Clinical trials: Benign Neoplasm
Skin Cancer
Multi-Center Study to Evaluate the Performance of DermDx for Primary Care Physicians in the Detection of Skin Cancers
The proposed study is a pivotal, multi-center retrospective reader study designed to determine whether the use of DermDx as a concurrent reading aid improves the performance of primary care physicians (PCPs) in diagnosing skin…
- Trial name
- NCT06463860
- Testing
- DermDx
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- MetaOptima Technology Inc.
Skin Cancer, Skin Cancer Prevention
Developing and Testing the Effectiveness of a Skin Cancer Self-Detection Educational Program
Skin cancer is a significant public health concern, even in an Asian society like Singapore where it ranks among the top 10 cancers.
- Conditions
- Skin Cancer, Skin Cancer Prevention, Benign Skin Growth
- Trial name
- NCT07247123
- Testing
- Skin Cancer Self-Detection Educational Program with gain-framing, Skin Cancer Self-Detection Educational Program with loss-framing, Wait-list Control
- Where
- Singapore
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Adnexal Mass, Adnexal Tumor
Masses in Young Patients - International Ovarian Tumour Analysis (MY-IOTA)
This multicenter observational study aims to validate the IOTA Simple Rules, Benign Descriptors, and ADNEX model in a cohort of patients equal or under the age of 20.
- Conditions
- Adnexal Mass, Adnexal Tumor, Adnexal Cyst, Adnexal Masses in Young Girls and Adolescents
- Trial name
- MY-IOTA (NCT06693596)
- Testing
- Group 2: Conservative management (follow-up), Group 1: Surgical management
- Where
- Belgium
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Benign Skin Tumor, Basal Cell Carcinoma
Study to Examine Lesions of the Skin Using Confocal Laser Microscopy
Using ex-vivo confocal laser scanning microscopy, a reliable statement can be made about the extent, histological structure and possible significance of a skin change without having to send tissue samples for demanding and…
- Conditions
- Benign Skin Tumor, Basal Cell Carcinoma, Melanoma, Squamous Cell Cancer
- Trial name
- NCT06598137
- Testing
- Ex vivo confocal laser microscopy
- Where
- Germany
- Volunteers
- 645 people, healthy volunteers welcome
- Sponsor
- LMU Klinikum
Melanoma
Moletest Clinical Study in Scotland
To evaluate an iPad based photoimage analysis system (Moletest) for improving discrimination of benign from malignant suspicious skin lesions or moles.
- Trial name
- NCT02196246
- Where
- United Kingdom
- Volunteers
- 1,120 people, healthy volunteers welcome
- Sponsor
- Moletest Scotland Ltd
Zhejiang University
Split or Whole Liver Transplantation? A Multicenter Retrospective Cohort Study of Patients With Benign and Malignant Liver Disease
The primary objective of this study was to assess the safety and feasibility of split liver transplantation(SLT) for adult hepatocellular carcinoma (HCC) patients, while comparing the prognostic disparities between adult SLT and…
- Trial name
- NCT06359496
- Testing
- No intervention factor
- Where
- China
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Zhejiang University
Cancer
Evaluation the Feasibility of the FOSTI Device
Feasibility of accurate differentiation between malignant and benign tissue using the FOSTI device on surgically removed tissue
- Trial name
- NCT00791609
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Optivasive Ltd.
Prostate Cancer, Bladder Cancer
Duke Urology Database and Specimen Bank
The proposed project is aimed to build a Duke University-specific longitudinal urologic surgery database. It will be used as the main resource to support future research within Urology and Duke University.
- Conditions
- Prostate Cancer, Bladder Cancer, Erectile Dysfunction, Incontinence
- Trial name
- NCT00978991
- Where
- United States
- Volunteers
- 87,820 people, healthy volunteers welcome
- Sponsor
- Duke University
Lung Cancer (Diagnosis), Pulmonary Nodule Persistent
Multi-omics Detection Techniques for Differentiating Benign and Malignant Pulmonary Nodules
Research objective: To explore the clinical application effect of multi-omics detection based on flow cytometry analysis, single-cell data and images combined with clinical features in differentiating the benign and malignant…
- Trial name
- NCT07047573
- Testing
- PBMCS were isolated from the peripheral blood of hospitalized patients with pulmonary nodules and incubated with nanoparticles loaded with tumor antigens for a specific period of time to detect cancer
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Zhao Jun
Odontogenic Tumors, Odontoma
Computer Guided Buccal Cortical Plate Separation for Removal of Calcified Benign Odontogenic Tumors Affecting Mandibular Angle Region
Computer guided buccal cortical plate separation was performed for ten patients using patient specific osteotomy locating guides and pre-bent plates.
