Clinical trials: Biological Samples, open to volunteers
Sample Collection
Apheresis and Specimen Collection Procedures to Obtain Plasma, Peripheral Blood Mononuclear Cells (PBMCs) and Other Specimens for Research Studies
This study collects specimens from volunteers for use in studies by NIAID's Vaccine Research Center. A number of different types of specimens or samples can be collected, including blood, urine, body fluids or secretions, skin…
- Trial name
- NCT00067054
- Where
- 3 sites in United States, Puerto Rico
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Normal and Diseased Tissue and Body Fluids Samples
Protocol for Collecting, Banking and Distributing Human Tissue Samples: St. Jude Children's Research Hospital Tissue Resources Core Facility
The aims of this protocol are: to collect and store diseased and normal tissue and body fluid samples from new and returning patients at St.
- Trial name
- NCT01354002
- Where
- 14 sites in United States
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- St. Jude Children's Research Hospital
Multiple Osteochondromas
Registry of Multiple Osteochondromas
REM is a retrospective and prospective registry, finalized for care and research purposes. It is articulated in main sections - strongly related and mutually dependent on each other - corresponding to different data domains…
- Trial name
- REM (NCT04133285)
- Where
- Italy
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Luca Sangiorgi
Ehlers-Danlos Syndrome
Registry of Ehlers-Danlos Syndrome
RED is a retrospective and prospective registry, finalized for care and research purposes. It is articulated in main sections - strongly related and mutually dependent on each other - corresponding to different data domains…
- Trial name
- RED (NCT04133272)
- Where
- Italy
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Luca Sangiorgi
Miscarriage, Parodontitis
PERIodontal Disease, Microbiota and Miscarriage
Cross-sectional non-interventional observational pilot study recruiting women whom had repeated miscarriages (= at least 3 miscarriages).The information will be collected during a routine maintenance, complete oral clinical and…
- Trial name
- PERI2M (NCT06576622)
- Testing
- biological sampling
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Toulouse
Healthy Volunteers
Collection and Analysis of Blood, Bone Marrow, and Buccal Mucosa Samples From Healthy Volunteers
The Hematology Branch of the National Heart, Lung, and Blood Institute is doing a variety of laboratory research experiments that require blood and tissue samples from healthy volunteers.
- Trial name
- NCT00442195
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
HIV, Viral Load
Use of Unmanned Air Vehicles (Medical Drones) to Overcome Geographical Barriers to Delivery of Anti-Retroviral Therapy and Biological Samples
The goal of this clinical trial is to learn if the intervention of delivery of antiretroviral drugs by medical drones can improve virological suppression in a fisherfolk community population living with HIV in the islands of…
- Trial name
- MRC-DRONES (NCT06678022)
- Testing
- No Drone delivery, Fixed Wing drones
- Where
- 2 sites in Uganda
- Volunteers
- 1,086 people
- Sponsor
- Makerere University
Bone Marrow Failure Syndrome
French National Registry of Bone Marrow Failures
This is a unique clinical and biological database that collects standardized clinical information during the management of all patients with bone marrow failure syndromes (BMF) in France (multicenter registry), from diagnosis and…
- Trial name
- RIME (NCT04781790)
- Testing
- Bone Marrow Failure
- Where
- France
- Volunteers
- 5,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Osteogenesis Imperfecta
Registry of Osteogenesis Imperfecta
ROI is a retrospective and prospective registry, finalized for care and research purposes. It is articulated in main sections - strongly related and mutually dependent on each other - corresponding to different data domains…
- Trial name
- ROI (NCT04115774)
- Testing
- bisphosphonates
- Where
- Italy
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Luca Sangiorgi
Genetic Diseases
Rady Children's Institute Genomic Biorepository
Rady Children's Institute for Genomic Medicine (RCI) will collect biological samples (such as blood), derived genomic sequences (from DNA and RNA), and clinical features in a Biorepository as a standardized resource for future…
- Trial name
- NCT02917460
- Testing
- Genomic sequencing and molecular diagnostic results, if any
- Where
- United States
- Volunteers
- 102,000 people, healthy volunteers welcome
- Sponsor
- Rady Pediatric Genomics & Systems Medicine Institute
Autoimmune Bullous Dermatosis, Dysimmune Dermatological Diseases
Clinico-biological Collection of Autoimmune, Dysimmune or Auto-inflammatory Dermatological Diseases
The aim of this project is to start a biological and clinical collection of patients presenting autoimmune, dysimmune or auto-inflammatory dermatological diseases.
