Clinical trials: Autism Spectrum Disorders
Autism Spectrum Disorder
Improving Dental Care and Oral Health in Children With Autism Spectrum Disorder
A randomized controlled trial (at sites) comparing the efficacy of the established AIR-P Dental Toolkit (control condition) to a combined regimen involving the Dental Toolkit and parent-mediated behavioral intervention…
- Trial name
- NCT03003221
- Testing
- AIR-P Dental Toolkit, Parent Training
- Where
- 2 sites in United States
- Volunteers
- 119 people
- Sponsor
- University of California, Irvine
Autism Spectrum Disorder
Effect of Probiotic Compound K11T e K11TMax in ASD
The research is characterized as a randomized, double-blind clinical trial (phase III) in which administered the probiotic K11-T (with and without added amino acids, fatty acids and vitamins) to children between 3 and 11 years…
- Trial name
- ASD (NCT06382909)
- Testing
- Inflammatory level, Cognitive assessment, Pedagogical assessment
- Where
- 2 sites in Brazil
- Volunteers
- 505 people
- Sponsor
- Deivis de Oliveira guimaraes
Autism Spectrum Disorder
Use of a Visual Pedagogy and Structure With Children With Autism for Routine Physical Exams
Children with autism spectrum disorders (ASDs) have unique social-communication and behavior impairments that complicate their medical management.
- Trial name
- NCT03232775
- Testing
- Treatment: Physical Exam with Visual Pedagogy and Structure, Control: Physical Exam without Visual Pedagogy and Structure
- Volunteers
- 18 people
- Sponsor
- University of Colorado, Denver
Autism Spectrum Disorder
ACT Combined Yoga for Parental Burnout in Parents with Autistic Children
OBJECTIVE: To explore the intervention effect of ACT combined with a yoga intervention program on parenting burnout in parents with ASD.
- Trial name
- NCT06348992
- Testing
- Acceptance commitment therapy and yoga, Active Comparator: Mental Health Education Group
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Harbin Medical University
Autism Spectrum Disorder, Disruptive Behavior
Iterative Redesign of a Behavioral Skills Training Program for Use in Educational Settings
This study proposes to redesign the RUBI Parent Training program, a low-intensity intervention for youth with autism spectrum disorder and disruptive behavior, for use by school personnel in the classroom.
- Trial name
- NCT04199533
- Testing
- RUBI, RUBIES
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Washington
Autism Spectrum Disorder
Interview TIME: Training Inspired Minds for Employment
The purpose of the study is to see if an internet job interview training program can help people that have autism improve interview skills and access to jobs.
- Trial name
- NCT06291233
- Testing
- Virtual Interview Training (VIT), Services-as-usual
- Where
- 15 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of Michigan
Autism Spectrum Disorders
Single Dose Double-blind, Placebo-controlled Cross-over (SDDBPCCO) Shiftability Study, Will be Followed by a 10-week Open-label Study With Arbaclofen (4 Weeks of Titration and Then 6 Weeks of Active/Stable Treatment). The Effects of Arbaclofen on Target EEG and ERG Metrics Will be Associated With th
study with arbaclofen (4 weeks of titration and then 6 weeks of active/stable treatment). The effects of arbaclofen on target EEG and ERG metrics will be associated with the clinical response in measures of social and general…
- Trial name
- NCT07655115
- Testing
- Arbaclofen
- Where
- 5 sites in France, Spain
- Volunteers
- 103 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
Autism Spectrum Disorder, Anxiety
A Pilot Study of Buspirone for the Treatment of Anxiety in Youth with Autism Spectrum Disorders
The main objective of this exploratory 8-week pilot study is to evaluate the safety and efficacy of buspirone for the treatment of anxiety in youth (ages 6-17 years) with autism spectrum disorders.
- Trial name
- NCT03432065
- Testing
- Buspirone
- Sponsor
- Massachusetts General Hospital
Autism Spectrum Disorder
Real and Virtual Environments in Autism Spectrum Disorder
Individuals with Autism Spectrum Disorder (ASD) are known to have difficulty with socio-communicative functioning and restricted or repetitive behaviors or interests, and there is considerable evidence that the majority also…
- Trial name
- NCT03254992
- Testing
- ASD - Abstract task, ASD - Tangible task, TD - Abstract task
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Autistic Spectrum Disorder, Vestibular Disorder
the Effect of Vestibular Rehabilitation in Autistic Children
This study was conducted to clarify the effect of vestibular education for autistic children on "sensory profile" and "postrotary nystagmus".
