Clinical trials: Autism Spectrum Disorders (ASD)
Obsessive-Compulsive Disorder, Autism Spectrum Disorder
ICBT for OCD in Children With Autism
The purpose of this trial is to evaluate the clinical efficacy, the cost-effectiveness and the effect durability of a therapist-guided, internet-delivered cognitive-behavior therapy intervention for obsessive-compulsive disorder…
- Trial name
- NCT06582225
- Testing
- Internet-delivered exposure and response prevention (I-ERP), Internet-delivered stress management (I-SM)
- Where
- 3 sites in Sweden
- Volunteers
- 220 people
- Sponsor
- Karolinska Institutet
Autism Spectrum Disorder
VGN-Ex05e in Patients With Autism Spectrum Disorder Associated With Severe Self-Injurious and Aggressive Behaviors
To evaluate the safety and tolerability of intracerebral injection of VGN-Ex05e in the nucleus accumbens of patients with autism spectrum disorder.
- Trial name
- NCT07433517
- Testing
- VGN-Ex05e
- Volunteers
- 6 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Autism Spectrum Disorder, Intellectual Disability
Expert Guiding Technology to Help Individuals With Developmental Challenges Build Life and Vocational Skills
Clinical trials will evaluate the efficacy of expert guiding technology to support instructors to better help individuals with developmental challenges due to ASD and ID learn life and vocational skills.
- Trial name
- NCT04518358
- Testing
- Use of Expert Guiding Technology (GAINS) to Improve Live and Vocational Skills for Individuals with Developmental Challenges
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- John T. Nosek
Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder
Eye Tracking as a Predictor of Methylphenidate Response in Autism With ADHD
The overall goal of this research is to use neurophysiological measures to profile strengths and deficits for Attention Deficit Hyperactivity Disorder co-morbidity in Autism Spectrum Disorder to clarify diagnosis and to predict…
- Trial name
- SAT (NCT02874690)
- Testing
- Methylphenidate
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Autism, Autism Spectrum Disorder
Static Balance in Children With Autism vs. Neurotypical Peers
The Virtual Reality Rehabilitation System (VRRS) is an innovative and sophisticated technology, aimed to generate immersive and interactive settings intended for therapeutic and evaluative objectives.
- Trial name
- NCT06152510
- Testing
- Virtual Reality Rehabilitation System
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Autism Spectrum Disorder
Autism ALERT Expansion
Autism Access Link for Early Referral and Treatment [ALERT], the intervention proposed in this application, is a novel state-wide referral and case management platform that PCPs can activate to ensure that a child with suspected…
- Trial name
- NCT06246890
- Testing
- Autism ALERT
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Oregon Health and Science University
Schizophrenia, Schizoaffective Disorder
Second-Generation Antipsychotic Treatment Indication Effectiveness And Tolerability In Youth (Satiety) Study
The purpose of this study is to get a better understanding of the side effect burden and identify predictors of psychotic, mood and aggressive disorders in children and adolescents.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder, Psychotic Disorder, Not Otherwise Specified
- Trial name
- SATIETY (NCT01269710)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of North Carolina, Chapel Hill
Agitation in Adolescents and Young Adults With ASD
INP105 Proof-of-concept Study for the Acute Treatment of Agitation in Adolescents and Young Adults With ASD
This is a Phase 2a, proof-of concept, 2-way, 2-period crossover, double-blind study to evaluate the safety and efficacy of INP105 as an acute treatment versus placebo in adolescents and young adults with autism spectrum disorder…
- Trial name
- CALM 201 (NCT05163717)
- Testing
- INP105
- Where
- 2 sites in United States
- Volunteers
- 8 people
- Sponsor
- Impel Pharmaceuticals
Autism
Testing Swim Instruction for Autistic Children
The goal of this clinical trial is to compare the effects of a specialized swimming and water-safety program (Sensory Enhanced Aquatics) and standard swimming lessons for autistic children.
- Trial name
- NCT06216613
- Testing
- Sensory Enhanced Aquatics, Standard Swim Lessons
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Kansas Medical Center
Efficacy of PEGASUS
Evaluating PEGASUS - a Group Intervention for Young People With an Autism Spectrum Disorder
When a clinician gives an autism spectrum disorder (ASD) diagnosis they hope this will be helpful to the person receiving it and their family.
