Clinical trials: Body Temperature Changes
Pyrexia, COVID
COVID-19 Thales Thermography Triage : Thermal Camera Feasibility Study
This study will refine and pilot the feasibility of introducing a thermal imaging test to detect fever in 100 patients being triaged within the Emergency Department.
- Trial name
- COVID3T (NCT04397380)
- Testing
- Thermography, Tympanic Temperature
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- NHS Greater Clyde and Glasgow
Preterm Delivery, Hypothermia
Randomized Controlled Trial of Social Network Targeting in Honduras
Social network targeting strategies can be used to improve the delivery and uptake of health interventions. We will enroll approximately 30,000 individuals into a randomized controlled trial of different targeting algorithms in…
- Conditions
- Preterm Delivery, Hypothermia, Diarrhea, Upper Respiratory Infection
- Trial name
- NCT02694679
- Testing
- CBNH
- Where
- 2 sites in United States, Honduras
- Volunteers
- 31,195 people, healthy volunteers welcome
- Sponsor
- Yale University
Hypothermia
Pharmacokinetics of Ampicillin in Neonates With Moderate to Severe Hypoxic-Ischemic Encephalopathy
Controlled Hypothermia has become the standard of care for neonates with moderate to severe HIE. Ampicillin and aminoglycosides are drugs that are universally used for the treatment of suspected neonatal sepsis, which may or may…
- Trial name
- NCT03129620
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Drexel University
Fever
Acetaminophen Concentration in Cerebrospinal Fluid in Infants
Acetaminophen is the most commonly used drug in children. Inhibition of COX-3 in the brain has been suggested as the primary central mechanism by which acetaminophen decrease pain and possibly fever.
- Trial name
- NCT00389454
- Where
- Israel
- Sponsor
- Assaf-Harofeh Medical Center
Preterm Infants
Weaning Preterm Infants at 1500 Grams From Incubators
Background: The weight at which infants are weaned from incubators varies among neonatal units. Objective: To determine the effect on weight gain, temperature stability and resting energy expenditure (REE) of weaning infants at…
- Trial name
- NCT01083303
- Testing
- Weaning Preterm Infants from an incubator
- Where
- Israel
- Volunteers
- 21 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Hand, Foot and Mouth Disease
Chinese Medicinal Treatment on Mild Hand, Foot, and Mouth Disease: Multicenter, Prospective, Randomized Double-blind, Placebo-controlled Study
The study is aimed to evaluate the effectiveness and safety of Jinlianqingre Effervescent Tablets, a traditional Chinese medicine (TCM), in the treatment of Uncomplicated hand, foot, and mouth disease (HFMD).
- Trial name
- NCT01769794
- Testing
- Western therapy, JET
- Where
- 4 sites in China
- Volunteers
- 288 people
- Sponsor
- China Academy of Chinese Medical Sciences
Infant, Premature, Hypothermia, Newborn
Cardboard Cot in Neonatal Thermoregulation: A Randomized Cross Over Trial
This study will determine whether the efficacy of Mylar-lined cardboard cots is equivalent to traditional incubators in their ability to prevent hypothermia (axillary temperature < 36° C) in preterm neonates <36 6/7 weeks…
- Trial name
- CCot (NCT03344978)
- Testing
- Cardboard Cot Care, Incubator Care
- Sponsor
- University of Alabama at Birmingham
Pediatric Oncology Patients With Risk for Infections
Swiss 2024 Continous Fever Monitoring in Pediatric Oncology Patients
In children and adolescents undergoing chemotherapy for cancer, fever in neutropenia (FN) is the most frequent potentially lethal complication of chemotherapy for cancer.
- Trial name
- NCT05940766
- Testing
- Automated fever alerts
- Where
- Switzerland
- Volunteers
- 250 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Bacterial Infections, Urinary Tract Infections
Host RNA Profiles to Detect Infections in Young Infants
This study seeks to identify and test host RNA expression profiles as markers for infections in young infants. Preliminary studies have shown high sensitivity and specificity for the discrimination of bacterial from non-bacterial…
- Conditions
- Bacterial Infections, Urinary Tract Infections, Sepsis, Fever
- Trial name
- CHILD_YIC (NCT04823026)
- Where
- 4 sites in Denmark
- Volunteers
- 152 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Juvenile Rheumatoid Arthritis
Safety and Efficacy Study of Etanercept (Enbrel®) In Children With Systemic Onset Juvenile Rheumatoid Arthritis
The primary objective of this study was to determine the efficacy of etanercept in pediatric patients with systemically active system onset juvenile rheumatoid arthritis (SOJRA).
