Clinical trials: Autism Spectrum Disorders
Autism Spectrum Disorder, Mental Health Issue
Access to Tailored Autism Integrated Care Pilot Study
Children with autism spectrum disorder (ASD) represent a rapidly growing, high-priority clinical population highlighted by the NIMH and Interagency Autism Coordinating Committee due, in part, because they have multiple service…
- Trial name
- ATTAIN (NCT04293627)
- Testing
- ATTAIN
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Autism
Psychophysiological Effects of Lactobacillus Plantarum PS128 in Preschool Children With Autism Spectrum Disorder
Autism Spectrum Disorders (ASD) comprises a complex group of disorders of neuronal development characterized by social and communication impairment along with presence of repetitive and restrictive behaviors.
- Trial name
- NCT03982290
- Testing
- Probiotic, Lactobacillus plantarum PS128
- Where
- Taiwan
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Mackay Memorial Hospital
Autism Disorder, ASD
GENES AND AUTISM - Induced Pluripotent Stem Cells
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by deficits in social interaction and verbal and non-verbal communication (DSM-5, 2013), affecting approximately 2% of the general population.
- Trial name
- IPSC (NCT07311213)
- Testing
- Blood Sample : isolation of peripheral blood mononuclear cells (PBMCs)
- Where
- France
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Autism Spectrum Disorder, Fragile X Syndrome
Speech-in-noise Perception in Autism and Fragile X
The goal of this study is to identify which brain regions are active during speech-in-noise perception, as well as how those regions interact.
- Trial name
- NCT06088589
- Testing
- Mismatch negativity
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Autism Spectrum Disorder
UCB Stem Cells for Autism Spectrum Disorders
Purpose. The goals of the study are to assess the safety of the intravenous infusion of umbilical cord blood (UCB) cells in patients with autism and to confirm changes in social/ communicative skills and cognitive functioning…
- Trial name
- NCT04710810
- Testing
- umbilical cord blood mononuclear stem cells
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- St. Petersburg Bekhterev Research Psychoneurological Institute
Autism Spectrum Disorder
Food Selectivity Protocol for Children With Autism Spectrum Disorders
Food selectivity is a common challenge among children with Autism Spectrum Disorder (ASD), with significant impacts on their nutrition and well-being.
- Trial name
- NCT06179940
- Testing
- Pairwise food selectivity protocol, Individual food selectivity protocol
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Autism Spectrum Disorder, Depression, Anxiety
Developing Mental Health Supports for Autistic Students
The present study aims to expand the availability of emotional supports in order to promote successful transitions and longer-term outcomes for autistic students in PSE.
- Trial name
- NCT04926090
- Testing
- Emotional Support Plan - Clinician Guided (ESP-C), Emotional Support Plan - Self Guided (ESP-S)
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Rutgers, The State University of New Jersey
Autism, Food Allergies
An Autism Study Using Nambudripad's Food Allergy Elimination Treatments
1. We hypothesize that children in the experimental group will show a significant improvement over the control group as all food allergens groups and some other relevant allergenic substances are desensitized in a systematic way…
- Trial name
- NCT00247156
- Testing
- Acupressure treatments and NAET treatments
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Nambudripad's Allergy Research Foundation
Autism Spectrum Disorder
Adapted Judo for Children With Autistic Spectrum Disorders
The project is aligned with one of the overall: To promote social inclusion and equal opportunities, encouraging participation in sport and physical activity.
- Trial name
- AUTJUDO (NCT04523805)
- Testing
- Adapted judo programme
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Ramon Llull
Challenging Behavior, Autism Spectrum Disorder
Measurement of Treatment Effects
The overall objective is to evaluate and compare the efficacy of two common treatments for CB in children and adolescents with autism using multiple outcome measures.
- Trial name
- NCT07024303
- Testing
- Psychotropic medication (at discretion of psychiatrist), Behavioral therapy
- Volunteers
- 20 people
- Sponsor
- Matthew J O'Brien, PhD, BCBA-D
Autism Spectrum Disorder
The Effect of Play on Social and Motor Skills of Children With ASD
In this study, the investigators will compare effects of two types of 8-weeklong interventions: a) multimodal or b) general movement to facilitate social communication and motor skills of school-age children with Autism Spectrum…
- Trial name
- NCT04258254
- Testing
- Multimodal, General, Standard of Care
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Delaware
Language Impairment, Autism
Pilot Evaluation of the Developed Syntactic-Semantic Visual Configuration Intervention for Children With Language Impairment
This study will pilot a newly developed Syntactic-Semantic Visual Configuration Intervention (SSVCI) designed to help Urdu-speaking children with language impairment improve their ability to understand and produce phrases and…
- Conditions
- Language Impairment, Autism, Hearing Impaired Children, Down Syndrome
- Trial name
- SSVC-PILOT (NCT07786545)
- Testing
- Syntactic-Semantic Visual Configuration Intervention (SSVCI)
- Where
- Pakistan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Autism Spectrum Disorder
Effect of a Motor Support Program in Children With Autism
This study examined a motor support program applied for 40 minutes, two days per week, over a period of 12 weeks in children aged 4-6 years diagnosed with autism spectrum disorder.
