical Residency Training
The investigators hypothesize that there is significant variability in management of patients with ascites despite guidelines provided by the American Association for the Study of Liver Diseases, the professional organization…
- Trial name
- NCT01403987
- Testing
- Residency Program Teaching, Lecture, Pocket Card Reference
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- Boston Medical Center
Liver Cirrhosis
Midodrine Plus Albumin Versus Midodrine Alone to Prevent Cirrhosis Related Complications in Children With Cirrhosis and Ascites
Children with decompensated cirrhosis are more prone to develop various complications. The pathogenesis of cirrhotic complications (ascites, hyponatremia, acute kidney injury) includes release of vasodilatory molecules like…
- Trial name
- NCT06091345
- Testing
- Midodrine, albumin, Standard Medical Treatment
- Where
- India
- Volunteers
- 61 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Spontaneous Bacterial Peritonitis, Liver Cirrhosis
Role of Probiotics in the Prevention of Spontaneous Bacterial Peritonitis in Cirrhotic Patients: A Randomized Placebo Control Trial
Cirrhotic patients are predisposed to bacterial infection. A large proportion of which is spontaneous bacterial peritonitis(SBP), which are mainly caused by enteric bacteria.SBP in a cirrhotic patients is associated with a high…
- Trial name
- NCT00678613
- Testing
- Probiotics and Norfloxacin
- Where
- India
- Volunteers
- 250 people
- Sponsor
- All India Institute of Medical Sciences
Liver Cirrhoses, Malignant Ascites
International Alfapump Cohort Study
This Registry is designed to follow patients who have been implanted with an alfapump system, which is a newly marketed product from Sequana Medical AG, a Swiss Medical Device company.
- Trial name
- TOPMOST (NCT04326946)
- Testing
- Alfapump
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 400 people
- Sponsor
- Sequana Medical N.V.