Clinical trials: Biologic Markers
Osteoporosis, Postmenopausal, Osteoporosis Fracture
New Biomarkers and Therapeutic Targets in Osteoporosis Via Omics Technologies
This study aims to discover novel biomarkers and therapeutic targets for osteoporosis through the use of advanced omics technologies, including proteomics and metabolomics.
- Conditions
- Osteoporosis, Postmenopausal, Osteoporosis Fracture, Osteoporosis, Severe
- Trial name
- NCT06525688
- Testing
- Bone, Serum and Plasma sample
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- National and Kapodistrian University of Athens
LRTI, UTI
Observational, Prospective Clinical Study to Evaluate Biomarkers as Indicators of Acute Bacterial or Viral Infections
This is an observational prospective study of an in-vitro diagnostic (IVD) assay planned to enroll 632 subjects. The study will be conducted in two stages: Stage A is aimed at identifying individual biomarkers and constructing a…
- Conditions
- LRTI, UTI, Gastroenteritis, Systemic Infections/Bacteremia/Meningitis
- Trial name
- CURIOSITY (NCT01917461)
- Where
- 2 sites in Israel
- Volunteers
- 1,001 people, healthy volunteers welcome
- Sponsor
- MeMed Diagnostics Ltd.
Pediatric Obesity, Periodontal Disease
Dental and Periodontal Health in Obese Adolescents: Clinical, Biochemical, and Microbiological Evaluation
This study aims to investigate whether obesity affects oral and gum health in children and adolescents. A total of 75 children aged 8 to 13 years participated, including both obese and non-obese individuals.
- Conditions
- Pediatric Obesity, Periodontal Disease, Inflammation Biomarkers, Dental Plaque
- Trial name
- PERIOBESITY (NCT07086027)
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Marmara University
Osteoporosis
Thai Traditional Massage Increases Biochemical Marker of Bone Formation in Postmenopausal Women
To investigate the skeletal effect of Thai traditional massage by examining the changes in biochemical markers of bone turnover.
- Trial name
- NCT01627028
- Testing
- Thai traditional massage
- Where
- Thailand
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Muscular Dystrophies, Becker Muscular Dystrophy
Evaluation of Muscle miRNA as Biomarkers in Dystrophinopathies
Duchenne muscular dystrophy (DMD) , caused by mutations in the DMD gene, is the most common and most severe progressive dystrophy of the child.
- Conditions
- Muscular Dystrophies, Becker Muscular Dystrophy, Duchenne Muscular Dystrophy
- Trial name
- biodystromirs (NCT02109692)
- Testing
- blood sample
- Where
- France
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Breast Cancer
Nutrition-Related Biomarkers in Predicting Breast Cancer Risk in Women
RATIONALE: Studying samples of blood from patients with cancer in the laboratory may help doctors learn more about nutrition-related changes that identify biomarkers related to cancer.
- Trial name
- NCT00900367
- Testing
- high performance liquid chromatography, laboratory biomarker analysis, spectroscopy
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Non-ischemic Cardiomyopathy
Non-ischemic Cardiomyopathy Registry, Biobank and Imaging Data Repository
The main goal of CaNICM is to create a central database that includes a biobank and an imaging data repository for patients with non-ischemic cardiomyopathy (NICM), as well as for at-risk family members.
- Trial name
- CaNICM (NCT07110818)
- Where
- Canada
- Volunteers
- 2,000 people
- Sponsor
- Montreal Heart Institute
Lymphoma
Biomarkers in Tissue Samples From Patients With Hodgkin Lymphoma Enrolled on ECOG-2496 Clinical Trial
RATIONALE: Studying samples of tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
- Trial name
- NCT01505712
- Testing
- gene expression analysis, laboratory biomarker analysis
- Volunteers
- 393 people
- Sponsor
- ECOG-ACRIN Cancer Research Group
Joint Infection, Infection of Hip Joint (Disorder)
Alpha-Defensin and Synovial Proteins to Improve Detection of Pediatric Septic Arthritis
Differentiating between septic arthritis and other causes of joint inflammation in pediatric patients is challenging and of the utmost importance because septic arthritis requires surgical debridement as part of the treatment…
- Conditions
- Joint Infection, Infection of Hip Joint (Disorder), Infection of Shoulder Joint, Septic Arthritis
- Trial name
- NCT03704766
- Testing
- Synovial Alpha-defensin assay, Synovial Neutrophil elastase assay, Synovial lactate assay
- Where
- 3 sites in United States
- Volunteers
- 442 people
- Sponsor
- Hospital for Special Surgery, New York
Type 1 Diabetes Mellitus
Biomarkers of Type 1 Diabetes in Children and Their Healthy Siblings
This prospective observational cohort study evaluated genetic, immunologic, and environmental factors associated with type 1 diabetes in children.
