Clinical trials: Blepharitis
Blepharitis
A Phase 3 Study to Evaluate the Efficacy and Safety of Pimecrolimus 0.3% Ophthalmic Ointment
The objective of this study is to determine the efficacy and safety of Pimecrolimus 0.3% (MR-139) Ophthalmic Ointment.
- Trial name
- NCT06400511
- Testing
- Pimecrolimus 0.3% Ophthalmic Ointment
- Where
- 29 sites in United States
- Volunteers
- 477 people
- Sponsor
- Famy Life Sciences, a Viatris Company
Corneal Infiltrates
A Phase II Study of Moxidex Ophthalmic Solution for Treatment of Marginal Corneal Infiltrates
The purpose of the study is to determine whether Moxidex ophthalmic solution is safe and effective in treating marginal corneal infiltrates.
- Trial name
- NCT00579020
- Testing
- Moxifloxacin/dexamethasone phosphate ophthalmic solution, Moxifloxacin ophthalmic solution 0.5%, Dexamethasone phosphate solution, 0.1%
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Alcon Research
Blepharitis
A Four Week Study of Azithromycin Ophthalmic Solution, 1% Versus Vehicle in Subjects With Blepharitis (P08636)
The purpose of this study is to compare the safety and efficacy of azithromycin ophthalmic solution, 1% versus vehicle over a four-week treatment period in treating the signs and symptoms of subjects with blepharitis and to…
- Trial name
- NCT01269658
- Testing
- Azithromycin ophthalmic solution, 1%, Vehicle
- Volunteers
- 40 people
- Sponsor
- Merck Sharp & Dohme LLC
Chronic Blepharitis
Demodex Blepharitis Treatment Study
This is a randomized clinical trial to determine the safety and efficacy of terpinen-4-ol (T4O), the most active ingredient of tea tree oil (TTO), in eradicating ocular demodicosis (reducing ocular demodex counts and achieving…
- Trial name
- DBTS (NCT01647217)
- Testing
- Terpinen-4-ol
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- BioTissue Holdings, Inc
Sebaceous Gland Diseases, Blepharitis
Efficacy of iLid Cleanser (Avenova) Versus Vehicle on Ocular Skin Flora
This study is designed to evaluate the effect of Novabay iLid Cleanser, as compared to its Vehicle, on the ocular skin flora. In the pre-randomization phase, subjects will receive a single application of open-label NovaBay iLid…
- Trial name
- NCT02455895
- Testing
- iLid Cleanser
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- NovaBay Pharmaceuticals, Inc.
Active, Symptomatic Blepharitis
Comparative Study to Evaluate ISV-305 Compared to Vehicle in Blepharitis Subjects
The purpose of this study is to evaluate the clinical efficacy and safety of ISV-305 (Dexamethasone in DuraSite® 2) compared to Vehicle in the treatment of subjects with active, symptomatic Blepharitis.
- Trial name
- ISV-305 (NCT01543490)
- Testing
- ISV-305, Vehicle
- Where
- United States
- Volunteers
- 558 people
- Sponsor
- Sun Pharmaceutical Industries Limited
Blepharitis
A Phase 2, Controlled, Double Blind, Randomized and Multicenter Study to Compare Efficacy and Safety of a Novel Topical Therapy (APT-001, Spinosad 1.8%) in Patients With Blepharitis.
The purpose of this study is to establish the clinical efficacy of APT-001 topical therapy 1.8% in patients with blepharitis as compared to its vehicle control, and to establish that the therapeutic is safe and generally well…
- Trial name
- VISTA-1 (NCT06720896)
- Testing
- APT-001 topical ophthalmic ointment (spinosad), Vehicle control for APT-001 topical ophthalmic ointment
- Where
- 2 sites in Guatemala
- Volunteers
- 66 people
- Sponsor
- Aperta Biosciences, LLC
Demodex Blepharitis
Efficacy and Tolerability of Blephademodex Wipes
Primary Objective To evaluate efficacy of Blephademodex eyelid hygiene wipe treatment with a subsequent maintenance period with Blephaclean lid cleansing wipes in Demodex blepharitis, as assessed by the change in ocular symptoms…
- Trial name
- NCT04780165
- Testing
- Blephademodex
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Laboratoires Thea