Clinical trials: Autistic Spectrum Disorder
Autism
The Effects of a Clean Room Sleeping Environment on Elemental and Chemical Concentrations in Children With Autism
A child and their parent were asked to participate in a research project that sought to study whether sleeping in a very clean environment for 14 days improved the elimination of chemicals and metals from the child's body.
- Trial name
- NCT02195401
- Testing
- Cleanroom
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- The Children's Institute
Autism, Intervention (Training) Condition
Parent-Mediated Social Cognition Intervention for Young Children With Autism Spectrum Disorder
This study evaluates the efficacy of the Companion Mind-Drawing Cooperative Game Program, a parent-mediated, home-based structured play intervention targeting social cognitive development in young children with autism spectrum…
- Conditions
- Autism, Intervention (Training) Condition, Social Cognition, Cognition Improvement
- Trial name
- PMSC-ASD (NCT07708246)
- Testing
- Companion Mind-Drawing Cooperative Game Program
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Children's Hospital of Fudan University
Autism Spectrum Disorder
Effect of a Casein and Gluten Free Diet in Mexican Children With Autism Spectrum Disorder
Assess the effect of a casein-free and gluten-free diet on gastrointestinal symptoms, clinical variables, and the composition of the intestinal microbiota in Mexican children with autism spectrum disorder.
- Trial name
- NCT06556290
- Testing
- Gluten free and casein free diet
- Where
- Mexico
- Volunteers
- 20 people
- Sponsor
- University of Guadalajara
Autism Spectrum Disorder
Effectiveness of Parent-Mediated Intervention Combined With Positive Behavioral Support on Challenging Behaviors and Parenting Stress Among Children With Autism.
This study aims to evaluate the effectiveness of a parent-mediated intervention combined with Positive Behavioral Support (PBS) in reducing challenging behaviors among children with autism and decreasing parenting stress in South…
- Trial name
- NCT07570550
- Testing
- Parent-Mediated Intervention + Positive Behavioral Support (PMI + PBS)
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Islamia University of Bahawalpur
Autistic Disorder
Diffusion Tensor Imaging in Autism
Using a new and more detailed approach to diffusion tensor imaging (DTI) recently developed in our lab, the investigators hope to learn more about irregularities in the brain that are related to autism.
- Trial name
- NCT00382382
- Testing
- diffusion tensor imaging (DTI)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Autism Spectrum Disorder
Arbaclofen vs. Placebo in the Treatment of Children and Adolescents With ASD (ARBA)
This study will examine the safety and efficacy of arbaclofen vs. placebo on social function in children and adolescents with Autism Spectrum Disorder (ASD).
- Trial name
- ARBA (NCT03887676)
- Testing
- Arbaclofen
- Where
- 4 sites in Canada
- Volunteers
- 90 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Autism Spectrum Disorder, Executive Function
The Effect of Cognitive Orientation Approach on Daily Occupational Performance With Autism Spectrum Disorder
The goal of this clinical trial is by using the Cognitive Orientation Approach on Daily Occupational Performance, which is also supported by the literature and applied by occupational therapists, in children diagnosed with Autism…
- Conditions
- Autism Spectrum Disorder, Executive Function, Patient Participation
- Trial name
- NCT06038435
- Testing
- Cognitive Orientation Approach, Ayres Sensory Integration Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Bezmialem Vakif University
Autism Spectrum Disorder, Visual Rehabilitation
Visual Rehabilitation in Children With Autism Spectrum Disorder and Visual Disorders
Children with autism spectrum disorder (ASD) often have visual problems that add difficulty to social interaction and communication.
