Clinical trials: Blockades Neuromuscular
Anesthesia Intubation Complication
Propofol for Pediatric Tracheal Intubation With Deep Anesthesia During Sevoflurane Induction
The purpose of this study is to determine the amount of propofol required to achieve 50% of patients obtaining a perfect ("excellent") intubation score of 5 on the Steyn modification of the Helbo-Hansen Intubation Score, when…
- Trial name
- NCT01150838
- Testing
- propofol
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- University of Virginia
Anxiety, Stress
Feasibility Study on the Effect of Complementary Methods as Supportive Interventions for Parents of Children With Cancer
The purpose of this study is to determine whether Guided Imagery and Progressive Muscle relaxation are effective as stress reducing techniques in parents of hospitalized children with cancer.
- Conditions
- Anxiety, Stress, Mood, Coping
- Trial name
- NCT01590524
- Testing
- Guided Imagery and Progressive Muscle Relaxation
- Where
- Cyprus
- Volunteers
- 52 people
- Sponsor
- Cyprus University of Technology
Adenovirus, Anesthesia
Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care
Understudied drugs will be administered to children per standard of care as prescribed by their treating caregiver and only biological sample collection during the time of drug administration will be involved.
- Conditions
- Adenovirus, Anesthesia, Anxiety, Anxiolysis
- Trial name
- PTN_POPS (NCT01431326)
- Testing
- The POPS study is collecting PK data on children prescribed the following drugs of interest per standard of care:
- Where
- 52 sites in United States, Canada and 3 more
- Volunteers
- 3,520 people
- Sponsor
- Daniel Benjamin
Anesthesia; Functional
Neuromuscular Blockade Reversal Agent Effect on Postoperative Cognitive Function and Behaviour in Children
The aim of this prospective randomized study is to investigate comparatively the effect of neostigmine-atropine versus sugammadex on speed and quality of recovery and on postoperative cognitive function \& behavior in children…
- Trial name
- NCT02455921
- Testing
- neostigmine - atropine, Sugammadex
- Where
- Greece
- Volunteers
- 200 people
- Sponsor
- Attikon Hospital
Neuromuscular Blockade
Depth of Neuromuscular Blockade and the Perioperative Conditions in Laparoscopic Surgery in Pediatric Population
This randomized study prospectively evaluates our experience with administration of cisatracurium and rocuronium antagonized by sugammadex and evaluates the effects of various depths of neuromuscular blockage on providing optimal…
- Trial name
- PedLapBlock (NCT02546843)
- Testing
- Rocuronium, Cisatracurium, Nonspecific Neuromuscular Blockade reversal
- Where
- Czechia
- Volunteers
- 66 people
- Sponsor
- Brno University Hospital
Deep Breathing Maneuver, PROGRESSIVE MUSCLE RELAXATION EXERCISES
SHORT-TERM EFFECTS OF DEEP BREATHING AND PROGRESSIVE MUSCLE RELAXATION EXERCISES ON MUSCULOSKELETAL PAIN AND WELL-BEING IN HIGH SCHOOL STUDENTS
Exam stress in high school students, long hours of studying in the static posture, and lack of physical activity habits can cause physical and psychological discomfort in them.
- Trial name
- Deep breathing (NCT06972173)
- Testing
- DEEP BREATHING AND PROGRESSIVE MUSCLE RELAXATION EXERCISES
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Kırklareli University
ARDS, Lung Protective Ventilation
Effect of Different Depths of Neuromuscular Blockade on Respiratory Mechanics in Patients With Moderate-severe Acute Respiratory Distress Syndrome
Acute respiratory distress syndrome (ARDS) is characterized by acute diffuse alveolar injury caused by a variety of pulmonary and extrapulmonary factors, leading to refractory hypoxemia. It has high incidence and mortality rates.
- Trial name
- ARDS (NCT06514209)
- Testing
- cisatracurium
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Southeast University, China
Anesthetics, Inhalation, Neuromuscular Blockade
Effect of Rocuronium and Sugammadex Under Sevoflurane and Desflurane Anesthesia in Children
Sugammadex is the first selective relaxant binding agent approved to reverse certain non-depolarizing neuromuscular drugs in patients 2 years old and above.
- Conditions
- Anesthetics, Inhalation, Neuromuscular Blockade, Anesthesia, General
- Trial name
- NCT03795259
- Testing
- Rocuronium, Sugammadex
- Where
- Turkey (Türkiye)
- Volunteers
- 148 people
- Sponsor
- Istanbul University
Anesthesia, Neuromuscular Blockade
International Focus Group Discussion on Neuromuscular Monitoring.
Focus-Group based discussion designed to gain more in-depth information on factors that could lead to an increase in the adoption of neuromuscular monitoring taking into account different country-specific contexts.
- Conditions
- Anesthesia, Neuromuscular Blockade, Neuromuscular Block, Residual, Perioperative/Postoperative Complications
- Trial name
- NCT06945341
- Testing
- Focus-Group discussion
- Where
- Belgium
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Anesthesia
Dexmetomidine in Children Undergoing General Anaesthesia
The effects of dexmedetomidine on the onset of both the general anaesthesia induction and the neuromuscular blockade in children of school age will be investigated.
- Trial name
- NCT03923075
- Testing
- Dexmedetomidine, 0.9% saline
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Attikon Hospital
Neuromuscular Blockade
Mindray Neuromuscular Transmission Transducer
A new NMT module from Mindray (Mindray Co. Shenzhen, People's Republic of China.) claims to measure 3 directional accelerography.