- Trial name
- NCT07321561
- Testing
- Motor Support Program
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people
- Sponsor
- Istanbul Aydın University
Age 3 to 7 Years, Mild Autism Spectrum
the Effect of Formulation on Anxiety in Autist Childre A Randomized Controlled Trial Assesses Spirulina Syrup Plus Risperidone in Children With Non-idiopathic Autism. Anxiety is Measured Using the SCAS (Parent Version) Via Daily Online Surveys for One Week and Throughout a 3-month Follow-up Period.
The aim of this study is to evaluate the effect of a Spirulina syrup formulation on reducing anxiety in children with non-idiopathic autism.
- Conditions
- Age 3 to 7 Years, Mild Autism Spectrum, no Other Illness or Disorder
- Trial name
- Autism Anxiety (NCT07060872)
- Testing
- Spirulina Syrup, Risperidone
- Where
- Iran
- Volunteers
- 82 people
- Sponsor
- Shahid Sadoughi University of Medical Sciences and Health Services
Cancer, Oncology
Seen and Be Heard: Ensuring Fair Cancer Care for All Children
Introduction: Research has routinely been conducted into the experiences and well-being of children and young people with cancer and their families.
- Conditions
- Cancer, Oncology, Haematological Malignancy
- Trial name
- NCT06481527
- Volunteers
- 50 people
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Autism Spectrum Disorder
Evaluation of the Effect of a Psychological Program for Children With Autism Spectrum Disorder and Feeding Difficulties
Feeding difficulties are frequent in children with Autism Spectrum Disorder (ASD). The main goal of this project was to develop TEAlimento, a behavioral program for children ages 3-8 with ASD and feeding difficulties.
- Trial name
- NCT06108583
- Testing
- TEAlimento : a multicomponent parent training behavioral program to treat feeding difficulties in children with Autism Spectrum Disorder
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Fundació Sant Joan de Déu
Autism
Treatment With Acetyl-Choline Esterase Inhibitors in Children With Autism Spectrum Disorders
We propose a study which will combine multiple modalities in evaluating the treatment response of children with autism spectrum disorders (ASD) to acetyl-choline esterase (AChE) inhibitors and choline supplements.
- Trial name
- NCT01098383
- Testing
- Acetyl-Choline Esterase Inhibitors and Choline supplements
- Where
- Israel
- Volunteers
- 84 people
- Sponsor
- Sheba Medical Center
Pervasive Development Disorders
Guanfacine for the Treatment of Hyperactivity in Pervasive Developmental Disorder
The purpose of this study is to determine whether guanfacine (trade name Intuniv) by itself or in combination with methylphenidate (also known as Ritalin) is helpful for treating hyperactivity in children and adolescents with a…
- Trial name
- NCT01238575
- Testing
- extended-release guanfacine
- Where
- 5 sites in United States
- Volunteers
- 62 people
- Sponsor
- Yale University
CTNNB1 Gene Mutation
Genotype-phenotype Correlations in Children and Adults With CTNNB1 Mutation
The aim of this study is to explore and define the correlations between genotype and phenotype in patients with CTNNB1 mutations as well as monitor and survey the natural history of the CTNNB1 syndrome.
- Trial name
- Gen-Phe CTNNB1 (NCT04812119)
- Testing
- The Modified Checklist for Autism in Toddlers, Revised with Follow-Up (M-CHAT-R/F), The Autism Spectrum Quotient-Children's Version (AQ-Child), The Autism-Spectrum Quotient (AQ)-Adolescent Version (AQ-Adolescent)
- Where
- 3 sites in Australia, Slovenia
- Volunteers
- 100 people
- Sponsor
- University Medical Centre Ljubljana
Autism Spectrum Disorder, Child Safety
ESCAPE Kits for Elopement Prevention in Children With Autism
This study will evaluate elopement prevention kits for children with autism spectrum disorder who exhibit elopement behavior such as dashing or wandering away from safe settings.
- Conditions
- Autism Spectrum Disorder, Child Safety, Caregiver Stress
- Trial name
- NCT07225907
- Testing
- Elopement Prevention Kits
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
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