Clinical trials: Body
Migraine in Children, Migraine
A Study in Children and Young People With Migraine to Learn What the Body Does to Eptinezumab
The purpose of the study is to investigate how the body absorbs, distributes, and get rid of eptinezumab when given directly into a vein.
- Trial name
- NCT04537429
- Testing
- Eptinezumab
- Where
- 9 sites in United States
- Volunteers
- 28 people
- Sponsor
- H. Lundbeck A/S
Diabetes Mellitus, Type 2
A Study to Test How New Long-acting Insulin (Insulin Icodec) Works in the Body of Children and Teenagers
Insulin icodec is a new medicine which is under development for use in humans and is not yet available at the pharmacy. It is being developed for the treatment of diabetes, a condition that causes high blood sugar levels.
- Trial name
- NCT05790681
- Testing
- Insulin icodec
- Where
- 21 sites in United States
- Volunteers
- 18 people
- Sponsor
- Novo Nordisk A/S
Exercise, Physical Activity
The Active by Choice Today (ACT) Trial to Increase Physical Activity
The increasing prevalence of obesity in U.S. children and adolescents is a major health threat to our society, especially among minority and low social economic status (SES) populations.
- Conditions
- Exercise, Physical Activity, Obesity
- Trial name
- ACT (NCT01028144)
- Testing
- Physical Activity Program, General Health Program
- Where
- United States
- Volunteers
- 1,422 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Scoliosis Idiopathic Adolescent, Scoliosis Idiopathic Adolescent Treatment
Family Education for Individuals With Adolescent Idiopathic Scoliosis
Yağmur KİRMİK, Investigation of the Effect of Family Education on Stress, Deformity Perception, Quality of Life, and Treatment Adherence in Individuals with Adolescent Idiopathic Scoliosis, Hasan Kalyoncu University, Graduate…
- Trial name
- NCT07714993
- Testing
- PSSE, individual/family education
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Hasan Kalyoncu University
Obesity, Diabete Type 2
A Cohort Study on Obese Patients' Multidisciplinary Integrated Health Management
To explore influencing factors of diabetes remission and recovery of other complications after bariatric surgery. We design a multicenter study including respective cohort and prorespective cohort of obese patients treated with…
- Conditions
- Obesity, Diabete Type 2, Bariatric Surgery
- Trial name
- ODHM (NCT07451938)
- Testing
- Bariatric surgery, Non-surgical threapy
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- China-Japan Friendship Hospital
Stage IV Melanoma, Recurrent Melanoma
Vaccine Therapy With or Without Interleukin-2 in Treating Patients With Metastatic Melanoma
RATIONALE: Vaccines made from DNA may make the body build an immune response to kill tumor cells. Interleukin-2 may stimulate a person's white blood cells to kill melanoma cells.
- Trial name
- NCT00019448
- Testing
- gp100 antigen, interleukin-2
- Where
- United States
- Sponsor
- National Cancer Institute (NCI)
Obesity, Childhood
Effects of Auricular Acupressure Versus Intermittent Dietary Restriction in Children With Gastric Heat and Dampness Obstruction
This is a three-month randomized controlled trial to investigate the effects of auricular acupressure versus Intermittent carbohydrate restriction on cardiometabolic risk in obese children with gastric heat and dampness…
- Trial name
- NCT05847478
- Testing
- Auricular acupressure of traditional Chinese Medicine, Intermittent low carbohydrate diet, Health education
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Children's Hospital of Fudan University
Social-emotional Competence
Body-oriented Interventions on Preschoolers' Social-emotional Competence
Experimental study with 4 groups (3 experimental and 1 control). Examine the effects of 3 body-oriented intervention programs on preschoolers' social-emotional competence.
- Trial name
- NCT05729815
- Testing
- Relaxation, Loose parts play, Combined
- Where
- Portugal
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Évora
Obesity
Anthropometric Assessment of Abdominal Obesity and Health Risk in Children and Adolescents
Childhood obesity is a major public health issue, and the identification of children who are at increased risk of health problems due to their obesity is a priority for modern health care.
- Trial name
- Waist (NCT01595100)
- Where
- United States
- Volunteers
- 423 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Down Syndrome, Trisomy 21
Down Syndrome Metabolic Health Study
The purpose of this research study is to determine which measures best capture cardiovascular disease (CVD) risk and type 2 diabetes (T2DM) risk in children and adolescents with Down syndrome (DS).