- Trial name
- NCT00078806
- Testing
- Etanercept
- Volunteers
- 19 people
- Sponsor
- Amgen
Cardiac Arrest, Hypothermia
Hypothermia's Impact on Pharmacology
The purpose of the study will help us understand the complex interaction between hypothermia (cooling) and pharmacogenetics (how specific genes effect how drugs are handled), and their impact on how routinely given sedation drug…
- Trial name
- HIP (NCT01560338)
- Where
- 9 sites in United States
- Volunteers
- 41 people
- Sponsor
- Children's Hospital of Philadelphia
Fever
Study of an App to Facilitate Communication With Parents of Febrile Infants
The objective of this research project is to test an evidence-based parent-centered care software application (e-Care) to ensure that parents of febrile infants from a wide range of socio-demographic backgrounds are optimally…
- Trial name
- NCT04328909
- Testing
- E-Care, Control Group
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Yale University
Wearable Technology, Hypothermia
The Effect of Warmed Socks Developed as Wearable Technology on Hypothermia, Thermal Comfort Perception and Shivering
In this study, it is aimed to reveal the effect of the use of heated socks to be developed as wearable technology by providing temperature control on body temperature, comfort perception level and shivering development in healthy…
- Conditions
- Wearable Technology, Hypothermia, Shivering, Thermal Comfort Perception
- Trial name
- NCT06283771
- Testing
- Heated socks to be developed with wearable technology
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Tarsus University
Cancer, Pediatrics
SPOG 2015 FN Definition. A Multi-center Non-inferiority Trial on Safety of a High Versus Low Temperature Limit Defining Fever in Pediatric Patients With Cancer at Risk for Fever in Chemotherapy-induced Neutropenia
In a multi-center open-label cluster-randomized controlled parallel-group multiple crossover non-inferiority trial in children and adolescents up to 20 years diagnosed with cancer requiring chemotherapy, primarily the safety, and…
- Conditions
- Cancer, Pediatrics, Fever, Neutropenia
- Trial name
- NCT02324231
- Testing
- 39.0°C temperature limit defining fever, 38.5°C temperature limit defining fever
- Where
- 6 sites in Switzerland
- Volunteers
- 269 people
- Sponsor
- Swiss Pediatric Oncology Group
Hypoxic-Ischemic Encephalopathy, Asphyxia Perinatal
Identification of a Pool of miRNA to Improve Early Management of Perinatal Asphyxia and Hypoxic Ischemic Encephalopathy
Hypoxic-ischemic encephalopathy is the most common cause of neurological damage in the neonatal period. It has an incidence of about 1.5-2.5% of livebirths in developed countries.
- Trial name
- NCT05986994
- Testing
- Metabolic acidosis, microRNA, Hypothermia
- Where
- 2 sites in Italy
- Volunteers
- 45 people
- Sponsor
- Ospedale Buon Consiglio Fatebenefratelli
Asphyxia Neonatorum
Amikacin Pharmacokinetics to Optimize Dosing Recommendations in Neonates With Perinatal Asphyxia Treated With Hypothermia
As a part of a project on perinatal clinical pharmacology, the primary aim of the present project is to study amikacin pharmacokinetics (PK) and physiology in asphyxiated neonates treated with therapeutic hypothermia and to…
- Trial name
- Amicool (NCT04867993)
- Testing
- Amikacin
- Where
- Bosnia and Herzegovina
- Volunteers
- 80 people
- Sponsor
- University of Sarajevo
Cough, Myalgia
Clinical Evaluation of QFlu Combo Test
Currently effective antivials for influenza treatment are two influenza viral neuraminidase inhibitors, oseltamivir (Tamiflu) and zanamivir (Relenza).
- Conditions
- Cough, Myalgia, Nasal Obstruction, Sore Throat
- Trial name
- QFlu (NCT01506583)
- Where
- 3 sites in United States
- Volunteers
- 506 people
- Sponsor
- Cellex, Inc.
Body Temperature Changes
Radiant Warmer Trial
The purpose of this study is to compare three radiant warmer beds that contain different computer heating software and different bed styles.
- Trial name
- NCT01011855
- Testing
- GEHC IWS 4400 & Giraffe Warmer beds
- Sponsor
- GE Healthcare
Fever, Children
Study to Investigate the Causes of Fever in Children Living in Urban Dar es Salaam and Rural Ifakara
The goal is to improve the evidence-based management of fever cases seen in outpatient clinics in malaria endemic countries, through a better understanding of the value of accurate malaria diagnosis, and through an improved…
- Conditions
- Fever, Children, Infectious Diseases
- Trial name
- NCT01812785
- Where
- 2 sites in Tanzania
- Volunteers
- 1,010 people
- Sponsor
- Swiss Tropical & Public Health Institute
Fever, Malaria
Effectiveness Of Rapid Diagnostic Tests in the New Context of Low Malaria Endemicity in Zanzibar
The purpose of this study is to study the effectiveness of wide scale RDT use at the primary health care level in previously high malaria endemic area during malaria pre-elimination phase for improved targeting of anti-malarial…
- Trial name
- RDTACT (NCT01002066)
- Where
- Tanzania
- Volunteers
- 3,890 people
- Sponsor
- Karolinska University Hospital