Clinical trials: Autism Spectrum Disorders
Autism Spectrum Disorder (ASD), Neurodevelopmental Disorders
Multi-observational Study for the Early Identification of Autism Spectrum Disorder (ASD) and Other Neurodevelopmental Disorders (NDD) in At-risk Populations
Autism spectrum disorder (ASD) is a neurodevelopmental disorder (NDD) that affects about 78 million people worldwide. Its prevalence and degree of impact on individuals and families place it among disorders of global importance.
- Trial name
- BABY@NET (NCT06915805)
- Where
- 5 sites in Italy
- Volunteers
- 296 people, healthy volunteers welcome
- Sponsor
- Istituto Superiore di Sanità
Autism Spectrum Disorder
Evaluation of Some Inflammatory Markers in Autism Spectrum Disorders
Evaluate some Inflammatory markers [IL-6, IL-8, TNF_alpha] in children with autism spectrum disorder
- Trial name
- NCT05803005
- Testing
- inflammatory marker in autism spectrum disorder
- Volunteers
- 100 people
- Sponsor
- Assiut University
Autism Spectrum Disorder
Combined Photo-Biomodulation At Acupuncture Points, Autologous PRP, and Umbilical Cord-Derived Exosome Therapy in Autism Spectrum Disorder
This randomized controlled trial aims to evaluate the efficacy of a combination of photo-biomodulation at acupuncture points, autologous platelet-rich plasma (PRP), and umbilical cord-derived exosome therapy in children with…
- Trial name
- Biomodulation (NCT06600529)
- Testing
- Photo-Biomodulation, Autologous PRP, Exosome Therapy
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Iffat Anwar Medical Complex
Autism Spectrum Disorder
Investigation of the HDAC4 Copy Number Variation and Its Effect on Gene and Protein Expression in Patients With ASD
Specific Aims of this study: 1. To understand the distribution of HDAC4 CNV in the families of the ASD patients with HDAC4 CNV; 2. To perform the analysis of gene expression; 3.
- Trial name
- NCT03670381
- Testing
- Psychiatric diagnosis
- Where
- Taiwan
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
ASD
A Sensory-Profile Framework for Differentiated Swim Instruction in Autistic Children
Autistic children drown at one-hundred sixty times the rate of their neurotypical peers: a public health crisis that the adapted learning field has only addressed by demonstrating that standard swimming instruction sometimes…
- Trial name
- NCT07699692
- Testing
- sensory-based instruction, standard instruction
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Genesis Indep Research
Autism
Interactive Massage Intervention in Toddlers With Autism Spectrum Disorder
This randomized controlled trial aims to evaluate the efficacy of a 3-month maternal interactive massage intervention in toddlers aged 18-24 months with autism spectrum disorder (ASD).
- Trial name
- IMI-ASD (NCT07876245)
- Testing
- Maternal Interactive Massage, Behavioral
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Autism Spectrum Disorder (ASD), Stereotyped Behavior
Efficacy of Physical Activity for the Management of Stereotyped Behavior and Anxiety in Children With Autism Spectrum Disorder
The primary purpose of the study is to investigate whether physical activity can significantly manage stereotyped behavior and anxiety in children diagnosed with Autism Spectrum Disorder (ASD).
- Conditions
- Autism Spectrum Disorder (ASD), Stereotyped Behavior, Anxiety
- Trial name
- NCT06800001
- Testing
- Physical Activity
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Fatima Jinnah Women University
Autism Spectrum Disorder
Role of Folinic Acid in Improving the Adaptive Skills and Language Impairment in Children With Autism Spectrum Disorder
No such study has been conducted in Pakistan so the primary objective of this study was to determine the role of folinic acid in improving the speech and adaptive skills while secondary objective was improvement of stereotype…
- Trial name
- NCT05013164
- Testing
- Folinic Acid
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Nishtar Medical University
Autism Spectrum Disorder
PEACE for ImPACT Study
Investigators will test the impact of the PEACE implementation toolkit and determine the level of implementation support needed to improve early intervention providers use of caregiver coaching with families of young children…
- Trial name
- NCT06374381
- Testing
- PEACE Online Resources, PEACE Weekly Group Facilitation, PEACE Weekly Individual Facilitation
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Autistic Disorder, Attention Deficit Disorder With Hyperactivity
Atomoxetine Versus Placebo for Symptoms of Attention-Deficit/Hyperactivity Disorder (ADHD) in Children and Adolescents With Autism Spectrum Disorder
The purpose of this study is to determine whether atomoxetine is effective in reducing ADHD (Attention Deficit/Hyperactivity Disorder) symptoms in children and adolescents with ASD (Autism Spectrum Disorder).
