Clinical trials: Asymptomatic Condition
Covid19, SARS-CoV-2
Asymptomatic SARS-CoV-2 Detection in Children
The primary objective of this study is quantify the transmission risk posted by SARS-CoV-2 in pre/asymptomatic infected children in order to inform the public health response to the COVID-19 pandemic.
- Trial name
- NCT04853316
- Where
- 5 sites in United States, Canada
- Volunteers
- 372 people
- Sponsor
- University of Calgary
Malaria, Falciparum, Hookworm Infections
Iron Absorption and Utilization in Adolescents Infected With Malaria Parasites, Hookworms or Schistosoma
The aim of this study is to investigate the change in iron metabolism in relation to malaria and helminth infections using a stable isotope technique.
- Conditions
- Malaria, Falciparum, Hookworm Infections, Schistosoma Haematobium
- Trial name
- NCT01163877
- Testing
- Fe-57 orally, Fe-58 intravenously
- Where
- Côte d’Ivoire
- Volunteers
- 43 people
- Sponsor
- Swiss Federal Institute of Technology
COVID-19
Contagiousness and Immunogenicity Status of COVID-19 in Asymptomatic Population (COVID-19 CONDITION)
In late December 2019, a new coronavirus strain emerged in China causing coronavirus disease 2019 (COVID-19). Since then, COVID-19 has become a global pandemic outbreak being declared a "public health emergency of international…
- Trial name
- CONDITION (NCT04389658)
- Where
- Spain
- Volunteers
- 1,526 people, healthy volunteers welcome
- Sponsor
- Igenomix
HIV Infections
A Placebo-Controlled, Phase I Clinical Trial to Evaluate the Safety and Immunogenicity of Recombinant Envelope Proteins of HIV-1 gp160 and gp120 in Children >= 1 Month Old With Asymptomatic HIV Infection
To determine the safety and immunogenicity of gp160 (MicroGeneSys), rgp120/HIV-1MN (Genentech), and rgp120/HIV-1SF2 (BIOCINE) and their adjuvants in HIV-infected children 1 month to 18 years of age.
- Trial name
- NCT00000762
- Testing
- rgp120/HIV-1MN, rgp120/HIV-1 SF-2, gp160 Vaccine (MicroGeneSys)
- Where
- 34 sites in United States, Puerto Rico
- Volunteers
- 72 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
SARS-CoV-2, Influenza A
Clinical Validation of the LumiraDx SARS-CoV-2 & Flu A/B Combo Test
This is a prospective multicenter study conducted to evaluate the performance of the LumiraDx SARS-CoV-2 \& Flu A/B tests at point of care sites.
- Conditions
- SARS-CoV-2, Influenza A, Influenza B, Asymptomatic COVID-19
- Trial name
- ITAP1489 (NCT05787444)
- Testing
- LumiraDx SARS-CoV-2 & Flu A/B
- Where
- United States
- Volunteers
- 1,081 people
- Sponsor
- LumiraDx UK Limited
Malaria,Falciparum, Malaria
CHILD (Child Health and Infection With Low Density) Malaria
This trial will assess the long-term health and socioeconomic impact of interventions targeting low-density malaria infection (LMI) among children in Tanzania
- Trial name
- NCT05567016
- Testing
- Active case detection using molecular testing (ACDm), Passive case detection using molecular testing (PCDm), Control (standard of care)
- Where
- Tanzania
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
COVID-19
Serological and PCR Testing for COVID-19
Richmond Research Institute (RRI) is applying existing and new COVID-19 PCR and antibody tests to help develop methodologies which provide fast and accurate results.
- Trial name
- NCT04404062
- Testing
- Membrane-based immunoassay kit, Quantitative antibody Tests, PCR Test
- Where
- United Kingdom
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Richmond Research Institute
Choledochal Cyst
Clinical Features and Prognosis of Asymptomatic Biliary Dilatation
This study is a multicenter, ambidirectional cohort study aiming to consecutively recruit asymptomatic biliary dilation patients incidentally discovered by imaging from 25 medical centers across China.
