Clinical trials: Block
Skeletal Class II Malocclusion
Assesment of Tempromandibular Joint ( TMJ ) Changes After Treatment of Skeletal Class II Cases by Twinblock vs Monoblock Appliances
Assesment of TMJ changes after treatment of skeletal classII growing patients by Twinblock vs Mono block applinces
- Trial name
- NCT07270653
- Testing
- twin block, Mono block
- Where
- Egypt
- Volunteers
- 18 people
- Sponsor
- Faculty of Dental Medicine for Girls
Immune Responses, Post Operative Recovery
Comparative Study Between the Effects of Deep Versus Moderate Neuromuscular Blockade on Postoperative Recovery and Immune Function in Patients Undergoing Total Hip Replacement Surgery.
. The investigators hypothesized that DNMB ( Deep NeuroMuscular Block) would yield superior postoperative recovery quality and attenuate the surgery-induced immune suppression compared to MNMB ( Moderate NeuroMuscular Block)in…
- Trial name
- NCT07870954
- Testing
- ToF ( Train of Four) Scan
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Aortic Stenosis
SOURCE 3: Observational Study to Evaluate Safety and Performance of SAPIEN 3 THV System in Real Life Practice
This is an international, mutli-center, prospective, consecutively enrolled, observational registry. 2000 patients are planned to be enrolled over one year at up to 150 participating sites.
- Trial name
- SOURCE 3 (NCT02698956)
- Testing
- TAVI (Transcatheter Aortic Valve Implantation)
- Where
- 73 sites in Denmark, Finland and 8 more
- Volunteers
- 2,000 people
- Sponsor
- Edwards Lifesciences
Trauma-related Wound, Head Injury
Teaching First Aid and Trauma Management to School Students
This proposal aims to describe research that will utilize first aid in primary education students and will attempt to identify the frequency with which the training should be repeated and the type of trainer who will carry out…
- Conditions
- Trauma-related Wound, Head Injury, Choking, Nose Bleed
- Trial name
- NCT05563129
- Testing
- First aid lessons
- Where
- Greece
- Volunteers
- 192 people
- Sponsor
- University of Ioannina
Regional Anesthesia Morbidity
Comparison of Femoral Nerve Block Versus Fascia Iliaca Compartment Block for Pain Control in Traumatic Femur Fracture Repair in Pediatric Population
Pediatric orthopedic surgical procedures require a multimodal approach for anesthetic management that maximizes both patient comfort and safety.
- Trial name
- NCT05882201
- Testing
- Fascia Iliaca compartment block group, Femoral nerve block group, General care
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Menoufia University
Exercise Induced Asthma, Exercise Induced Pharyngeal Collapse
Diagnostics and Quality of Life With EIA and EILO
The purpose of this study is to investigate the quality of life of subjects suffering from dyspnoea while exercising and quantify the number of diagnoses of Exercise induced Asthma (EIA) and Exercise induced laryngeal obstruction…
- Trial name
- NCT03550456
- Testing
- ECC, ECC with CLE, Speech therapy
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Colonic Neoplasms, Colorectal Neoplasms
Study of an Individualized Vaccine Targeting Neoantigens in Combination With Immune Checkpoint Blockade for Patients With Colon Cancer
The primary objective is to assess and characterize the antitumor activity and safety and tolerability of adjuvant treatment with an individualized neoantigen vaccine called GRT-C901/GRT-R902 (chimpanzee adenovirus [ChAd] and…
- Trial name
- NCT05456165
- Testing
- GRT-C901, GRT-R902, Atezolizumab
- Where
- 3 sites in United States
- Sponsor
- Gritstone bio, Inc.
Children
Reduction in MACbar of Sevoflurane by Dexmedetomidine in Children
The study was designed to define the interaction of intravenous infusion of dexmedetomidine, an a2-adrenergic agonist, and sevoflurane in children having surgery by using the minimum alveolar concentration which can block…
- Trial name
- NCT02261675
- Testing
- dexmedetomidine
- Volunteers
- 63 people
- Sponsor
- Cai Li
Plasmodium Falciparum Malaria
Assessing the Safety, Immunogenicity and Ex-vivo Efficacy of Two Candidate Malaria Transmission Blocking Vaccines, Pfs25-IMX313 and Pfs45/48 Administered Alone and in Combination, in Matrix-M Adjuvant
Assessing the safety, immunogenicity and ex-vivo efficacy of two transmission blocking vaccines (Pfs25-IMX313 in Matrix M and Pfs48/45 in Matrix M alone and co-administered) in Burkina Faso, in 18-45 years, 12-17 years and 05-11…
- Trial name
- NCT06549257
- Testing
- Pfs25-IMX313, Pfs48/45
- Where
- Burkina Faso
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Hemorrhoids, Anal Fissure and Fistula
Pudendal Nerve Block With Bupivacaine Alone and Bupivacaine With Methylene Blue for Postoperative Analgesia
Study Description: The goal of this clinical trial is to compare the duration of postoperative pain relief achieved with two different approaches to pudendal nerve block in patients undergoing elective perianal surgery.