- Trial name
- NCT01821300
- Where
- 2 sites in United States
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Body Weight Changes, Feeding and Eating Disorders of Childhood
Adjusted Individual Oral Feeding for Improving Short and Long Term Outcomes of Preterm Infants
The authors hypothesize that adjusted individual feeding (AIF) for preterm infant starting from transition to oral feeding (33 weeks corrected age) will result in less episodes of apnea/bradycardia, early achievement of full oral…
- Conditions
- Body Weight Changes, Feeding and Eating Disorders of Childhood, Breast Feeding, Evoked Response Audiometry
- Trial name
- NCT01989871
- Testing
- Adjusted individual feeding
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Sheba Medical Center
Childhood Obesity, Overweight and Obesity
Childhood Obesity - Prevention of Diabetes Through Changed Eating Patterns
The main purpose of the present study is to perform a 10 weeks dietary intervention study with a follow-up for 52 weeks in children from 7-14 years of age with overweight or obesity.
- Conditions
- Childhood Obesity, Overweight and Obesity, Adolescent Obesity, Adolescent Overweight
- Trial name
- COPE (NCT04522921)
- Testing
- Diet with a higher amount of protein (25E% per day), Increased follow-up contact after the 10-week intervention, Diet with a lower amount of protein (15E% per day)
- Where
- 2 sites in Denmark
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Obesity, Schizophrenia
Bariatric Surgery in Patients With Schizophrenia
It is known that schizophrenia is associated with obesity in a significant number of patients and it implies a poor prognostic factor, with weight loss being important in this population.
- Trial name
- SCHIZOBAR (NCT06043206)
- Testing
- Bariatric Surgery
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Obesity, Diabetes
The Effects of Carbohydrate Source on Food Intake, Blood Glucose and Gut Hormone Response in Healthy Children
This study will compare the effects of commonly consumed carbohydrate sources such as potatoes, pasta and rice along with a fixed portion of meat on blood glucose, satiety and insulin levels among healthy body weight children.
- Trial name
- NCT02499107
- Testing
- Rice treatment, Pasta treatment, Boiled and mashed potato treatment
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Obesity, Physical Activity
Reducing Television Viewing To Prevent Obesity in Hispanic Preschool Children
Obesity has been linked to the development of multiple cancers, and to poorer prognoses and higher mortality rates for certain pediatric and adult cancers.
- Conditions
- Obesity, Physical Activity, Sedentary Activity, Television Viewing
- Trial name
- NCT01216306
- Testing
- Television reduction curriculum
- Where
- United States
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Obesity
A Pilot Study of the Efficacy and Program Cost-effectiveness of Prevention Plus for Childhood Obesity
In 2007 the Expert Committee published recommendations on the prevention and treatment of childhood obesity. These recommendations outlined four interventions intended for advancement based on the child's age, body mass index…
- Trial name
- NCT01358448
- Testing
- growth monitoring, Growth Monitoring plus Family-based Behavioral Counseling
- Where
- 2 sites in United States
- Volunteers
- 22 people
- Sponsor
- The University of Tennessee, Knoxville
Overweight and Obesity
Inhibitory Control and Pediatric Weight Management
The purpose of this pilot study is to explore the benefits of supplementing the Kurbo online program with a cognitive training game (PolyRules!) among youth ages 7-13 with overweight or obesity.
- Trial name
- NCT04747548
- Testing
- Kurbo Only, Kurbo + PolyRules!
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Vitamin D Deficiency, Obesity
Vitamin D Deficiency and Low Bone Mineral Content in Children
The Vitamin D study is designed to investigate the effect of body fat mass on vitamin D levels in children. Earlier studies have shown that individuals with increased fat mass may have low vitamin D levels.
- Trial name
- VDS (NCT00756899)
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Childhood Obesity, Cardiovascular Disease
The Effects of California Strawberries on Parameters of Cardiovascular Health
The prevalence of childhood obesity has been increasing over the past couple of decades. Similar to adults, overweight and obesity in young children and adolescents is associated with an increased number of cardiovascular risk…
- Trial name
- NCT01705093
- Testing
- flavonoid-rich freeze-dried strawberry powder, macronutrient-matched control powder
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Diabetes (DM), Hypertension
Multimodal Cardiovascular Magnetic Resonance Imaging for Cardiometabolic Pre-HF and HFpEF
This is an observational study aiming to characterize the pathophysiological features and clinical significance of cardiometabolic early-stage heart failure using advanced multimodal cardiovascular magnetic resonance (CMR)…
- Conditions
- Diabetes (DM), Hypertension, Heart Failure, Obesity & Overweight
- Trial name
- NCT07336316
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
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