- Trial name
- NCT01187940
- Testing
- PEGASUS
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Institute of Child Health
Autism Spectrum Disorder
Effectiveness of Social Skills Training Group for Children With Autism Spectrum Disorder
Socio-communicative impairments are core deficits in individuals with autism spectrum disorder (ASD). Individuals with ASD have difficulty understanding eye contact, facial expressions, body language, and different tones of voice…
- Trial name
- NCT04551313
- Testing
- social skill group
- Where
- 2 sites in Taiwan
- Volunteers
- 86 people
- Sponsor
- National Taiwan University Hospital
Sleep Disorder (Disorder), Autism Spectrum Disorder
"Sleep Patterns and EEG Structure in Youth With Autism: Links With Behavior and Parental Stress"
This retrospective observational study is designed to investigate sleep patterns, as well as both the macrostructure and microstructure of sleep, in a large cohort of children and adolescents diagnosed with Autism Spectrum…
- Trial name
- NCT07122388
- Testing
- Questionnaires about autism spectrum disorders and sleep and PSG., ADOS-2, ADI-R, SRS-2, PSG
- Where
- Italy
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- University of Campania Luigi Vanvitelli
Autism Spectrum Disorder, Developmental Disorder
Children's Autism Metabolome Project
Development and Clinical Evaluation of the Stemina Metabolic Biomarker-Based Test to Diagnose Autism Spectrum Disorder in Early Childhood.
- Trial name
- CAMP-01 (NCT02548442)
- Where
- 8 sites in United States
- Volunteers
- 1,102 people, healthy volunteers welcome
- Sponsor
- Stemina Biomarker Discovery, Inc.
Autistic Spectrum Disorder, Constipation
Oral Administration of Polyethylene Glycol (PEG) for 6 Months in Chronically Constipated Autistic Children
Many autistic children suffer from chronic constipation. Gut mobilization was obtained administering polyethylene glycol (PEG) at the dose of 6.9 g/d once a day for 6 months in an open trial involving 21 chronically constipated…
- Trial name
- NCT05025553
- Testing
- Gut mobilization
- Where
- Italy
- Volunteers
- 21 people
- Sponsor
- University of Messina
Autistic Spectrum Disorders
TSO in Pediatric Autistic Spectrum Disorders
The primary objective of this study is to evaluate and compare the safety and efficacy of Trichuris suis ova (TSO) therapy (versus placebo) in pediatric patients with autism.
- Trial name
- TSO (NCT01734941)
- Testing
- TSO
- Where
- Israel
- Volunteers
- 9 people
- Sponsor
- Hadassah Medical Organization
Autism Spectrum Disorder (ASD), Neurodevelopmental Disorders
Multi-observational Study for the Early Identification of Autism Spectrum Disorder (ASD) and Other Neurodevelopmental Disorders (NDD) in At-risk Populations
Autism spectrum disorder (ASD) is a neurodevelopmental disorder (NDD) that affects about 78 million people worldwide. Its prevalence and degree of impact on individuals and families place it among disorders of global importance.
- Trial name
- BABY@NET (NCT06915805)
- Where
- 5 sites in Italy
- Volunteers
- 455 people, healthy volunteers welcome
- Sponsor
- Istituto Superiore di Sanità
Autism or Autistic Traits, Healthy
Development of Prosocial Behaviors and Related Brain Network in Infants of High and Low Risk of ASD
The goal of this observational study is to compare the developmental trajectories of prosocial behaviors and functional network connections in infants and toddlers at high and low risk of autism spectrum disorder (ASD).
- Trial name
- NCT06329245
- Testing
- Do not take any interventions
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Child Autism
Hyperbaric Oxygen Treatment in Autism Spectrum Disorders
Hyperbaric oxygen therapy (HBOT) is part of a multidisciplinary therapeutic management of infant autism including psychotherapy, drug treatment and other therapeutics (speech therapy, occupational therapy restrictive diet ...).
- Trial name
- NCT04472780
- Testing
- Hyperbaric oxygen Therapy HBOT
- Where
- Tunisia
- Volunteers
- 80 people
- Sponsor
- General Administration of Military Health, Tunisia
Attention Deficit Disorder With Hyperactivity, Attention Deficit Disorder
Near Infrared Spectroscopy in Children With Autism and ADHD
Background: Near-infrared spectroscopy (NIRS) is a functional imaging technique that can be uses light to study brain function while allowing for movement.
- Conditions
- Attention Deficit Disorder With Hyperactivity, Attention Deficit Disorder, Attention Deficit Hyperactivity Disorder, Autism
- Trial name
- NCT01730079
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Intellectual Disability, Autism
Enhancing Genomic Laboratory Reports to Enhance Communication and Empower Patients
Current lab reports are designed to communicate results from the laboratory to the provider; they are not designed to be accessible to patients.
- Conditions
- Intellectual Disability, Autism, Multiple Congenital Anomalies
- Trial name
- NCT02504502
- Testing
- enhanced genomic report
- Volunteers
- 52 people
- Sponsor
- Geisinger Clinic
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