- Conditions
- Autism Spectrum Disorder, Visual Rehabilitation, Vision, Social Communication
- Trial name
- NCT07644468
- Testing
- Visual Rehabilitation
- Where
- Taiwan
- Volunteers
- 9 people
- Sponsor
- National Taiwan University Hospital
Autism Spectrum Disorders
Brain Genomics Superstruct Project
The purpose of this study is to explore the effects of genes and genetic variation on brain structure and function. Investigators at Harvard plan to explore the relationship between candidate genes that affect cognitive…
- Trial name
- NCT01552460
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Massachusetts General Hospital
Autism Spectrum Disorder, Obesity
Mobile Health Intervention for Children With Autism
This study is a randomized clinical trial conducted in China from January 2023 to July 2025. It aims to test whether a mobile health program delivered via WeChat, with or without additional human support, can help improve body…
- Conditions
- Autism Spectrum Disorder, Obesity, Pediatric Overweight
- Trial name
- WeChat-Autism (NCT07514910)
- Testing
- Standard Lifestyle Recommendations, WeChat-Based Mobile Health Intervention, Coach-Facilitated Tele-Group Sessions
- Where
- China
- Volunteers
- 276 people
- Sponsor
- Hunan Normal University
Autism Spectrum Disorder
Keep Achieving:The Impact of Group Based Activity Programmes on Children Who Have Autism and Their Families
Participation in structured activities and physical activity (PA) have been linked to several indicators of positive development such as self-esteem and psychological health as well as greater academic outcomes and lower school…
- Trial name
- NCT04165655
- Testing
- Keep Achieving (KA)
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- Midlands Psychology CIC
Autism Spectrum Disorders
Handheld Technology for Speech Development in Students With Autism
The proposed study will result in a software application compatible with the Apple iPad, iPhone and iPod Touch (hereafter termed "iOS devices") which addresses several aspects of prosodic deficits common in speakers with Autism…
- Trial name
- NCT01780090
- Testing
- iPad software
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Yale University
Autism Spectrum Disorder
Effect of PLAY Project Intervention Program on Children With ASD
The objective of this study is to evaluate the effectiveness of the Play and Language for Autistic Youngsters (PLAY) Project Home Consultation model to improve parent-child interaction, child development, and autism…
- Trial name
- NCT05531669
- Testing
- PLAY Project, Parental Education
- Where
- 5 sites in China
- Volunteers
- 200 people
- Sponsor
- Tongji Hospital
Tuberous Sclerosis Complex
Early Biomarkers of Autism in Infants With Tuberous Sclerosis Complex (TSC)
The investigators are enrolling 3-12 month old infants with a diagnosis of tuberous sclerosis complex (TSC) for a new study on early markers of autism.
- Trial name
- NCT01780441
- Where
- 5 sites in United States
- Volunteers
- 166 people
- Sponsor
- Boston Children's Hospital
Autistic Disorder
e-Unstuck:Interactive e-Learning Software for Parents to Support Executive Functioning and Behavior Regulation in Children With Autism Spectrum Disorder
The goal of this project is to develop and test e-Unstuck, an e-learning intervention that (1) provides advanced training to parents of children with Autism Spectrum Disorder without Intellectual Disability (ASDwoID) on how to…
- Trial name
- e-Unstuck (NCT02708069)
- Testing
- e-Unstuck, Unstuck and On Target
- Where
- 2 sites in United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- 3-C Institute for Social Development
Autism Spectrum Disorder (ASD), Attention Deficit Hyperactivity Disorder (ADHD)
Physiotherapy for Improving Mental Health in Children and Adolescents With ASD and ADHD
This study investigates whether a structured physiotherapy program can help reduce symptoms of stress, anxiety, and depression in children and adolescents diagnosed with Autism Spectrum Disorder (ASD) or…
- Conditions
- Autism Spectrum Disorder (ASD), Attention Deficit Hyperactivity Disorder (ADHD), Neurodevelopmental Disorders
- Trial name
- NCT07231354
- Testing
- Structured Physiotherapy Program
- Where
- Greece
- Volunteers
- 117 people
- Sponsor
- International Hellenic University
Autism
Secretin for the Treatment of Autism
Many drugs used to treat autism target specific symptoms, such as hyperactivity and aggressiveness. Few drugs target the core autistic symptoms of impaired social interaction and communication.
- Trial name
- NCT00065962
- Testing
- secretin, synthetic porcine, secretin, biologically derived porcine
- Where
- 2 sites in United States
- Volunteers
- 85 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Autism Spectrum Disorder
Social Information Processing in Children: an ocUlo-pupillometric Tool for Standard Evaluation
The goal of this observational study is to identify behavioral and physiological markers of social alterations in Autism Spectrum Disorders compared to Typically Developping peers.
- Trial name
- SIRCUS (NCT05596331)
- Testing
- eye-tracker
- Where
- France
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Autism Spectrum Disorder, Social Anxiety
Using Virtual Reality to Treat Social Anxiety in Autistic Adolescents
This study will test the feasibility and acceptability of virtual reality assisted cognitive behavioural therapy for the treatment of social anxiety in autistic adolescents.
- Trial name
- NCT04301141
- Testing
- Virtual Reality Assisted Cognitive Behavioural Therapy
- Where
- 3 sites in United Kingdom
- Volunteers
- 5 people
- Sponsor
- King's College London
Autism Spectrum Disorder (ASD)
Exercise Efficacy on Autism Spectrum Disorder
The goal of this clinical trial is to learn if regular exercise intervention may improve the health status of the participants diagnosed with autism spectrum disorder, ages between 5-13 years old.
- Trial name
- NCT06831188
- Testing
- daily life exercise group, specific type exercise group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul University