Clinical trials: Block
Stroke, Ischemic Stroke
Gravity Stroke System for Recanalization of Large Vessel Occlusion Strokes
Supernova and Neutron are endovascular mechanical revascularization devices indicated to restore blood flow by removing thrombus from a large intracranial vessel in patients experiencing an acute ischemic stroke within 24 hours…
- Conditions
- Stroke, Ischemic Stroke, Cerebrovascular Disorders, Brain Diseases
- Trial name
- GRASSROOT Reg (NCT07335185)
- Testing
- Supernova revascularization device
- Volunteers
- 3,000 people
- Sponsor
- Gravity Medical Technology, INC
Postoperative Pain
Effect of a Sciatic Block (SNB) Combined With a Continuous Femoral Block (CFNB) on Pain Scores After Knee Arthroplasty
The purpose of this study is to determine if the addition of a sciatic nerve block (SNB) to a continuous femoral nerve block (CFNB) improves post-operative analgesia after knee arthroplasty.
- Trial name
- NCT01337115
- Testing
- SNB plus CFNB, CFNB
- Where
- Portugal
- Volunteers
- 50 people
- Sponsor
- Centro Hospitalar do Porto
Congenital Heart Disease in Children, Neurologic Complication
Erector Spinae Plane Block in Congenital Heart Disease Patients
Pediatric cardiac patients undergoing surgical anesthesia are at an increased risk of poor neurologic outcome (20-50%). Unattenuated anesthetic exposure and pain contributes to physiologic perturbations that may increase…
- Trial name
- NCT04158024
- Testing
- Erector Spinae Plane Block
- Volunteers
- 150 people
- Sponsor
- Stanford University
Macular Degeneration, Neovascularization, Pathologic
Branch Vein Occlusion Study
To determine whether scatter argon laser photocoagulation can prevent the development of neovascularization. To determine whether peripheral scatter argon laser photocoagulation can prevent vitreous hemorrhage.
- Conditions
- Macular Degeneration, Neovascularization, Pathologic, Vitreous Hemorrhage
- Trial name
- NCT00000162
- Testing
- Macular Argon Laser Photocoagulation, Peripheral Scatter Argon Laser Photocoagulation, Scatter Argon Laser Photocoagulation
- Sponsor
- National Eye Institute (NEI)
Burns
Ultrasound-Guided Block of the Lateral Femoral Cutaneous Nerve in Pediatric Patients
The purpose of this study is to determine whether either a peripheral nerve block under ultrasound (u/s) guidance of the lateral femoral cutaneous nerve (LFCN), versus an u/s guided block of the nerve followed by continuous…
- Trial name
- NCT01500655
- Testing
- Regional nerve block, Catheter
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Massachusetts General Hospital
Hypotonia, Muscle, Obstructive Sleep Apnea
Long-term Evaluation of Nasopharyngeal Airway in Hypotonia
This research is studying the long term use of a nasal airway device (self-supporting nasopharyngeal airway; "ssNPA") in children with hypotonic upper airway obstruction to learn about its effectiveness and tolerability as a…
- Conditions
- Hypotonia, Muscle, Obstructive Sleep Apnea, Nasal Airway Obstruction
- Trial name
- NCT06614582
- Testing
- Self-Supporting Nasopharyngeal Airway (ssNPA)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Michigan
Intestinal Pseudo-Obstruction, Short Bowel Syndrome
Improved Quality of Life in Children With Intestinal Failure
Children with intestinal failure have a lack of tolerance for food in the intestine. The children are dependent on intravenous nutrition over a long period of time period to ensure growth and development.
- Conditions
- Intestinal Pseudo-Obstruction, Short Bowel Syndrome, Malabsorption Syndrome Autoimmune Enteropathy, Bacterial Overgrowth
- Trial name
- NCT04981262
- Testing
- Stimulance
- Where
- Norway
- Volunteers
- 56 people
- Sponsor
- Oslo University Hospital
Pyloric Stenosis
Post-Operative Impact of Nasogastric Tubes on Rates of Emesis in Infants Diagnosed With Pyloric Stenosis
The overall objective of this research study is to determine the effect of a pre-operatively placed nasogastric tube compared to no nasogastric tube, on post-operative emesis rates and postoperative length of stay in infants with…
- Trial name
- POINTS (NCT01139853)
- Testing
- Nasogastric Tube
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Hamilton Health Sciences Corporation
Retinitis Pigmentosa, Maculopathy, Age Related
High Resolution Retina Imaging
To increase the clinical experience of using the rtx1 camera in various retinal disorders and to follow the evolution of structural alterations during retinal diseases using adaptive optics imaging with the rtx1 camera
- Conditions
- Retinitis Pigmentosa, Maculopathy, Age Related, Macular Dystrophy, Macular Edema
- Trial name
- IHR (NCT04128150)
- Where
- 3 sites in France
- Volunteers
- 1,000 people
- Sponsor
- Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
Hip Fracture
Single Shot Fascia Iliaca Block vs Femoral Nerve Block for Analgesia for Surgical Fixation of Hip Fractures
Hip fractures are common in our elderly population and is associated with pain before and after surgery. The current pain management for patients who have undergone surgery for hip fractures include a combination of oral…
- Trial name
- NCT02330302
- Testing
- Ropivacaine
- Where
- Singapore
- Volunteers
- 30 people
- Sponsor
- Changi General Hospital
Sleep Disturbance
Blocking Blue Light in Pregnancy, Effects on Melatonin Profile and Sleep
Sleep disturbances are common in pregnancy, and the incidence increases during the third trimester. Light and specially the blue wavelengths of light, is affecting sleep and the circadian rhythm.
