Clinical trials: Birth Control
Family Planning
Misoprostol Prior to IUD Insertion in Nullipara
The use of misoprostol at a dose of 400 µg administered vaginally four hours prior to IUD insertion increased the ease of insertion and reduced the incidence of pain during the procedure, although the frequency of cramps…
- Trial name
- NCT03490617
- Testing
- Vaginal misoprostol
- Where
- Brazil
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Pregnancy, Contraception
Quick Start Approach to Birth Control Pills
Women who choose to take birth control pills are currently instructed to begin taking the pills at the end of a menstrual cycle.
- Trial name
- NCT00068848
- Testing
- Quick start oral contraceptive initiation
- Where
- 3 sites in United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Preterm Birth, Health Care Utilization
Testing Feasibility of Care Coordination and Motivational Interviewing for Women With a Recent Preterm Birth
This study continues an adaptation of care coordination to address the needs of women after preterm birth. This is a small single arm open trial designed to test intervention implementation and refine the intervention before…
- Conditions
- Preterm Birth, Health Care Utilization, Tobacco Use, Contraceptive Usage
- Trial name
- NCT05120843
- Testing
- Care coordination and motivational interviewing
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Safety
Safety, Compliance and Pharmacokinetics of Estetrol Monohydrate/Drospirenone 15/3 mg in Post-menarchal Female Adolescents
To evaluate the safety, compliance, and pharmacokinetics profile of estetrol monohydrate (E4) 15 mg combined with drospirenone (DRSP) 3 mg in post-menarchal participants between the age of 12 and 17 years + 2 months.
- Trial name
- NCT04792385
- Testing
- E4/DRSP 15/3 mg combined tablet
- Where
- 23 sites in Estonia, Finland and 4 more
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Estetra
Type 1 Diabetes
Overnight MD-Logic
Study design: Multicenter,randomized, prospective, open label, cross over, six segments, pilot trial to evaluate blood glucose control overnight under closed-loop insulin delivery with MD-Logic Artificial Pancreas (MDLAP) system…
- Trial name
- NCT01238406
- Testing
- MD-logic Artificial Pancreas (MDLAP), Standard treatment with insulin pump
- Where
- 3 sites in Germany, Israel and 1 more
- Volunteers
- 151 people
- Sponsor
- Rabin Medical Center
Immunomodulation Effect
Effect of Autologous Cord Blood-mononuclear Cells Infusion on Immune Microenvironment in Infants Born Very Preterm in NICU
Multi-omics (analysis of peripheral blood immune cells subset, peripheral blood MNCs transcriptome, soluble inflammatory cytokine profile in blood and airway secretion, lung and gut microbiota, and the interaction) analysis was…
- Trial name
- NCT05087498
- Testing
- autologous cord blood mononuclear cells, normal saline
- Where
- China
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Guangdong Women and Children Hospital
Birth Related Brachial Plexus Injury, Obstetrical Brachial Plexus Palsy
Sup-ER Protocol RCT
This study evaluates the ability of a supination and external rotation protocol to improve the arm function and anatomy of children with birth related brachial plexus injuries.
- Trial name
- NCT01933438
- Testing
- Sup-ER Protocol, Control
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- University of British Columbia
Pregnancy, Labor
Hypnosis Antenatal Training for Childbirth (HATCh): a Randomised Controlled Trial
Antenatal hypnosis is associated with a reduced need for pharmacological interventions during childbirth. This trial seeks to determine the efficacy or otherwise of antenatal group hypnosis preparation for childbirth in late…
- Trial name
- NCT00282204
- Testing
- antenatal hypnosis + audio compact disc on hypnosis, Audio compact disc on hypnosis
- Where
- Australia
- Volunteers
- 448 people
- Sponsor
- Women's and Children's Hospital, Australia
Post Menopausal Osteoporosis
Phase 2 Study of BA058 (Abaloparatide) Transdermal Delivery in Postmenopausal Women With Osteoporosis
To determine the clinical safety and efficacy of abaloparatide transdermal in otherwise healthy postmenopausal women with osteoporosis as assessed by changes in bone mineral density (BMD) and serum markers of bone metabolism when…
- Trial name
- NCT01674621
- Testing
- Abaloparatide Transdermal (50 mcg), Abaloparatide Transdermal (100 mcg), Abaloparatide Transdermal (150 mcg)
- Where
- 9 sites in United States, Denmark and 2 more
- Volunteers
- 250 people
- Sponsor
- Radius Health, Inc.
Premature Birth
Use of a Tummy Time Intervention and Parent Education in Infants Born Preterm
The purpose of this research study is to see if tummy time and parent education helps motor development among infants born preterm. Participants will be recruited from Ann and Robert H.
