Clinical trials: Autism Spectrum Disorders
Mental Retardation, Autism Spectrum Disorder
A Cross-sectional Study to Evaluate Speech and Language Development in Chinese Children Aged 2-6 Years
The purpose of this study is to establish a new Chinese children's speech and language norm by obtaining the latest data of speech and language development of children aged 2 ~ 6 from different regions in China.
- Conditions
- Mental Retardation, Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder
- Trial name
- NCT05442229
- Testing
- establish a new Chinese children's speech and language norm
- Volunteers
- 5,744 people
- Sponsor
- Tongji Hospital
Autism Spectrum Disorder
Do Sleep and Circadian Rhythm Disturbances Impact the Cognitive and Behavioural Development of Children With Autism?
The primary objective of this study is to undertake a longitudinal investigation of the impact of sleep and circadian rhythm disturbances on cognitive and behavioural trajectories in children with autism spectrum disorder (ASD)…
- Trial name
- NCT02878499
- Testing
- polysomnography
- Where
- 5 sites in France
- Volunteers
- 105 people
- Sponsor
- University Hospital, Strasbourg, France
Premature Infant
The Early Life Clinical Feature and Risk Factors Analysis in Children With Neurodevelopmental Disorders
The study will be a 5-year retrospective and prospective case control study, included 650 participants, and participants will be divided into four groups.By this research the investigators will achieve several aims:(1) Through…
- Trial name
- NCT05430256
- Where
- Taiwan
- Volunteers
- 650 people
- Sponsor
- Chang Gung Memorial Hospital
Autism Spectrum Disorder
A Study to Evaluate Scales for Repetitive and Restricted Behaviors in Children, Adolescents, and Adults With Autism Spectrum Disorder (ASD)
This is a non-drug study seeking to characterize different scales to measure repetitive and restrictive behaviors in different ASD sub-populations over time. This study will also explore the use of digital biomarkers.
- Trial name
- NCT03611075
- Testing
- No Intervention
- Where
- 18 sites in United States, Canada and 1 more
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Autism Spectrum Disorder, Developmental Language Disorder
Efficacy of a Pragmatic Intervention to Improve Adaptation to Context and Interlocutor
Patients with Developmental Language Disorder (DLD) or Autism Spectrum Disorder (ASD) have communicational difficulties to adapt their language to context and to interlocutors.
- Trial name
- NCT05127863
- Testing
- social communication intervention (pragmatic)
- Where
- Belgium
- Volunteers
- 5 people
- Sponsor
- Université Catholique de Louvain
Autistic Spectrum Disorder
Dates as a Functional Food for Autism
Autism spectrum disorder (ASD) is a lifelong developmental disability that includes deficits in social communication and social interaction and restricted, repetitive patterns of behavior, interests, or activities.
- Trial name
- NCT04261595
- Testing
- Dates fruit as functional Food, behavioral modification and stimulation, nutritional Guidance
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- National Research Centre, Egypt
Autism Spectrum Disorder
Intestinal Microbiota, Tryptophan and Autism
Autism Spectrum Disorder refers to complex neuro-developmental disorders that affect social communication and behavioral adaptation.
- Trial name
- MTA (NCT03751930)
- Testing
- Samples
- Where
- 2 sites in France
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Autism Spectrum Disorder, Disruptive Behavior
Iterative Redesign of a Behavioral Skills Training Program for Use in Educational Settings
This study proposes to redesign the RUBI Parent Training program, a low-intensity intervention for youth with autism spectrum disorder and disruptive behavior, for use by school personnel in the classroom.
- Trial name
- NCT04199533
- Testing
- RUBI, RUBIES
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Washington
Autism Spectrum Disorder
Participant(s) With Autism and High Pain Tolerance Treated With High Dose Naltrexone
High dose naltrexone with response gauged by pain tolerance as measured by the cold pressor test may help treat autism.
- Trial name
- NCT05100563
- Testing
- 50 mg naltrexone
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Autism Spectrum Disorder
Efficacy and Mechanism of rTMS in Children With ASD: an Open-label Clinical Trial
This study is a 6-week open-label clinical trial involving 20 children aged 6-10 years with autism spectrum disorder. During the study, subjects received repeated transcranial magnetic stimulation（rTMS）intervention at the left…
- Trial name
- NCT05238298
- Testing
- repetitive Transcranial Magnetic Stimulation
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Autism Spectrum Disorder
Naturalistic Teaching Strategies in Children With Autism
The study will show the effect of naturalistic teaching strategies and picture exchange communication systems in children with an autism spectrum disorder. There will be two groups in this study.
