Clinical trials: Bipolar and Related Disorders
Schizophrenia, Bipolar Disorder
Olanzapine Treated Adolescents With Schizophrenia or Bipolar I Disorder
The purpose of this study is to characterize olanzapine pharmacokinetics: the inter- and intra- subject variabilities of olanzapine pharmacokinetics; and the potential influence of patient factors such as age, weight, gender…
- Trial name
- NCT00113594
- Testing
- Olanzapine
- Where
- 17 sites in United States, Puerto Rico and 1 more
- Volunteers
- 100 people
- Sponsor
- Eli Lilly and Company
Bipolar Disorder, Mood Disorders
Delivering Telemetry-Triggered Educational Content Using MyChart in Mood Disorders
Mood disorders - principally major depressive disorder and bipolar disorder - are a significant public health issue affecting one in four people during their lives in total, over 8 million Canadians are affected by mood…
- Trial name
- NCT03575728
- Testing
- MyChart-MHT
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- Sunnybrook Health Sciences Centre
Bipolar Disorder, Major Depressive Disorder
Reducing Suicide Risk in Adolescents and Young Adults Via a Psychobehavioral Intervention to Regularize Daily Rhythms
The purpose of this study is to advance a non-pharmacologic suicide preventive intervention with wide dissemination potential as an innovative high-yield solution to reduce suicide rates.
- Conditions
- Bipolar Disorder, Major Depressive Disorder, Mood Disorders, Suicide
- Trial name
- NCT05317481
- Testing
- BE-SMART-DR, psychoeducational control comparator condition (CC)
- Where
- 2 sites in United States
- Volunteers
- 65 people
- Sponsor
- Yale University
Bipolar Disorder, Attention Deficit Hyperactivity Disorder
Aripiprazole in Children and Adolescents With Bipolar Disorder and Attention Deficit Hyperactivity Disorder (ADHD)
There is a scarcity of clinical trials assessing the effects of medications in children with bipolar disorder. This study aims to assess the efficacy of Aripiprazole (a novel anti-psychotic drug) for the treatment of children and…
- Trial name
- NCT00116259
- Testing
- Aripiprazole
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Federal University of Rio Grande do Sul
Depression, Bipolar
Functional and Neurochemical Brain Changes Bipolar Depression
The purpose of the research is to study brain structure, function and chemistry of patients with bipolar disorder who are receiving quetiapine or lithium, in order to better understand who benefits from treatment and why they…
- Trial name
- NCT00608296
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Cincinnati
Epilepsy, Bipolar Disorder
Lamotrigine Pregnancy Registry (LAM05)
Antiepileptic drugs (AEDs) are not indicated for use in pregnancy. However, women with epilepsy, and other approved indications including bipolar disorder, may require or be unintentionally exposed to AEDs during pregnancy.
- Trial name
- NCT01064297
- Testing
- Lamotrigine monotherapy, Lamotrigine polytherapy including valproate, Lamotrigine polytherapy without valproate
- Volunteers
- 3,416 people
- Sponsor
- GlaxoSmithKline
Bipolar Disorder, Depression
Pediatric Bipolar Registry
The goal of the Pediatric Bipolar Registry (PBR) is to provide a comprehensive assessment regarding the diagnosis and treatment of pediatric bipolar disorder to children and adolescents with any current mood state and/or…
- Conditions
- Bipolar Disorder, Depression, Mania, Psychosis
- Trial name
- PBR (NCT02360267)
- Where
- United States
- Volunteers
- 334 people
- Sponsor
- The University of Texas Health Science Center, Houston
Bipolar Disorder
An Epidemiological Registry Study to Evaluate Clinical Practice Treatment in Patients With Bipolar Disorder
The aim of this study is to describe the treatment pattern and patient characteristics in real life setting in patients with Bipolar disorder treated with Seroquel XR and/or Seroquel IR in Sweden.
- Trial name
- REED (NCT01455961)
- Volunteers
- 16,000 people
- Sponsor
- AstraZeneca
Bipolar Disorder, Mania
Risperidone Versus Olanzapine for Mania in Preschool Children 4 to 6 Years of Age With Bipolar Disorder
The objectives of this study are to study the safety, effectiveness, tolerability and dosing regimen of risperidone, and olanzapine, in the treatment of mania in Bipolar Disorder I and Bipolar II Disorder in preschool children…
- Trial name
- NCT00181935
- Testing
- risperidone (Risperdal), olanzapine (Zyprexa)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Massachusetts General Hospital
Bipolar Disorder
Interpersonal and Social Rhythm Therapy for Adolescents With Bipolar Disorder
This study will evaluate the effectiveness of interpersonal and social rhythm therapy in treating adolescents with a bipolar spectrum disorder
- Trial name
- NCT00576355
- Testing
- Interpersonal and Social Rhythm Therapy for Adolescents (IPSRT-A), Treatment As Usual (TAU)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Washington
Schizophrenia, Bipolar Disorder
Prevalence of Diabetes Mellitus Among Patients Treated With Atypical and Conventional Antipsychotics
This pilot study hypothesizes that diagnosed and undiagnosed prevalence of diabetes mellitus may differ across antipsychotioc medications in a community mental health center.
