Clinical trials: Biochemical Marker
Heart Failure, Congenital Heart Defects
Right Ventricular Failure in Congenital Heart Defects
Usually, "heart failure" refers to myocardial insufficiency of the left ventricle. However, in patients with congenital heart defects, often predominantly the right ventricle is affected.
- Trial name
- NCT00266201
- Where
- 9 sites in Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Competence Network for Congenital Heart Defects
Sjogren-Larsson Syndrome (SLS)
Sjogren-Larsson Syndrome: Natural History, Clinical Variation and Evaluation of Biochemical Markers
Sjogren-Larsson syndrome (SLS) is a rare genetic disease in which patients typically exhibit ichthyosis (dry, scaly skin), intellectual disability, spasticity, seizures and a distinctive maculopathy.
- Trial name
- SLS (NCT01971957)
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Nebraska
Acromegaly
Surgical Versus Medical Treatment of Acromegaly
Evaluate biochemical differences in acromegalic patients treated with surgery versus somatostatin analogues (SMS) (after surgery or alone). Hypothesis: Treatment modality exhibit different biochemical responses in acromegaly.
- Trial name
- NCT01000090
- Where
- Denmark
- Volunteers
- 63 people
- Sponsor
- University of Aarhus
Abdominal Pain, Functional Abdominal Pain
Epidemiological Analysis for Hereditary Angioedema Disease
An international, multicenter, epidemiological, observational study investigating the prevalence of Hereditary Angioedema (HAE) disease among participants with recurrent episodes of abdominal pain of no obvious etiology.
- Trial name
- EHA (NCT03558009)
- Where
- 35 sites in Germany, Italy and 4 more
- Volunteers
- 2,318 people
- Sponsor
- CENTOGENE GmbH Rostock
Child Development, Cognitive Development
Efficacy of Micronutrient Fortified Yoghurt in School Children for Health Benefits
To evaluate the efficacy of consumption of yoghurt fortified with 30% recommended dietary allowance (RDA) of essential micronutrients (iron, zinc, vitamin A and iodine) for a period of one year in comparison to same yoghurt…
- Conditions
- Child Development, Cognitive Development, Morbidity, Physical Growth
- Trial name
- NCT00980733
- Testing
- Fortified Yoghurt, Yoghurt
- Where
- Bangladesh
- Volunteers
- 1,325 people
- Sponsor
- Annamalai University
Cardiotoxicity, Aluminum Phosphid Poisoning
Cardiotoxicity of Aluminum Phosphide Poisoning; Tropinin and CKmb as Early Biomarkers
Aluminum phosphide (AlP) or rice tablet is a cheap pesticide. When it comes in contact with acid (gastric acid) or moisture, it releases phosphine (PH3) gas.
- Trial name
- NCT04191265
- Testing
- serum tropinin, serum CKmb
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Beta-Thalassemia
Iron Status in BTM With Blood Transfusion
To assess the possible role of iron overload as a cause of liver dysfunction in thalassemic childrens receiving multiple blood transfusion and its correlation with serum aminotransferases.
- Trial name
- NCT04947540
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Behcet Disease and Vascular Involvement
Clinical, Biochemical and Epigenetic Profile of Pediatric Behçet Disease
Behçet disease (BD) is a chronic multisystem inflammatory disorder with a relapsing-remitting course. Pediatric-onset BD is rare and characterized by marked clinical heterogeneity, frequent incomplete presentation at disease…
- Trial name
- PED-BD (NCT07375940)
- Testing
- Biomarker analysis of blood samples
- Where
- 2 sites in Italy, United Kingdom
- Volunteers
- 90 people
- Sponsor
- Meyer Children's Hospital IRCCS
Paget's Disease of Bone
18F-Fluoride Positron Emission Tomography (PET) in Paget's Disease of Bone
18 F-fluoride Positron emission tomography (PET) is able to demonstrate and quantify the metabolic activity locally in the skeleton (1).
- Trial name
- NCT00306046
- Testing
- Bisphosphonate treatment
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Université Catholique de Louvain
Soccer, Fatigue
Comparison Between Photobiomodulation Therapy (PBMT) and a Cold-Water Immersion (CWI) in Recovery Soccer Player: Analysis of Biochemical Markers of Recovery and Muscular Oxidative Stress.
Competitive soccer engages many of the body's systems to a major extent. The musculoskeletal, nervous, immune and metabolic systems are stressed to a point where recovery strategies post-exercise become influential in preparing…
- Conditions
- Soccer, Fatigue, Oxidative Stress, Recovery
- Trial name
- NCT03593733
- Testing
- Photobiomodulation Therapy, Cold Water Immersion
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- LUCIANA MARIA MALOSA SAMPAIO
Congenital Heart Disease, Cardiopulmonary Bypass
Acetaminophen for Oxidative Stress After Cardiopulmonary Bypass
The current proposal tests the central hypothesis that acetaminophen will attenuate the oxidative stress response associated with cardiopulmonary bypass (CPB)-induced hemolysis in children undergoing cardiac surgery.