- Trial name
- NMT1 (NCT02892045)
- Testing
- MMG
- Where
- 2 sites in Bosnia and Herzegovina, China
- Volunteers
- 48 people
- Sponsor
- Suez Canal University
Endotracheal Intubation, Hemodynamics
Endotracheal Intubation Using Bonfils Fibrescope Without Neuromuscular Blockade
We studied intubating conditions and hemodynamic changes during endotracheal intubation employing either Bonfils intubating fiberscope or the conventional Macintosh laryngoscopy in 80 healthy patients candidates for elective…
- Conditions
- Endotracheal Intubation, Hemodynamics, Neuromuscular Blockade
- Trial name
- NCT00620386
- Testing
- Bonfils, Macintosh
- Where
- Iran
- Volunteers
- 80 people
- Sponsor
- Tehran University of Medical Sciences
Neuromuscular Blockade
Efficacy, Safety, and Pharmacokinetics of Sugammadex (MK-8616) for Reversal of Neuromuscular Blockade in Pediatric Participants Aged Birth to <2 Years (MK-8616-169)
This study will evaluate the efficacy, safety, and pharmacokinetics (PK) of sugammadex (MK-8616) for reversal of both moderate and deep neuromuscular blockade (NMB) in pediatric participants aged birth to <2 years.
- Trial name
- NCT03909165
- Testing
- Sugammadex 2 mg/kg, Sugammadex 4 mg/kg, Neostigmine + Glycopyrrolate
- Where
- 39 sites in United States, Australia and 12 more
- Volunteers
- 145 people
- Sponsor
- Merck Sharp & Dohme LLC
Headache, Headache Disorders
Responding With Evidence and Access for Childhood Headaches
This comparative effectiveness study will clarify current first-line preventive treatment approaches for use by neurologists, psychologists, and primary care providers in the context of real world care, and will demonstrate the…
- Conditions
- Headache, Headache Disorders, Headache, Migraine, Migraine
- Trial name
- NCT05889624
- Testing
- CBT, Amitriptyline
- Where
- 15 sites in United States
- Volunteers
- 400 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Acupuncture, Tumor, Brain
Evaluation of Acupuncture Effects for Complications After Surgery of Cerebellopontine Angle Tumor in Skull Base
Skull base tumors are a type of tumor that grow in the area of several skulls behind the cranial cavity. The incidence rate is 2 to 18 per 100,000 people per year; males and females are likely to have a proportional difference in…
- Conditions
- Acupuncture, Tumor, Brain, Skull Base Tumor, Cerebellopontine Angle Tumor
- Trial name
- NCT04249921
- Where
- Taiwan
- Volunteers
- 32 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Neuromuscular Blockade
Use of Neuromuscular Blocking Agents and Neuromuscular Monitoring in 7 Danish Teaching Hospitals
Aim: To explore the frequency of use of objective neuromuscular monitoring for assessment of depth of neuromuscular blockade in general anaesthesia the incidence of residual neuromuscular blockade, and the timing of reversal of…
- Trial name
- NCT02914119
- Testing
- Rocuronium, Succinylcholine, Cisatracurium
- Where
- Denmark
- Volunteers
- 30,430 people
- Sponsor
- Jakob Louis Thomsen
Neuromuscular Blockade, Neuromuscular Block, Residual
Different Doses of Neostigmine for Reversal of Moderate Neuromuscular Blockade in Children
There is no recent information on the required dose of neostigmine for the reversal of cisatracurium-induced moderate neuromuscular blockade (NMB) [Train-of-four (TOF) count = 1-3)] in children.
- Conditions
- Neuromuscular Blockade, Neuromuscular Block, Residual, Neuromuscular Block Prolonged
- Trial name
- NCT05053594
- Testing
- Neostigmine 10 mcg/kg, Neostigmine 20 mcg/kg, Neostigmine 30 mcg/kg
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidade Catolica de Sao Paulo
Headache, Headache Disorders
Mind Body Balance for Pediatric Migraine
This study uses a factorial research design to evaluate a nurse delivered mind body intervention using different doses of 3 treatment components to determine the optimized treatment for headache day reduction.
- Conditions
- Headache, Headache Disorders, Headache, Migraine, Migraine
- Trial name
- NCT04715685
- Testing
- 40 minute session, 20 minute session, home practice e-health
- Where
- 2 sites in United States
- Volunteers
- 260 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Anesthesia, Neuromuscular Blockade
Measurement of Blood Loss in Adenotonsillectomy During General Anesthesia According to the Application of Nondepolarizing Muscle Relaxants
Although tonsillectomy is one of the most commonly performed surgeries, a review of literature reveals no articles dealing with the study of intraoperative blood loss in tonsillectomy and adenotonsillectomy according to the use…
- Conditions
- Anesthesia, Neuromuscular Blockade, Intraoperative Bleeding, Intraoperative Blood Loss
- Trial name
- NCT06399445
- Testing
- conventional cold tonsillectomy and curettage adenoidectomy, Rocuronium Bromide
- Where
- Croatia
- Volunteers
- 60 people
- Sponsor
- University Hospital of Split
Incomplete Reversal of Neuromuscular Block
The Effect of Dexamethasone on Sugammadex Reversal
The purpose of this study is to determine whether dexamethasone extends the duration of recovery from anesthesia.
- Trial name
- NCT02137395
- Testing
- Dexamethasone
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Cukurova University