- Conditions
- Autoimmune Bullous Dermatosis, Dysimmune Dermatological Diseases, Auto-inflammatory Dermatological Diseases, Skin Diseases
- Trial name
- TekAPo (NCT06387654)
- Testing
- Blood sampling, Remainders of samples taken as part of the treatment
- Where
- France
- Volunteers
- 800 people
- Sponsor
- University Hospital, Toulouse
Healthy, Cancer
Archival of Human Biological Samples in CU-Med Biobank
CU-Med Biobank collaborates with different researchers for collecting and distributing human biospecimens and clinical data for assisting scientific research.
- Conditions
- Healthy, Cancer, Heart Diseases, Neurological Diseases or Conditions
- Trial name
- NCT04706481
- Testing
- Specimen Collection
- Where
- Hong Kong
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Genetic Diseases, Genetic Syndrome
Rapid Whole Genome Sequencing Study
Rapid Whole Genome Sequencing (rWGS) has proven to provide much faster diagnoses than traditional clinical testing, including clinical Whole Exome Sequencing (WES) and standard Whole Genome Sequencing (WGS).
- Trial name
- rWGS (NCT03385876)
- Testing
- Genomic sequencing and molecular diagnostic results, if any
- Where
- United States
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Rady Pediatric Genomics & Systems Medicine Institute
Periodontitis, Trisomy 21
Periodontitis and Inflammation in Children With Down Syndrome/Trisomy 21: Study on Biological Samples
Since 2018, the Chicago Classification of Periodontal Diseases and Conditions, has listed Down syndrome (DS)/trisomy 21 (T21) as a systemic disease with periodontal implications.
- Trial name
- NT21 (NCT05970965)
- Testing
- Biological sampling
- Where
- France
- Volunteers
- 18 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Nervous System Diseases
Collection of Biological Samples From Patients With Rare Neurological Diseases
The aim of this project is to improve biological collections of patients presenting rare neurological disorders with known or suspected autoimmune origin.
- Trial name
- EXPLAINEUR (NCT04698421)
- Testing
- Blood collection on admission and longitudinally
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Toulouse
Oncologic Disease, Hematologic Diseases
Molecular Characterizazion and Biological Samples Centralisation of Patients Affected by Oncoematolofic Pathology
Currently, the molecular characterization of onco-hematological, onco-immunological and hematological diseases, at onset or in relapse, of patients with suspected diagnosis afferent to the CROP centers, is done through…
- Trial name
- NCT06304194
- Testing
- Analysis of biological samples
- Where
- 3 sites in Italy
- Volunteers
- 340 people
- Sponsor
- Meyer Children's Hospital IRCCS
Echinococcosis
Collection of Biological Samples From Patients With Echinococcosis and Implementation of a Home-made PCR Method
Echinococcosis is a zoonotic disease caused by Echinococcus species. Diagnosis currently relies on imaging, serology and microscopy, but microscopy is time-consuming, has limited sensitivity and cannot distinguish between…
- Trial name
- Echino_home (NCT07715435)
- Testing
- Collection of biological samples from echinococcosis patients for the development of a home-based PCR protocol for diagnostic use.
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria
Condition
Intermountain INSPIRE Registry
To collect biological samples, clinical information and laboratory data from patients diagnosed with any healthcare-related conditions who are seen at facilities affiliated with Intermountain Healthcare, including patients and…
- Trial name
- NCT02450006
- Where
- United States
- Volunteers
- 50,000 people, healthy volunteers welcome
- Sponsor
- Intermountain Health Care, Inc.
Ollier Disease, Maffucci Syndrome
Registry of Ollier Disease and Maffucci Syndrome
REM is a retrospective and prospective registry, finalized to care and research. It is articulated in main sections - strongly related and mutually dependent on each other - corresponding to different data domains: personal…
- Trial name
- ROM (NCT04134572)
- Where
- Italy
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Luca Sangiorgi
Pediatric Brain Tumors, Genomics
GenoDrugP 2025: Study on Three-dimensional Models Derived From Brain Tumors in Pediatric Patients
Central nervous system tumours are the most common solid tumours and the leading cause of cancer mortality in children, with high biological and prognostic heterogeneity.
- Conditions
- Pediatric Brain Tumors, Genomics, Epigenetic
- Trial name
- NCT07417072
- Testing
- Genomic DNA analysis of biological samples
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Meyer Children's Hospital IRCCS