- Conditions
- Autistic Spectrum Disorder, Vestibular Disorder, Sensory Integration Disorder
- Trial name
- NCT03957044
- Testing
- The education of sensory integration with vestibular education
- Volunteers
- 22 people
- Sponsor
- Istinye University
Autistic Disorder, Attention Deficit Disorder With Hyperactivity
Atomoxetine Versus Placebo for Symptoms of Attention-Deficit/Hyperactivity Disorder (ADHD) in Children and Adolescents With Autism Spectrum Disorder
The purpose of this study is to determine whether atomoxetine is effective in reducing ADHD (Attention Deficit/Hyperactivity Disorder) symptoms in children and adolescents with ASD (Autism Spectrum Disorder).
- Trial name
- NCT00380692
- Testing
- Atomoxetine
- Where
- 8 sites in Netherlands
- Volunteers
- 97 people
- Sponsor
- Eli Lilly and Company
Autism Spectrum Disorder
Accuracy of Community General Pediatrician Diagnosis of Autism Compared to a Multidisciplinary Team Assessment
The goals of this diagnostic study are to determine how accurate general pediatricians are in autism spectrum disorder (ASD) diagnostic assessment and which children might be best suited for this type of assessment.
- Trial name
- NCT05699928
- Testing
- General pediatrician autism diagnostic assessment, Multidisciplinary team diagnostic assessment, Autism Assessment for Preschoolers with Language Element Sequence
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Autism Spectrum Disorder
Influence of Rhythm and Interpersonal Relationship on Gait Parameters in Children With Autism Spectrum Disorder
Autism Spectrum Disorder (ASD) is associated with differences in social communication, motor coordination, interpersonal synchronization, and gait.
- Trial name
- NCT06659328
- Testing
- Structured Walking Intervention for Children with Autism Spectrum Disorder.
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universidad Europea de Madrid
Transcranial Direct Current Stimulation, Autistic Disorders Spectrum
A Machine Learning Approach for Predicting tDCS Treatment Outcomes of Adolescents With Autism Spectrum Disorders
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by disturbances in communication, poor social skills, and aberrant behaviors.
- Conditions
- Transcranial Direct Current Stimulation, Autistic Disorders Spectrum, Electroencephalography, Machine Learning
- Trial name
- NCT05035511
- Testing
- tDCS
- Where
- Hong Kong
- Volunteers
- 90 people
- Sponsor
- The Hong Kong Polytechnic University
Autism Spectrum Disorder, Anesthesia
Use of an Adaptive Sensory Environment in Autism Spectrum Disorder (ASD) Patients in the Perioperative Environment
The objective of this study is to prospectively examine the preoperative anxiety scores of ASD patients in an adaptive sensory environment.
- Conditions
- Autism Spectrum Disorder, Anesthesia, Procedural Anxiety, Sensory Processing Disorder
- Trial name
- NCT04994613
- Testing
- Sensory adaptive environment
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Dayton Children's Hospital
Autism
Psychophysiological Effects of Lactobacillus Plantarum PS128 in Preschool Children With Autism Spectrum Disorder
Autism Spectrum Disorders (ASD) comprises a complex group of disorders of neuronal development characterized by social and communication impairment along with presence of repetitive and restrictive behaviors.
- Trial name
- NCT03982290
- Testing
- Probiotic, Lactobacillus plantarum PS128
- Where
- Taiwan
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Mackay Memorial Hospital
Typical Development, Obsessive Compulsive Disorder
Developing Brain, Impulsivity and Compulsivity
Background: Impulsivity is acting 'without thinking.' Compulsivity is being overly inflexible. People vary in how impulsive or compulsive they are. Extreme versions of these behaviors play a role in mental disorders.
- Conditions
- Typical Development, Obsessive Compulsive Disorder, Conduct Disorder, Attention Deficit Hyperactivity Disorder
- Trial name
- NCT04631042
- Where
- United States
- Volunteers
- 1,100 people
- Sponsor
- National Institute of Mental Health (NIMH)
Autism Spectrum Disorders
Open Label Extension Study of STX209 (Arbaclofen) in Autism Spectrum Disorders
This is an open-label extension protocol that will provide necessary data on the safety, tolerability, pharmacokinetics and efficacy of STX209 among subjects with ASD.
- Trial name
- NCT01706523
- Testing
- STX209 (arbaclofen)
- Where
- 25 sites in United States
- Volunteers
- 165 people
- Sponsor
- Seaside Therapeutics, Inc.
Autism Spectrum Disorder
Cannabidivarin (CBDV) vs. Placebo in Children With Autism Spectrum Disorder (ASD)
This trial aims to study the efficacy and safety of cannabidivarin (CBDV) in children with ASD.
- Trial name
- NCT03202303
- Testing
- Cannabidivarin
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Montefiore Medical Center
Intellectual Disability
Research and Characterization of New Genes Involved in Intellectual Disability
Intellectual disability (ID) occurs in 2 to 3 % of the general population but the cause is identified only in 30 to 60% of cases.
- Trial name
- GeneDefi (NCT01867554)
- Testing
- gene analysis
- Where
- France
- Volunteers
- 8,500 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
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