Clinical trials: Block
Bile Duct Neoplasms Malignant
Stenting Malignant Jaundice for Quality of Life
Endoscopic stent insertion is considered the method of choice for palliation of malignant bile duct obstruction (MBDO). However, it can cause complications and requires periodic stent exchanges.
- Trial name
- NCT01459965
- Testing
- ERCP with 10 French biliary plastic stent placement, ERCP with 11.5 French biliary plastic stent
- Volunteers
- 164 people
- Sponsor
- Indiana University
Ultrasound Imaging, Caudal Block
Out Of-plane Technique Against In-plane for Caudal Block
Caudal block is an easy and effective type of central neuraxial block that is widely used in subumbilical surgeries to provide intraoperative and postoperative analgesia in the pediatric population.
- Conditions
- Ultrasound Imaging, Caudal Block, Hypospadias
- Trial name
- NCT04671992
- Testing
- Out of-Plane Technique and In-Plane on
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Lower Urinary Tract Symptoms, Benign Prostate Hyperplasia
Registry: TPLA for LUTS
Rationale: The treatment of lower urinary tract symptoms (LUTS) due to benign prostatic enlargement in men with transperineal laser ablation (TPLA) may offer advantages in functional outcomes and safety over current standard…
- Conditions
- Lower Urinary Tract Symptoms, Benign Prostate Hyperplasia, Benign Prostatic Hypertrophy With Outflow Obstruction
- Trial name
- NCT03776006
- Testing
- Transperineal Laser Ablation
- Volunteers
- 500 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Orthodontic Appliance Complication, Malocclusion, Angle Class II, Division 1
Mini-implant-supported Twin-Block in Treating Patients With Class II Division 1 Malocclusion
Correcting the skeletal class II using functional appliances, whether removable or fixed, always leads to skeletal and alveolar effects.
- Trial name
- NCT06403033
- Testing
- Mini-implant-supported Twin-Block, Twin-Block
- Where
- Syria
- Volunteers
- 41 people
- Sponsor
- Damascus University
ARDS, Lung Protective Ventilation
Effect of Different Depths of Neuromuscular Blockade on Respiratory Mechanics in Patients With Moderate-severe Acute Respiratory Distress Syndrome
Acute respiratory distress syndrome (ARDS) is characterized by acute diffuse alveolar injury caused by a variety of pulmonary and extrapulmonary factors, leading to refractory hypoxemia. It has high incidence and mortality rates.
- Trial name
- ARDS (NCT06514209)
- Testing
- cisatracurium
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Southeast University, China
Chronic Daily Headache, Post-Traumatic Headache
Assessment of the Efficacy of the Transnasal Sphenopalatine Ganglion Block in the Treatment of Chronic Daily Headache in Children and Adolescents.
Primary Objective The primary objective of the study is to assess whether transnasal sphenopalatine ganglion block using the device TX360 reduces intensity and severity of the Post-Traumatic Headache in adolescents.
- Trial name
- SPG (NCT05213065)
- Testing
- Sphenopalatine ganglion block with 0.5% bupivacaine, Sphenopalatine ganglion block with saline
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Pablo Ingelmo
Acute Ischemic Stroke
Registration of Acute Ischemic Stroke With Large and Medium-sized Vascular Occlusion in Southwest China(LMVOS)
This study is designed to observe the treatment options in real-world clinical practice as well as the safety and efficacy of different treatment strategies.
- Trial name
- LMVOS (NCT06125236)
- Testing
- Visit at D90
- Where
- China
- Volunteers
- 8,000 people
- Sponsor
- Zhengzhou Yuan
Macular Edema, Retinal Vein Occlusion
Retrospective Data Collection Study in Patients With Macular Oedema Receiving OZURDEX®
This study will use retrospective data to evaluate the safety and efficacy of OZURDEX® (dexamethasone intravitreal implant 0.7 mg) in the treatment of macular oedema due to retinal vein occlusion (RVO) in clinical practice.
- Trial name
- NCT02181530
- Testing
- No Intervention
- Where
- Poland
- Volunteers
- 43 people
- Sponsor
- Allergan
Postoperative Pain, Caudal Anesthesia
Effect of Intravenous Versus Caudal Dexmedetomidine on Perfusion Index and Hemodynamic Responses in Children Undergoing Infraumbilical Surgery
Caudal anesthesia is widely used to provide pain relief for children undergoing surgery below the navel (infraumbilical surgery).
