Clinical trials: Autistic Disorder
Autism Spectrum Disorder
Prevalence and Healthcare Consumption of ASD Patients Using French Medico-administrative Data
Autism Spectrum Disorder (ASD) is one of the neurodevelopmental disorders described in the DSM5 (American Psychiatric Association, 2013).
- Trial name
- ECO-TSA (NCT06409728)
- Where
- 2 sites in France
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Autism Spectrum Disorder, Major Depressive Disorder
rTMS for Depression in Young Adults With Autism
The current clinical trial is focused on evaluating the efficacy of rTMS for treatment of depression in youth and young adults (hereafter called transition aged youth, TAY) with autism spectrum disorder (ASD).
- Trial name
- rTMS-MDD (NCT04972136)
- Testing
- Active Bilateral Theta Burst Stimulation
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Centre for Addiction and Mental Health
Autism
Influence of Vitamin D Deficiency on the Development of Autism
The investigators wish to study the effect of Vitamin D on the development of autism in children. The investigators will also investigate the environmental and genetic influences on the level of Vitamin D in children with autism.
- Trial name
- NCT02222311
- Testing
- Blood Samples
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Autism Spectrum Disorder
CASCADE: CAnnabidiol Study in Children With Autism Spectrum DisordEr
This is a randomized, placebo-controlled study but all study participants will receive the active study medication at some point during the study for at least 12 weeks, and some children with receive CBD for the entire study.
- Trial name
- CASCADE (NCT04520685)
- Testing
- Oral cannabidiol 100mg/mL
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- University of Colorado, Denver
Autism Spectrum Disorder, Autism
Early Diagnostic Telehealth Pilot for Moderate- and High-Risk Children: Evaluating Assessment Protocols and Efficiency in Georgia's Early Intervention Program
This pilot study includes children identified as moderate- as well as high-risk for autism spectrum disorder (ASD) within Georgia's Babies Can't Wait (BCW) Early Intervention (EI) program.
- Trial name
- NCT07623759
- Testing
- Early Diagnostic Response Model Expanded
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Emory University
Autistic Disorder
Safety and Effectiveness of D-Cycloserine in Children With Autism
This study will determine the effectiveness of D-cycloserine in reducing symptoms of autism in autistic children.
- Trial name
- NCT00198120
- Testing
- D-cycloserine
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Indiana University
Autism Spectrum Disorder
Approach to Dance for Autism
This study will be a randomized trial that will examine the impact of a recreational ballet program on children with autism spectrum disorder (ASD).
- Trial name
- ADAPT (NCT06424366)
- Testing
- Ballet for All Kids
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
CTNNB1 Gene Mutation
Genotype-phenotype Correlations in Children and Adults With CTNNB1 Mutation
The aim of this study is to explore and define the correlations between genotype and phenotype in patients with CTNNB1 mutations as well as monitor and survey the natural history of the CTNNB1 syndrome.
- Trial name
- Gen-Phe CTNNB1 (NCT04812119)
- Testing
- The Modified Checklist for Autism in Toddlers, Revised with Follow-Up (M-CHAT-R/F), The Autism Spectrum Quotient-Children's Version (AQ-Child), The Autism-Spectrum Quotient (AQ)-Adolescent Version (AQ-Adolescent)
- Where
- 3 sites in Australia, Slovenia
- Volunteers
- 100 people
- Sponsor
- University Medical Centre Ljubljana
Autism
Trial of Propranolol in Adults and Adolescents With ASD and Predictors of Response
The purpose of this study is to explore the effects of propranolol on social interaction, and secondarily on language, anxiety, adaptive behaviors, and global function in high functioning adults and adolescents with autism in a…
- Trial name
- NCT02414451
- Testing
- Propranolol
- Sponsor
- University of Missouri-Columbia
Autism Spectrum Disorder
Motor Support Program for Multidimensional Development in Autistic Children
This mixed-method study evaluated the effects of a 12-week Motor Support Program (MSP) on the multidimensional development of children with autism aged 4-6.
- Trial name
- NCT07121231
- Testing
- Motor Support Program
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul University - Cerrahpasa
Autism Spectrum Disorder, Developmental Delay
A Salivary miRNA Diagnostic Test for Autism
The goal of this study is to validate a panel of miRNAs that distinguish children with autism spectrum disorder (ASD) from their non-ASD peers with a positive MCHAT-R.