- Trial name
- NCT01228305
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Vanderbilt University Medical Center
Obese Adolescents, Overweight
Effect of Acute Exercise on Biochemical Parameters in Normal-Weight and Overweight/Obese Adolescent.
The goal of this interventional clinical trial is to compare the acute physiological and biochemical responses to maximal physical exercise (Spartacus test).
- Trial name
- NCT07103889
- Testing
- Spartacus Test
- Where
- Tunisia
- Volunteers
- 35 people
- Sponsor
- High Institute of Sports and Physical Education of Kef
Sports Nutrition, Biochemical Markers
Effect of a Short-term Multi-strain Probiotic Supplementation in Endurance Athletes
The aim of this project is to evaluate and identify the effect of a short-term 2-week multi-strain probiotic (MPRO) supplementation on the exercise-associated gastrointestinal (GI) symptoms and perturbations in high level female…
- Conditions
- Sports Nutrition, Biochemical Markers, Exercise Performance, Aerobic Capacity
- Trial name
- NCT07252778
- Testing
- MPRO supplementation
- Where
- Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Krzysztof Durkalec-Michalski
Leukemia, HSCT
Comparison of Intralipid With SMOF Lipid Following HSCT
The goal of this clinical trial is to have a successful engraftment in after bone transplantation. Acute leukemia patient of both sexes aged 2 to 18 years, who are transplant candidates, participate in this study.
- Trial name
- NCT06625372
- Testing
- SMOF lipid, INTRALIPIDS
- Where
- Iran
- Volunteers
- 50 people
- Sponsor
- Shahid Beheshti University
Blood Disease
Cystatin c and Beta 2 Microglobulin in Thalassemic Children.
Beta thalassemia has many complications on many systems as the renal system.So early detection of renal impairment is required in those children to decrease complications of this nephropathy.
- Trial name
- NCT03881917
- Testing
- Cystatin c and beta 2 microglobulin kits
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cystic Fibrosis
Choline Nutrition in Children With Cystic Fibrosis (CF)
Cystic Fibrosis (CF) is a complex disease with a wide range of clinical problems. Despite enzyme replacement therapy, children with cystic fibrosis (CF) may still have problems absorbing some nutrients.
- Trial name
- NCT00686361
- Testing
- Choline supplementation
- Where
- Canada
- Volunteers
- 34 people
- Sponsor
- University of British Columbia
Neurological Complication of Procedure (Disorder)
Novel BIochemical Markers for Predicting Type 2 NEurological Complications of Surgical Coronary Revascularization (BINER)
In this single center prospective cohort study a total of 100 patients scheduled for elective off-pump CABG will be recruited. They will be allocated to one study and one control group according to the presence or absence of…
- Trial name
- BINER (NCT03493256)
- Testing
- exposure to type 2 neurological complications
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Collegium Medicum w Bydgoszczy
Pancreatectomy; Hyperglycemia, Diabete Mellitus
Glucose Metabolism After Partial Pancreatectomy
This is a single center observational study to assess alteration of glucose metabolism after pancreatectomy.
- Trial name
- NCT04409171
- Testing
- oral glucose tolerance test
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Supplementation, Sports
Effects of β-alanine and Sodium Bicarbonate Supplementation on Physical Capacity and Biochemical Markers Concentrations
This randomized, double-blind, placebo-controlled, parallel-group study aims to evaluate the potential synergistic effect of beta-alanine (BA) and sodium bicarbonate (SB) supplementation, compared to their separate administration…
- Conditions
- Supplementation, Sports, Female Athletes
- Trial name
- NCT07092930
- Testing
- BA and SB supplementation, BA and PL2 supplementation, PL1 and SB supplementation
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Preeclampsia, Intrauterine Growth Restriction
First Trimester Placental Assessment in the Screening of Preeclampsia and Intrauterine Growth Restriction
Preeclampsia (PE) and intrauterine growth restriction (IUGR) are clinical manifestations of placental insufficiency. These complications affect 5-15% of pregnancies, and are responsible for up to 20% of preterm births.
- Trial name
- NCT02879942
- Testing
- Ultrasound study of the placenta, Measurement of angiogenic and anti-angiogenic factors (sFlt-1 and PlGF) in the first trimestre blood test
- Where
- Spain
- Volunteers
- 1,390 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau