Clinical trials: Asymptomatic Condition
COVID-19
Shaping Care Home COVID-19 Testing Policy
The goal of this interventional study is to investigate whether continued use of regular asymptomatic testing in staff is a feasible, effective and cost-effective strategy to reduce the impact of COVID-19 in care homes.
- Trial name
- VIVALDI-CT (NCT05639205)
- Testing
- Lateral Flow Device
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- University College, London
Pain
Effect of Electroacupuncture on Pain Threshold
This study is designed to evaluate whether or not electroacupuncture can have an effect on the pain threshold of the subject, as compared to sham treatment.
- Trial name
- NCT00802165
- Testing
- Electroacupuncture
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Logan College of Chiropractic
HIV Infections
A Phase I/II, Open Label Study to Evaluate the Antiviral Potential of Combination Zidovudine and 2' 3'-Dideoxyinosine (Didanosine) in Patients With Asymptomatic HIV Disease
To assess the safety and to evaluate the anti-HIV effect of low-, moderate-, and high-dose schedules of zidovudine (AZT) plus didanosine (ddI) versus ddI alone in asymptomatic HIV-infected patients.
- Trial name
- NCT00000656
- Testing
- Zidovudine, Didanosine
- Where
- 5 sites in United States
- Volunteers
- 116 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Cardiovascular Diseases
The Usefulness of the HyperQ Stress System in Routine Annual Screening Testing
The main objective of this study is to compare the sensitivity and specificity of a new system for analyzing the electrocardiogram (ECG) to the sensitivity and specificity of a conservative treadmill test in asymptomatic…
- Trial name
- NCT00266435
- Where
- Israel
- Volunteers
- 371 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
HIV Infections
Vitamin B Therapy for Hyperlactatemia
The purpose of this study is to see if vitamin B can treat mild hyperlactatemia (a higher than normal level of lactate in the blood) in patients who take nucleoside reverse transcriptase inhibitors (NRTIs).
- Trial name
- NCT00031057
- Testing
- Thiamine hydrochloride, Riboflavin
- Where
- 3 sites in United States
- Volunteers
- 225 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Congenital Cytomegalovirus Infection
Asymptomatic Congenital CMV Treatment
This is a phase II, open-label trial to evaluate valganciclovir as a treatment to prevent development of sensorineural hearing loss (SNHL) in infants with asymptomatic congenital cytomegalovirus (CMV) infection.
- Trial name
- NCT03301415
- Testing
- Valganciclovir
- Where
- 9 sites in United States
- Volunteers
- 7 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
COVID-19
A Follow-up Study of Asymptomatic Infections and Diagnosed Patients With Covid-19 in Shanghai
This study is to clarify the distribution characteristics, host and clinical characteristics, disease outcome and risk factors, changes of multiple organs such as cardiopulmonary function and changes in social and psychological…
- Trial name
- NCT05387304
- Where
- China
- Volunteers
- 250,000 people
- Sponsor
- Ruijin Hospital
Malaria, Asymptomatic Parasitaemia
Community-Based Cohort Study of Hidden Malaria Infections, Diagnostic Gaps, & Mosquito Vector Dynamics in Odisha, India
The goal of this prospective cohort study is to understand the factors responsible for the persistence of malaria transmission in some areas despite intensive control efforts.
- Trial name
- CSCMi3 (NCT07770048)
- Where
- 2 sites in India
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
HIV Infections
Assessment of Asymptomatic Heart Disease in Children With HIV
The purpose of this study is to perform cardiac evaluation in HIV-1 (predominantly clade C)infected children by history, physical examination, echocardiogram and plasma N-terminal pro-B-type natriuretic peptide (N-BNP)measurement…
- Trial name
- NCT00426374
- Testing
- echocardiography and blood test
- Where
- Israel
- Sponsor
- Hadassah Medical Organization
COVID, SARS-CoV 2
COVID-19: Herd Immunity Study in the Czech Republic
The aim of the SARS-CoV-2-CZ-Preval study is to quantify the prevalence of individuals with a history of SARS-CoV-2 coronavirus infection in the Czech population, except for those diagnosed with COVID-19 by methods based on…
- Trial name
- SARSCoV2CZPrev (NCT04401085)
- Testing
- SARS-CoV-2 diagnostic rapid test, Quantitative analysis of SARS-CoV-2 antibodies
- Where
- Czechia
- Volunteers
- 27,000 people, healthy volunteers welcome
- Sponsor
- Institute of Health Information and Statistics of the Czech Republic
Celiac Disease
Impact of the Diagnosis of Celiac Disease
The main purpose of this study is to assess the impact of the diagnosis of celiac disease on general health, healthcare resource utilization, quality of life and lifestyle.
- Trial name
- NCT01145287
- Where
- Finland
- Volunteers
- 760 people
- Sponsor
- Tampere University Hospital
Malaria Asymptomatic Parasitaemia, Malaria Falciparum
Assessing the Feasibility of Combining Dihydroartemisinin Piperaquine and Primaquine for Malaria Mass Drug Administration in High Endemic Communities in the Eastern Region of Ghana
Previous malaria control studies in Ghana have shown that community-wide approaches can substantially reduce malaria infections.
- Conditions
- Malaria Asymptomatic Parasitaemia, Malaria Falciparum, Malaria Infection, Malaria Transmission
- Trial name
- NCT07389057
- Testing
- DHAP, Single low dose PQ
- Where
- Ghana
- Volunteers
- 9,000 people, healthy volunteers welcome
- Sponsor
- Noguchi Memorial Institute for Medical Research
Increased Drug Resistance, Asymptomatic Infection
Molecular Assessment of Drug Resistance Markers in Asymptomatic Malaria Cases and Malaria Antibody Kinetic
Detection of the drug resistance molecular markers for falciparum and vivax in Longitudinal follow-up samples collected in Shwegyin Township, Bago Region that is Artemisinin Resistance Containment Tier I.
- Conditions
- Increased Drug Resistance, Asymptomatic Infection, Malaria
- Trial name
- NCT02708199
- Volunteers
- 1,179 people, healthy volunteers welcome
- Sponsor
- Department of Medical Research, Lower Myanmar
Atherosclerosis
Natural History of Atherosclerosis
20 patients will be recruited. The aim of the study is to determine the natural progression of atherosclerotic disease.
- Trial name
- NCT00918541
- Where
- 3 sites in Switzerland
- Volunteers
- 30 people
- Sponsor
- University of Zurich
Orthopedic Disorder
Developmental Hip Dysplasia by Ultrasonographic Screening of Asymptomatic Infants at Assiut University Hospital
Developmental dysplasia of the hip (DDH), formerly known as congenital dislocation of the hip, comprises a spectrum of abnormalities that include abnormal acetabular shape (dysplasia) and malposition of the femoral head.
- Trial name
- NCT03476915
- Testing
- ultrasound examination of the hip joint
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Assiut University
HIV Infections
A Placebo-Controlled, Phase I Clinical Trial to Evaluate the Safety and Immunogenicity of Recombinant Envelope Proteins of HIV-1 gp160 and gp120 in Children >= 1 Month Old With Asymptomatic HIV Infection
To determine the safety and immunogenicity of gp160 (MicroGeneSys), rgp120/HIV-1MN (Genentech), and rgp120/HIV-1SF2 (BIOCINE) and their adjuvants in HIV-infected children 1 month to 18 years of age.
- Trial name
- NCT00000762
- Testing
- rgp120/HIV-1MN, rgp120/HIV-1 SF-2, gp160 Vaccine (MicroGeneSys)
- Where
- 34 sites in United States, Puerto Rico
- Volunteers
- 72 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Malaria, Asymptomatic Malaria
Low Dose Primaquine for Clearance of Gametocytes
Primaquine (PQ) is currently the only available drug that can clear mature transmission stages of P. falciparum parasites. PQ was previously shown to clear gametocytes that persist after artemisinin-combination therapy.
- Conditions
- Malaria, Asymptomatic Malaria, Plasmodium Falciparum
- Trial name
- LOPRIM (NCT01935882)
- Testing
- Artemether-lumefantrine combination, Artemether-Lumefantrine with a single dose of 0.25mg/kg primaquine, Artemether-Lumefantrine with a single dose of 0.4mg/kg primaquine
- Where
- Burkina Faso
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Asthma
GSK BHR Study (Sont - Second Study)
The purpose of this study was to determine whether asthma control and reduced bronchial responsiveness could be achieved and maintained at a lower dose of inhaled corticosteroids with ADVAIR DISKUS BID or FP BID in adult and…
- Trial name
- NCT01324362
- Testing
- FP 100mcg, FP 250mcg, FP 500mcg
- Where
- 57 sites in United States, Brazil and 2 more
- Volunteers
- 446 people
- Sponsor
- GlaxoSmithKline
Endometrial Hyperplasia
Women With Asymptomatic Endometrial Hyperplasia
The purpose of this study is to evaluate the clinical meaning of an endometrial hyperplasia diagnosed using a vaginal ultrasound during routine gynecological examination.
- Trial name
- FAME-ENDO (NCT02100137)
- Testing
- vaginal ultrasound
- Where
- Austria
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Neurofibromatosis Type 1
Subtle Myocardial Deformation Abnormalities in Asymptomatic Nf-1 Patients
Subtle myocardial deformation abnormalities in asymptomatic nf-1 patients: is cardiac screening needed?
- Trial name
- NCT02505412
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center