Clinical trials: Autism Spectrum Disorders
Autism Spectrum Disorder
Ketogenic Diet Therapy for Autism Spectrum Disorder
This study will assess the effectiveness of the ketogenic diet (high-fat, low-carbohydrate, and moderate protein) in treating autism spectrum disorder (ASD).
- Trial name
- NCT02477904
- Testing
- Ketogenic Diet
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Shriners Hospitals for Children
Cognition
Effects of Hyperbaric Oxygen Therapy on Cognitive Function on Autistic Spectrum Disordered Children
HYPOTHESIS 1. Hyperbaric Oxygenation Therapy will be safe to use with neurotypical adults and children. 2. Hyperbaric Oxygenation Therapy will have a statistically significant positive effect on measures of cognitive function in…
- Trial name
- NCT00631215
- Testing
- Hyperbaric oxygen therapy
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Pediatric Partners of Ponte Vedra
Autism Spectrum Disorder, Parenting
Evaluating a Web Delivered Behavioral Parent Training Intervention for Rural Parents of Children With Autism Spectrum Disorder
For parents of children with autism spectrum disorder (ASD), the severity of the child's behavior negatively correlates with parental well-being.
- Conditions
- Autism Spectrum Disorder, Parenting, Parenting Intervention
- Trial name
- NCT05554198
- Testing
- Attend Behavior Parent Training
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Ohio State University
Autism
the Efficacy of Oral Motor Therapy in Children With Autism
Children with Autism spectrum disorders have speech disorders, which in turn aggravate communication difficulties and lead to an increase in their core symptoms.
- Trial name
- NCT05406076
- Testing
- oral motor therapy, ABA
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Autism, Autism Disorders and Maternal Stress
Adapting the Sensory Environment to Reduce Stress in Children With Autism During Dental Visits
This study aims to evaluate the impact of a sensory-adapted dental environment (SADE) on the stress levels and behavioral responses of children with autism spectrum disorder (ASD) during dental visits.
- Conditions
- Autism, Autism Disorders and Maternal Stress, Sensory Integration Disorder, Stress Biomarkers
- Trial name
- SMILED (NCT07887243)
- Testing
- Sensory-Adapted Dental Environment
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Jagiellonian University
Autism Spectrum Disorder (ASD)
AB-2004 in Treatment of Irritability Associated With Autism Spectrum Disorder (ASD)
The purpose of this study is to establish the potential benefits, safety, and tolerability of AB-2004 in participants with irritability associated with autism spectrum disorder.
- Trial name
- NCT04895215
- Testing
- AB-2004
- Where
- 24 sites in United States, Australia and 1 more
- Volunteers
- 156 people
- Sponsor
- Vertero Therapeutics
Autism Spectrum Disorder
Study to Assess the Janssen Autism Knowledge Engine in Participants With Autism Spectrum Disorder and in a Normally Developing Cohort
The purpose of this study is to evaluate the utility of and to clinically validate the Autism Behavior Inventory (ABI) in measuring clinical symptoms of Autism Spectrum Disorder (ASD) compared with other gold standard measures.
- Trial name
- NCT02668991
- Where
- 9 sites in United States
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Autism
Sensory Adapted Dental Environment to Enhance Oral Care for Children With ASD
The goal of this project is to collect information that will support a later clinical trial on the effectiveness of a specially adapted dental environment for children who have difficulty tolerating oral care in the dental…
- Trial name
- SADE (NCT02077985)
- Testing
- Sensory Adapted Dental Environment
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Autism
FLIGHT - Autism: Education and Health Coaching Program Focused on Modifiable Lifestyle Factors for Parents
The primary purpose of this study is to evaluate the feasibility and effectiveness of an education and coaching program for parents of children with newly diagnosed autism that is focused on modifiable lifestyle factors and…
- Trial name
- NCT07375537
- Testing
- Parent education and coaching program for newly diagnosed autism
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Documenting Hope Project
Autism Spectrum Disorder
Influence of Rhythm and Interpersonal Relationship on Gait Parameters in Children With Autism Spectrum Disorder
Autism Spectrum Disorder (ASD) is associated with differences in social communication, motor coordination, interpersonal synchronization, and gait.
- Trial name
- NCT06659328
- Testing
- Structured Walking Intervention for Children with Autism Spectrum Disorder.
