Clinical trials: Asthma, Exercise-Induced
Asthma, Bronchoconstriction
Dose Response Study of Levalbuterol in the Prevention of Exercise Induced Bronchoconstriction Compared to Racemic Albuterol in Pediatric Subjects
The purpose of this study is to investigate, using an exercise challenge approach, the dose response of levalbuterol HFA MDI in pediatric subjects with asthma
- Trial name
- NCT00685347
- Testing
- Levalbuterol HFA MDI, Racemic Albuterol
- Where
- 6 sites in United States
- Volunteers
- 33 people
- Sponsor
- Sumitomo Pharma America, Inc.
Asthma, Bronchoconstriction
Dose Response Study of Levalbuterol in the Prevention of Exercise Induced Bronchoconstriction Compared to Racemic Albuterol
The purpose of this study is to investigate, using an exercise challenge approach, the dose response of levalbuterol HFA MDI in adolescent and adult subjects with asthma
- Trial name
- NCT00685425
- Testing
- Levalbuterol HFA MDI, Racemic Albuterol
- Where
- 5 sites in United States
- Volunteers
- 62 people
- Sponsor
- Sumitomo Pharma America, Inc.
Bronchospasm, Activity/Exercise Induced Bronchospasm
A Study Measuring Asthma Control In Pediatric And Adolescent Subjects Whose Asthma Is Worsened By Activity Or Exercise
During this study, your child will need to attend up to 5 office visits and maintain regular telephone contact with the clinic. Certain office visits will include physical exams, medical history review, exercise challenge test…
- Trial name
- NCT00118716
- Testing
- Fluticasone propionate/salmeterol, Fluticasone Propionate
- Where
- 50 sites in United States
- Volunteers
- 248 people
- Sponsor
- GlaxoSmithKline
Asthma, Bronchospasm
Single-Dose Cross-Over Study of the Effects of Albuterol-HFA in Exercise Induced Bronchoconstriction
This clinical study will evaluate and establish the protective effects of Amphastar's Albuterol Sulfate HFA Inhalation Aerosol (Albuterol-HFA), in preventing exercise-induced bronchoconstriction (EIB) in adolescent and adult…
- Trial name
- NCT00634829
- Testing
- albuterol (Armstrong Albuterol HFA), Albuterol Sulfate (Provenetil-HFA)
- Where
- 3 sites in United States
- Volunteers
- 24 people
- Sponsor
- Amphastar Pharmaceuticals, Inc.
Asthma
Effect of Different Anti-Asthmatic Treatments on Lung Function and on Exercise-Induced Bronchoconstriction in Children With Asthma
The present study was conducted to determine the effects of four week treatment with budesonide, montelukast, budesonide with montelukast and budesonide with formoterol in children with atopic asthma on lung function: forced…
- Trial name
- NCT00490243
- Testing
- budesonide and montelukast, budesonide and formoterol, montelukast
- Where
- Poland
- Volunteers
- 150 people
- Sponsor
- Medical University of Lodz
Exercise Induced Bronchospasm
A Study to Assess the Efficacy of Budesonide/Albuterol Metered-dose Inhaler (BDA MDI/PT027) on Exercise-induced Bronchoconstriction in Adults and Adolescents With Asthma
This is a multicenter, randomized, double-blind, single-dose, placebo-controlled, 2-period, crossover study to evaluate the efficacy and safety of budesonide/albuterol metered-dose inhaler (BDA MDI/PT027) as compared with a…
- Trial name
- TYREE (NCT04234464)
- Testing
- Budesonide/albuterol sulfate metered-dose inhaler 160/180 μg
- Where
- 6 sites in United States
- Volunteers
- 60 people
- Sponsor
- Bond Avillion 2 Development LP
Exercise Induced Asthma
A Prospective Study Measuring Exhaled Nitric Oxide in Exercise-Induced Asthma
Exercise induced bronchospasm (EIB), also known as exercise induced asthma (EIA) is a transient obstruction to airflow triggered by exertion.
- Trial name
- NCT01097954
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Winthrop University Hospital
Asthma, Exercise-Induced
Montelukast in Exercise-Induced Bronchospasm - 2004 (0476-275)
The purpose of this study is to determine the effect of an approved medication being studied in support of a new approach in the prevention of exercise-induced asthma (a worsening of asthma caused by exercise, also known as…
- Trial name
- NCT00090142
- Testing
- Comparator: Montelukast
- Volunteers
- 62 people
- Sponsor
- Organon and Co
Exercise Induced Bronchospasm, Athletes
Diagnosis of EIB in Young Elite Athletes (13-18 y)
The investigators recently observed airway inflammation and increased damage-associated molecular pattern (DAMP) level in sputum of children (age 11-12y) and adolescents (18-23y) from elite sport programs in Belgium with…
- Conditions
- Exercise Induced Bronchospasm, Athletes, Adolescent
- Trial name
- NCT03587675
- Testing
- EVH test
- Where
- Belgium
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Asthma, Exercise-Induced
Montelukast in Exercise-Induced Bronchospasm - 2003 (0476-270)
The purpose of this study is to determine the effect of an approved medication being studied in support of a new approach in the prevention of exercise-induced asthma (a worsening of asthma caused by exercise, also known as…
- Trial name
- NCT00092131
- Testing
- Comparator: Montelukast
- Volunteers
- 51 people
- Sponsor
- Organon and Co
Childhood Asthma
More Relaxation by Deep Breath on Methacholine
Deep inhalation (DI) dilates normal airway precontracted with methacholine. The fact that this effect is diminished or absent in asthma could be explained by the presence of bronchial inflammation.