- Conditions
- Postoperative Pain, Caudal Anesthesia, Peripheral Perfusion, Pediatric Surgery
- Trial name
- NCT07852039
- Testing
- Caudal Dexmedetomidine, Intravenous Dexmedetomidine
- Volunteers
- 100 people
- Sponsor
- Assiut University
Postoperative Pain, Acute
EOI Block in Otoplasty With Rib Cartilage Graft
This randomized controlled trial aims to evaluate the effect of ultrasound-guided external oblique intercostal (EOI) fascial plane block on postoperative pain control and recovery in pediatric patients undergoing otoplasty with…
- Trial name
- NCT07262944
- Testing
- Ultrasound-guided External Oblique Intercostal (EOI) Fascial Plane Block, Standard postoperative pain management (no EOI block)
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul National University Hospital
Diaphragmatic Paralysis
Ultrasound-guided Interscalene Block:3mL Ropi Provide Similar Analgesia to 5mL and Less Diaphragmatic Paralysis
Ropivacaine for ultrasound-guided interscalene block: 3mL provide similar analgesia to 5mL with less diaphragmatic paralysis in shoulder arthroscopy surgeries
- Trial name
- NCT04317235
- Testing
- Ropivacaine 0.5% Injectable Solution
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Saint George Hospital
Anesthesia, General, Neuromuscular Blockade
Pharmacokinetic-pharmacodynamic Analysis of Sugammadex in Children
This study administers sugammadex sodium to pediatric patients under general anesthesia with rocuronium. Pharmacokinetic and pharmacodynamic analysis are performed based on plasma concentration of sugammadex sodium and monitoring…
- Trial name
- NCT03943888
- Testing
- Sugammadex Injection 2mg/kg, Sugammadex Injection 4mg/kg, Sugammadex Injection 8mg/kg
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul National University Hospital
Gastrostomy
EOI Block for Laparoscopic Gastrostomy
This randomized controlled trial will evaluate the efficacy of ultrasound-guided external oblique intercostal fascial plane (EOI) block in reducing intraoperative and postoperative pain in pediatric patients undergoing…
- Trial name
- NCT07119346
- Testing
- EOI block
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul National University Hospital
Acute Appendicitis
TAP Block for Laparoscopic Appendicectomy in Adults
Laparoscopic (key-hole) appendicectomy is a minimally invasive procedure when compared to open large bowel resection, but is still associated with a significant amount of pain and discomfort.
- Trial name
- NCT03252561
- Testing
- Ultrasound guided Transversus Abdominis Plane (TAP) bock, Local anaesthetic infiltration of laparoscopic port sites
- Where
- United Kingdom
- Sponsor
- Oxford University Hospitals NHS Trust
Inferior Alveolar Nerve Block in Children
Clinical Success of 12 mm Needle IANB in Children
This prospective single-arm pilot study will evaluate the clinical success of an inferior alveolar nerve block performed using a 12 mm 30-gauge extra-short dental needle in children aged 4 to 12 years.
- Trial name
- NCT07791082
- Testing
- 12 mm 30-Gauge Extra-Short Dental Needle
- Where
- Egypt
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Natural Killer/T-Cell Lymphoma, Nasal and Nasal-Type
Treatment of Relapsed or Refractory Natural Killer/T Cell Lymphoma
The purpose of this study is to evaluate the efficacy and safety of PD-1 blockade pembrolizumab for patients with relapsed or refractory Natural Killer(NK)/T Cell Lymphoma.
- Trial name
- NCT03107962
- Testing
- Pembrolizumab (PD-1 Blocking Antibody)
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Mingzhi Zhang
Pain, Postoperative, Anterior Cruciate Ligament Injuries
IPACK on Early Pain Scores After ACL Reconstruction
The goal of this clinical trial is to learn whether using an anesthetic technique called IPACK block will control pain after ACL reconstruction surgery.
- Conditions
- Pain, Postoperative, Anterior Cruciate Ligament Injuries, Analgesics, Opioid
- Trial name
- NCT05985629
- Testing
- IPACK
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Loyola University
Aortic Stenosis, Cardiomyopathy, Hypertrophic
PARTNER II Trial: Placement of AoRTic TraNscathetER Valves II - Nested Registry 3/Valve-in-Valve
To assess the safety and effectiveness of the SAPIEN XT transcatheter heart valve in patients with a failing surgical aortic bioprosthetic valve.
- Trial name
- PII NR3/ViV (NCT03225001)
- Testing
- Edwards SAPIEN XT transcatheter valve, Model 9300TFX
- Where
- 47 sites in United States, Canada
- Volunteers
- 197 people
- Sponsor
- Edwards Lifesciences
Brachial Plexus Injury
Incidence of Brachial Plexus Injury After Rotator Cuff Repair With Continuous Interscalene Block
Brachial plexus injury after shoulder surgery with continuous interscalene block is 2.4% at 1 month and 0% at 6 months, but may be higher with a systematic postoperative neurological examination.
- Trial name
- NCT01334632
- Testing
- Continuous interscalene block, PCA morphine
- Where
- Switzerland
- Volunteers
- healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Postoperative Pain
Fascia Iliaca Block Supplemented With Perineural Vs Intravenous Dexamethasone
Split-thickness skin grafting is the current standard of care for the reconstructive procedures in managing burn injuries and traumatic tissue defects.
- Trial name
- Interventional (NCT04561856)
- Testing
- Dexamethasone
- Volunteers
- 99 people
- Sponsor
- Assiut University
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