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universidad Europea de Madrid
Transcranial Direct Current Stimulation, Autistic Disorders Spectrum
A Machine Learning Approach for Predicting tDCS Treatment Outcomes of Adolescents With Autism Spectrum Disorders
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by disturbances in communication, poor social skills, and aberrant behaviors.
- Conditions
- Transcranial Direct Current Stimulation, Autistic Disorders Spectrum, Electroencephalography, Machine Learning
- Trial name
- NCT05035511
- Testing
- tDCS
- Where
- Hong Kong
- Volunteers
- 90 people
- Sponsor
- The Hong Kong Polytechnic University
Autism Spectrum Disorder
A Clinical Trial of a New Computer Based Intervention for Children With Autism.
The CLICK-EAST research project is an investigation of the efficacy of a computer based learning programme which aims to teach the fundamental components of social attention to young children with autism spectrum disorder (ASD).
- Trial name
- Click-East (NCT01493609)
- Testing
- Click-East app
- Where
- 2 sites in United Kingdom
- Volunteers
- 54 people
- Sponsor
- University of Edinburgh
Autism Spectrum Disorder
Investigating Social Competence in Youth With Autism
Our treatment, SENSE Theatre, combines several well-documented, effective behavioral strategies and theatre techniques. The proposed project will extend previous findings showing improving improvement in memory for faces.
- Trial name
- NCT03368001
- Testing
- SENSE Theatre, Tackling Teenage Together
- Where
- 3 sites in United States
- Volunteers
- 318 people
- Sponsor
- Vanderbilt University Medical Center
Autism, Autism Spectrum Disorder
A Kinematic Analysis of Motor Planning and Movement Execution of Children With Autism Spectrum Condition
Autism Spectrum Condition (ASC) is a behavioral syndrome characterized by a severe organizational disorder of thinking and major functions that regulate human adaptation.
- Trial name
- NCT06144775
- Testing
- Kinematics measures
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Autism Spectrum Disorder
A Study to Evaluate the Efficacy and Safety of AST-001 in ASD Children
1. Study purpose: To demonstrate the superiority of AST-001 compared to placebo in improving core symptoms of autism spectrum disorder (ASD) in children with ASD. 2.
- Trial name
- NCT06333964
- Testing
- AST-001
- Where
- 11 sites in South Korea
- Volunteers
- 169 people
- Sponsor
- Astrogen, Inc.
Autism or Autistic Traits
Autism Caregiver Coaching in Africa
Around the world there is a growing need to develop early intervention services in local communities that support a better quality of life for all autistic people.
- Trial name
- ACACIA (NCT05551728)
- Testing
- ESDM-informed caregiver coaching
- Where
- South Africa
- Volunteers
- 320 people
- Sponsor
- Duke University
Autism Spectrum Disorder
/Autism Spectrum Disorder(ASD)Hearing Abnormalities Study
Co morbidity rates of hearing loss in children with autism spectrum disorder are high and increasing. Investigators are aiming to: 1.
- Trial name
- NCT03252392
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Autism Spectrum Disorder
Autism, Emotional Processing, and the Amygdala
Empathy imbalance hypothesis suggests that individuals with autism Spectrum Disorder (ASD) should have a deficit of cognitive empathy and a surfeit of emotional empathy.
- Trial name
- NCT04549506
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Yawei Cheng
Autism Spectrum Disorder, Parents
Mindfulness Training and Parent-coaching Interventions for Autism Spectrum Disorder
Caregivers of children with autism spectrum disorder (ASD) report higher levels of depression and distress than caregivers of typically developing children as well as children with other developmental disabilities.
- Conditions
- Autism Spectrum Disorder, Parents, Stress
- Trial name
- NCT03889821
- Testing
- Parent-implemented Early Start Denver Model, Mindfulness Based Stress Reduction
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Vanderbilt University Medical Center
Autism
Safety of L1-79 in Adolescent and Adult Males With Autism
This is a five-arm designed to assess the safety of L1-79 that incorporates 15 prospectively randomized, placebo controlled patients and 5 open label patients at either 100 tid (three times daily) or 200 tid dosing for 28 days.
- Trial name
- NCT02947048
- Testing
- L1-79
- Where
- 2 sites in United States
- Volunteers
- 42 people
- Sponsor
- Yamo Pharmaceuticals LLC
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