- Trial name
- NCT03759119
- Testing
- Tummy time and parent education, Parent education only
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Indianapolis
Infections, Rotavirus
Effectiveness of Rotarix™ Against Rotavirus Severe Gastroenteritis (RV SGE) in Infants in Panama
This study aims to estimate the effectiveness of Rotarix™ vaccine which is used nationwide as a part of the expanded program on immunization (EPI), in preventing RV SGE among hospitalised children born after 1 March 2006, which…
- Trial name
- NCT00653198
- Testing
- No intervention
- Where
- Panama
- Volunteers
- 885 people
- Sponsor
- GlaxoSmithKline
Pain
Misoprostol Prior to Intrauterine Device (IUD) Insertion in Nulliparous Women
The purpose of this study is to see if using misoprostol makes the intrauterine device insertion easier and less painful in women who have never had a baby.
- Trial name
- NCT01307111
- Testing
- Misoprostol
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Vitamin D Deficiency
Effect of Vitamin D Supplementation on Health of Low Birth Weight Infants
The purpose of this study is to determine whether a weekly supplement of vitamin D to low birth weight term infants will reduce their mortality and hospital admissions and improve their immunity.
- Trial name
- DIVIDS (NCT00415402)
- Testing
- Vitamin D3
- Where
- India
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Delhi University
Dry Eye
Safety and Efficacy Study of EGP-437 (Dexamethasone Phosphate Formulated for Ocular Iontophoresis) to Treat Dry Eye
The purpose of this study is to assess the safety and efficacy of EGP-437 (dexamethasone phosphate formulated for ocular iontophoresis) using the EyeGate® II Iontophoresis system in patients with dry eye.
- Trial name
- NCT01129856
- Testing
- Dexamethasone phosphate ophthalmic solution, Sodium citrate buffer solution
- Where
- 5 sites in United States
- Volunteers
- 198 people
- Sponsor
- Eyegate Pharmaceuticals, Inc.
Post Partum Hemorrhage
A Pragmatic Randomized Controlled Trial to Predict Postpartum Hemorrhage
This research project aims to enhance the safety of childbirth by using advanced computer models to predict the risk of postpartum hemorrhage (PPH). PPH is a significant concern for mothers during and after delivery.
- Trial name
- NCT06513351
- Testing
- Novel PPH Risk Prediction Model - Comparator Arm B
- Where
- United States
- Volunteers
- 12,500 people
- Sponsor
- Holly Ende
Patent Ductus Arteriosus After Premature Birth
PDA Treatment With Ibuprofen and Changes in Tissue Oxygenation.
Babies who are born very prematurely are often born with murmurs in the heart. In preterm babies, one of the most common causes of murmur is the presence of a PDA.
- Trial name
- NCT05325177
- Testing
- Standard Dose Ibuprofen, High Dose Ibuprofen
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Ottawa Hospital Research Institute
Muscular Dystrophies, Muscular Dystrophy, Duchenne
A Study of CAP-1002 in Ambulatory and Non-Ambulatory Patients With Duchenne Muscular Dystrophy
HOPE-2 is a double-blind clinical trial evaluating the safety and efficacy of a cell therapy called CAP-1002 in study participants with Duchenne Muscular Dystrophy (DMD).
- Conditions
- Muscular Dystrophies, Muscular Dystrophy, Duchenne, Muscular Disorders, Atrophic, Muscular Diseases
- Trial name
- HOPE-2 (NCT03406780)
- Testing
- CAP-1002
- Where
- 9 sites in United States
- Volunteers
- 20 people
- Sponsor
- Capricor Inc.
Postpartum Hemorrhage
The Impact of "Natural" Cesarean Delivery on Peripartum Maternal Blood Loss.
Throughout the history, the neonate was dependent on maternal touch and care for survival. In modern obstetrics, with hospital care the neonates are seldom separated from their mothers after delivery.
- Trial name
- NCT02768142
- Testing
- Natural cesarean delivery, Standard cesarean delivery
- Where
- Israel
- Volunteers
- 214 people
- Sponsor
- Raed Salim
Stillbirth, Neonatal Death
Intermittent Auscultation Using Handheld Doppler: a Randomized Controlled Trial Comparing Perinatal Outcomes in Uganda
A novel handheld Doppler has been developed which is rugged and is powered only by a hand crank. This study aims to test the use of this Doppler versus the Pinard horn to monitor the fetal heart rate in labour in a hospital…
- Trial name
- NCT02273037
- Testing
- Fetal heart rate Doppler, Partograph
- Where
- 2 sites in Canada, Uganda
- Volunteers
- 1,987 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Infant, Premature, Diseases, Infant, Newborn, Disease
Noninvasive High Frequency Oscillatory Ventilation as a Post-extubation Respiratory Support in Neonates
A randomized controlled trial comparing Noninvasive high frequency oscillatory ventilation (NHFOV) and Noninvasive positive pressure ventilation (NIPPV) as post-extubation respiratory support in preterm neonates with respiratory…
- Conditions
- Infant, Premature, Diseases, Infant, Newborn, Disease, Respiratory Tract Diseases, RDS
- Trial name
- NCT05493527
- Testing
- noninvasive high frequency oscillatory ventilation, noninvasive positive pressure ventilation
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
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