Clinical trials: Autistic Spectrum Disorder
Autism, Autism Spectrum Disorder
Online Evaluation of the Diagnostic Accuracy of BlinkLab's Digital Assessments for Autism
This observational study aims to evaluate how patterns of behavioral and sensorimotor responses measured using the BlinkLab Dx1 smartphone application relate to autism diagnoses in children ages 2 to 11.
- Conditions
- Autism, Autism Spectrum Disorder, Autism Spectrum Disorder (ASD), Neurodevelopmental Conditions
- Trial name
- NCT07590973
- Testing
- BlinkLab Dx1, Retrospective Neurodevelopmental Diagnostic Assessment
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Blinklab Limited
Autistic Disorders Spectrum, Child Development
The Effects of a Nurse-led Community-based Sailing Programme on Resilience of School-aged Children With Autism
The goal of this pilot RCT is to evaluate the feasibility and acceptability of the community-based sailing program and to assess the preliminary effects before the main RCT, given the literature on sailing for children with ASD…
- Trial name
- NCT06575244
- Testing
- Community-based sailing, Crafting activities
- Where
- Hong Kong
- Volunteers
- 36 people
- Sponsor
- Chinese University of Hong Kong
Autism Spectrum Disorder, PTSD and Trauma-related Symptoms
TF-CBT for Autistic Youth Pilot Implementation - Open Pilot
Compared to the general population, autistic youth are at increased risk for both exposure to potentially traumatic events and trauma-related symptoms following trauma exposure.
- Conditions
- Autism Spectrum Disorder, PTSD and Trauma-related Symptoms, Autism, Trauma and Stressor Related Disorders
- Trial name
- NCT07420478
- Testing
- Trauma-Focused Cognitive Behavioral Therapy, modified for autistic youth
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Autism, Autism Spectrum Disorder
Work Chat: An Interactive Virtual Workday
Nearly 50,000 youth with autism spectrum disorder (ASD) transition from high school to adult life each year with only 25% of these transition-age youth with ASD (TAY-ASD) getting jobs within 2 years of graduation.
- Trial name
- NCT05565482
- Testing
- Work Chat: An Interactive Virtual Workday
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Michigan
Autism Spectrum Disorder, Obesity, Childhood
Family, Responsibility, Education, Support, and Health for Families With a Child With Autism
The objective of this proposed study is to collect initial efficacy data on a telehealth parent-based behavioral program for children with autism and overweight or obesity (PBT-A), compared with health education (HE).
- Conditions
- Autism Spectrum Disorder, Obesity, Childhood, Autism
- Trial name
- FRESH-A (NCT05741840)
- Testing
- PBT-A, Health Education (HE)
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Autistic Disorders Spectrum, Adhd
Studies of Brain and Body Interaction
The goal of this study is to characterize biophysiolgoical signals as a comprehensive profile of the nervous systems in order to understand interactions between the brain and body, while an individual performs naturalistic…
- Conditions
- Autistic Disorders Spectrum, Adhd, Asperger Syndrome, Alzheimer Disease
- Trial name
- NCT03672266
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rutgers University
Autism, Autism Spectrum Disorder
Promoting Emotional and Autonomic Control Through Guided Breathing Exercises for Emerging Adults With Autism
This study examines the impact of guided breathing exercises on stress and heart rate variability (HRV) in autistic young adults.
- Trial name
- PEACE-A (NCT07238153)
- Testing
- Guided breathing exercise - SPB, Guided breathing exercise - HRV-BF
- Where
- 2 sites in Belgium
- Volunteers
- 68 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Autism, Autism Spectrum Disorder
Cognitive Control and Metacognition Training
95 autistic children (ages 8-11yrs) will be randomly assigned to a novel computer-based Cognitive Control Training combined with Metacognition Coaching or to a comparison group that receives the intervention after a delay.
- Trial name
- CoMeT (NCT06885684)
- Testing
- Cognitive Control Training + Metacognition Coaching
- Volunteers
- 95 people
- Sponsor
- Boston Children's Hospital
Autism Spectrum Disorder, Autism
Autism Spectrum Disorder (ASD) Neurodevelopmental Disorder With Issues Social Behavior, Communication Issues, GI Dysfunction. Study is Multimodal Interventions Targeting These Pathways With cSVF, Stored MSCs, FMT and Diet Modification. Role of Autoimmunity, Gut-brain Issues, & Issues Examined.
Autism spectrum disorder (ASD) is a neurodevelopmental condition with core deficits in social communication and behavior, often accompanied by gastrointestinal (GI) and metabolic dysfunction.
- Conditions
- Autism Spectrum Disorder, Autism, Autism Spectral Disorder
- Trial name
- GARM-Autism (NCT07546942)
- Testing
- Autologous MSC isolation, concentration, and cryopreservation of adult mesenchymal stem cells, Fecal Biomicrome Transplantation (FMT), Ketogenic RESET Diet Protocol
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Black Tie Medical, Inc.
Autism Spectrum Disorder
Participant Database for Autism Research Studies
The purpose of this study is to create a subject database to recruit for current and future studies in research on autism and other neurodevelopmental disabilities.