- Trial name
- NCT07028164
- Where
- China
- Volunteers
- 1,008 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Refractive Error, Dry Eye
Determination of Cell Population in Solution-Induced Corneal Staining (SICS) and Symptomatic Versus Asymptomatic Lens Wearers
The purpose of the study is to investigate the corneal epithelial cell response associated with lens wear that results in solution-induced corneal staining (Phase1) and to determine the cell appearance in symptomatic and…
- Trial name
- ABBOTSFORD (NCT01629706)
- Testing
- Balafilcon A contact lens, Habitual contact lenses, Renu multi-purpose solution
- Volunteers
- 92 people
- Sponsor
- CIBA VISION
Cardiovascular Diseases
The Usefulness of the HyperQ Stress System in Routine Annual Screening Testing
The main objective of this study is to compare the sensitivity and specificity of a new system for analyzing the electrocardiogram (ECG) to the sensitivity and specificity of a conservative treadmill test in asymptomatic…
- Trial name
- NCT00266435
- Where
- Israel
- Volunteers
- 371 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
COVID-19, Asymptomatic COVID-19
A Clinical Evaluation of Proof Diagnostics Test System Including the Proof Diagnostics Reader and COVID-19 Test
To determine the accuracy of Proof Diagnostics COVID-19 Test in the intended, symptomatic and suspected/at-risk asymptomatic population and point-of-care use as compared to a standard molecular comparator, Quidel Lyra SARS-CoV-2…
- Trial name
- NCT05331976
- Testing
- Proof Lab Test System
- Where
- 3 sites in United States
- Volunteers
- 276 people
- Sponsor
- Proof Diagnostics
Cardiovascular Disease
Defining Late Onset Occult Asymptomatic Cardiotoxicity in Childhood Cancer Survivors Exposed to Anthracycline Therapy
The main hypothesis being tested is that magnetic resonance imaging and serologic biomarkers of apoptosis and extracellular matrix remodeling will precede echocardiographic indices of systolic and diastolic function among…
- Trial name
- NCT01671696
- Testing
- Cardiac MRI
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Connecticut Children's Medical Center
Covid19
Face Masks to Reduce SARS-CoV-2 Infections (COVID-19) in Bangladesh
The primary goal of the village-level intervention is to assess whether mask-wearing reduces community-level asymptomatic and symptomatic SARS-CoV-2 infections, assessed via PCR testing.
- Trial name
- NCT05197725
- Testing
- Face mask, Face mask awareness, Face mask promotion through community values or individual information
- Where
- Bangladesh
- Volunteers
- healthy volunteers welcome
- Sponsor
- Yale University
HIV Infections
A Multi-Center, Placebo-Controlled, Double-Blind, Randomized Trial Comparing the Virologic and Immunologic Activities of 400 Mg Nevirapine in Combination With Zidovudine Versus Zidovudine Alone in Asymptomatic HIV-1 Infected Patients With 4-12 Months of Prior Zidovudine Therapy and 200-500 CD4+ Cell
PRIMARY: To compare the virologic activity (quantitative RNA PCR, quantitative PBMC) of the combination of nevirapine and zidovudine (AZT) versus AZT alone after 3 and 6 months of treatment.
- Trial name
- NCT00002323
- Testing
- Nevirapine, Zidovudine
- Where
- 5 sites in United States
- Volunteers
- 60 people
- Sponsor
- Boehringer Ingelheim
Asymptomatic HIV, HIV Infections
ID and Testing Via Friendship Networks
This is a pilot study with a cross-sectional research design to recruit Hispanic/Latina and African American adolescent and young adult women, aged 13-24 years to serve as index recruiters, who will in turn recruit members of her…
- Trial name
- NCT00841360
- Testing
- Index Recruiter, Friendship Network Member
- Where
- 3 sites in United States
- Volunteers
- 535 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Orthopedic Disorder
Developmental Hip Dysplasia by Ultrasonographic Screening of Asymptomatic Infants at Assiut University Hospital
Developmental dysplasia of the hip (DDH), formerly known as congenital dislocation of the hip, comprises a spectrum of abnormalities that include abnormal acetabular shape (dysplasia) and malposition of the femoral head.
- Trial name
- NCT03476915
- Testing
- ultrasound examination of the hip joint
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Assiut University
Surgery, COVID
Surgery During Covid-19: The Role of Asymptomatic Patients, a Survey
a brief questionnaire to get a clearer picture of the situation regarding surgical patients with special emphasis on asymptomatic Covid-19 patients.
- Conditions
- Surgery, COVID, Asymptomatic Patient, Covid-19
- Trial name
- NCT04344197
- Testing
- global survey
- Where
- Italy
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of Rome Tor Vergata
Malaria, Falciparum
Study of Iron Absorption and Utilization in Asymptomatic Malaria
Anemia is still a main public health problem in sub-Saharan Africa. Anemic women have an increased maternal and perinatal mortality and anemic adults have diminished work capacity.
- Trial name
- NCT01108939
- Testing
- Antimalarial treatment, Observation
- Where
- Benin
- Volunteers
- 23 people
- Sponsor
- Swiss Federal Institute of Technology
Malaria
Primaquine's Gametocytocidal Efficacy in Malaria Asymptomatic Carriers
In this study, the investigators are interested to know if lower doses of Primaquine together with dihydroartemisinin-piperaquine can produce a similar effect of clearing both sexual and asexual parasites in asymptomatic carriers…
- Trial name
- PRINOGAM (NCT01838902)
- Testing
- DHA-PPQ, PQ (0.75), PQ (0.4)
- Where
- The Gambia
- Volunteers
- 467 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Covid19, Asymptomatic Shedding Viral
COVID-19 Rapid Testing for Self-Administration Among an Asymptomatic Sample
Point-of-care testing can provide an additional layer of protection to reduce transmission of COVID-19 safely and effectively in the population, and if such tests can be self-administered, barriers to access may be reduced.
- Trial name
- NCT04896710
- Testing
- SD Biosensor
- Where
- Canada
- Volunteers
- 569 people, healthy volunteers welcome
- Sponsor
- University of British Columbia