Clinical trials: Autism Spectrum Disorders
Autistic Disorder
Autologous Bone Marrow Stem Cell Therapy for Autism
The aim of this study was to evaluate the safety and effectiveness of autologous bone marrow mononuclear stem cells in the management of autism.
- Trial name
- NCT02627131
- Testing
- Autologous Bone Marrow Mononuclear Cells
- Where
- Vietnam
- Volunteers
- 24 people
- Sponsor
- Vinmec Healthcare System
Autism Spectrum Disorder
Intervention for Toddlers at Risk for Autism Spectrum Disorders (ASD)
This research is being done to test the effectiveness of an early intervention model for very young children at high risk for autism spectrum disorders (ASD) and their families.
- Trial name
- NCT01179841
- Testing
- Playgroup, Parent Training
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Autism, Intellectual Disability
Cognitive-Behavioral Therapy for Irritability in Children With Autism Spectrum Disorder and Intellectual Disability
In addition to the core symptoms, children and adolescents with Autism Spectrum Disorder (ASD) often exhibit disruptive behavior problems including irritability, tantrums, noncompliance, and aggression.
- Trial name
- NCT02914951
- Testing
- Cognitive-Behavioral Therapy, Functional magnetic resonance imaging (fMRI)
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Yale University
Autism Spectrum Disorder, Childhood
Preliminary Exploration of the Usability of a Structured Plate to Improve Eating Behaviors in Children With Autism Spectrum Disorder and Its Impact on the Family: A Pilot Study
This completed single-arm pilot study examined the usability of a structured plate during routine classroom mid-morning snacks in children with autism spectrum disorder and feeding difficulties.
- Conditions
- Autism Spectrum Disorder, Childhood, Feeding Difficulties
- Trial name
- PlaTEA (NCT07516431)
- Testing
- Structured Plate
- Where
- Spain
- Volunteers
- 6 people
- Sponsor
- Universidad de Zaragoza
Avoidant and Restrictive Food Intake Disorders
Avoidant and Restrictive Food Intake Disorders (ARFID) in Adolescence: Early Oral Development, Psychopathological Profile and Sensory Integration
The purpose of this study is to assess if adolescents affected with Avoidant and Restrictive Food Intake Disorders (ARFID) had more frequent precocious pediatric feeding disorders before 4 years old compared to healthy…
- Trial name
- ARFIDOS (NCT06665802)
- Testing
- Questionnaire
- Where
- 3 sites in France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cerebral Palsy Infantile, Pre-Term
Motor-voice Assessment in Infants (MAMI)
The goal of this observational study is to discover features of normal and disordered motor-voice profiles that are biobehavioral markers of physical disability in infants..
- Conditions
- Cerebral Palsy Infantile, Pre-Term, Motor Delay, Neurodevelopmental Disorders
- Trial name
- MAMI (NCT06807203)
- Testing
- Behavioral observation
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Ohio State University
Autism Spectrum Disorder (ASD)
BCI Training for Social Cognition and Error Monitoring in ASD
Social cognition seems to develop atypically in autism, particularly in processes such as faces perception, joint attention and social information processing.
- Trial name
- LEARNAUT (NCT06829303)
- Testing
- Emotional Facial Expression Paradigm (EFP), Speller task
- Where
- Portugal
- Volunteers
- 28 people
- Sponsor
- University of Coimbra
Autism Spectrum Disorder
Examining the Efficacy of the T-STEP
The objective of this study is to evaluate the TEACCH School Transition to Employment and Post-Secondary Education (T-STEP) Program.
- Trial name
- NCT04612231
- Testing
- TEACCH School Transition to Employment and Postsecondary Education (T-STEP), Counseling Services Alone
- Where
- 5 sites in United States
- Volunteers
- 110 people
- Sponsor
- University of North Carolina, Chapel Hill
Autism Spectrum Disorder (ASD)
Double-blind Trial of Buspirone for the Treatment of Anxiety in Youth With Autism Spectrum Disorders
The main objective of this exploratory 8 week pilot study is to evaluate the safety and efficacy of buspirone for the treatment of anxiety in youth (ages 6-17 years) with autism spectrum disorders.
- Trial name
- NCT01395953
- Testing
- Buspirone
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Autism Spectrum Disorder
Combination Treatment for Augmenting Language in Children With ASD
The study will consist of two main elements: the enrollment of 72 children aged 6-11 years with ASD and low language competency to receive a thrice-weekly one hour language intervention for 12 weeks; and, beginning at the same…
- Trial name
- PIII (NCT02574741)
- Testing
- Behavioral Therapy, Aripiprazole
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- University of California, Los Angeles
Autism Spectrum Disorder, Autism
Internet-delivered Cognitive-Behavioral Therapy for Adolescents With Autism and Anxiety
Anxiety is very common in autistic youth. Cognitive behavioral therapy (CBT) is the recommended treatment for both autistic and typically-developing (TD) youth with anxiety, yet most families cannot access CBT due to cost…
- Conditions
- Autism Spectrum Disorder, Autism, Anxiety, Anxiety Disorders
- Trial name
- LUNA-A (NCT06537128)
- Testing
- LUNA-Adolescent, Treatment as Usual
- Where
- United States
- Volunteers
- 139 people
- Sponsor
- Baylor College of Medicine
Autism Spectrum Disorder, Chronic Insomnia
Targeting Sleep in Kids With Autism Spectrum Disorder
Children with Autism Spectrum Disorder (ASD) and insomnia, and their parent(s) will undergo 8 sessions of Cognitive Behavioral Therapy designed for Children with Chronic Insomnia and ASD (CBT-CI-A).
- Trial name
- NCT02755051
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Autistic Spectrum Disorder, Patient Empowerment
Development and Evaluation of "Period Kits" for Adolescents With Intellectual and Developmental Disabilities
This study will involve the development, distribution, and evaluation of "period kits" for pre-menarchal adolescents with intellectual and cognitive disabilities (IDD) (e.g., autism spectrum disorder and Down syndrome) in…
- Conditions
- Autistic Spectrum Disorder, Patient Empowerment, Menstrual Discomfort
- Trial name
- NCT05497167
- Testing
- Period Kit
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tufts Medical Center
Autism Spectrum Disorder
Resources for Optimizing Outcomes in Toddlers on the Spectrum
The goal of this clinical trial is to assess whether telehealth-based Family Navigation (FN) expedites enrollment (e.g., reduces time in days) in community-based autism intervention for toddlers under the age of 4 living in Rural…
- Trial name
- ROOTS (NCT07086781)
- Testing
- Virtual Family Navigation, Educational Materials
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of North Carolina, Chapel Hill
Autism Spectrum Disorder
Acceptability and Outcomes of an Online Parent-Mediated Intervention for Young Autistic Children
This preliminary single-arm pre-post interventional study was designed to evaluate the acceptability and preliminary clinical outcomes of an 8-week online group-based parent-mediated intervention (OYNA) for parents of young…
- Trial name
- NCT07763067
- Testing
- Online Group-Based Parent-Mediated Intervention (OYNA)
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Herguner Therapy Private Clinic
Autism Spectrum Disorder (ASD), Intellectual Disability
Verbal Intent and Gaze Cues on Action Prediction in ASD
A 2×2×3 mixed design (intent word × object type × group: TD, ASD, ID) was used. Age-matched children watched videos and judged which object a model would pick; their choices and eye movements were recorded.
- Trial name
- NCT07597694
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Psychiatric Disorders, Neurodevelopmental Disorders
CYP2D6 Pharmacogenetics in Risperidone-Treated Children
Risperidone is an important medication used to treat children with psychiatric illnesses or neurodevelopmental disorders, such as autism. Despite excellent symptom control, the potential for side effects is worrisome.
- Trial name
- NCT00783783
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Autism, Mental Health Conditions
A Toolkit to Improve Mental Health Treatment for Autistic Individuals
This pilot study is funded by the Organization for Autism Research (OAR). We are conducting a pilot study to improve mental health treatment for autistic individuals.
- Trial name
- NCT07539519
- Testing
- Enhanced Psychotherapy, Treatment as Usual (TAU)
- Where
- 2 sites in United States
- Volunteers
- 18 people
- Sponsor
- Florida International University
Autism Spectrum Disorder, Anesthesia
Observational Prospective Study on Behavioral Outcomes of Children With Autism Spectrum Disorder (ASD) in Comparison to Those Without Neurodevelopmental Diagnoses
Autism Spectrum Disorder (ASD) is the fastest growing neurodevelopmental disorder in the world. Approximately 1% of the population worldwide is affected by this disorder.
- Trial name
- NCT02707939
- Testing
- Observation
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Specific Phobia, Social Anxiety Disorder
Virtual Reality for Youth Phobias
The purpose of this study is to examine the effectiveness of virtual reality (VR) delivered exposure therapy for youth with phobias or social anxiety, with and without autism spectrum disorder.
- Conditions
- Specific Phobia, Social Anxiety Disorder, Autism Spectrum Disorder
- Trial name
- NCT05839431
- Testing
- Virtual Reality for Youth Phobias
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Miami
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