- Trial name
- SouProvocBro (NCT03696602)
- Testing
- bronchial provocation test
- Volunteers
- 78 people
- Sponsor
- Central Hospital, Nancy, France
Exercise-induced Bronchospasm
Comparison of Two Bronchodilator Inhalers in Adolescents and Adults With Exercise-Induced Asthma
This study was designed to examine the effectiveness of two bronchodilator inhalers in patients who have exercise-induced asthma.
- Trial name
- NCT00085774
- Testing
- albuterol aerosol by HFA MDI, albuterol aerosol by HFA BOI
- Where
- 3 sites in United States
- Volunteers
- 24 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Asthma
Comparison of Combination Therapy: Montelukast and Inhaled Steroid on Exercise Induced Bronchoconstriction
The purpose of this study is to compare the effects of 2 weeks therapy of montelukast, budesonide, their combination on exercise induced bronchoconstriction (EIB) and airway inflammation in children and young adults, not on…
- Trial name
- NCT00462592
- Testing
- budesonide, montelukast
- Where
- 2 sites in Canada
- Volunteers
- 18 people
- Sponsor
- Hamilton Health Sciences Corporation
Asthma, Exercise Induced
Role of Leukotrienes and Adenosine in Hyperpnea-induced Bronchospasm
This research is being conducted to help us better understand what causes exercise induced asthma. The investigators hypothesize that two types of chemicals, cysteinyl leukotrienes and adenosine, play an important role.
- Trial name
- NCT00710255
- Testing
- Hyperpnea challenge
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Vermont
Exercise Induced Asthma, Exercise Induced Pharyngeal Collapse
Diagnostics and Quality of Life With EIA and EILO
The purpose of this study is to investigate the quality of life of subjects suffering from dyspnoea while exercising and quantify the number of diagnoses of Exercise induced Asthma (EIA) and Exercise induced laryngeal obstruction…
- Trial name
- NCT03550456
- Testing
- ECC, ECC with CLE, Speech therapy
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Exercise-induced Asthma
Exercise Challenge in a Cold Chamber
The purpose of this study is to compare the exercise-challenge in a cold chamber at 2-4°C to the gold standard the metacholine challenge in subjects showing symptoms of exercise-induced bronchoconstriction.
- Trial name
- NCT02026492
- Testing
- Exercise challenge in a cold chamber, Methacholine challenge, Exercise challenge in room temperature
- Where
- Germany
- Volunteers
- 79 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Exercise Induced Bronchoconstriction, Asthma
Exercise Induced Bronchoconstriction and Field Tests
Asthma and exercise induced bronchoconstriction (EIB) represent an important challenge for the athlete, and correct diagnosis is important as it affects health as well as performance with strict regulations concerning asthma…
- Trial name
- EXCIT (NCT04275648)
- Testing
- AsthmaTuner exercise field test
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Karolinska Institutet
Bronchospasm, Activity/Exercise Induced Bronchospasm
A Study Measuring Asthma Control In Pediatric And Adolescent Subjects Whose Asthma Is Worsened By Activity Or Exercise
During this study, your child will need to attend up to 5 office visits and maintain regular telephone contact with the clinic. Certain office visits will include physical exams, medical history review, exercise challenge test…
- Trial name
- NCT00118690
- Testing
- Fluticasone propionate/salmeterol
- Where
- 51 sites in United States
- Volunteers
- 227 people
- Sponsor
- GlaxoSmithKline
Exercise Induced Asthma
Two Investigational Drugs in the Prevention of Airway Constriction Brought on by Exercise in Participants With Asthma (0476-911)
The purpose of this study is to determine the effect of four weeks of treatment with two investigational drugs (oral versus inhaled administration) plus an inhaled medication in the treatment of airway constriction brought on by…
- Trial name
- NCT00127166
- Testing
- Montelukast sodium, Salmeterol xinafoate, Fluticasone propionate
- Volunteers
- 154 people
- Sponsor
- Organon and Co
Exercise Induced Asthma
Study of Airway Inflammation in Relation to Exercise in Elite Athletes
High school elite training programs are today more and more under development in several 'elite sport schools' in Belgium, in order to select and train future elite athletes already at young age.
- Trial name
- NCT01942096
- Where
- Belgium
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven