Clinical trials: Autism Spectrum Disorders (ASD)
Autism Spectrum Disorder (ASD)
Evaluate the Efficacy and Safety of TTYP01 Tablets in Adolescents and Children With ASD
This is a multi-center, randomized, double-blind, multiple dose levels, parallal group, placebo-controlled study, to evaluate the safety, PK profiles and preliminary efficacy of TTYP01 tablets in adolescents and children with ASD.
- Trial name
- NCT06757504
- Testing
- TTYP01 Tablets (12mg or 18mg)
- Where
- 5 sites in China
- Volunteers
- 150 people
- Sponsor
- Shanghai Auzone Biological Technology Co., Ltd.
Autism Spectrum Disorder (ASD)
Butyrate Supplementation in Children With Autism Spectrum Disorder (ASD) and Functional Gastrointestinal Disorders
Autism spectrum disorder (ASD) is a neurodevelopmental condition occurring in 1:77 Italian children. Several comorbidities are reported, including functional gastrointestinal disorders (FGIDs) present in up to 70% of patients.
- Trial name
- b(AUT)yrate (NCT06514573)
- Testing
- Sodium Butyrate
- Where
- 3 sites in Italy
- Volunteers
- 128 people
- Sponsor
- Istituto Superiore di Sanità
Autism Spectrum Disorder (ASD
Phase II Clinical Trial to Evaluate the Efficacy and Safety of NV01-A02 in Children With Autism Spectrum Disorder
This is a multicenter, randomized, double-blind, placebo-controlled, therapeutic exploratory Phase 2 clinical trial designed to evaluate the efficacy and safety of NV01-A02 in pediatric participants diagnosed with Autism Spectrum…
- Trial name
- NCT06951854
- Testing
- Drug: NV01-A02
- Where
- South Korea
- Volunteers
- 105 people
- Sponsor
- Neuroventi Inc.
Phelan-McDermid Syndrome, Autism Spectrum Disorder (ASD)
A Controlled Trial of Growth Hormone in Phelan-McDermid Syndrome and Idiopathic Autism
This clinical trial will use growth hormone as a novel treatment for Phelan-McDermid syndrome (PMS) and idiopathic autism. A double-blind, placebo-controlled crossover trial design will be used in 30 children with idiopathic…
- Trial name
- NCT05187377
- Testing
- Growth Hormone, Saline
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Autism Spectrum Disorder (ASD)
Sensory-Motor Integration for Sensory Processing and Balance in ASD
This randomized controlled trial evaluates the effectiveness of a 16-week structured sensory-motor integration exercise program compared to conventional therapy (Applied Behavior Analysis and massage therapy) in improving sensory…
- Trial name
- SMIE-ASD (NCT06922422)
- Testing
- Sensory-Motor Integration Exercises, Conventional therapy group
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Assiut University
Autism Spectrum Disorder (ASD), Neurodevelopmental Disorders
Multi-observational Study for the Early Identification of Autism Spectrum Disorder (ASD) and Other Neurodevelopmental Disorders (NDD) in At-risk Populations
Autism spectrum disorder (ASD) is a neurodevelopmental disorder (NDD) that affects about 78 million people worldwide. Its prevalence and degree of impact on individuals and families place it among disorders of global importance.
- Trial name
- BABY@NET (NCT06915805)
- Where
- 5 sites in Italy
- Volunteers
- 296 people, healthy volunteers welcome
- Sponsor
- Istituto Superiore di Sanità
Autism Spectrum Disorder (ASD)
Omega-3 Fatty Acids Monotherapy in Children and Adolescents With Autism Spectrum Disorders
The primary aim of this study is to examine the efficacy and tolerability of short-term omega-3 fatty acids monotherapy in youth with Autism Spectrum Disorders (ASD).
- Trial name
- NCT01248130
- Testing
- Omega-3 Fatty Acid
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Massachusetts General Hospital
Autism Spectrum Disorder (ASD)
Telehealth Intervention for Infants With Prodromes of ASD
Autism Spectrum Disorder (ASD) is a complex neurodevelopmental disorder characterized by social-communication and interaction deficits and restricted, repetitive patterns of interests and behavior.
- Trial name
- FIRRST (NCT06817746)
- Testing
- FIRRST, Parent Education
- Where
- 4 sites in Italy
- Volunteers
- 132 people
- Sponsor
- IRCCS Fondazione Stella Maris
Autism Spectrum Disorder (ASD)
Evaluation of the Videodrama Therapeutic Device for Children With Autism Spectrum Disorders
Autism spectrum disorder (ASD) is a neurodevelopmental disorder (Valerie, Sperenza, 2009) that begins early in development, characterized by persistent deficits in communication and social interactions across various contexts and…
- Trial name
- VIDEOTSA (NCT06443320)
- Testing
- patient included in experimental groupe will view the video excerpt, a playtime, a drawing activities
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Intercommunal Robert Ballanger
Autism Spectrum Disorder (ASD), Stereotyped Behavior
Efficacy of Physical Activity for the Management of Stereotyped Behavior and Anxiety in Children With Autism Spectrum Disorder
The primary purpose of the study is to investigate whether physical activity can significantly manage stereotyped behavior and anxiety in children diagnosed with Autism Spectrum Disorder (ASD).
- Conditions
- Autism Spectrum Disorder (ASD), Stereotyped Behavior, Anxiety
- Trial name
- NCT06800001
- Testing
- Physical Activity
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Fatima Jinnah Women University
Autism Spectrum Disorder (ASD)
A 12-Week Placebo-Controlled Study to Investigate the Efficacy, Safety, and Tolerability of RO7017773 in Participants Aged 15-45 Years With Autism Spectrum Disorder (ASD)
This study will investigate the efficacy, safety, tolerability, and pharmacokinetics of RO7017773 in participants aged 15-45 years who have been diagnosed with ASD with a score of >/=50 on the Wechsler Abreviated Scale of…
- Trial name
- NCT04299464
- Testing
- RO7017773
- Where
- 21 sites in United States, Canada and 2 more
- Volunteers
- 104 people
- Sponsor
- Hoffmann-La Roche
Asthma in Children, Intellectual Disabilities (F70-F79)
Using a Smart Inhaler to Support Asthma Management in Adolescents With Intellectual and Developmental Disabilities
Correct use of daily medications containing inhaled corticosteroids is key for asthma control, yet children with intellectual and developmental disabilities (IDD) face additional barriers to proper inhaler use.
- Conditions
- Asthma in Children, Intellectual Disabilities (F70-F79), Developmental Disability, Autism Spectrum Disorder (ASD)
- Trial name
- IDD (NCT06783101)
- Testing
- Use of smart inhaler to enhance asthma inhaler proficiency
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Children's Hospital Los Angeles
Autism Spectrum Disorder (ASD
Combination of Supplements for Treating Autistic Spectrum Disorder
A pilot study to compare the efficacy of a combination of apitherapy supplements versus placebo in children with autistic spectrum disorder.
- Trial name
- APITSA (NCT06756711)
- Testing
- A combination of apitherapy and plant extracts
- Where
- 2 sites in Romania
- Volunteers
- 40 people
- Sponsor
- Fundatia Bio-Forum
Autism Spectrum Disorder (ASD)
High Definition Transcranial Direct Current Stimulation of Right Inferior Frontal Gyrus to Improve Social Impairments in Children with Autism
The goal of this clinical trial is to learn if high definition transcranial direct current stimulation (HD-tDCS) of right inferior frontal gyrus works to improve social impairments in children with autism spectrum disorder (ASD).
- Trial name
- NCT06723522
- Testing
- HD-tDCS
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Central South University
Autism Spectrum Disorder (ASD)
Investigation of the Genetic and Environmental Causes of Autism: a Multi-Center Study
The goal of this observational study is to investigate the genetic and epigenetic mechanisms that may contribute to the development of Autism Spectrum Disorder (ASD) in individuals of different age groups.
- Trial name
- ASD-Omics-TR (NCT06662591)
- Where
- 20 sites in Turkey (Türkiye)
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Research and Treatment Society of Genetic Disorders
Autism Spectrum Disorder (ASD), Pain Perception
Quantitative Sensory Testing to Study Pain Perception in Autism
This study aims at assess sensory perception, and pain perception, in neurodivergent children and adolescent in the autism spectrum.
- Trial name
- PPiA (NCT06659731)
- Testing
- Quantitative Sensory testing (QST), EEG
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Autism Spectrum Disorder (ASD), Neurodevelopmental Disorders
Telepsychiatry in Children: Diagnostic Evaluation of Autism Spectrum Disorder
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder recognized as a major national cause in 2012. The French Autism Plan 2018-2022 emphasizes early diagnosis and intervention for better cognitive and behavioral…
- Trial name
- TELE-TSA (NCT06622395)
- Testing
- Remote diagnosys
- Where
- France
- Volunteers
- 137 people
- Sponsor
- Centre Hospitalier St Anne
Autism Spectrum Disorder (ASD)
Impact of AAI Dogs on Performance and Behavior of Children with Autism
Autism Spectrum Disorder (ASD) is a lifelong neurodevelopmental disorder usually diagnosed in early childhood. Children with ASD exhibit social communication and interaction problems, which may cause deficits in social-emotional…
- Trial name
- AAI (NCT06609122)
- Testing
- Animal Assisted Intervention
- Where
- Hong Kong
- Volunteers
- 66 people
- Sponsor
- The University of Hong Kong
Autism Spectrum Disorder (ASD, Parental Behaviors
Effectiveness of Video-feedback for Positive Parenting with Children At Risk of ASD
Improving parent-child interactions benefits child development and parents' perception of their competencies for childrearing and support for child learning and development, which in turns positively impacts on parental emotional…
- Trial name
- VIFEPOPA (NCT06604988)
- Testing
- Video-feedback intervention to promote positive parenting
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- University of Barcelona
Autism Spectrum Disorder (ASD)
Efficacy and Safety of Bumetanide Oral Liquid Formulation in Children and Adolescents Aged From 7 to Less Than 18 Years Old With Autism Spectrum Disorder
The purpose of this study was to evaluate the efficacy and the safety of bumetanide/S95008 in the improvement of Autism Spectrum Disorder core symptoms.
- Trial name
- NCT03715166
- Testing
- Bumetanide Oral Solution
- Where
- 45 sites in Brazil, France and 8 more
- Volunteers
- 211 people
- Sponsor
- Institut de Recherches Internationales Servier