- Conditions
- Hemorrhoids, Anal Fissure and Fistula, Perianal Abscess, Perianal Fistula
- Trial name
- NCT05990569
- Testing
- Ultrasound guided Pudendal nerve block
- Where
- Nepal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nepal Mediciti Hospital
Wet Age Related Macular Degeneration, Diabetic Macular Edema, Retinal Vein Occlusion, Wet Age Related Macular Degeneration
Observe the Effectiveness and Safety of Ranibizumab in Real Life Setting
This study will describe the long-term safety and effectiveness, treatment patterns,and patient reported quality of life associated with ranibizumab treatment in routine clinical practice for all approved indication included in…
- Conditions
- Wet Age Related Macular Degeneration, Diabetic Macular Edema, Retinal Vein Occlusion, Wet Age Related Macular Degeneration, Diabetic Macular Edema, Retinal Vein Occlusion
- Trial name
- LUMINOUS (NCT01318941)
- Testing
- Ranibizumab
- Where
- 463 sites in Argentina, Australia and 41 more
- Volunteers
- 30,490 people
- Sponsor
- Novartis Pharmaceuticals
Lower Abdominal Surgery
Erector Spinae Plane Block for Peroperative Analgesia and Intraabdominal Tissue Oxygenation
Brief summary: Regional anesthesia decreases the need for intravenous analgesia in the peri-operative period. Erector spinae plane (ESP) is a regional anesthesia technique shown to be effective at the dorsal and ventral rami of…
- Trial name
- ESPB (NCT03808129)
- Testing
- Bupivacaine and Lidocaine
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Benign Prostate Hypertrophy(BPH)
Transurethral Focal Laser Ablation Versus Transurethral Prostatectomy For Management Of Benign Prostatic Obstruction
Introduction and objectives: Laser prostatectomy has become an increasingly popular and effective alternative to transurethral resection of the prostate (TURP) for the treatment of benign prostatic hyperplasia (BPH).-.
- Trial name
- NCT07196475
- Testing
- FOCAL LASER ABLATION OF PROSTATE
- Where
- Egypt
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Coronary Disease, Coronary Artery Disease
XIENCE V® Everolimus Eluting Coronary Stent System India Post-marketing Single-arm Study
XIENCE V® India is a prospective, open-label, multi-center, observational, single-arm study to evaluate XIENCE V® EECSS continued safety and effectiveness during commercial use in real world settings.
- Conditions
- Coronary Disease, Coronary Artery Disease, Coronary Restenosis
- Trial name
- XIENCE V India (NCT00631228)
- Testing
- XIENCE V® Everolimus Eluting Coronary Stent
- Where
- 18 sites in India
- Volunteers
- 1,000 people
- Sponsor
- Abbott Medical Devices
Analgesia
Opioid Free Anesthesia for Laparoscopic Cholecystectomy
The goal of this interventional study is to check the efficacy of Erector Spinae block as Opioid Free Anesthesia for Laparoscopic Cholecystectomy. Laparoscopic Cholecystectomy is a commonly performed day care procedure.
- Trial name
- NCT06202664
- Testing
- Erector Spinae Block, Opioid Analgesic
- Where
- Pakistan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Muhammad Haroon Anwar
Intensive Care Units, Neonatal, Misadventures to Patients During Surgical and Medical Care
SEPREVEN: a Stepped-wedge Randomised Controlled Trial
Adverse events are frequent in Neonatal Intensive Care Units' (NICU) patients and account for a high morbidity and mortality. Possible severe adverse events are central line associated bloodstream infections (CLABSI), ventilator…
- Conditions
- Intensive Care Units, Neonatal, Misadventures to Patients During Surgical and Medical Care, Catheter-related Bloodstream Infection (CRBSI) Nos, Quality of Healthcare
- Trial name
- SEPREVEN (NCT02598609)
- Testing
- Education program for NICU caregivers
- Where
- 12 sites in France
- Volunteers
- 8,000 people
- Sponsor
- Dr Caeymaex Laurence
Appendectomy, Laparoscopy
TAP Block or Wound Infiltration for Laparoscopic Pediatric Appendectomy: a Pilot Study
Effectiveness of the TAP block compared to wound infiltration in controlling pain after laparoscopic appendectomy in children
- Conditions
- Appendectomy, Laparoscopy, Anesthesia, Conduction, Child, Preschool
- Trial name
- NCT04294537
- Testing
- TAP Block, LIA local infiltration, General anesthesia
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Ospedale di Circolo - Fondazione Macchi
Age-related Macular Degeneration (AMD), Central Retinal Vein Occlusion (CRVO)
Evaluation of Physician Knowledge of Safety and Safe Use Information for Aflibercept in Canada
The primary objective of this study is to measure physician knowledge and understanding of the key safety information contained in the Eylea vial preparation instruction card, the intravitreal injection procedure video, and the…
- Conditions
- Age-related Macular Degeneration (AMD), Central Retinal Vein Occlusion (CRVO), Diabetic Macular Edema (DME)
- Trial name
- NCT02585401
- Testing
- Eylea (Aflibercept, VEGF Trap-Eye, BAY86-5321)
- Where
- Canada
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Bayer
Class II Malocclusion
Effectiveness of Modified Functional Appliance With Expander
This clinical trial compares the effectiveness of a myofunctional appliance that uses a clear and modified twin block appliance with an expander made from 2mm biocompatible polyethylene terephthalate modified with Glycol…
- Trial name
- NCT06116500
- Testing
- Modified twin block appliance with expander, Conventional twin block appliance with expander
- Where
- Iraq
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Persistent Allergic Rhinitis
Oxymetazoline Bridge Therapy With Intranasal Corticosteroids in Pediatric Allergic Rhinitis
Persistent allergic rhinitis in children is commonly treated with intranasal corticosteroids (INS), which are considered first-line therapy.
- Trial name
- NCT07593898
- Testing
- Mometasone Furoate (MF) Metered Dose Inhaler (MDI), 100 mcg, Oxymetazoline 0.05% nasal solution
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Dr. Behcet Uz Children's Hospital
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