- Trial name
- NCT00549731
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Autism Spectrum Disorder
Sensory and Connectivity Abnormalities in Autism Spectrum Disorders
Study the neural substrates of autism spectrum disorders using neuroimaging methods such as MEG/EEG/MRI.
- Trial name
- NCT00956579
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Autism Spectrum Disorder, Teacher Training
Implementation of a Teacher Classroom Program to Support Preschool Children With Autism or Developmental Problems
The Incredible Years® "Helping Preschool Children with Autism" (IY-HPCA) program is designed for teachers of children aged 2 to 5 years who have students with autism in their classrooms.
- Conditions
- Autism Spectrum Disorder, Teacher Training, Teacher Skills in Addressing Child Mental Health Problem, Developmental Disorders
- Trial name
- NCT06790199
- Testing
- Incredible Years® "Helping Preschool Children with Autism" program (IY-HPCA)
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fundació Sant Joan de Déu
Autism Spectrum Disorder
Treatment by Therapeutic Body Wraps in Children and Adolescents Suffering From Autism With Severe Injurious Behavior.
Severe injurious behaviors in children with autism spectrum disorder are challenging. First line treatment approaches include behavioral techniques but pharmacotherapy is frequently required despite frequent adverse effects in…
- Trial name
- PACKING (NCT03164746)
- Testing
- Dry sheet Therapeutic body wraps, WET sheet Therapeutic body wraps
- Where
- 13 sites in France
- Volunteers
- 48 people
- Sponsor
- University Hospital, Lille
Autism Spectrum Disorder, Other Neurodevelopmental Disorder
Early Assessment of Autism Through Smart Tablet Gameplay
The primary aim of this study is to compare the diagnostic accuracy of an iPad application (Play.Care assessment) with the current clinical "gold standard" diagnosis for diagnosis of Autism Spectrum Disorder (ASD) in children.
- Trial name
- NCT03438994
- Testing
- Play.Care
- Where
- 2 sites in Sweden, United Kingdom
- Volunteers
- 779 people, healthy volunteers welcome
- Sponsor
- University of Strathclyde
Autism Spectrum Disorder
Genome Environment Microbiome and Metabolome in Autism Study
GEMMA is a multicenter longitudinal observational study that follows children who are genetically at-risk of developing autism for their first three years of life, seeking to identify potential biomarkers predictive of autism…
- Trial name
- GEMMA (NCT04271774)
- Where
- 3 sites in United States, Ireland and 1 more
- Volunteers
- 344 people
- Sponsor
- Massachusetts General Hospital
Autism Spectrum Disorder, Obesity
Mobile Health Intervention for Children With Autism
This study is a randomized clinical trial conducted in China from January 2023 to July 2025. It aims to test whether a mobile health program delivered via WeChat, with or without additional human support, can help improve body…
- Conditions
- Autism Spectrum Disorder, Obesity, Pediatric Overweight
- Trial name
- WeChat-Autism (NCT07514910)
- Testing
- Standard Lifestyle Recommendations, WeChat-Based Mobile Health Intervention, Coach-Facilitated Tele-Group Sessions
- Where
- China
- Volunteers
- 276 people
- Sponsor
- Hunan Normal University
Autism Spectrum Disorder, Autism Spectrum Disorder (ASD)
Intranasal Insulin for Autism Spectrum Disorder in Children and Young Adults Aged 4 to 21 Years
This observational study evaluates the real-world use of intranasal insulin in children and young adults with autism spectrum disorder (ASD) utilizing the ViaNase™ device developed by Kurve Therapeutics.
- Conditions
- Autism Spectrum Disorder, Autism Spectrum Disorder (ASD), Autism Spectrum Disorder High-Functioning, Autism Spectrum Disorder With Absence of Functional Language
- Trial name
- IN-INS-AUT (NCT07521371)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Healing Hope International
Neurodevelopmental Disorders, Autism Spectrum Disorder
Description of the Impact of the Modelo Sentido's® on Adaptive Behaviors in Children With Autism
Knowing the impact of the Modelo Sentido´s® (MS) on the gain of adaptive behaviors in children on the autism spectrum (AS) and other associated neurodevelopmental challenges (ANDC), is essential to improve the quality of life of…
- Conditions
- Neurodevelopmental Disorders, Autism Spectrum Disorder, Adaptive Behaviors
- Trial name
- Sentido´s (NCT06477666)
- Testing
- Sentido's® Model
- Where
- Argentina
- Volunteers
- 24 people
- Sponsor
- Sentido's CAIP & CICI Organización Terapéutica
Williams Syndrome, Autism Disorder
Research on the Molecular Mechanism of Cognitive Differences Between Williams Syndrome and Autism Spectrum Disorder
Williams Syndrome (WS) is a rare neurodevelopmental disorder, usually caused by microdeletions of approximately 26 genes in the long arm (7q11.23) region of chromosome 7.
- Trial name
- WS and ASD (NCT07509879)
- Where
- China
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Qilu Hospital of Shandong University
Autism Spectrum Disorder, Autism
Pilot Trial of Pregnenolone in Autism
This is a research study to examine the tolerability and effectiveness of pregnenolone in individuals with autism. Pregnenolone is a naturally occurring steroid hormone in the brain that has been implicated in treating various…
- Trial name
- NCT02627508
- Testing
- Pregnenolone
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Stanford University