- Trial name
- NCT05359757
- Testing
- Effect of Naturalistic Teaching Strategies in Children with autism spectrum disorder, PECS Therapy only
- Where
- Pakistan
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Language Delay, Language; Developmental Disorder, Expressive
Intranasal Inhalations of M2 Macrophage Soluble Factors in Children With Developmental Speech Disorders
The investigators have designed an innovative proof-of-concept trial designed to provide data as to whether the speech difficulties in children with developmental dysphasia (DD) are improved with intranasal inhalations of…
- Conditions
- Language Delay, Language; Developmental Disorder, Expressive, Language; Developmental Disorder, Receptive, Autism Spectrum Disorder
- Trial name
- NCT04689282
- Testing
- Bioactive Factors, Produced by M2 Type Macrophages (M2-BFs).
- Where
- Russia
- Volunteers
- 14 people
- Sponsor
- Russian Academy of Medical Sciences
Autistic Spectrum Disorder
Impact of Mixed Reality Training on Motor Skills in Children With Autistic Spectrum Disorder
People with autistic spectrum disorder frequently present impaired motricity, or at least different motricity from neurotypical subjects (walking; postural balance; fine motor skills; motor control, etc.).
- Trial name
- RAMAu (NCT05302544)
- Testing
- Mixed Reality training, motor activities
- Volunteers
- 44 people
- Sponsor
- Université de Reims Champagne-Ardenne
Autism Spectrum Disorder
e-GOLIAH in Autistic Spectrum Disorders
Randomized open-label study comparing children aged 3 to 6 years with autism and normal cognitive development or mild cognitive impairment receiving the usual treatment plus intensive use of eGOLIAH (experimental group) with…
- Trial name
- e-GOLIAH-ECO (NCT05271955)
- Testing
- "e-GOLIAH", Usual care
- Where
- 12 sites in France
- Volunteers
- 150 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Autism Spectrum Disorder
Improving Transition Outcomes for Youth With ASD in a Medicaid Accountable Care Organization
Despite an increasing number of children with Autism Spectrum Disorder (ASD), fragmentation across child and adult service systems results in poor education, employment and health outcomes for transition-aged youth (TAY).
- Trial name
- NCT04869540
- Testing
- Usual care, 'Got Transition' toolkit and resources, PSE intervention
- Sponsor
- Boston Medical Center
Autism Spectrum Disorder
Aquatic Therapy and Autism Spectrum Disorders
To compare the efficacy of one-on-one versus group-based aquatic therapy on the social interactions, behaviors and physical activities of children with autism spectrum disorders (ASDs).
- Trial name
- AT&ASD (NCT03195244)
- Testing
- Aquatic Physical Therapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Sloan W. Rush, MD
Autism Spectrum Disorder
Phenotypic Exploration of Autism Spectrum Disorders Retrospective and Prospective Data
Autism Spectrum Disorders (ASD) are a heterogeneous group of severe developmental abnormalities of the nervous system characterized by deficits in social interaction and verbal and nonverbal communication affecting approximately…
- Trial name
- EXPECT (NCT04923854)
- Testing
- No intervention
- Where
- France
- Volunteers
- 1,500 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Autism Spectrum Disorder
Balance Auditory Vision Training (Bal-A-Vis-X) and Aerobic Training in Children With Autism Spectrum Disorder
the aim of this study is to compare the effects of Rhythmic Balance, Auditory, and Vision Exercises and Aerobic training in children with Autism Spectrum Disorder.
- Trial name
- Bal-A-Vis-X (NCT05013528)
- Testing
- Bal-A-Vis-X training, Aerobic Training Group
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Autism Spectrum Disorder
Intranasal Ketamine With Dexmedetomidine for the Treatment of Children With Autism Spectrum Disorder
Autism spectrum disorder (ASD) is a life-long neurodevelopmental disorder characterized by qualitative abnormalities in reciprocal social interactions and patterns of communication, and by a restricted, stereotyped, repetitive…
- Trial name
- NCT03434366
- Testing
- ketamine and dexmedetomidine, ketamine, Saline
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Guangzhou Women and Children's Medical Center
Autism Spectrum Disorder
Cariprazine Pediatric ASD PK Study
This study will be a multi-center, open-label, parallel-group, multiple-dose study in up to 24 male and female participants aged 5 through 17 years, inclusive, with Autism Spectrum Disorder (ASD).
- Trial name
- NCT04382885
- Testing
- Cariprazine
- Where
- 3 sites in United States
- Volunteers
- 24 people
- Sponsor
- AbbVie