Clinical trials: Asthma
Asthma
Steroids In Eosinophil Negative Asthma
Because approximately half of all mild-moderately-severe asthma is persistently non-eosinophilic, it is important to determine prospectively if patients who are persistently non-eosinophilic differ in their benefit from inhaled…
- Trial name
- SIENA (NCT02066298)
- Testing
- Mometasone 220mcg BID, Tiotropium Respimat 5mcg QD
- Where
- 25 sites in United States
- Volunteers
- 295 people
- Sponsor
- Milton S. Hershey Medical Center
Asthma in Children
The Effect of 10-Week Exercise Training on Children With Asthma
The goal of this research is to determine whether 10-weeks of exercise training can benefit asthmatic children and young adults with a history of exercise-induced bronchoconstriction (EIB).
- Trial name
- NCT03716219
- Testing
- Exercise Training
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Irvine
Asthma
Metabolomics in the Diagnosis and Treatment of Asthma in Children
The goal of this observational study is to learn about the metabolomic profile of blood and urine in children 12-17 years with asthma.
- Trial name
- NCT07280364
- Testing
- Standart medical treatment
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Asthma
Study for Asthma Education in Primary Schools
Undertake a study of educational intervention in primary schools in Andalusia HYPOTHESIS: There are differences in quality of life associated with asthma (as measured by the questionnaire PAQLQ) and the level of asthma control in…
- Trial name
- NCT01607749
- Testing
- Educational Program, Usual Asthma Information for teachers
- Where
- 2 sites in Spain
- Volunteers
- 4,506 people, healthy volunteers welcome
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Asthma in Children
Telehealth Education for Asthma Connecting Hospital and Home
The goal of this study is to evaluate the feasibility, acceptability, and preliminary efficacy of a technology-enhanced educational intervention for caregivers and children who are hospitalized due to asthma.
- Trial name
- TEACHH (NCT04995692)
- Testing
- Telehealth Education for Asthma Connecting Hospital and Home, Standard Care (SC) Comparison Group
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Rochester
Lung Diseases, Asthma
Better Asthma Outcomes: Lowering Tobacco Smoke Exposure
To improve disease outcomes through reduction in secondhand tobacco smoke exposure of children with asthma
- Trial name
- NCT00217958
- Testing
- SHS reduction intervention based on social cognitive learning theory
- Sponsor
- Palo Alto Medical Foundation
Severe Eosinophilic Asthma
Real World Evidence of Benralizumab in Eosinophilic Severe AsThma in Russia (BEST)
Benralizumab is a humanised, afucosylated, monoclonal antibody against the interleukin (IL)-5 receptor (IL-5R) α subunit that induces direct, rapid, and near-complete depletion of eosinophils in blood, airway tissue, and bone…
- Trial name
- NCT05271526
- Where
- Russia
- Volunteers
- 3 people
- Sponsor
- AstraZeneca
Chronic Sinusitis, Adenoid Disease - Chronic
Management of Pediatric Chronic Rhinosinusitis in Asthmatic Children
The objectives of this study would be to determine the most effective management for pediatric patients with chronic rhinosinusitis and asthma who fail medical management.
- Trial name
- NCT03336671
- Testing
- Endoscopic Sinus surgery, Adenoidectomy
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Bronchial Asthma
The Registration on the Use of Feilike Heji in Minors
Feilike HeJi is produced by Guizhou Jianxing Pharmaceutical Co. LTD. For the treatment of phlegm heat caused by lung cough phlegm yellow, bronchial asthma, bronchitis, see the syndrome of proprietary Chinese medicine (approval…
- Trial name
- NCT04658992
- Where
- 21 sites in China
- Volunteers
- 3,000 people
- Sponsor
- China Academy of Chinese Medical Sciences
Wheezing, Asthma in Children
Impedance Pneumography in Assessment of Asthma Control in Preschool Children
This study evaluates the value of impedance pneumography, used as overnight home recordings during a longitudinal design, in assessing asthma control in preschool children
- Trial name
- IPAAC (NCT03377192)
- Where
- 2 sites in Finland
- Volunteers
- 53 people
- Sponsor
- HUS Skin and Allergy Hospital
Asthma, Chronic Obstructive Pulmonary Disease (COPD)
A Study to Evaluate the Integrated Dose Counter on an Albuterol Hydrofluoroalkane (HFA) Metered Dose Inhaler (MDI)
This study is evaluating the effectiveness of a dose counter for an inhaler device used to deliver medication to people diagnosed with asthma or COPD.