- Trial name
- NCT05329974
- Testing
- Computer guided buccal cortical plate separation
- Where
- 2 sites in Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Breast Cancer, Benign Breast Disease
Evaluating Scaleup of an Adapted Breast Cancer Early Diagnosis Program in Rwanda
Breast cancer incidence is increasing in low- and middle-income countries (LMICs) and breast cancer mortality is high in these regions largely due to late stage diagnoses.
- Conditions
- Breast Cancer, Benign Breast Disease, Cervix Cancer
- Trial name
- NCT05364138
- Where
- Rwanda
- Volunteers
- 2,357 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Neurofibromatosis 2, Vestibular Schwannoma
Lapatinib Study for Children and Adults With Neurofibromatosis Type 2 (NF2) and NF2-Related Tumors
The purpose of this study is to determine if Lapatinib has any effect on tumors found in patients with Neurofibromatosis Type 2 (NF2). NF2 is a condition that mainly affects the skin and nervous system.
- Trial name
- NCT00973739
- Testing
- Lapatinib
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Thyroid Nodule
Application of Ultrasonic Gray-scale Ratio in Differentiating Benign From Malignant Thyroid Nodules.
According to the grades of echogenicity to evulated thyroid nodules is a subjective process and is thus influenced by the observer's judgement.
- Trial name
- NCT03700762
- Testing
- ultrasound gray-scale ratio
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- First People's Hospital of Hangzhou
Breast Cancer
CRRS-4 Pivotal Somo•v™ ABUS ROC Reader Observer Study
To determine the impact on Interpreting Physician performance in detecting breast cancer, as defined by the area under the Receiver Operating Characteristic Curve (ROC), when Automated Breast Ultrasound (ABUS) and screening…
- Trial name
- NCT01424956
- Testing
- Automated Breast Ultrasound (ABUS)
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- U-Systems, Inc.
Thyroid Nodule
Percutaneous Ethanol Injection for Benign Cystic Thyroid Nodules
Use of ethanol injection in treatment of cystic thyroid nodule
- Trial name
- NCT03257930
- Testing
- ethanol injection
- Where
- Egypt
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- hassan harby mohamed
Nevus
In Vivo Confocal Scanning Laser Microscopy of Benign Nevi
In vivo confocal laser scanning microscopy (CLSM) offers the possibility to non-invasively investigate skin lesions at nearly histologic resolution.
- Trial name
- CSLM-nevi (NCT00487864)
- Where
- Austria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Nevi
Study to Test Genetic Alterations Among Different Dermoscopic Types of Melanocytic Nevi.
This project is a multicenter study in which we will investigate a dual concept of nevogenesis. Study location is the Department of Dermatology at the Medical University of Graz in collaboration with centers in Austria (Vienna)…
- Trial name
- NCT00422448
- Testing
- To test the frequency of BRAF and NRAS mutations among nevi
- Where
- Austria
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Endoscopic Breast Surgery, Benign Breast Tumors
Endoscopic Extirpation of Benign Breast Tumors Using a Lateral Chest Wall Incision
1. A new surgical method for breast surgery has been introduced, which involves the removal of benign breast tumors through endoscopic surgery, thereby avoiding noticeable scarring on the breast. 2.
- Trial name
- NCT06472700
- Testing
- No intervention
- Where
- China
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Cancer Risk, Cancer Predisposition Syndrome
InAdvance: Surveillance, Prevention, and Interception in a Population at Risk for Cancer
This research study is creating a way to collect and store specimens and information from participants who may be at an increased risk of developing cancer, or has been diagnosed with an early phase of a cancer or a family member…
- Conditions
- Cancer Risk, Cancer Predisposition Syndrome, Hereditary Cancer Prediction, Childhood Cancer Survivors
- Trial name
- NCT05463796
- Testing
- Samples
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute