Clinical trials: Axial Length
High Myopia, Refractive Errors
Repeated Low-Level Red-Light Therapy for Shortening Axial Length
The purpose of this clinical trial is to confirm the incidence and magnitude of axial length shortening after RLRL therapy in Chinese high myopia children and teenagers.
- Conditions
- High Myopia, Refractive Errors, Eye Diseases
- Trial name
- NCT05550740
- Testing
- RLRL
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Progressive Myopia
MAD Trial: Myopia Atropine Dose
The goal of this interventional study is to compare the efficacy of Atropine 0.05% to Atropine 0.5% treatment against progression of axial length in European children with progressive myopia, and to evaluate the safety…
- Trial name
- MAD (NCT05667454)
- Testing
- Atropine Ophthalmic 0.05%, Atropine Ophthalmic 0.5%
- Where
- 20 sites in Netherlands
- Volunteers
- 550 people
- Sponsor
- Erasmus Medical Center
Refractive Errors
Clinical Validation Study Protocol for SmartEyes Smart Optometry Measurement Device (Medical Device Clinical Validation Study)
This study aims to evaluate the SmartEyes smart refraction measurement device in two phases under real outpatient optometry room visits at Wuhan Children's Hospital.
- Trial name
- CVSP-SOMD (NCT07803094)
- Testing
- SmartEyes smart refraction measuring device, Topcon KR800, Subjective refraction
- Volunteers
- 200 people
- Sponsor
- The Hong Kong Polytechnic University
Myopia
Myopia Control Effect of DIMS Spectacle Lenses in Czech Children and Young Adults
The aim of this clinical study is to compare the efficacy of DIMS technology spectacle lenses with conventional single vision spectacle lenses at slowing the progression of myopia in the category of children and young adults…
- Trial name
- NCT05943912
- Testing
- Single Vision Spectacle Lens, Defocus Incorporated Multiple Segments (DIMS) Spectacle Lens
- Where
- Czechia
- Volunteers
- 80 people
- Sponsor
- Czech Technical University in Prague
Soft Contact Lens
Soft Peripheral Contact Lens for Eye Elongation Control (SPACE):1-year Results of a Double-blinded Randomized Con-trolled Trial
A prospective, randomised, double-blinded clinical trial was conducted including 115 children (55 male and 60 female) aged 8 to 15 years.
- Trial name
- NCT05733884
- Testing
- soft contact lens
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
Aqueous Tamponade, Cataract
Influence of Intravitreal Aqueous Tamponade on Lens Status and Ocular
To observe the effects of vitreous cavity Balanced salt solution (BSS) tamponade on the state of the lens and related parameters of the eye, and whether the changes of the above parameters are correlated with age, gender…
- Trial name
- NCT06133660
- Testing
- pars plana vitrectomy
- Where
- China
- Volunteers
- 21 people
- Sponsor
- Bo Jia
Myopia
A Controlled Evaluation of Optical Defocus Parameters on Transient Changes in Axial Length Using Kubota Glass
This study will assess the optimal performance characteristics of optical defocus on transient changes in axial length with Kubota Glass, using a randomized, double-masked, 5-treatment, 5-period crossover design with…
- Trial name
- NCT07686289
- Testing
- KG1, KG2, KG3
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Kubota Vision Inc.
Myopia Progressing
Comparison of MiSight 1-Day and Acuvue Oasys for Presbyopia in Myopic Children
This study will compare the effects on myopia progression over the course of one year for eyes wearing MiSight 1 Day contact lenses compared to ACUVUE OASYS for PRESBYOPIA contact lenses.
- Trial name
- MALCOLM (NCT06887920)
- Testing
- Acuvue Oasys for Presbyopia, MiSight 1 Day
- Where
- Australia
- Volunteers
- 72 people
- Sponsor
- Pauline Kang
Myopia, Myopia Progression
The P.A.U.S.E.® Spectacle Study
The goal of this clinical trial is to learn if spectacle lenses using Phase Alteration Utilising Sub Elements (P.A.U.S.E.®) technology works to slow down the rate of myopia progression in myopic children.