- Conditions
- Asthma, Chronic Obstructive Pulmonary Disease (COPD), Emphysema, Chronic Bronchitis
- Trial name
- NCT01302587
- Testing
- Albuterol
- Where
- 25 sites in United States
- Volunteers
- 306 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Bronchial Asthma
Two Doses of the Intravenous Magnesium Sulfate Versus the Standard Single Dose ,With/ Without the Nebulized Budesonide For the Management of the Severe Asthma Exacerbation in the Emergency Room; A Randomized Controlled Trial.
Many studies have investigated the efficacy and safety of Intravenous magnesium sulfate and inhaled steroids in addition to the standard treatment for patients with severe asthma attacks.
- Trial name
- NCT02455687
- Testing
- Hi-dose iv MgSO4, Nebulized budesonide, Std-dose iv MgSO4
- Where
- Qatar
- Volunteers
- 240 people
- Sponsor
- Hamad Medical Corporation
Atopic Dermatitis, Ichthyosis
Asthma and Atopic Dermatitis Validation of PROMIS Pediatric Instruments
This is designated to validate patient-reported outcomes (PRO) measures in itch-specific pediatric skin conditions, such as atopic dermatitis, and examine the ability of a modified stigma instrument to assess the severity and…
- Conditions
- Atopic Dermatitis, Ichthyosis, Psoriasis
- Trial name
- NCT03051347
- Testing
- Itch Questionnaire and Interview, Stigma Questionnaire and Interview, Cognitive Interview and PROMIS Itch Questionnaire
- Where
- United States
- Volunteers
- 943 people
- Sponsor
- Northwestern University
Rhinitis, Allergic, Seasonal
Efficacy and Safety of Levocetirizine 8 Weeks Prior and After the Onset of the Grass Pollen Season in Subjects With SAR
Efficacy and Safety of Levocetirizine 8 Weeks Prior and After the Onset of the Grass Pollen Season in Subjects With SAR
- Trial name
- NCT00521040
- Testing
- Levocetirizine dihydrochloride
- Volunteers
- 459 people
- Sponsor
- UCB Pharma
Asthma
Informing Policy to Implement Pediatric Family Engagement in Meaningful Use Stage 3
This study will enroll parents/guardians of children who receive treatment at one of the pediatric primary care practice settings in the Pediatric Research in Office Settings (PROS) network or at the Children's Hospital of…
- Trial name
- NCT01966068
- Testing
- MyAsthma Web Portal
- Where
- 2 sites in United States
- Volunteers
- 294 people
- Sponsor
- Children's Hospital of Philadelphia
Asthma
Efficacy of Ciclesonide Inhaled Once Daily Versus Fluticasone Propionate Inhaled Twice Daily in Children With Asthma (4 to 15 y) (BY9010/M1-205)
The aim of the study is to compare the efficacy of ciclesonide versus fluticasone propionate on lung function, symptoms, and use of rescue medication in children with persistent asthma.
- Trial name
- NCT00163410
- Testing
- Ciclesonide
- Where
- 16 sites in India
- Volunteers
- 500 people
- Sponsor
- AstraZeneca
Pneumonia, Bronchiolitis
Diagnosing Pneumonia Under Low-resource Conditions
Pneumonia is the commonest cause of death in children worldwide, killing 1.5 million children under the age of 5 years, every year. This is more than the number of children dying from AIDS, malaria and tuberculosis combined.
- Conditions
- Pneumonia, Bronchiolitis, Asthma
- Trial name
- NCT01997047
- Where
- Canada
- Volunteers
- 502 people
- Sponsor
- University of British Columbia
Overweight, Childhood, Obesity, Childhood
Comparative-effectiveness of a Healthy Lifestyle and Asthma Management Program, In-person vs. ONline
The goal of this study is to evaluate the effectiveness of CHAMPION ("Comparative-effectiveness of a Healthy lifestyle and Asthma Management Program, In-person vs ONline"), a primary care-based intervention to address childhood…
- Conditions
- Overweight, Childhood, Obesity, Childhood, Asthma in Children
- Trial name
- CHAMPION (NCT06432790)
- Testing
- CHAMPION
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Massachusetts General Hospital
Asthma in Children
Role of Technology in Improving Asthma Management In School Staff
The Asthma First Aid Management for School Staff eBook has been developed for the purpose of providing a multimedia self-directed training resource for school staff.
- Trial name
- NCT03530813
- Testing
- Ebook Asthma First Aid in School Training, Face-To-Face Asthma First Aid in Schools Training
- Where
- Australia
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Sydney Children's Hospitals Network
Asthma
Severe Asthma Research Program
The mission of the SARP is to improve the understanding of severe asthma through integrated study of its clinical and biological features and to evaluate their changes over time.
- Trial name
- SARP (NCT01606826)
- Where
- 8 sites in United States
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
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