Clinical trials: Behavior And Behavior Mechanism
Asthma in Children, Dyspnea; Asthmatic
Mechanisms for Dyspnea on Exertion in Children With Obesity and Asthma: Distinct Physiological Phenotypes
The overall objective of this study is to better understand the respiratory mechanisms provoking dyspnea on exertion in obese asthmatic children.
- Conditions
- Asthma in Children, Dyspnea; Asthmatic, Obesity, Childhood
- Trial name
- NCT04184609
- Testing
- Control, Albuterol
- Where
- United States
- Sponsor
- Ohio State University
Helmets, Children
Children's Attitude Towards Helmet Use in Traffic.
SUMMARY Rationale: Literature shows that helmet use is essential in the prevention of severe head injuries among children involved in bicycle accidents. However, helmet use in children remains low.
- Conditions
- Helmets, Children, Behavior And Behavior Mechanism
- Trial name
- ChildHELMED (NCT06490042)
- Testing
- Questionnaire
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Myocardial Injury
Myocardial Physiology And Microanatomy In Individuals Undergoing Heart Surgery
The main focus of the project is to determine to what degree myocardial energy metabolism is linked to impaired function in human cardiomyocytes, whether exercise training and remote ischemic preconditioning can restore…
- Trial name
- TRIMRIPC (NCT01308138)
- Testing
- Exercise training, remote ischemic preconditioning
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Norwegian University of Science and Technology
Behavior and Behavior Mechanisms
Evaluating a Digital Health Information Tool
The primary aim of the proposed project is to conduct a randomized controlled trial to evaluate the efficacy of a digital intervention tool that enables young people to correspond with trained staff via online chat or text…
- Trial name
- Chat/Text (NCT02549599)
- Testing
- Chat/Text Program, Website Content, Delayed Treatment
- Where
- United States
- Volunteers
- 5,220 people, healthy volunteers welcome
- Sponsor
- New York University
Depression in Adolescence
Inflammatory and Glutamatergic Mechanisms of Sustained Threat in Adolescents With Depression
Despite the prevalence and significant public health concern over depression among adolescents, up to 40% of depressed adolescents do not respond to first-line antidepressants (herein termed treatment non-response, TNR).
- Trial name
- TIGER (NCT05329441)
- Testing
- Trier Social Stress Test (TSST)
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- University of California, Los Angeles
Attention Deficit Hyperactivity Disorder
Visual Focused Play Intervention for Children With ADHD
This is a single-center, randomized, double-blind, sham-controlled study that will recruit children with attention deficit hyperactivity disorder and randomly assign them to a test group and a control group.
- Trial name
- NCT06140979
- Testing
- Playing the game, Watching the gameplay video
- Volunteers
- 40 people
- Sponsor
- Xijing Hospital
Prader-Willi Syndrome, Aggression
Guanfacine Extended Release for the Reduction of Aggression and Self-injurious Behavior Associated With Prader-Willi Syndrome
This is a placebo-controlled clinical trial to assess whether Guanfacine Extended Release (GXR) reduces aggression and self injurious behavior in individuals with Prader Willi Syndrome (PWS).
- Conditions
- Prader-Willi Syndrome, Aggression, Self-Injurious Behavior, Pathologic Processes
- Trial name
- PWS-GXR (NCT05657860)
- Testing
- Guanfacine Extended Release
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Maimonides Medical Center
Sudden Cardiac Death
CIQTP Prolongation : Role and Mechanism in Sudden Cardiac Death
Despite major progress in molecular and phenotypic characterization of primary electrical disorders, many (aborted) sudden cardiac deaths (SCD) occur in young victims without identifiable abnormalities.
- Trial name
- IQARE-SCD (NCT03387072)
- Testing
- Non interventional study
- Where
- 4 sites in France
- Volunteers
- 394 people
- Sponsor
- Nantes University Hospital
Behavior and Behavior Mechanisms
A Parent-Based Intervention to Reduce Sexual Risk Behavior in Adolescents
The purpose of this study is to test the feasibility and efficacy of a triadic intervention designed to target both healthcare providers and parents in order to prevent adolescent sexual risk behavior in Latino and African…
- Trial name
- NCT01326806
- Testing
- Families Talking Together, Active Control on Hygiene & Nutrition
- Where
- United States
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- New York University
Behavior and Behavior Mechanisms
Couple & Family Contexts
The purpose of this study is to understand the factors that lead to adolescent sexual risk behavior by investigating both the family contexts and romantic relationships that influence adolescent couples' decision-making.