- Conditions
- Schizophrenia, Bipolar Disorder, Diabetes Mellitus
- Trial name
- NCT00224276
- Volunteers
- 100 people
- Sponsor
- Yale University
Bipolar Disorder
The Evaluation and Follow-up of Patients With Bipolar Disorder
The purpose of this research protocol is to screen and enroll individuals who have bipolar disorder and to track each person's course of illness in order to study the long-term course of illness and to elucidate possible clinical…
- Trial name
- NCT00001652
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- National Institute of Mental Health (NIMH)
Major Depressive Disorder, Bipolar Disorder, Mixed
Chinese Longitudinal and Systematic Study of Bioplar Disorder
Affective disorders (mainly including major depressive disorder and bipolar disorder) are common, chronic and highly disabling mental disorders, which lack of objective biological markers.
- Conditions
- Major Depressive Disorder, Bipolar Disorder, Mixed, Affective; Disorder, Organic
- Trial name
- CLASS-BD (NCT05480150)
- Testing
- Escitalopram Oxalate Tablets, Quetiapine Fumarate Tablets, Lurasidone
- Where
- China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
Bipolar Disorder
Dialectical Behavior Therapy for Youth With and/or at Familial Risk for Bipolar Disorder
Dialectical behavior therapy (DBT) will be conducted over 1 year in youth with and/or at familial risk for bipolar disorder (BD).
- Trial name
- DB1 (NCT05153382)
- Testing
- Dialectical behavioral therapy
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Centre for Addiction and Mental Health
Bipolar Disorder
Combination Therapy for the Treatment of Bipolar Disorders
This study will compare triple and double drug regimens in the treatment of patients with depression, hypomania, or mania.
- Trial name
- NCT00063362
- Testing
- Lithium, Lamotrigine, Divalproex
- Volunteers
- 49 people
- Sponsor
- University Hospitals Cleveland Medical Center
Mood Disorders, Bipolar Disorder
Technology Enhanced Family Treatment
The investigators propose to enhance the scalability of family-focused therapy (FFT), a 12-session evidence-based therapy for youth at high risk for mood disorders, through augmentation with a novel mobile phone application…
- Conditions
- Mood Disorders, Bipolar Disorder, Major Depression
- Trial name
- NCT03913013
- Testing
- Family-Focused Treatment with MCC App
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of California, Los Angeles
Bipolar Disorder
Intranasal Ketamine In the Treatment of Pediatric Bipolar Disorder
The investigators plan to evaluate the efficacy and safety of intranasal Ketalar (ketamine hydrochloride) in the treatment of primary symptom manifestations of pediatric bipolar disorder; Fear of Harm (FOH) phenotype.
- Trial name
- IKBP (NCT01504659)
- Testing
- Ketamine hydrochloride injection, Flat tonic water (e.g., Canada Dry Tonic Water)
- Where
- 4 sites in United States
- Volunteers
- 5 people
- Sponsor
- Juvenile Bipolar Research Foundation
Bipolar Disorder, Multiple Mental Health Conditions
Narrative Enhancement and Cognitive Therapy for Self-Stigma in Youth
The goal of this pilot clinical trial is to assess the feasibility of conducting a full-scale study to learn if a new youth-adapted Narrative Enhancement and Cognitive Therapy (NECT-Y) reduces self-stigma in youth living with…
- Trial name
- NCT06672562
- Testing
- Narrative Enhancement and Cognitive Therapy, Usual care
- Where
- Canada
- Volunteers
- 97 people
- Sponsor
- Centre for Addiction and Mental Health
Bipolar Disorder, Medication Adherence
Brief Motivational Intervention to Improve Medication Adherence for Adolescents With Bipolar Disorder
Adolescence is the peak onset period for serious and persistent psychiatric disorders. Treatment guidelines for management of major psychiatric disorders in youth include pharmacotherapy.
- Trial name
- BMI (NCT03203720)
- Testing
- Brief Motivational Intervention
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Pittsburgh
Comparing Hospitalisation Time With Seroquel and Seroquel Prolong
Nis Register Study Comparing Seroquel and Seroquel Prolong
The general aim of this non interventional study is to clarify what are the current clinical treatment practices of Quetiapine Immediate Release and Quetiapine Extended Release.
- Trial name
- NCT00965536
- Where
- Finland
- Volunteers
- 200 people
- Sponsor
- AstraZeneca