- Trial name
- NCT03114072
- Testing
- Blue-blocking glasses, Light grey control glasses
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- University of Bergen
Superior Mesenteric Artery Syndrome, Somatic Symptom Disorder (DSM-5)
Fluoxetine in Refractory Superior Mesenteric Artery Syndrome by Targeting Comorbid Somatic Symptom Disorder
The goal of this interventional study is to evaluate whether fluoxetine, a selective serotonin reuptake inhibitor (SSRI), can alleviate core symptoms and reduce the need for surgical intervention in patients with refractory…
- Trial name
- NCT07115472
- Testing
- Fluoxetine
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Xijing Hospital of Digestive Diseases
NEC, Gastroschisis
Neokare Safety and Tolerability Assessment in Neonates With GI Problems
With an increasing body of evidence to support a causal link between drinking milk that contain cow's milk protein (CMP) and the development of gastrointestinal disturbance in infants, many clinicians avoid the use of CMP…
- Conditions
- NEC, Gastroschisis, Intestinal Perforation, Atresia, Intestinal
- Trial name
- NCT05293353
- Testing
- NeoKare Breast Milk Fortifier
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Ureteropelvic Junction Obstruction, Hypospadias
Effect of Oxybutynin on Opioid Use After Urologic Surgery in Children
The goal of this clinical trial is to determine whether giving oxybutynin before urologic reconstruction surgery reduces the amount of opioid pain medication needed in children.
- Trial name
- NCT07911137
- Testing
- Oxybutynin
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- University of Calgary
Pyloric Stenosis
Changes in Cerebral Oxygenation During Laparoscopic Pyloromyotomy
A prospective study that will assess the effect of laparoscopy on tissue oxygenation in the patients undergoing a laparoscopic pyloromyotomy at Nationwide Children's Hospital.
- Trial name
- NCT03650842
- Testing
- Near infrared spectroscopy (NIRS)
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Nationwide Children's Hospital
Pain Assessment
Effect of Starpen CCLAD in Injection and Extraction
The present study aims to evaluate the effect of computer-controlled Starpen automatic injection device versus the traditional syringe on pain perception during Injection of nerve block anesthesia and extraction of mandibular…
- Trial name
- Starpen CCLAD (NCT06827223)
- Testing
- computer-controlled Starpen Automatic Injection Device, Traditional Syringe
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Cairo University
Umbilical Hernia
Caudal Versus Rectus Sheath Study
The literature has clearly demonstrated that the effective treatment of postoperative pain in infants and children is challenging.
- Trial name
- NCT01394523
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Nationwide Children's Hospital
Local Anesthetic Infiltration, Topical Anesthesia
Topical Cryoanesthesia Versus Benzocaine in Pediatric Dentistry
This clinical study tested and compared two ways (cold-base technique or "cryoanesthesia" and conventional benzocaine gel) to reduce pain from dental injections in children.
- Conditions
- Local Anesthetic Infiltration, Topical Anesthesia, Pain Perception
- Trial name
- No acronym (NCT07351383)
- Testing
- Local Anesthesia (lidocaine hydrochloride)
- Where
- Mexico
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de San Luis Potosí
Acute Appendicitis, Acute Cholecystitis
Web-based International Register of Emergency Surgery and Trauma
The WIRES-T project (Web-based International Registry of Emergency General Surgery and Trauma) has been set up to allow to all the EGS (Emergency General Surgery) and Trauma surgeons to register their activity and to obtain a…
- Conditions
- Acute Appendicitis, Acute Cholecystitis, Acute Diverticulitis, Post-operative Complications
- Trial name
- WIRES-T (NCT03643718)
- Testing
- Emergency General Surgery
- Where
- Italy
- Volunteers
- 10,000 people
- Sponsor
- A.O. Ospedale Papa Giovanni XXIII
Neuromuscular Blockade
Neuromuscular Monitoring in Children (6 Months - 2 Years) With Electromyography and Acceleromyography
The aim of this study is to compare AMG and EMG (Philips IntelliVue NMT module and Senzime TetraGraph) in the objective monitoring of neuromuscular blocking in children between the age of 6 months and 2 years.The monitoring will…
- Trial name
- NCT06409260
- Testing
- Acceleromyography (AMG), Electromyography (EMG)
- Where
- Denmark
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Matias Vested
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