- Trial name
- NCT06577948
- Testing
- Single vision spectacle lens, P.A.U.S.E. spectacle lens 1, P.A.U.S.E. spectacle lens 2
- Where
- Vietnam
- Volunteers
- 205 people
- Sponsor
- nthalmic Pty Ltd
Myopia
Wearing Behavior and Eye Length Changes in Children With Myopia Wearing Myopia Control Spectacle Lenses
The goal of this clinical trial is to learn how children with myopia aged 8 to 15 years move their eyes and heads during near-vision tasks while wearing different spectacle lenses, and if wearing myopia control spectacle lenses…
- Trial name
- NCT07780851
- Testing
- Single Vision Lens (SVL), Myopia Control Lens (MCL)
- Where
- Singapore
- Volunteers
- 20 people
- Sponsor
- Essilor International
Myopia
Comparison of Efficacy Between Two Myopia Control Lenses
This is a one-year, mono-centre, randomize, double-masked, monocular cross-over clinical trial designed to test and compare the efficacy of the new lens design in slowing down the increase of axial length and controlling myopia…
- Trial name
- NCT06148870
- Testing
- Myopia Control Lens-1 (MCL1), Myopia Control Lens-2 (MCL2)
- Where
- Singapore
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Essilor International
Hyperopia, Refractive Error
Optical Defocus to Stimulate Eye Elongation in Hyperopia
Axial hyperopia results when the length of the eye is too short for the eye to properly focus distance objects on the retina while the focusing system is relaxed.
- Trial name
- ODSEEH (NCT00950924)
- Testing
- Simultaneous Vision Bifocal Soft Contact Lenses, Single Vision Soft Contact Lenses
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Aller, Thomas A., OD
Myopia Progression, Atropine
Efficacy and Safety of 0.01%, 0.03%, and 0.05% Atropine Eye Drops in Reducing Myopia Progression
Myopia is one of the fastest-growing ocular disorders worldwide and has become a major public health concern, especially among children and adolescents.
- Trial name
- NCT07626892
- Testing
- Atropine sulphate eye drop 0.01%, Atropine sulphate eye drop 0.03%, Atropine sulphate eye drop 0.05%
- Where
- Pakistan
- Volunteers
- 95 people
- Sponsor
- Khyber Medical College, Peshawar
Axial Length, Eye, Myopia
Study on the Impact of Desk and Chair Adaptation Intervention on the Occurrence and Development of Myopia in Primary School Students
This study is a randomized controlled trial of a desk and chair adaptation intervention involving primary school students and their parents or primary caregivers.
- Conditions
- Axial Length, Eye, Myopia, Myopia Progression
- Trial name
- NCT06623760
- Testing
- Desk and chair adaptation interventions
- Volunteers
- 2,100 people, healthy volunteers welcome
- Sponsor
- Fangbiao Tao
Children, Hyperopia
Efficacy of S.T.O.P®KIT in Retarding Axial Length Growth in Children With Low Hyperopia
This is a multicenter, parallel-group, open-label, randomized controlled, superiority interventional clinical study initiated by investigators from Shanghai General Hospital (Study Protocol No.: IT-CRU-FAMB-001, Version V1.1…
- Trial name
- NCT07401511
- Testing
- Attaching different phase Dynamic Spatiotemporal Optical Films (S.T.O.P® KIT) when wearing spectacle frames
- Where
- 3 sites in China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Myopia
The Beijing Childhood Eye Study
Axial myopia has emerged as the leading cause of irreversible vision loss in East Asia, driven by its progression to sight-threatening complications including myopic macular degeneration, retinal detachment, open-angle glaucoma…
- Trial name
- BCES (NCT06931444)
- Where
- China
- Volunteers
- 3,760 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Myopia Progression, Axial Length, Eye
Low Dose Atropine Eye Drops in Myopic Egyptian Children
Previous Studies reported that low concentration atropine eye drops may be effective in increasing the choroidal blood flow and thickness and this slows myopia progression.
- Conditions
- Myopia Progression, Axial Length, Eye, Sclera Thickness
- Trial name
- LAMP (NCT06265454)
- Testing
- low dose atropine eye drops
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Ain Shams University
Myopia, Left Eye
Short Term Refractive and Ocular Parameter Changes After Topical Atropine
In order we had designed a prospective clinical trial. Spherical equivalent refractive error (SER), axial length (AL), mean keratometric value (Mean-K), anterior chamber depth (ACD), and intraocular pressure (IOP) were measured…
- Trial name
- NCT03839888
- Testing
- 0.125% Atropine
- Volunteers
- 96 people
- Sponsor
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Myopia, Myopia, Progressive
Myopia Progression With a Novel Extended Depth of Focus Contact Lens
Myopia has been increasing in prevalence and severity throughout the world over the last 30 years. Increasing levels of myopia are associated with increased frequencies and severity of various ocular pathologies, including…
- Trial name
- NCT03358862
- Testing
- NaturalVue Multifocal Contact Lens
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Aller, Thomas A., OD
Strabismus
Basic Intermittent Exotropia and Risk Factors for Postoperative Overcorrection and Under Correction
To evaluate preoperative risk factors for overcorrection and undercorrection following surgery for basic intermittent exotropia such as axial length of the globe, refractive error, age and sex
- Trial name
- NCT03153423
- Testing
- Strabismus surgery
- Where
- Egypt
- Volunteers
- 86 people
- Sponsor
- Minia University