- Trial name
- CFC (NCT01631721)
- Where
- United States
- Volunteers
- 2,960 people, healthy volunteers welcome
- Sponsor
- New York University
Disruptive Mood Dysregulation Disorder, Attention Deficit Hyperactivity Disorder
Symptoms and Mechanisms of Child Psychiatric Disorders
In this study the investigators will examine psychiatric symptoms, central neurocognitive functions, parental stress and attachment styles, and biological factors that can give new knowledge about some of the mechanisms present…
- Conditions
- Disruptive Mood Dysregulation Disorder, Attention Deficit Hyperactivity Disorder, Oppositional Defiant Disorder, Severe Irritability
- Trial name
- NCT05049356
- Where
- 2 sites in Norway
- Volunteers
- 218 people
- Sponsor
- Oslo University Hospital
Pediatric Obesity, Behavior and Behavior Mechanisms
Neuro-cognitive Impact of Juvenile Obesity
Recent studies indicate that obese teenagers exhibit memory disturbances. Adolescence represents a crucial period in the development of the hippocampus and the amygdala, necessary for the implementation of memory and emotional…
- Conditions
- Pediatric Obesity, Behavior and Behavior Mechanisms, Emotions
- Trial name
- OBETEEN (NCT03776513)
- Testing
- an MRI examination
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Depression Mild, Depression Moderate
Neural Mechanisms of Meditation Training in Healthy and Depressed Adolescents: An MRI Connectome Study PART 2
The primary objective will be to study changes in putamen connectivity and depression severity in depressed teens with meditation training.
- Conditions
- Depression Mild, Depression Moderate, Depression, Teen
- Trial name
- NCT05267340
- Testing
- TARA, Psycho-Education
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of California, San Francisco
Spinal Muscular Atrophy
Mechanisms and Treatment of Exercise Intolerance and Persistent Fatigue in Spinal Muscular Atrophy
This study will focus on the pathophysiological underpinnings of reduced exercise capacity and fatigue in ambulatory patients with spinal muscular atrophy (SMA).
- Trial name
- NCT05518773
- Testing
- Observational
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Columbia University
Bariatric Surgery Candidate, Lipid Metabolism Disorders
Lipid Metabolism in Obese Subjects Undergoing Bariatric Surgery
The aim of the study is to evaluate modifications in the metabolism of polyunsaturated fatty acids (PUFA) and biosynthesis of the lipid mediators N-acylethanolamines (NAE), both known to induce and be induced by the nuclear…
- Conditions
- Bariatric Surgery Candidate, Lipid Metabolism Disorders, Obesity
- Trial name
- NCT04984785
- Where
- Italy
- Volunteers
- 68 people
- Sponsor
- University of Cagliari
Obesity, Childhood, Binge Eating
Project REST: Regulation of Eating and Sleep Topography
Overweight/obesity and inadequate sleep are prevalent, and frequently co-occurring, health risks among children, both of which are associated with serious medical and psychosocial health complications including risk for…
- Conditions
- Obesity, Childhood, Binge Eating, Sleep, Self-regulation
- Trial name
- NCT04057716
- Testing
- Sleep restriction, Sleep extension
- Where
- 2 sites in United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Obsessive-Compulsive Disorder (OCD)
Neural Predictors and Neural Changes Associated With Cognitive Behavior Therapy for Obssesive Compulsive Disorder
The goals of the project are 1) to understand what are the neural mechanisms involved in the psychological treatment of obsessive-compulsive disorder (OCD) in children/adolescents and adults, 2) to assess potential differences in…
- Trial name
- NCT04042038
- Testing
- Cognitive-behavior therapy (psychological treatment)
- Where
- 3 sites in Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Institut d'Investigació Biomèdica de Bellvitge