- Trial name
- NCT02832557
- Testing
- Salivary collection, Vineland Adaptive Behavior Scale-III Assessment, Medical history questionaire
- Where
- United States
- Volunteers
- 998 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Autism Spectrum Disorder, Gastro-Intestinal Disorder
Microbiota Transplant Therapy for Children With Both Autism Spectrum Disorder and Gastrointestinal Disorders
The investigators propose to investigate Microbiota Transfer Therapy (MTT) for treating patients with Autism-spectrum disorder with Gastrointestinal disorders (constipation, diarrhea, and/or abdominal pain).
- Conditions
- Autism Spectrum Disorder, Gastro-Intestinal Disorder, Constipation, Diarrhea
- Trial name
- NCT06503978
- Testing
- MTP-101P, Vancomycin, Miralax
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Gut-Brain-Axis Therapeutics Inc.
Autism
Use of Eye Tracking to Aid in Autism Risk Detection
The study will use a non-invasive remote eye-tracking system (Eyelink Portable Duo) to acquire a short series of eye-tracking measures.
- Trial name
- RCFET (NCT06471504)
- Testing
- Eyelink Portable Duo
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Indiana University
Autism
Valproate Response in Aggressive Autistic Adolescents
This study will examine the effect of valproate, a medication used to treat seizures and bipolar disorder, on aggressive behavior in children and adolescents with autism.
- Trial name
- NCT00065884
- Testing
- Valproate
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Developmental Disability, Intellectual Disability
Effect of Sensory Adapted Dental Environment on Dental Anxiety of Children With Intellectual and Developmental Disabilities
Children with intellectual/developmental disabilities (ID/DD) will experience less dental anxiety and cooperate better in a Sensory Adapted Dental Environment (modified visual, sensory, and somatosensory stimuli in a regular…
- Conditions
- Developmental Disability, Intellectual Disability, Dental Anxiety
- Trial name
- NCT03218462
- Testing
- Sensory Adapted Dental Environment (SADE)
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Virginia Commonwealth University
Executive Dysfunction, Autism Spectrum Disorder
Intervention-Induced Plasticity of Flexibility and Learning Mechanisms in ASD
This project explores the association between learning and cognitive flexibility by testing whether a cognitive behavioral intervention designed to improve flexibility in ASD changes learning and associated neural activation…
- Conditions
- Executive Dysfunction, Autism Spectrum Disorder, Adolescent Behavior
- Trial name
- NCT05131659
- Testing
- Executive function group therapy
- Where
- 2 sites in United States
- Volunteers
- 64 people
- Sponsor
- Children's National Research Institute
Autism Spectrum Disorder, Neurodevelopmental Disorders
KneuroKnits: Participation and Anxiety in People With Neurological Conditions Participating in a Knitting Group
The reported social benefits of knitting combined with the urgent need for social and activity-based programs in the disability community suggest that a knitting intervention may fill a substantial gap in available programs.
- Conditions
- Autism Spectrum Disorder, Neurodevelopmental Disorders, Acquired Brain Injury, Physical Disability
- Trial name
- NCT04639570
- Testing
- KneuroKnits
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Autism Spectrum Disorder
Dietetic Pattern in Children With Autism Spectrum Disorders
To date, it is well documented that the gut microbiota (GM) influences numerous physiological processes in the healthy "host". The alteration of the composition and function of the intestinal microbiota, commonly referred to as…
- Trial name
- NCT04719923
- Testing
- Children with autism spectrum disorders
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Federico II University
Autism Spectrum Disorder
Study of the Visual Perception During Emotional States on Subjects With an Intrusive Disorder of the Development
The Pervasive Developmental Disorders (PDD) are severe neurodevelopmental disorders, affecting nearly 1% of the general population.
- Trial name
- VisioTED (NCT02827279)
- Testing
- emotional induction
- Where
- France
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Autism Spectrum Disorder
Cognoa ASD Diagnostic Device - Data Collection Study
The primary objective of this study is to collect data to ascertain the PPV and NPV of the current version of the Cognoa diagnostic device.
- Trial name
- NCT03871179
- Testing
- ASD Diagnostic Device
- Where
- United States
- Sponsor
- Cognoa, Inc.
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