- Trial name
- NCT07627230
- Where
- Russia
- Volunteers
- 1,034 people, healthy volunteers welcome
- Sponsor
- Privolzhsky Research Medical University
Diabetes Type II
Novel Biomarker for Development of T2D
The investigators wants to determine if 11β-HSD1 activity will be positively associated, and 5α-reductase activity negatively associated, with (a) degree of insulin resistance defined by the homeostatic model assessment of…
- Trial name
- NCT02326129
- Where
- 3 sites in United States
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Duke University
Leukemia, Cancer
WT1 for the Detection of Minimal Residual Disease
The purpose of this study is to determine if WT1 is an adequate measurement of minimal residual disease in leukemic patients.
- Trial name
- NCT00179829
- Testing
- WT 1 Testing
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Colo-rectal Cancer
EMVI as a Determinant of Metastasis in Colorectal Cancer
Bowel cancer is the fourth most commonly occurring cancer and the second highest cause of cancer deaths in the UK. Despite advances in treatment, over 40% of patients will die within 5 years.
- Trial name
- EVIDENCE (NCT06646341)
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Imperial College London
Breast Cancer
Study of Biomarkers in Tissue Samples From Patients With Breast Cancer
RATIONALE: Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
- Trial name
- NCT01004796
- Testing
- cytogenetic analysis, microarray analysis, mutation analysis
- Sponsor
- University of Wisconsin, Madison
Emotions, Dementia
Dementia Associated Apathy.
We want to determine if patients with dementia show any kind of emotion while they look at a defined selection of photos. These are photos taken from a international image-platform and mixed with photos (biographic) that show…
- Conditions
- Emotions, Dementia, Apathy
- Trial name
- NCT03293537
- Testing
- Skin conductance and Heart rate measurement
- Where
- Switzerland
- Volunteers
- 133 people
- Sponsor
- Zurich University of Applied Sciences
Immunisation Anxiety Related Reaction, Pain, Acute
Substance P as a Biomarker to Evaluate the Reduction of Multiple Immunization Pain
Immunization is one of the most significant preventive health measures in reducing morbidity and mortality caused by infectious diseases.
- Trial name
- NCT04103801
- Testing
- Sucrose
- Where
- Jordan
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Neoplasms Pancreatic
PRIMUS 001: A Study Looking at Two Different Chemotherapy Regimens in Patients With Metastatic Pancreatic Cancer
This study is comparing two combinations of chemotherapy treatments in patients with metastatic pancreatic cancer. Half the participants will receive FOLFOX-A and the other half will receive AG.
- Trial name
- NCT04151277
- Testing
- FOLFOX-A, Gemcitabe and Abraxane, G-CSF
- Where
- 30 sites in United Kingdom
- Volunteers
- 500 people
- Sponsor
- Judith Dixon-Hughes
Wilson's Disease
Cohort Research on Wilson's Disease
Wilson's disease (WD) is an inherited disorder that causes abnormal copper accumulation in the brain and/or liver. Some people develop neurological or psychiatric symptoms whereas other develop liver disease.
- Trial name
- CROWD (NCT04212195)
- Testing
- Next generation sequencing, Imaging and fluid biomarkers
- Where
- 11 sites in United Kingdom
- Volunteers
- 500 people
- Sponsor
- University College, London
New Persistent Daily Headache
NDPH Biomarker Study in Children and Adolescents
This study will recruit pediatric patients with NDPH (New Daily Persistent Headache), characterize their headache in a standard manner, and treat the NDPH with standard medications used for treatment of headaches in this…
- Trial name
- NCT06018025
- Testing
- CGRP antibody
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Duke University
Inflammatory Myopathy, Duchenne Muscular Dystrophy
Quantitative Muscle Ultrasound as a Marker of Progression in Children With Muscular Diseases
The aim of our study is to Assess skeletal muscle structural status in children with inflammatory myositis and Duchenne muscular dystrophy using musculoskeletal ultrasound and to perform a longitudinal follow up of these changes…
- Trial name
- NCT03786913
- Testing
- Quantitative muscle ultrasound measurements
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Benha University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.