- Trial name
- NCT00380692
- Testing
- Atomoxetine
- Where
- 8 sites in Netherlands
- Volunteers
- 97 people
- Sponsor
- Eli Lilly and Company
Autism Spectrum Disorder
Social Groups for Australian Children on the Autism Spectrum
This study evaluates the KONTAKT social skills group training in Australian children on the autism spectrum compared to an active control group which is a group Art class
- Trial name
- NCT04024111
- Testing
- KONTAKT(c), Art group
- Where
- Australia
- Volunteers
- 84 people
- Sponsor
- Curtin University
Phelan-McDermid Syndrome, Autism Spectrum Disorder
Mapping the Genotype, Phenotype, and Natural History of Phelan-McDermid Syndrome
The purpose of this study is to comprehensively characterize PMS using standardized medical, cognitive, and behavioral measures and to track the natural history of the syndrome using repeated longitudinal assessments.
- Conditions
- Phelan-McDermid Syndrome, Autism Spectrum Disorder, Intellectual Disability
- Trial name
- NCT02461420
- Where
- 5 sites in United States
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Pervasive Developmental Disorder
Trial of Low-Dose Naltrexone for Children With Pervasive Developmental Disorder (PDD)
This study will examine the effects of low-dose naltrexone (LDN) on children with autistic spectrum disorders. The investigators hope to show a positive effect on social functioning and language.
- Trial name
- NCT00318162
- Testing
- low dose naltrexone
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Hadassah Medical Organization
Autism Spectrum Disorder
Cerebellar tDCS in Children With Autism Spectrum Disorder
The purpose of this research study is to investigate whether tDCS to the cerebellum (specifically, the right crus I/II area of the cerebellum) of children and young adults with autism spectrum disorders (ASD) is safe and to…
- Trial name
- NCT04446442
- Testing
- tDCS
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Autism
Family-Centered Implementation of Parent Training for Autistic Toddlers in Early Intervention
Early Intervention (EI) systems are ill-equipped to serve the many children 12 to 36 months with early signs or a diagnosis of autism spectrum disorder (ASD).
- Trial name
- NCT07471594
- Testing
- Parent Training
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Autism Spectrum Disorder, Autism
Project AFECT (Autism Family Empowerment Coaching and Training Program)
The goal of this clinical trial is to learn about the journey of families after their child's diagnosis of autism and to help parents understand autism and get the right treatments for their child.
- Conditions
- Autism Spectrum Disorder, Autism, Autism Spectrum Disorders, Autistic Disorder
- Trial name
- AFECT (NCT05910502)
- Testing
- Autism Family Empowerment Coaching and Training Program
- Where
- 2 sites in United States
- Volunteers
- 143 people
- Sponsor
- Stanford University
Autism, Autism Spectrum Disorder
Memantine for the Treatment of Social Deficits in Youth With Disorders of Impaired Social Interactions
This study is a 12-week randomized-controlled trial of memantine hydrochloride (Namenda) for the treatment of social impairment in youth with Non-Verbal Learning Disorder, High-Functioning Autism Spectrum Disorder, and related…
- Conditions
- Autism, Autism Spectrum Disorder, Nonverbal Learning Disability
- Trial name
- NCT03553875
- Testing
- Memantine Hydrochloride
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Massachusetts General Hospital
Autism Spectrum Disorder
Community-based Adaptive Autism Intervention for Toddlers
The proposed study (CAIT: Community-based Adaptive Autism Intervention for Toddlers) aims to determine the most optimal sequence of interventions for improving the social- communicative, language and cognitive outcomes of…
- Trial name
- CAIT (NCT04283045)
- Testing
- JASPER, JASPER Plus+
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- University of California, Los Angeles
Anxiety, Autism
Testing a CBT Program for Anxiety in Teenagers With Autism: A Feasibility Study
The objective is to investigate the feasibility of a newly developed manualised group Cognitive Behavioural Therapy (CBT) programme for anxiety in 15 teenagers (aged 13-17 years) with Autism Spectrum Disorder (ASD).
- Trial name
- NCT04838912
- Testing
- Cool Kids (Chilled) Anxiety program adapted to children and youths with autism and anxiety disorders.
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- University of Aarhus
Anxiety, Autism Spectrum Disorder
The Effect of Aroma on Anxiety Among Children With Autism.
This study evaluates the effects of essential oils on anxiety scores among children who have an autism spectrum disorder. One third of the children will receive a control blend of oils, one third of the children will receive a…
- Trial name
- NCT03489811
- Testing
- Test Essential Oil Blend, Active Essential Oil Blend, Control Blend
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nutraceuticals Research Institute
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