Clinical trials: Automation
Diagnosis
Automation Bias in Physician-LLM Diagnostic Reasoning
This study aims to systematically measure the extent and patterns of automation bias among physicians when utilizing ChatGPT-4o in clinical decision-making.
- Trial name
- NCT06963957
- Testing
- ChatGPT-4o Recommendations with Hallucinations
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Lahore University of Management Sciences
Coagulation Disorder, Blood, Prolonged APTT
External Multicenter Validation of the APTTO Model for Prolonged APTT Using Clot Waveform Analysis
Prolonged activated partial thromboplastin time (APTT) is a frequent laboratory finding that may reflect a broad spectrum of underlying conditions, ranging from benign laboratory abnormalities to clinically relevant hemostatic…
- Trial name
- APTTO-EXT (NCT07418099)
- Testing
- Clot waveform analysis-based risk stratification (APTTO models)
- Where
- 16 sites in Spain
- Volunteers
- 1,500 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
AI Agent
AI-Agent for Automated Diagnosis and Predicting Using EHR and Multimodal Data
The goal of this clinical study is to evaluate the effectiveness of an AI agent in diagnosing and predicting diseases using electronic health records (EHR) and multimodal imaging data.
- Trial name
- NCT06791499
- Where
- 6 sites in China
- Volunteers
- 2,000,000 people, healthy volunteers welcome
- Sponsor
- The Eye Hospital of Wenzhou Medical University
Physician Behavior
Child Health Improvement Through Computer Automation (CHICA) Highlighting Study
The investigators have developed a novel decision support system for implementing clinical guidelines in pediatric practice. CHICA (Child Health Improvement through Computer Automation) combines three elements: (1) pediatric…
- Trial name
- NCT01583101
- Testing
- Receiving Highlighted Prompts, Receiving Non-highlighted Prompts
- Where
- United States
- Volunteers
- 2,237 people, healthy volunteers welcome
- Sponsor
- Indiana University
Mobility Impairment, Clinical Workflow Optimization
Deployment and Evaluation of Humanoid Robotics in Coalition-Aligned Clinical Care Settings
This clinical trial evaluates the deployment of humanoid robotics in coalition-aligned healthcare settings. The study measures biometric performance, ESG compliance, and operational impact across patient care, sanitation, and…
- Conditions
- Mobility Impairment, Clinical Workflow Optimization, Sanitation Protocol Compliance, ESG-linked Healthcare Robotics Deployment
- Trial name
- HEALTH (NCT07214896)
- Testing
- Skin Cell Dip, Stem Cell Dip, Wage Token Distribution
- Where
- 4 sites in United States, Germany and 1 more
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.
Type 1 Diabetes Mellitus
Assess the Efficacy of the Low Glucose Suspend (LGS) Feature in the MiniMed Paradigm® X54 System
The purpose of this study is to assess the efficacy of the Low Glucose Suspend (LGS) feature in reducing hypoglycemia with the MiniMed Paradigm® X54 System with hypoglycemic induction from exercise.
- Trial name
- NCT01148862
- Testing
- The MiniMed Paradigm® X54 System
- Where
- 5 sites in United States
- Volunteers
- 50 people
- Sponsor
- Medtronic MiniMed, Inc.
Artificial Intelligence (AI) in Diagnosis, Decision Making
Training Diagnostic Specialists to Use Artificial Intelligence Safely: The DISCORD-Dx Study
This randomized study evaluated whether a structured reasoning strategy called DISCORD-Dx could help specialist doctors use artificial intelligence (AI) recommendations more safely during diagnostic decision-making.
- Trial name
- DISCORD-Dx (NCT07844889)
- Testing
- DISCORD-Dx Training, Conventional AI-Literacy Training
- Where
- Pakistan
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Sara Reza
Kidney Transplant Rejection, Pathology
Development and Validation of a Comprehensive Classification Automation System for Kidney Allograft Biopsies
Since 1991, the Banff classification has been the gold standard for defining antibody-mediated rejection (AMR) and T-cell mediated rejection (TCMR), thereby guiding the treatment and management of transplant recipients.
- Trial name
- NCT05306795
- Where
- France
- Volunteers
- 4,000 people
- Sponsor
- Paris Translational Research Center for Organ Transplantation
Diagnosis
Mitigating Automation Bias in Physician-LLM Diagnostic Reasoning Using Behavioral Nudges
The goal of this randomized controlled trial is to evaluate whether behavioral nudges can reduce automation bias, the uncritical acceptance of automated output, in physicians using large language models (LLM) like ChatGPT-5.1 for…
- Trial name
- NCT07328815
- Testing
- Behavioral Nudge Intervention
- Where
- Pakistan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Lahore University of Management Sciences
COVID-19
FAst and SimplE COVID-19 Causing Virus SARS-CoV-2 Detection
Observational study using biological material. The group of subjects in the study is represented by 100 male and female patients hospitalized with COVID-19 symptomatology and 100 non-hospitalized subjects with suspected COVID-19…
- Trial name
- FASE2 (NCT05341635)
- Testing
- Swab sampling
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- University of Milano Bicocca
Neurologic Disorder
Child Health Improvement Through Computer Automation - Child Neurology (CHICA-CN) Evaluation
The study will evaluate a computer decision support system for child neurology, Child Health Improvement through Computer Automation - Child Neurology (CHICA-CN) using patient chart review, family phone surveys, and physician…
- Trial name
- NCT05173506
- Testing
- Computer decision support for physician
- Where
- United States
- Volunteers
- 455 people
- Sponsor
- Wake Forest University Health Sciences
Bronchiolitis
Automation Oxygen Flow Titration in Spontaneously Breathing Infants
The objective of this study is to assess the efficacy of the FreeO2 device in shortening the hospital length of stay during a first episode of hypoxemic bronchiolitis in infants less than 1 year of age.
- Trial name
- FreeO2Bronchio (NCT03614507)
- Testing
- FreeO2 (modèle FO2-220-00) automatic oxygen flow titration, FreeO2 (modèle FO2-220-00) manual oxygen flow titration
- Where
- 10 sites in France
- Volunteers
- 105 people
- Sponsor
- University Hospital, Brest
Type 1 Diabetes
Outpatient Study to Evaluate Safety and Effectiveness of the Low Glucose Suspend Feature
Introduction: The purpose of the pivotal In Home study is to collect clinical data on the safety and efficacy of the Paradigm LGS System in the actual use environment and by the intended use population.
- Trial name
- ASPIRE (NCT01497938)
- Testing
- Medtronic MMT-754 Veo Insulin pump testing Low Glucose Suspend (LGS) feature, Medtronic (NO LGS FEATURE ) using Paradigm® Revel™2.0 Pump
- Where
- 17 sites in United States
- Volunteers
- 247 people
- Sponsor
- Medtronic MiniMed, Inc.
Type 2 Diabetes
Computer Automation for Diagnosis and Management of Childhood Type 2 Diabetes
Increasing rates of type 2 diabetes among children and adolescents has considerable long-term implications not only for the affected individuals, but also for society and the health system as a whole.
- Trial name
- NCT01814787
- Testing
- CHICA Type 2 Diabetes Module
- Where
- United States
- Volunteers
- 1,369 people
- Sponsor
- Indiana University
Constipation, Encopresis
Child Health Improvement Through Computer Automation of Constipation Management in Primary Care
This project seeks to expand an existing computerized decision support system used in pediatric primary care. The expanded system will add a module that helps clinicians recognize constipated children and then provides…
- Trial name
- CHICA-GI (NCT02354820)
- Testing
- Evidence Based Constipation Reminders
- Volunteers
- 16,264 people
- Sponsor
- William E. Bennett, Jr.