Clinical trials: Autistic Disorder
Child Autism
Effect of Modified Dental Visual Aids on Behavior Management During Dental Treatment in Children With Autism Spectrum Disorder
There is a need to find an approach that is appropriate for managing children with Autism Spectrum Disorder in the dental clinic, to manage their behaviour and decrease their anxiety in this research we will apply our modified…
- Trial name
- NCT04576559
- Testing
- Modified dental visual aids, Regular dental visual aids
- Where
- Saudi Arabia
- Volunteers
- 64 people
- Sponsor
- King Abdulaziz University
Autism Spectrum Disorder, Autism
Faecal Microbiota Analysis in Neurotypical and Autism Syndrome Disorder Siblings
This study aims to accurately characterise the gut microbiota composition of faeces of children with ASD and compare it with the gut microbiota composition of their neurotypical siblings.
- Trial name
- FAMILY (NCT05794620)
- Testing
- Stool sample
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- East Suffolk and North Essex NHS Foundation Trust
Posture, Balance
Training Balance Among People With Neurodevelopmental Disabilities
This study is a case control pilot study to investigate the impact of a short-term intervention on training anticipatory postural adjustments in a population of people with neurodevelopmental disabilities.
- Conditions
- Posture, Balance, Cerebral Palsy, Autism
- Trial name
- TAPAS (NCT04293120)
- Testing
- Training with weighted ball
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Hartford
Autism Spectrum Disorder
Integrated Life Skill Training and Executive Function Strategies in Children With ASD
The goal of this clinical trial is to test if using what is called executive function strategies like strategies for improving self-regulation ,strategies for improving planning and problem solving work well when applied within…
- Trial name
- ASD (NCT05829577)
- Testing
- Executive Function Strategies and Training, Daily Life skill training, Sensory Integration /Processing training
- Where
- Qatar
- Volunteers
- 92 people
- Sponsor
- Hamad General Hospital
Autism Spectrum Disorder (ASD)
Investigation of the Genetic and Environmental Causes of Autism: a Multi-Center Study
The goal of this observational study is to investigate the genetic and epigenetic mechanisms that may contribute to the development of Autism Spectrum Disorder (ASD) in individuals of different age groups.
- Trial name
- ASD-Omics-TR (NCT06662591)
- Where
- 20 sites in Turkey (Türkiye)
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Research and Treatment Society of Genetic Disorders
Autism Spectrum Disorder
Combination of Predictive Biomarkers to Increase Diagnostics Efficiency of Autism Spectrum Disorder
Early identification and diagnosis of autism spectrum disorder (ASD) is necessary to promote access to early treatment. Despite the high incidence, in Italy it is estimated that 1 in 77 children (age 7-9 years) (Narzisi et al.…
- Trial name
- NCT05796310
- Testing
- Salivary collection, eye-tracking recorder, neuropsychological assessment
- Where
- Italy
- Volunteers
- 28 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Autism Spectrum Disorders
A Study of a Developmental,Individual-Difference,Relationship-Bases/Floortime Intervention for Children With Autistic
Thirty eight autistic spectrum disorder children age 2-6 years recruited into the study. The new treatment intervention is based on the DIR Model. Parents will be coached at the start and then every 3-4 months for 1 year.
- Trial name
- DIR (NCT00954213)
- Testing
- DIR/Floortime parent intervention
- Where
- Thailand
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Autism Spectrum Disorders, Pervasive Developmental Disorders
An Open-Label Trial of Oxytocin in Adolescents With Autism Spectrum Disorders
This study is an 8-week open-label trial testing oxytocin nasal spray (Syntocinon) as a treatment for social impairment in adolescents with autism spectrum disorders (ASD).
- Conditions
- Autism Spectrum Disorders, Pervasive Developmental Disorders, ASD, PDD
- Trial name
- NCT01931033
- Testing
- Intranasal Oxytocin
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Massachusetts General Hospital
Autism Spectrum Disorder
Neuroimaging of Escitalopram in Autism Spectrum Disorder
The goal of this clinical trial is to evaluate the acute effects of escitalopram (Lexapro®) on select brain networks during task-based functional magnetic resonance imaging (fMRI) in adolescent individuals with autism spectrum…
- Trial name
- NCT06826326
- Testing
- Escitalopram 10mg
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Kathryn Unruh
Autism Spectrum Disorder, Microbiota
Gut-oral Axis Microbiome in Autism Spectrum Disorders
Autism Spectrum Disorder (ASD) is a neurodevelopment disorder characterized by impairment in social interaction, communication, and behavior, as well as sensory challenges.
- Trial name
- NCT05830591
- Testing
- Characterization of the microbiome in oral and fecal samples
- Where
- Italy
- Volunteers
- 86 people
- Sponsor
- IRCCS Burlo Garofolo
Autism, ADHD
Spanish-language Executive Function Intervention for Children With Autism and/or ADHD
The goal of this clinical trial is to learn whether the Spanish-language version of Unstuck and On Target (SL-Unstuck), an executive functioning (EF) intervention, is feasible, acceptable, and effective for Spanish-speaking…
- Trial name
- NCT07084324
- Testing
- Unstuck and On Target
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Colorado, Denver
Autism
Secretin for the Treatment of Autism
Many drugs used to treat autism target specific symptoms, such as hyperactivity and aggressiveness. Few drugs target the core autistic symptoms of impaired social interaction and communication.
- Trial name
- NCT00065962
- Testing
- secretin, synthetic porcine, secretin, biologically derived porcine
- Where
- 2 sites in United States
- Volunteers
- 85 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Physical Inactivity, Sedentary Behavior
ASDactive: An Integrated Theory-based Intervention to Promote Habitual Physical Activity
ASDactive is a theory-based behaviour change intervention aimed at improving the physical activity behaviours of autistic youth.
- Conditions
- Physical Inactivity, Sedentary Behavior, Autism, Autism Spectrum Disorder
- Trial name
- ASDactive (NCT05958680)
- Testing
- ASDactive
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Aberystwyth University
Autism Spectrum Disorder
Tracking Intervention Effects With Eye Tracking
This pilot study examines concurrent and predictive relationships between eye tracking and clinical outcomes during a 16-week behavioral intervention (PRT) for children with ASD.
- Trial name
- NCT02856061
- Testing
- Pivotal Response Treatment
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Yale University
Fragile X Syndrome
Trial of Sertraline to Treat Children With Fragile X Syndrome
This study is a control trial of sertraline (Zoloft) in fragile X syndrome children aged 2 years to 5 years 8 months old. The trial is six months long, and each participant will receive a series of tests at both the beginning and…
- Trial name
- NCT01474746
- Testing
- Sertraline
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Randi J. Hagerman, MD
Cognitive Behavioral Therapy, Autism Spectrum Disorder
Parent-Led Cognitive-Behavioral Teletherapy for Anxiety in Youth With ASD
This study implements an anxiety-focused, parent-led, therapist-assisted cognitive behavioral teletherapy for parents of youth with ASD and anxiety.
- Conditions
- Cognitive Behavioral Therapy, Autism Spectrum Disorder, Anxiety Disorders, Obsessive-Compulsive Disorder
- Trial name
- NCT04111874
- Testing
- Cognitive Behavioral Teletherapy LTA, Cognitive Behavioral Teletherapy STA
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Baylor College of Medicine
Child Development Disorders, Pervasive
Using the Prevent-Teach-Reinforce Model to Reduce Problem Behaviors in Children With Autism Spectrum Disorders
Children with autism spectrum disorders often engage in problem behaviors such as self-injury, destruction, aggression, and stereotypy.
- Trial name
- NCT02153203
- Testing
- Prevent-Teach-Reinforce Model, Individual Parent Training Session
- Where
- 3 sites in Canada
- Volunteers
- 42 people
- Sponsor
- Université de Montréal
Autism Spectrum Disorder, Sleep Disorder
Effect of Snoezelen-Based Occupational Therapy Intervention on Sleep and Behavior Problems in Infant at Risk of Autism
Objective: Sleep and behavioral problems are common in infants at risk of autism. This study aims to examine the effect of Snoezelen-Based Occupational Therapy intervention on sleep and behavioral problems in infants at risk of…
- Conditions
- Autism Spectrum Disorder, Sleep Disorder, Behavior Problem
- Trial name
- NCT06164210
- Testing
- Snoezelen-Based Occupational Therapy Intervention Group
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Ankara University
Autism Spectrum Disorder, Wearable Devices
ASD Wearables Feasibility Study
The goal of this clinical study is to evaluate and compare the feasibility of wearable device use among pediatric participants with autism spectrum disorder (ASD) across four different wearable device form factors: a wristband…
- Trial name
- ASDW (NCT07504224)
- Testing
- 14-Day Device Monitoring
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Rady Pediatric Genomics & Systems Medicine Institute
Epilepsy; Seizure, Neuromuscular Diseases
North Carolina Genomic Evaluation by Next-generation Exome Sequencing, 2
The "North Carolina Clinical Genomic Evaluation by Next-gen Exome Sequencing, 2 (NCGENES 2)" study is part of a larger consortium project investigating the clinical utility, or net benefit of an intervention on patient and family…
- Conditions
- Epilepsy; Seizure, Neuromuscular Diseases, Brain Malformation, Intellectual Disability
- Trial name
- NCGENES2 (NCT03548779)
- Testing
- Pre-visit prep, usual care + exome seq
- Where
- 3 sites in United States
- Volunteers
- 548 people
- Sponsor
- University of North Carolina, Chapel Hill
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